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The map label for this gene is 120611142

Identifier: 120611142

GI number: 120611142

Start: 2703238

End: 2704590

Strand: Reverse

Name: 120611142

Synonym: Aave_2471

Alternate gene names: NA

Gene position: 2704590-2703238 (Counterclockwise)

Preceding gene: 120611143

Following gene: 120611138

Centisome position: 50.53

GC content: 72.14

Gene sequence:

>1353_bases
TTGCGGCCCGGTATCCCGGACACCATGACCGATGACCTGCAGCGCCTGCGCGCTGGCGACCTCGCGGGTGCGCGCGTGCT
GCGCATCGCCGCCGGCCTGGAGCATTTTCCACGCGAGATCTTCGACCTGGCCGATACGCTGGAGGTGCTGGACCTCTCCG
GCAACCGCCTCTCGGCGCTGCCCGATGACCTGCATCGGCTGCACCGGCTGAAGGTGTTCTTCGCCTCGTCCAACCGCTTC
GCCGAGCTGCCCGCTGCCCTGGGCGACTGCCCGCAACTGGAGATGGTGGGCTTCAAGGCCAACCGCATCGCCCACGTGCC
GGCCCGGTCGCTGCCCGCGCGGCTGCGCTGGCTGATCCTGACGGACAACGCCATCACGGAGTTGCCCGACGCCCTGGGGC
AGCGGCCCCGGCTGCAGAAGCTGATGCTGGCCGGCAACCTGCTGCGCACCTTGCCCGATACGCTGCGGCAGTGCGCGTCG
CTGGAACTGCTGCGCGTTGCCGCCAACCGGCTCGACGCCCTCCCCGGCTGGCTGGCCGGCCTGCCGCGGCTCGCCTGGCT
GGCCATCGGCGGCAACGCGTTCAACGAAGCCTCCGAGGAGCTCGCACGCTGCAGCCAGGCCGCCGGCCATGTGGACTGGA
GCTGCCTGCAGCTGGGCGAACTGCTGGGGGAAGGCGCCTCCGGTCGCATCATGGCGGGCCGGCTGGAGAGCGCCGCCGGC
AGGCGTGAGGTGGCCGTCAAGCTTTTCAAGGGCGAGGTCACGAGCGATGGCTGGCCACTGACCGAGATGGCAGCCAGCCT
GGCCGCCGGACGGCATCCGCGGCTGATCCCGGTGCTGGGGCGGCTCGATGGCCACCCGGACGGCGCGCAGGGCCTGGTGA
TGGAACGCATCTCCACGAACTACCGCACGCTGGCCGGCCCGCCCAGCTTCGAGAGCTGCACCCGCGATGTCTATCCGGCC
GGCCTGCGGCTGCCTGCCTTCGTGGCATTGCGCATCGCGGCGGATGTGGCGTCCGCGCTGGCACATCTGCATGGCCGGGG
GCTGGTGCACGGCGACCTGTATGCGCACAACCTGCTGTGGCGTCCGCATGCACCTGCCGGCCAGGCGGCCGGCCTGCTGG
GAGACTTCGGCGCCGCCGCGTTCGCGCCGCCCGGAGCGCTGGGCGATGCGCTGCGCCGCATGGACGTGCGGGCTTTCGGC
GTGCTGCTGGCCGAACTGTGCGCCCATGCCGATGGACCATTGCCCGACGGCGGCGCTCCGGCGCTGGCGGCAGTCTGCCT
GCACGAAGACCCGGCCGCCCGGCCCGATGCCGCCGCACTGGCCGTACGCACGGCGCAGTGGATGGCAGGCTGA

Upstream 100 bases:

>100_bases
GTTCCGCACGGTCAAGGTGACGCTCGAGAAATACTTCGCCGACCGCCGCTCGGGCGCTTTCGGCATGCACTGCGTCGATA
TCGATTGACCCACCCGGGCC

Downstream 100 bases:

>100_bases
ACGGCTCAGGCCGGCAGACCCGCCCGCACGTTCACTTGAGCCACTTGTCGGCCGCCTGCTTGAGCTGGCCGCGGGCTTCC
ATCAGGCCCCAGACGAACTC

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: Leucine-Rich Repeat-Containing Protein; Protein Kinase; Leucine-Rich Repeat Protein; Cytoplasmic Membrane Protein; Leucine-Rich Repeat-Containing Protein Kinase; Ras Family; Miro-Like Protein; Outer Membrane Protein; Protein Kinase Domain-Containing Protein; Kinase; Phosphoprotein Phosphatase; Leucine Rich Repeat Domain Protein; Serine/Threonine-Protein Kinase-Like Domain Protein; Miro Domain Protein; Outermembrane Protein; Miro Domain-Containing Protein; Serine/Threonine-Protein Kinase-Like Domain; Protein KinaseLeucine-Rich Repeat Protein; Lipoprotein

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MRPGIPDTMTDDLQRLRAGDLAGARVLRIAAGLEHFPREIFDLADTLEVLDLSGNRLSALPDDLHRLHRLKVFFASSNRF
AELPAALGDCPQLEMVGFKANRIAHVPARSLPARLRWLILTDNAITELPDALGQRPRLQKLMLAGNLLRTLPDTLRQCAS
LELLRVAANRLDALPGWLAGLPRLAWLAIGGNAFNEASEELARCSQAAGHVDWSCLQLGELLGEGASGRIMAGRLESAAG
RREVAVKLFKGEVTSDGWPLTEMAASLAAGRHPRLIPVLGRLDGHPDGAQGLVMERISTNYRTLAGPPSFESCTRDVYPA
GLRLPAFVALRIAADVASALAHLHGRGLVHGDLYAHNLLWRPHAPAGQAAGLLGDFGAAAFAPPGALGDALRRMDVRAFG
VLLAELCAHADGPLPDGGAPALAAVCLHEDPAARPDAAALAVRTAQWMAG

Sequences:

>Translated_450_residues
MRPGIPDTMTDDLQRLRAGDLAGARVLRIAAGLEHFPREIFDLADTLEVLDLSGNRLSALPDDLHRLHRLKVFFASSNRF
AELPAALGDCPQLEMVGFKANRIAHVPARSLPARLRWLILTDNAITELPDALGQRPRLQKLMLAGNLLRTLPDTLRQCAS
LELLRVAANRLDALPGWLAGLPRLAWLAIGGNAFNEASEELARCSQAAGHVDWSCLQLGELLGEGASGRIMAGRLESAAG
RREVAVKLFKGEVTSDGWPLTEMAASLAAGRHPRLIPVLGRLDGHPDGAQGLVMERISTNYRTLAGPPSFESCTRDVYPA
GLRLPAFVALRIAADVASALAHLHGRGLVHGDLYAHNLLWRPHAPAGQAAGLLGDFGAAAFAPPGALGDALRRMDVRAFG
VLLAELCAHADGPLPDGGAPALAAVCLHEDPAARPDAAALAVRTAQWMAG
>Mature_450_residues
MRPGIPDTMTDDLQRLRAGDLAGARVLRIAAGLEHFPREIFDLADTLEVLDLSGNRLSALPDDLHRLHRLKVFFASSNRF
AELPAALGDCPQLEMVGFKANRIAHVPARSLPARLRWLILTDNAITELPDALGQRPRLQKLMLAGNLLRTLPDTLRQCAS
LELLRVAANRLDALPGWLAGLPRLAWLAIGGNAFNEASEELARCSQAAGHVDWSCLQLGELLGEGASGRIMAGRLESAAG
RREVAVKLFKGEVTSDGWPLTEMAASLAAGRHPRLIPVLGRLDGHPDGAQGLVMERISTNYRTLAGPPSFESCTRDVYPA
GLRLPAFVALRIAADVASALAHLHGRGLVHGDLYAHNLLWRPHAPAGQAAGLLGDFGAAAFAPPGALGDALRRMDVRAFG
VLLAELCAHADGPLPDGGAPALAAVCLHEDPAARPDAAALAVRTAQWMAG

Specific function: Unknown

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI187829877, Length=179, Percent_Identity=32.4022346368715, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI62241040, Length=179, Percent_Identity=32.4022346368715, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI187829871, Length=179, Percent_Identity=32.4022346368715, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI238908508, Length=187, Percent_Identity=31.0160427807487, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI55770895, Length=175, Percent_Identity=29.7142857142857, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI16904383, Length=188, Percent_Identity=30.3191489361702, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI8923909, Length=174, Percent_Identity=29.8850574712644, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI122937315, Length=236, Percent_Identity=31.3559322033898, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI19923729, Length=179, Percent_Identity=29.0502793296089, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI95113664, Length=205, Percent_Identity=28.780487804878, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI197333706, Length=175, Percent_Identity=28, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI34222199, Length=175, Percent_Identity=28, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI110825984, Length=222, Percent_Identity=29.2792792792793, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI62912472, Length=188, Percent_Identity=35.1063829787234, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI197333692, Length=179, Percent_Identity=30.1675977653631, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI21245134, Length=179, Percent_Identity=30.1675977653631, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI62912470, Length=193, Percent_Identity=35.7512953367876, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI63003903, Length=179, Percent_Identity=29.608938547486, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI41281398, Length=193, Percent_Identity=29.0155440414508, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI33859670, Length=160, Percent_Identity=31.25, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI33285015, Length=165, Percent_Identity=34.5454545454545, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI256017180, Length=160, Percent_Identity=31.25, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI256017174, Length=160, Percent_Identity=31.25, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI45827729, Length=184, Percent_Identity=30.9782608695652, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI45827731, Length=184, Percent_Identity=30.9782608695652, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI34577083, Length=151, Percent_Identity=33.7748344370861, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI6912638, Length=151, Percent_Identity=33.7748344370861, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI40217803, Length=220, Percent_Identity=30, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI53729363, Length=135, Percent_Identity=31.8518518518519, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI53729359, Length=135, Percent_Identity=31.8518518518519, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI53729361, Length=135, Percent_Identity=31.8518518518519, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI194394161, Length=209, Percent_Identity=25.3588516746411, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI61742784, Length=154, Percent_Identity=37.6623376623377, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI299758423, Length=135, Percent_Identity=31.8518518518519, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI61742786, Length=154, Percent_Identity=37.6623376623377, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI21389431, Length=177, Percent_Identity=31.0734463276836, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI157743290, Length=128, Percent_Identity=32.03125, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI154091020, Length=182, Percent_Identity=27.4725274725275, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI21361633, Length=157, Percent_Identity=29.9363057324841, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17550406, Length=161, Percent_Identity=36.0248447204969, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71991531, Length=189, Percent_Identity=31.2169312169312, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71991525, Length=189, Percent_Identity=31.2169312169312, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71993778, Length=205, Percent_Identity=31.219512195122, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71993783, Length=205, Percent_Identity=31.219512195122, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17510303, Length=153, Percent_Identity=30.718954248366, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71981160, Length=173, Percent_Identity=31.7919075144509, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71981152, Length=186, Percent_Identity=31.7204301075269, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71998904, Length=181, Percent_Identity=31.4917127071823, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71998900, Length=181, Percent_Identity=31.4917127071823, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17537883, Length=181, Percent_Identity=31.4917127071823, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17552452, Length=186, Percent_Identity=31.7204301075269, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19922294, Length=168, Percent_Identity=35.7142857142857, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI62472958, Length=210, Percent_Identity=30.952380952381, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24650336, Length=229, Percent_Identity=31.0043668122271, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24650330, Length=210, Percent_Identity=30.952380952381, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24650334, Length=210, Percent_Identity=30.952380952381, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24650332, Length=210, Percent_Identity=30.952380952381, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI116007092, Length=210, Percent_Identity=30.952380952381, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281362653, Length=210, Percent_Identity=30.952380952381, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281362651, Length=210, Percent_Identity=30.952380952381, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281362657, Length=210, Percent_Identity=30.952380952381, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI281362655, Length=210, Percent_Identity=30.952380952381, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI18858105, Length=206, Percent_Identity=28.1553398058252, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI221379725, Length=142, Percent_Identity=34.5070422535211, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221379722, Length=142, Percent_Identity=34.5070422535211, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19922706, Length=149, Percent_Identity=28.1879194630872, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17933612, Length=184, Percent_Identity=32.0652173913043, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47871; Mature: 47871

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPGIPDTMTDDLQRLRAGDLAGARVLRIAAGLEHFPREIFDLADTLEVLDLSGNRLSAL
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PDDLHRLHRLKVFFASSNRFAELPAALGDCPQLEMVGFKANRIAHVPARSLPARLRWLIL
HHHHHHHHHHHEEEECCCCHHHHHHHHCCCCCEEEECCCCCCEEECCCCCCCCEEEEEEE
TDNAITELPDALGQRPRLQKLMLAGNLLRTLPDTLRQCASLELLRVAANRLDALPGWLAG
ECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LPRLAWLAIGGNAFNEASEELARCSQAAGHVDWSCLQLGELLGEGASGRIMAGRLESAAG
HHHHHEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEECHHHHCCC
RREVAVKLFKGEVTSDGWPLTEMAASLAAGRHPRLIPVLGRLDGHPDGAQGLVMERISTN
HHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEHHHHCCCCCCCCCCHHHHHHHCCC
YRTLAGPPSFESCTRDVYPAGLRLPAFVALRIAADVASALAHLHGRGLVHGDLYAHNLLW
CEECCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHCEE
RPHAPAGQAAGLLGDFGAAAFAPPGALGDALRRMDVRAFGVLLAELCAHADGPLPDGGAP
CCCCCCCCHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
ALAAVCLHEDPAARPDAAALAVRTAQWMAG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPGIPDTMTDDLQRLRAGDLAGARVLRIAAGLEHFPREIFDLADTLEVLDLSGNRLSAL
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PDDLHRLHRLKVFFASSNRFAELPAALGDCPQLEMVGFKANRIAHVPARSLPARLRWLIL
HHHHHHHHHHHEEEECCCCHHHHHHHHCCCCCEEEECCCCCCEEECCCCCCCCEEEEEEE
TDNAITELPDALGQRPRLQKLMLAGNLLRTLPDTLRQCASLELLRVAANRLDALPGWLAG
ECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LPRLAWLAIGGNAFNEASEELARCSQAAGHVDWSCLQLGELLGEGASGRIMAGRLESAAG
HHHHHEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEECHHHHCCC
RREVAVKLFKGEVTSDGWPLTEMAASLAAGRHPRLIPVLGRLDGHPDGAQGLVMERISTN
HHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEHHHHCCCCCCCCCCHHHHHHHCCC
YRTLAGPPSFESCTRDVYPAGLRLPAFVALRIAADVASALAHLHGRGLVHGDLYAHNLLW
CEECCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHCEE
RPHAPAGQAAGLLGDFGAAAFAPPGALGDALRRMDVRAFGVLLAELCAHADGPLPDGGAP
CCCCCCCCHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
ALAAVCLHEDPAARPDAAALAVRTAQWMAG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA