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The map label for this gene is gbpR [H]

Identifier: 120610983

GI number: 120610983

Start: 2538827

End: 2539792

Strand: Reverse

Name: gbpR [H]

Synonym: Aave_2311

Alternate gene names: 120610983

Gene position: 2539792-2538827 (Counterclockwise)

Preceding gene: 120610986

Following gene: 120610982

Centisome position: 47.45

GC content: 71.74

Gene sequence:

>966_bases
ATGTCTCTTGAACACGTGGCCTGGGCACGCCGGCTGAAGATCCGGCACCTCGAATCCTTCCTCGTGCTGGACGAGGCCGG
CACGCTGACCGAGGCGGCCGCGCGCATGCACATGACGCAGTCGGCCATGTCGCACTGGCTGGCGGACCTGGAGGAACTGG
TGGGCATGCCCCTGGTCACGCGCGGGCGGCGCATCCAGCTCACGCCGGCCGGGGTCATCATGAAGCGGCTGGCCGTGGGC
GTGCTGGGCGACATCTCGCGCACGCAGCTCGAGCTGGGCGCGGTGGCCGCGGGCCGCAGCGCGCGCCTGCACATCGGCAG
CGTGTGGGCCGGCGTGGCACGCGGGGTGCCGCAGGCGCTGGCGCAGTTCCAGGCCCTGCACCCGTACATCTCGGTCACCG
TGTCGGAGAGTCCGTTCGGGAACCTGCTGGAGGGGCTGGAGAACCGGCAGCTGGACGTGGTGATCGGCTCGCTGGACGCG
CGCGCCTGGCAGGGGCGGCTGGAACACCGCGAGCTGTTCGAGGACAACGTCTGCCTGGTGGTGGGCCGCGCCAGCCGCTT
CTGGGATGCGCCCGGGCCCGTGCGCCTGGCCGACCTGCTGCAGGAGAACTGGATCATGCCGCCCAAGGGCACGCTGATGC
GCTCGCAGCTGGACACGGCCCTGCTCGACAGCGGTGCGTCCTGGCTGCTGCCCAAGGTGGAGACCGCCGCCATCACCACG
CTGCAGGCCCTGCTGCACCAGGGCGACTACGTGGGCGTGTGCTCCGGGGCCATGGCCGAGTACCAGGCCACGCTGGGCAA
CCTGCGGGTGCTGCCGCTGGACCGCGCCATCCCCTTCGGCCCGGTGGGCGTGGTCTGGAGCCGCGACCATGCCTCGGAGG
CCGTGCGGCTTTTCGTGGAGCACATCACCGAGGCCACCATGGCGAGCCCATCCGCAGCCAGTGCCCCAGCCGGTCGGGAC
CGCTGA

Upstream 100 bases:

>100_bases
GCGTGCAGCCGTGCCCATGCCGGCCTTCCTGGAGCGATTATTCGGAGGTGCATGCCCCGGGACCAGCGAATTCGCCCGAT
GGATCCATTAGCATTTACTC

Downstream 100 bases:

>100_bases
AGCCCACGCAGGATCAAGCCGCTGCGCCGTCCCGGCGCAGCAAGCTGCGCGCGGCCTCGGCCACGCTGGCCGCATCCACG
CCGAAGTAGCTGCGCAGCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSLEHVAWARRLKIRHLESFLVLDEAGTLTEAAARMHMTQSAMSHWLADLEELVGMPLVTRGRRIQLTPAGVIMKRLAVG
VLGDISRTQLELGAVAAGRSARLHIGSVWAGVARGVPQALAQFQALHPYISVTVSESPFGNLLEGLENRQLDVVIGSLDA
RAWQGRLEHRELFEDNVCLVVGRASRFWDAPGPVRLADLLQENWIMPPKGTLMRSQLDTALLDSGASWLLPKVETAAITT
LQALLHQGDYVGVCSGAMAEYQATLGNLRVLPLDRAIPFGPVGVVWSRDHASEAVRLFVEHITEATMASPSAASAPAGRD
R

Sequences:

>Translated_321_residues
MSLEHVAWARRLKIRHLESFLVLDEAGTLTEAAARMHMTQSAMSHWLADLEELVGMPLVTRGRRIQLTPAGVIMKRLAVG
VLGDISRTQLELGAVAAGRSARLHIGSVWAGVARGVPQALAQFQALHPYISVTVSESPFGNLLEGLENRQLDVVIGSLDA
RAWQGRLEHRELFEDNVCLVVGRASRFWDAPGPVRLADLLQENWIMPPKGTLMRSQLDTALLDSGASWLLPKVETAAITT
LQALLHQGDYVGVCSGAMAEYQATLGNLRVLPLDRAIPFGPVGVVWSRDHASEAVRLFVEHITEATMASPSAASAPAGRD
R
>Mature_320_residues
SLEHVAWARRLKIRHLESFLVLDEAGTLTEAAARMHMTQSAMSHWLADLEELVGMPLVTRGRRIQLTPAGVIMKRLAVGV
LGDISRTQLELGAVAAGRSARLHIGSVWAGVARGVPQALAQFQALHPYISVTVSESPFGNLLEGLENRQLDVVIGSLDAR
AWQGRLEHRELFEDNVCLVVGRASRFWDAPGPVRLADLLQENWIMPPKGTLMRSQLDTALLDSGASWLLPKVETAAITTL
QALLHQGDYVGVCSGAMAEYQATLGNLRVLPLDRAIPFGPVGVVWSRDHASEAVRLFVEHITEATMASPSAASAPAGRDR

Specific function: Does not seem to be required for sbpA expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789506, Length=279, Percent_Identity=24.0143369175627, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87081904, Length=255, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790262, Length=172, Percent_Identity=30.2325581395349, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787806, Length=161, Percent_Identity=30.4347826086957, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787601, Length=288, Percent_Identity=23.6111111111111, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI157672245, Length=261, Percent_Identity=26.4367816091954, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788887, Length=171, Percent_Identity=25.7309941520468, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1788297, Length=247, Percent_Identity=27.5303643724696, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34878; Mature: 34746

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEHVAWARRLKIRHLESFLVLDEAGTLTEAAARMHMTQSAMSHWLADLEELVGMPLVT
CCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEC
RGRRIQLTPAGVIMKRLAVGVLGDISRTQLELGAVAAGRSARLHIGSVWAGVARGVPQAL
CCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCHHHHH
AQFQALHPYISVTVSESPFGNLLEGLENRQLDVVIGSLDARAWQGRLEHRELFEDNVCLV
HHHHHHCCEEEEEECCCCHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCCCEEEE
VGRASRFWDAPGPVRLADLLQENWIMPPKGTLMRSQLDTALLDSGASWLLPKVETAAITT
EECCHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LQALLHQGDYVGVCSGAMAEYQATLGNLRVLPLDRAIPFGPVGVVWSRDHASEAVRLFVE
HHHHHHCCCEEEECCCHHHHHHHHHCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHH
HITEATMASPSAASAPAGRDR
HHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLEHVAWARRLKIRHLESFLVLDEAGTLTEAAARMHMTQSAMSHWLADLEELVGMPLVT
CCHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEC
RGRRIQLTPAGVIMKRLAVGVLGDISRTQLELGAVAAGRSARLHIGSVWAGVARGVPQAL
CCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCHHHHH
AQFQALHPYISVTVSESPFGNLLEGLENRQLDVVIGSLDARAWQGRLEHRELFEDNVCLV
HHHHHHCCEEEEEECCCCHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHCCCEEEE
VGRASRFWDAPGPVRLADLLQENWIMPPKGTLMRSQLDTALLDSGASWLLPKVETAAITT
EECCHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LQALLHQGDYVGVCSGAMAEYQATLGNLRVLPLDRAIPFGPVGVVWSRDHASEAVRLFVE
HHHHHHCCCEEEECCCHHHHHHHHHCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHH
HITEATMASPSAASAPAGRDR
HHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]