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The map label for this gene is ycgM [C]

Identifier: 120611144

GI number: 120611144

Start: 2705154

End: 2705849

Strand: Reverse

Name: ycgM [C]

Synonym: Aave_2473

Alternate gene names: 120611144

Gene position: 2705849-2705154 (Counterclockwise)

Preceding gene: 120611147

Following gene: 120611143

Centisome position: 50.55

GC content: 69.4

Gene sequence:

>696_bases
ATGAACTACGTGATTCCTCCTGCGCCCATTCCCAGCGTGCCCGTGGCGGGCACCGCAGACCGCTTTCCGGTGCACCGCAT
CTACTGCGTCGGCCGCAACTACGAGGAGCACGCCAAGGAAATGGGCTTCACCGGCCGGGAGCCGCCCTTCTTCTTCCTCA
AGCCGGCGGACGCCATCGTCGCGGTGGAAGCGGGCGAGACGGGCCGCATGCCCTACCCCACCCTGACGGCCAACCTGCAC
CACGAGATCGAACTGGTGGTGGCCATCGGCCGCGGCGGACGCGACATCCGCGCGGCCGATGCCCCGCAGCACATCTTCGG
CTATGCCGTCGGCCTCGACATGACCCGCCGGGACCTGCAGAACGACATGAAGAAGCAGGGTCGCCCCTGGTGCATCGGCA
AGGGTTTCGAGCACAGCGCGCCGATCGGCCCGATCACGCCGGCCGCGCAGGCGGGCGACGTGGCCAGGGCCCCCATCTGG
CTGCAGGTGAACGGTGCCGACCGACAGCGCAGCACGGTCGCGCAGCTGATCTGGAACATCGCCGAAACGATCGAGCACCT
GTCCGCCGCCTGGGAACTGCAGCCCGGCGACCTCATCTTCACCGGCACGCCCGAAGGCGTGGGCGCGGTGGCGCGCGGCG
ACGTGCTGGAAGGCGGCGTCGACGGACTGGGCTCCCTGCGCGTGGAAATCGCCTGA

Upstream 100 bases:

>100_bases
AAGCATAACGTCCGTGCATGGCACACTCTGGCCGGGGCCTGCCGGCGCCTGCACGGCGCGCACGGGCCACCGCACCCCAC
CGAGACAAGGCCTGACATCC

Downstream 100 bases:

>100_bases
ACATGACCACCCGCAGGCCGATCAAGCACTGCCGTGAATGCGGGGCCGCCGTGGAGTACCGCGTGCCCGACGACGGCGAC
ACCAAGCTGCGCGCCGTCTG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MNYVIPPAPIPSVPVAGTADRFPVHRIYCVGRNYEEHAKEMGFTGREPPFFFLKPADAIVAVEAGETGRMPYPTLTANLH
HEIELVVAIGRGGRDIRAADAPQHIFGYAVGLDMTRRDLQNDMKKQGRPWCIGKGFEHSAPIGPITPAAQAGDVARAPIW
LQVNGADRQRSTVAQLIWNIAETIEHLSAAWELQPGDLIFTGTPEGVGAVARGDVLEGGVDGLGSLRVEIA

Sequences:

>Translated_231_residues
MNYVIPPAPIPSVPVAGTADRFPVHRIYCVGRNYEEHAKEMGFTGREPPFFFLKPADAIVAVEAGETGRMPYPTLTANLH
HEIELVVAIGRGGRDIRAADAPQHIFGYAVGLDMTRRDLQNDMKKQGRPWCIGKGFEHSAPIGPITPAAQAGDVARAPIW
LQVNGADRQRSTVAQLIWNIAETIEHLSAAWELQPGDLIFTGTPEGVGAVARGDVLEGGVDGLGSLRVEIA
>Mature_231_residues
MNYVIPPAPIPSVPVAGTADRFPVHRIYCVGRNYEEHAKEMGFTGREPPFFFLKPADAIVAVEAGETGRMPYPTLTANLH
HEIELVVAIGRGGRDIRAADAPQHIFGYAVGLDMTRRDLQNDMKKQGRPWCIGKGFEHSAPIGPITPAAQAGDVARAPIW
LQVNGADRQRSTVAQLIWNIAETIEHLSAAWELQPGDLIFTGTPEGVGAVARGDVLEGGVDGLGSLRVEIA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=204, Percent_Identity=40.1960784313725, Blast_Score=160, Evalue=8e-40,
Organism=Homo sapiens, GI215422413, Length=197, Percent_Identity=41.1167512690355, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI66348062, Length=197, Percent_Identity=41.1167512690355, Blast_Score=158, Evalue=4e-39,
Organism=Homo sapiens, GI156231349, Length=230, Percent_Identity=31.7391304347826, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI40786394, Length=230, Percent_Identity=30.8695652173913, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1787428, Length=204, Percent_Identity=40.1960784313725, Blast_Score=149, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17557057, Length=201, Percent_Identity=37.3134328358209, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6324161, Length=219, Percent_Identity=32.4200913242009, Blast_Score=119, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28571789, Length=206, Percent_Identity=31.0679611650485, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28572127, Length=214, Percent_Identity=31.3084112149533, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24663695, Length=212, Percent_Identity=26.8867924528302, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 24905; Mature: 24905

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYVIPPAPIPSVPVAGTADRFPVHRIYCVGRNYEEHAKEMGFTGREPPFFFLKPADAIV
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCEEEECCCCEEE
AVEAGETGRMPYPTLTANLHHEIELVVAIGRGGRDIRAADAPQHIFGYAVGLDMTRRDLQ
EEECCCCCCCCCCEEECCCCEEEEEEEEECCCCCCCCCCCCCHHHHEEEECCCHHHHHHH
NDMKKQGRPWCIGKGFEHSAPIGPITPAAQAGDVARAPIWLQVNGADRQRSTVAQLIWNI
HHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
AETIEHLSAAWELQPGDLIFTGTPEGVGAVARGDVLEGGVDGLGSLRVEIA
HHHHHHHHHHEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MNYVIPPAPIPSVPVAGTADRFPVHRIYCVGRNYEEHAKEMGFTGREPPFFFLKPADAIV
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCEEEECCCCEEE
AVEAGETGRMPYPTLTANLHHEIELVVAIGRGGRDIRAADAPQHIFGYAVGLDMTRRDLQ
EEECCCCCCCCCCEEECCCCEEEEEEEEECCCCCCCCCCCCCHHHHEEEECCCHHHHHHH
NDMKKQGRPWCIGKGFEHSAPIGPITPAAQAGDVARAPIWLQVNGADRQRSTVAQLIWNI
HHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
AETIEHLSAAWELQPGDLIFTGTPEGVGAVARGDVLEGGVDGLGSLRVEIA
HHHHHHHHHHEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]