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The map label for this gene is dsdA

Identifier: 120611099

GI number: 120611099

Start: 2649271

End: 2650410

Strand: Direct

Name: dsdA

Synonym: Aave_2428

Alternate gene names: 120611099

Gene position: 2649271-2650410 (Clockwise)

Preceding gene: 120611098

Following gene: 120611100

Centisome position: 49.49

GC content: 71.67

Gene sequence:

>1140_bases
ATGCTCCGCACGGGCGGGGGCATCGAGTCACCACTGATCGAGGCAGGCGCGCTCTCGGATGCCATGGGGCTGGAGCCCGG
TTGCGGCCGGCTGTGGATCAAGGCGGACCACGGCCTTCCCGTGGCAGGCTCGATCAAGGCGCGCGGTGGCATCCACGAGG
TGCTGGAATTCGCGGAAACCCTGGCCGTGCGTGAAGGGCTGCTGTCCCCCGGACAGGATTGCCGGGTGCTGGCCGAGCCC
GCCGCGCGCGAGGTATTCGGACGCCACCAGGTGGCGGTGGGCTCCACGGGCAACCTGGGCCTGAGCATCGGCGTGGCGGC
CTCGGCGCTGGGCTTCCGTGCGGCGGTGCACATGTCCGCCGACGCCAAGGAGTGGAAGAAGGAGCGCCTGCGCCGCCGGG
GTGTCGAGGTGGTGGAGCATGCGGGCGACTACGAGCGCGCCGTGGCTGCGGGGCGCAGCCAGGCGCAGGCCGACCCGTTC
AGCCATTTCGTGGACGACGAACGCTCCCTTTCGCTGCTGCTGGGGTACAGCGCCGCGGCCCTGCACCTGCGCGGGCAACT
GGCGGAGCAGGGCATCGTGGTGGATGCCAAACATCCGCTGTTCGTCTATCTGCCTTGCGGGGTGGGGGGGGCGCCGGCCG
GTATCACCTTCGGGCTGCGCCAACTGCTCGGCCCCCACGTGCACTGCTTCTTCGCGGAGCCCGTGCAGTCGCCGTGCTTT
CTCGTGCAGATGGCCGCGCCGGCCGGCACGCATCCGTCCGTGTACGACCTGGGCCTGACCAACCGTACCGAAGCCGACGG
CCTCGCCGTGCCGAGGGCGTCGCTGCTGGCGGCAGGGCTGATGCAGCCCCTGCTGTCGGGCATCTTCACCGTCCGCGACG
ACACGTTGTTCGAGCACCTCGTGCGGGTGCTGGATGCCACGGGCGAGCGTATCGAGCCCTCCGCCGCGGCGGGGTTCAGC
GGGCCGGCCCTCCTCACGGGGTCGGACGGCGGCCGCCTTTGGCTGCGGGCGCAGGGCCTGGACGTCCAGCTACCCCAGGC
CACGCATCTCGTCTGGACCACGGGCGGGCTCTTCGTGCCCGAGGCCGAGCATCAGCGTTTCGAGGCCCGCGGCCGGTCTC
TGCTGGAGGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
GTCACGCTCAACCCTGAGCGCGACGGCATCTCCAATGCCGCGGCGACCGCATCGAATACGCAGCCTCGGGCTGCTTGATC
GACGCGACAACTACCTTGAC

Downstream 100 bases:

>100_bases
CCGGCGCCCGCCATCCATCCGATCTTCCATTCAACCCCCGGAGAGAACACCATGAACCGCGCCAAGAGGATGCTGCTGTC
CACCATCGCCTGTTGCCTGG

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MLRTGGGIESPLIEAGALSDAMGLEPGCGRLWIKADHGLPVAGSIKARGGIHEVLEFAETLAVREGLLSPGQDCRVLAEP
AAREVFGRHQVAVGSTGNLGLSIGVAASALGFRAAVHMSADAKEWKKERLRRRGVEVVEHAGDYERAVAAGRSQAQADPF
SHFVDDERSLSLLLGYSAAALHLRGQLAEQGIVVDAKHPLFVYLPCGVGGAPAGITFGLRQLLGPHVHCFFAEPVQSPCF
LVQMAAPAGTHPSVYDLGLTNRTEADGLAVPRASLLAAGLMQPLLSGIFTVRDDTLFEHLVRVLDATGERIEPSAAAGFS
GPALLTGSDGGRLWLRAQGLDVQLPQATHLVWTTGGLFVPEAEHQRFEARGRSLLEAAA

Sequences:

>Translated_379_residues
MLRTGGGIESPLIEAGALSDAMGLEPGCGRLWIKADHGLPVAGSIKARGGIHEVLEFAETLAVREGLLSPGQDCRVLAEP
AAREVFGRHQVAVGSTGNLGLSIGVAASALGFRAAVHMSADAKEWKKERLRRRGVEVVEHAGDYERAVAAGRSQAQADPF
SHFVDDERSLSLLLGYSAAALHLRGQLAEQGIVVDAKHPLFVYLPCGVGGAPAGITFGLRQLLGPHVHCFFAEPVQSPCF
LVQMAAPAGTHPSVYDLGLTNRTEADGLAVPRASLLAAGLMQPLLSGIFTVRDDTLFEHLVRVLDATGERIEPSAAAGFS
GPALLTGSDGGRLWLRAQGLDVQLPQATHLVWTTGGLFVPEAEHQRFEARGRSLLEAAA
>Mature_379_residues
MLRTGGGIESPLIEAGALSDAMGLEPGCGRLWIKADHGLPVAGSIKARGGIHEVLEFAETLAVREGLLSPGQDCRVLAEP
AAREVFGRHQVAVGSTGNLGLSIGVAASALGFRAAVHMSADAKEWKKERLRRRGVEVVEHAGDYERAVAAGRSQAQADPF
SHFVDDERSLSLLLGYSAAALHLRGQLAEQGIVVDAKHPLFVYLPCGVGGAPAGITFGLRQLLGPHVHCFFAEPVQSPCF
LVQMAAPAGTHPSVYDLGLTNRTEADGLAVPRASLLAAGLMQPLLSGIFTVRDDTLFEHLVRVLDATGERIEPSAAAGFS
GPALLTGSDGGRLWLRAQGLDVQLPQATHLVWTTGGLFVPEAEHQRFEARGRSLLEAAA

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily

Homologues:

Organism=Escherichia coli, GI1788708, Length=373, Percent_Identity=49.0616621983914, Blast_Score=325, Evalue=2e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHD_ACIAC (A1TPW5)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_970777.1
- ProteinModelPortal:   A1TPW5
- STRING:   A1TPW5
- GeneID:   4666940
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_2428
- NMPDR:   fig|397945.5.peg.2074
- eggNOG:   COG3048
- HOGENOM:   HBG288722
- ProtClustDB:   PRK02991
- BioCyc:   AAVE397945:AAVE_2428-MONOMER
- HAMAP:   MF_01030
- InterPro:   IPR011780
- InterPro:   IPR001926
- PANTHER:   PTHR10314:SF9
- TIGRFAMs:   TIGR02035

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.18

Molecular weight: Translated: 39922; Mature: 39922

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTGGGIESPLIEAGALSDAMGLEPGCGRLWIKADHGLPVAGSIKARGGIHEVLEFAET
CCCCCCCCCCCHHHHCCCCHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
LAVREGLLSPGQDCRVLAEPAAREVFGRHQVAVGSTGNLGLSIGVAASALGFRAAVHMSA
HHHHHHCCCCCCCCEEECCHHHHHHHCCCEEEECCCCCCCEEHHHHHHHHHHHEEEECCC
DAKEWKKERLRRRGVEVVEHAGDYERAVAAGRSQAQADPFSHFVDDERSLSLLLGYSAAA
CHHHHHHHHHHHHCHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEECCCHHH
LHLRGQLAEQGIVVDAKHPLFVYLPCGVGGAPAGITFGLRQLLGPHVHCFFAEPVQSPCF
HHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEE
LVQMAAPAGTHPSVYDLGLTNRTEADGLAVPRASLLAAGLMQPLLSGIFTVRDDTLFEHL
EEEECCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCHHHHHHH
VRVLDATGERIEPSAAAGFSGPALLTGSDGGRLWLRAQGLDVQLPQATHLVWTTGGLFVP
HHHHHCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCEEECCCCEEEEEECCCEECC
EAEHQRFEARGRSLLEAAA
CHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLRTGGGIESPLIEAGALSDAMGLEPGCGRLWIKADHGLPVAGSIKARGGIHEVLEFAET
CCCCCCCCCCCHHHHCCCCHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
LAVREGLLSPGQDCRVLAEPAAREVFGRHQVAVGSTGNLGLSIGVAASALGFRAAVHMSA
HHHHHHCCCCCCCCEEECCHHHHHHHCCCEEEECCCCCCCEEHHHHHHHHHHHEEEECCC
DAKEWKKERLRRRGVEVVEHAGDYERAVAAGRSQAQADPFSHFVDDERSLSLLLGYSAAA
CHHHHHHHHHHHHCHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEECCCHHH
LHLRGQLAEQGIVVDAKHPLFVYLPCGVGGAPAGITFGLRQLLGPHVHCFFAEPVQSPCF
HHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEE
LVQMAAPAGTHPSVYDLGLTNRTEADGLAVPRASLLAAGLMQPLLSGIFTVRDDTLFEHL
EEEECCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCHHHHHHH
VRVLDATGERIEPSAAAGFSGPALLTGSDGGRLWLRAQGLDVQLPQATHLVWTTGGLFVP
HHHHHCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCEEECCCCEEEEEECCCEECC
EAEHQRFEARGRSLLEAAA
CHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA