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The map label for this gene is dnaQ [H]

Identifier: 120611120

GI number: 120611120

Start: 2672955

End: 2673686

Strand: Direct

Name: dnaQ [H]

Synonym: Aave_2449

Alternate gene names: 120611120

Gene position: 2672955-2673686 (Clockwise)

Preceding gene: 120611119

Following gene: 120611121

Centisome position: 49.94

GC content: 62.7

Gene sequence:

>732_bases
ATGACGCGGCAGATCGTTCTCGATACCGAAACCACGGGCCTGTCCGCGGAGGGTGGCGACCGCATCATCGAACTGGGATG
CGTGGAGCTGTTGAACCGCAAACTGACCGGCAACAACCTGCACCTGTACTTCAACCCGGAGCGCGACAGCCACGAGGACG
CGCTGAAGGTGCACGGCATCAGCAACGAGTTCCTGAAGGACAAGCCCAAGTTCGCCGAGGTGGTGGACGAGATCCTGGAA
TACCTCCAGGGTGCTGAAATCATCATCCACAACGCGGCCTTCGACGTGGGCTTCCTGAACAAGGAGCTGGAGCTGACGGG
TCGTCCCGCGTTCACCAGCTACGTCGAGAGCGTGACGGACACGCTGGTGATGGCCAAGGAGATGTACCCGGGCAAGCGCA
ACTCGCTGGACGCGCTGTGCGACCGGCTGGGCGTGGACAACTCCGGTCGTACGCTGCACGGGGCGCTGCTGGACGCGGAG
CTGCTGGCCGATGTGTACATCAACCTCACGCGCGGCCAGGATGCGCTGCTGATCGCCGACGACGCGCAGGAGGGCGATGA
AACCGCCGTGCGCCTGGCGCCCGTGGATCTTTCGGCCTTCACGCTGCCGGTGCTCCTGGCCAGCGAGCAGGAACTGGCTG
CGCACGACGAAGTCCTGGCCCAGATCGACAAGGCCAGCGGCGGCAAAACTATTTGGAAAATTTCTTCGGACGGCCAAAAA
GCTATGCCATAA

Upstream 100 bases:

>100_bases
ATTCCAAAGTACACGATCAACCATGCCAAGGAGAACCACTGATGCAGGCCCAGGCTGAATTCCGCCCGGTCGGTACCGCG
GCATGTGCAGGAGGCCGGGC

Downstream 100 bases:

>100_bases
TCATGGGCTGCCGCAACAACGGCACTGGGGTGATTAGCTCAGCGGTAGAGCACTGCCTTCACACGGCAGGGGTCACATGT
TCGATCCATGTATCACCCAC

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MTRQIVLDTETTGLSAEGGDRIIELGCVELLNRKLTGNNLHLYFNPERDSHEDALKVHGISNEFLKDKPKFAEVVDEILE
YLQGAEIIIHNAAFDVGFLNKELELTGRPAFTSYVESVTDTLVMAKEMYPGKRNSLDALCDRLGVDNSGRTLHGALLDAE
LLADVYINLTRGQDALLIADDAQEGDETAVRLAPVDLSAFTLPVLLASEQELAAHDEVLAQIDKASGGKTIWKISSDGQK
AMP

Sequences:

>Translated_243_residues
MTRQIVLDTETTGLSAEGGDRIIELGCVELLNRKLTGNNLHLYFNPERDSHEDALKVHGISNEFLKDKPKFAEVVDEILE
YLQGAEIIIHNAAFDVGFLNKELELTGRPAFTSYVESVTDTLVMAKEMYPGKRNSLDALCDRLGVDNSGRTLHGALLDAE
LLADVYINLTRGQDALLIADDAQEGDETAVRLAPVDLSAFTLPVLLASEQELAAHDEVLAQIDKASGGKTIWKISSDGQK
AMP
>Mature_242_residues
TRQIVLDTETTGLSAEGGDRIIELGCVELLNRKLTGNNLHLYFNPERDSHEDALKVHGISNEFLKDKPKFAEVVDEILEY
LQGAEIIIHNAAFDVGFLNKELELTGRPAFTSYVESVTDTLVMAKEMYPGKRNSLDALCDRLGVDNSGRTLHGALLDAEL
LADVYINLTRGQDALLIADDAQEGDETAVRLAPVDLSAFTLPVLLASEQELAAHDEVLAQIDKASGGKTIWKISSDGQKA
MP

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=243, Percent_Identity=49.7942386831276, Blast_Score=238, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26549; Mature: 26418

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRQIVLDTETTGLSAEGGDRIIELGCVELLNRKLTGNNLHLYFNPERDSHEDALKVHGI
CCCEEEEECCCCCCCCCCCCEEEHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEECC
SNEFLKDKPKFAEVVDEILEYLQGAEIIIHNAAFDVGFLNKELELTGRPAFTSYVESVTD
CHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECEECEEECCCEEEECCCCHHHHHHHHHHH
TLVMAKEMYPGKRNSLDALCDRLGVDNSGRTLHGALLDAELLADVYINLTRGQDALLIAD
HHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHEEEECCCCEEEEEC
DAQEGDETAVRLAPVDLSAFTLPVLLASEQELAAHDEVLAQIDKASGGKTIWKISSDGQK
CCCCCCCCEEEEEECCCHHHHHHHEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
AMP
CCC
>Mature Secondary Structure 
TRQIVLDTETTGLSAEGGDRIIELGCVELLNRKLTGNNLHLYFNPERDSHEDALKVHGI
CCEEEEECCCCCCCCCCCCEEEHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEECC
SNEFLKDKPKFAEVVDEILEYLQGAEIIIHNAAFDVGFLNKELELTGRPAFTSYVESVTD
CHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECEECEEECCCEEEECCCCHHHHHHHHHHH
TLVMAKEMYPGKRNSLDALCDRLGVDNSGRTLHGALLDAELLADVYINLTRGQDALLIAD
HHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHEEEECCCCEEEEEC
DAQEGDETAVRLAPVDLSAFTLPVLLASEQELAAHDEVLAQIDKASGGKTIWKISSDGQK
CCCCCCCCEEEEEECCCHHHHHHHEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
AMP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]