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The map label for this gene is tcp [H]

Identifier: 120611107

GI number: 120611107

Start: 2657792

End: 2659411

Strand: Reverse

Name: tcp [H]

Synonym: Aave_2436

Alternate gene names: 120611107

Gene position: 2659411-2657792 (Counterclockwise)

Preceding gene: 120611109

Following gene: 120611105

Centisome position: 49.68

GC content: 66.42

Gene sequence:

>1620_bases
ATGCGCAAAGCCACAATGAAAGTCAAGAACCAACTCGGCATCGCGTTCGGGGCCCTGGTGGTCATGGTGCTCATCGTTTC
GGTCATGTCCCTGCGTTCGCTGGGCAACGCGAACCAGAGTTTCACGGGATACGTGCAAGGCATCGACGCACAATCGAACA
TCGCGAACGATCTGCGCGAAGCCGTCAACCGCAGGGCGATCGCTGTACGCAATCTGGTGCTCGTCACGGAACGGCAAGAG
GTGGACAAGGAACTTGCGCTGGTGCTGCGAGCCGACGAGGATGTCCAGAAAGATCTGGCCGGGCTCAAGAAAATGGTCGC
GGCCGATTTCTCGGCCCCCGGATCGACGCGGCAACTGCTGGGCGAGCTGGAGCGGATCGAGGCGGTGTACGGCCCTGTGG
CCCGGGACATCGTGCGGATGGCCATGGCCGGACAGCGCGAGGCTGCCGTGACCAAGATCAACAATGAATGCCGTCCTCTG
CTGGCACAGCTCACGGGAAAGGCCGGAGATTTCGTCGCCGACGCCGGAAAGCGCGCCGTGGCCGCGGAAGATGAAGCCGG
CGAGAGCTTCGCCCAACAGCGCAACACCCTGCTCGCGGCCTGCCTGGTGGCGCTGGCCCTGGCCGTCGCCTCGGCAGTGA
CCATCACGCGCCGCCTGGCACGCGCACTGGGCGCAGAGCCTTCGGAACTGGGCTGGGCCGCCCAGCGGGTGGCCCAGGGC
GATCTGGTCCCGCTGGACGGAGCCGGCGGCGTGGCGGCGGGCAGCGTGATGGCCTCCCTGGCCACGATGCAAAGCAGCCT
GGCGCGCATTGCCACCCAGGTGCGCAGCGCGTCGGATTCCATCGCCATCGGCTCGGCGGAGATCGCCACGGGGGCCAGCG
ACCTGAGCATGCGCACAGAACAGCAGGCCAGCGCGCTGCAGGAAACATCCGCGACCATGGAAGAACTCAGTTCCACCGTG
CACCACAACGCCGACAGCGCGCAGCAGGCCAACCAGCTGGCGCAAGGCGCCTCCGGGGTGGCACAACAGGGAGGAGAGGC
CGTGAACCAGGTCGTGAGCACGATGCGGGAAATCAACCAGAGCTCGCGGCGCATCTCCGACATCATCGGCGTCATCGACG
GCATCGCCTTCCAGACCAACATCCTCGCGTTGAATGCCGCGGTGGAGGCAGCCCGGGCGGGCGAACACGGTCGCGGCTTC
GCCGTCGTCGCCAGCGAGGTGCGCAGCCTGGCCCAGCGCAGTGCTCAGGCCGCGCAGGAAATCAAGAACCTCATCACCGA
CAGCGTGACGCAGGTGGAAGCCGGATCGGCCCTGGTGGACCGGGCCGGGCAGACCATGGAAGAAGTGGTGGCGTCGATCA
AGCGGGTGAGCGACATCGTGGGAGAGATCAGCGCCGCCAGCGTCGAGCAGAGCCACGGTGTGGCGCAAGTGGGCATCGCA
GTGAACCAGATGGACGAGGCCACTCAGCAGAACGCCGCGCTGGTCGAGCAAAGCTCGGCGGCTGCGAAAAGCCTGCAGCA
ACAGGCACAGGACCTCGTGCAGGCCGTCTCGATCTTCAAGCTGCAGCCGCAGCACGGGGCCCTGCCCCAGCCGATGCAGC
TCGCTGCGATCCAGGGATGA

Upstream 100 bases:

>100_bases
GTCAATCCAGTCCATAGAAATCATTTTTATCGATTAAAACAATAATTTATTACATTTTCTACTTCAACGGCGACCCCCAT
CTTCTACAGAGGCCCCCTCA

Downstream 100 bases:

>100_bases
CGCCCCGGGGGCGCCGCCCTGCGAAACCGTGAACGCCCCCGGAGCGAGGCGCCTGGCCCTTCACCACTCGCCCACGGCAC
GCACCCTCTGGTCGAGGTCC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MRKATMKVKNQLGIAFGALVVMVLIVSVMSLRSLGNANQSFTGYVQGIDAQSNIANDLREAVNRRAIAVRNLVLVTERQE
VDKELALVLRADEDVQKDLAGLKKMVAADFSAPGSTRQLLGELERIEAVYGPVARDIVRMAMAGQREAAVTKINNECRPL
LAQLTGKAGDFVADAGKRAVAAEDEAGESFAQQRNTLLAACLVALALAVASAVTITRRLARALGAEPSELGWAAQRVAQG
DLVPLDGAGGVAAGSVMASLATMQSSLARIATQVRSASDSIAIGSAEIATGASDLSMRTEQQASALQETSATMEELSSTV
HHNADSAQQANQLAQGASGVAQQGGEAVNQVVSTMREINQSSRRISDIIGVIDGIAFQTNILALNAAVEAARAGEHGRGF
AVVASEVRSLAQRSAQAAQEIKNLITDSVTQVEAGSALVDRAGQTMEEVVASIKRVSDIVGEISAASVEQSHGVAQVGIA
VNQMDEATQQNAALVEQSSAAAKSLQQQAQDLVQAVSIFKLQPQHGALPQPMQLAAIQG

Sequences:

>Translated_539_residues
MRKATMKVKNQLGIAFGALVVMVLIVSVMSLRSLGNANQSFTGYVQGIDAQSNIANDLREAVNRRAIAVRNLVLVTERQE
VDKELALVLRADEDVQKDLAGLKKMVAADFSAPGSTRQLLGELERIEAVYGPVARDIVRMAMAGQREAAVTKINNECRPL
LAQLTGKAGDFVADAGKRAVAAEDEAGESFAQQRNTLLAACLVALALAVASAVTITRRLARALGAEPSELGWAAQRVAQG
DLVPLDGAGGVAAGSVMASLATMQSSLARIATQVRSASDSIAIGSAEIATGASDLSMRTEQQASALQETSATMEELSSTV
HHNADSAQQANQLAQGASGVAQQGGEAVNQVVSTMREINQSSRRISDIIGVIDGIAFQTNILALNAAVEAARAGEHGRGF
AVVASEVRSLAQRSAQAAQEIKNLITDSVTQVEAGSALVDRAGQTMEEVVASIKRVSDIVGEISAASVEQSHGVAQVGIA
VNQMDEATQQNAALVEQSSAAAKSLQQQAQDLVQAVSIFKLQPQHGALPQPMQLAAIQG
>Mature_539_residues
MRKATMKVKNQLGIAFGALVVMVLIVSVMSLRSLGNANQSFTGYVQGIDAQSNIANDLREAVNRRAIAVRNLVLVTERQE
VDKELALVLRADEDVQKDLAGLKKMVAADFSAPGSTRQLLGELERIEAVYGPVARDIVRMAMAGQREAAVTKINNECRPL
LAQLTGKAGDFVADAGKRAVAAEDEAGESFAQQRNTLLAACLVALALAVASAVTITRRLARALGAEPSELGWAAQRVAQG
DLVPLDGAGGVAAGSVMASLATMQSSLARIATQVRSASDSIAIGSAEIATGASDLSMRTEQQASALQETSATMEELSSTV
HHNADSAQQANQLAQGASGVAQQGGEAVNQVVSTMREINQSSRRISDIIGVIDGIAFQTNILALNAAVEAARAGEHGRGF
AVVASEVRSLAQRSAQAAQEIKNLITDSVTQVEAGSALVDRAGQTMEEVVASIKRVSDIVGEISAASVEQSHGVAQVGIA
VNQMDEATQQNAALVEQSSAAAKSLQQQAQDLVQAVSIFKLQPQHGALPQPMQLAAIQG

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=308, Percent_Identity=57.7922077922078, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI2367378, Length=338, Percent_Identity=54.4378698224852, Blast_Score=298, Evalue=6e-82,
Organism=Escherichia coli, GI1788194, Length=346, Percent_Identity=50, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1787690, Length=404, Percent_Identity=45.049504950495, Blast_Score=275, Evalue=7e-75,
Organism=Escherichia coli, GI1789453, Length=247, Percent_Identity=44.9392712550607, Blast_Score=197, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 56167; Mature: 56167

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS00306 CASEIN_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKATMKVKNQLGIAFGALVVMVLIVSVMSLRSLGNANQSFTGYVQGIDAQSNIANDLRE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHH
AVNRRAIAVRNLVLVTERQEVDKELALVLRADEDVQKDLAGLKKMVAADFSAPGSTRQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
GELERIEAVYGPVARDIVRMAMAGQREAAVTKINNECRPLLAQLTGKAGDFVADAGKRAV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHCCCCCCHHHHCCCCCC
AAEDEAGESFAQQRNTLLAACLVALALAVASAVTITRRLARALGAEPSELGWAAQRVAQG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
DLVPLDGAGGVAAGSVMASLATMQSSLARIATQVRSASDSIAIGSAEIATGASDLSMRTE
CCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHCCCHHHHHHHH
QQASALQETSATMEELSSTVHHNADSAQQANQLAQGASGVAQQGGEAVNQVVSTMREINQ
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SSRRISDIIGVIDGIAFQTNILALNAAVEAARAGEHGRGFAVVASEVRSLAQRSAQAAQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IKNLITDSVTQVEAGSALVDRAGQTMEEVVASIKRVSDIVGEISAASVEQSHGVAQVGIA
HHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VNQMDEATQQNAALVEQSSAAAKSLQQQAQDLVQAVSIFKLQPQHGALPQPMQLAAIQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MRKATMKVKNQLGIAFGALVVMVLIVSVMSLRSLGNANQSFTGYVQGIDAQSNIANDLRE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHH
AVNRRAIAVRNLVLVTERQEVDKELALVLRADEDVQKDLAGLKKMVAADFSAPGSTRQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
GELERIEAVYGPVARDIVRMAMAGQREAAVTKINNECRPLLAQLTGKAGDFVADAGKRAV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHCCCCCCHHHHCCCCCC
AAEDEAGESFAQQRNTLLAACLVALALAVASAVTITRRLARALGAEPSELGWAAQRVAQG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
DLVPLDGAGGVAAGSVMASLATMQSSLARIATQVRSASDSIAIGSAEIATGASDLSMRTE
CCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHCCCHHHHHHHH
QQASALQETSATMEELSSTVHHNADSAQQANQLAQGASGVAQQGGEAVNQVVSTMREINQ
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SSRRISDIIGVIDGIAFQTNILALNAAVEAARAGEHGRGFAVVASEVRSLAQRSAQAAQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IKNLITDSVTQVEAGSALVDRAGQTMEEVVASIKRVSDIVGEISAASVEQSHGVAQVGIA
HHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VNQMDEATQQNAALVEQSSAAAKSLQQQAQDLVQAVSIFKLQPQHGALPQPMQLAAIQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]