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The map label for this gene is kdgR [H]

Identifier: 120610946

GI number: 120610946

Start: 2502522

End: 2503292

Strand: Direct

Name: kdgR [H]

Synonym: Aave_2272

Alternate gene names: 120610946

Gene position: 2502522-2503292 (Clockwise)

Preceding gene: 120610944

Following gene: 120610950

Centisome position: 46.75

GC content: 70.17

Gene sequence:

>771_bases
ATGACAGAAGACACCGATCGCTACCGCGCTCCCGCCCTGGACAAGGGGCTGGACATCCTCGAGCTGCTGGCCGGCCAGCC
CCATGGCCTCACCCGCGCCGAGATCGTCAAGGCCATGGGCCGCAGTCCGGGCGAGATCTACCGCATGCTCGAGAGGCTGG
TGGCGCGCGACTACGTCACCCGCTCGCCCCAGGGCGACCGCTACGCGCTCAGCCTCAAGCTCTTCGTGCTGGGGCACAGC
CATCCGCCCATGGAACGCATGGTGTCGCAGGCCTTGCCGTTCATGGAAGGCTTCGCCACCGCGGCGCAGCAGTCCTGCCA
TCTGGGCATTTACAACCGGGGGGGAATCACGGTGGTTGCCCAGGTCAACGGCCCGGGCAACTGGGGCCTGTCGATCCGCC
TGGGCGTGCGGGTGAGCCTGATCGACACGGCCTCGGGGCACGTGATGCTGGCCTTCCAGACCGAAGAGCGGCGTGCCGAG
ATGCTGGCCGAGCACCAGGCGCAGCAGGGCGTGCAGGGCGACGGGCCCATGCAGCCTGCGGAGCTGCAGACCATCCTGGA
GCGCATCCGCGCCCAGGGCTTCTGGCAGGGGGCCAGCCAGCAAGCCTTCGGCGTGACCGATATTTGCGTGCCCGTGCGGG
GGCCGCAGGGCCAGGCGCTGGCCGTGCTGACCTGCCCCTTCATCCAGCGCCCGGACCGGCCGCTGGAGGCCGATCTGCAA
GCCGCGCTCGATCAGCTGGCGCAGGCGGCGGGCGCCCTGTCGATCCGCTGA

Upstream 100 bases:

>100_bases
AAATTGCCAGGCACGTCGCCGCGCGATTGCCTGGAGAATGCGCACCGGCGCGCCCCCGGGGCCCTTCCGGCACAGGCCTT
CCCATCCCCCCTTCCCCGAA

Downstream 100 bases:

>100_bases
ACGGACCGTCCGGCCGGAACCTGTTCAATGTCTTCGTGGGGGCGCATGCACGGCGCCTGGTGGCCCGGAATGCCGGGCAA
CGGGTGCCTGCGGATCCCCC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTEDTDRYRAPALDKGLDILELLAGQPHGLTRAEIVKAMGRSPGEIYRMLERLVARDYVTRSPQGDRYALSLKLFVLGHS
HPPMERMVSQALPFMEGFATAAQQSCHLGIYNRGGITVVAQVNGPGNWGLSIRLGVRVSLIDTASGHVMLAFQTEERRAE
MLAEHQAQQGVQGDGPMQPAELQTILERIRAQGFWQGASQQAFGVTDICVPVRGPQGQALAVLTCPFIQRPDRPLEADLQ
AALDQLAQAAGALSIR

Sequences:

>Translated_256_residues
MTEDTDRYRAPALDKGLDILELLAGQPHGLTRAEIVKAMGRSPGEIYRMLERLVARDYVTRSPQGDRYALSLKLFVLGHS
HPPMERMVSQALPFMEGFATAAQQSCHLGIYNRGGITVVAQVNGPGNWGLSIRLGVRVSLIDTASGHVMLAFQTEERRAE
MLAEHQAQQGVQGDGPMQPAELQTILERIRAQGFWQGASQQAFGVTDICVPVRGPQGQALAVLTCPFIQRPDRPLEADLQ
AALDQLAQAAGALSIR
>Mature_255_residues
TEDTDRYRAPALDKGLDILELLAGQPHGLTRAEIVKAMGRSPGEIYRMLERLVARDYVTRSPQGDRYALSLKLFVLGHSH
PPMERMVSQALPFMEGFATAAQQSCHLGIYNRGGITVVAQVNGPGNWGLSIRLGVRVSLIDTASGHVMLAFQTEERRAEM
LAEHQAQQGVQGDGPMQPAELQTILERIRAQGFWQGASQQAFGVTDICVPVRGPQGQALAVLTCPFIQRPDRPLEADLQA
ALDQLAQAAGALSIR

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=241, Percent_Identity=26.1410788381743, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786468, Length=244, Percent_Identity=26.2295081967213, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27890; Mature: 27759

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEDTDRYRAPALDKGLDILELLAGQPHGLTRAEIVKAMGRSPGEIYRMLERLVARDYVT
CCCCCCHHCCCCHHCCHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RSPQGDRYALSLKLFVLGHSHPPMERMVSQALPFMEGFATAAQQSCHLGIYNRGGITVVA
CCCCCCEEEEEEEEEEEECCCCCHHHHHHHHCHHHHHHHHHHHCCCEEEEEECCCEEEEE
QVNGPGNWGLSIRLGVRVSLIDTASGHVMLAFQTEERRAEMLAEHQAQQGVQGDGPMQPA
EECCCCCCCEEEEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCHH
ELQTILERIRAQGFWQGASQQAFGVTDICVPVRGPQGQALAVLTCPFIQRPDRPLEADLQ
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECHHHCCCCCCCHHHHH
AALDQLAQAAGALSIR
HHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TEDTDRYRAPALDKGLDILELLAGQPHGLTRAEIVKAMGRSPGEIYRMLERLVARDYVT
CCCCCHHCCCCHHCCHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RSPQGDRYALSLKLFVLGHSHPPMERMVSQALPFMEGFATAAQQSCHLGIYNRGGITVVA
CCCCCCEEEEEEEEEEEECCCCCHHHHHHHHCHHHHHHHHHHHCCCEEEEEECCCEEEEE
QVNGPGNWGLSIRLGVRVSLIDTASGHVMLAFQTEERRAEMLAEHQAQQGVQGDGPMQPA
EECCCCCCCEEEEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCHH
ELQTILERIRAQGFWQGASQQAFGVTDICVPVRGPQGQALAVLTCPFIQRPDRPLEADLQ
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECHHHCCCCCCCHHHHH
AALDQLAQAAGALSIR
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]