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The map label for this gene is resD [H]

Identifier: 120610912

GI number: 120610912

Start: 2459203

End: 2459625

Strand: Reverse

Name: resD [H]

Synonym: Aave_2238

Alternate gene names: 120610912

Gene position: 2459625-2459203 (Counterclockwise)

Preceding gene: 120610916

Following gene: 120610911

Centisome position: 45.95

GC content: 68.56

Gene sequence:

>423_bases
ATGATTCAATCTTCGCAAGTGATTGCGCGCCCACCCATGAAGACCGTACTCATCGTTGACGACCATGCAGAGATCCGCCG
CCTTCTGCGCATGACGCTGGAAGACCAGGGGGTGGCCCTGCACGAGGCCGCGAGCGGCGAAGCCGCCCTGGCGATGGCGC
GCGCGCAGCGGCCCGACCTGGTGCTGCTGGATCTGATGATGCCCGGTTCGCTCGACGGAATGGAGGTCTGCCGGCGCATC
CGCAACGATCCGGACCTCTCCCACACCCGCGTCATCATTCTGAGCGCGCGCGACGGCCTGCAGGACCGCGCCGCGGGCAT
GCAGGCCGGTGCGAGCGGCTTCATTTCCAAGCCCTTCAGCCCCGCCTACCTCGCCGAGACCGTGCGGCGCCTCGACACCG
CCGGGACCCCGGTGGCCGGCTGA

Upstream 100 bases:

>100_bases
TTCGGCATAGCTGGCATTGTGCCTCTGTGCGGCGTGCAAGATGTATGCAGTGTGTGTCTGTCGGAATGCATTTCTCTTGC
AAACATGAAATCTAATAAAT

Downstream 100 bases:

>100_bases
TGCGGCGCATCCTGCCCGGCATGGGCTGCCCGGCGGCCTTGCTGCTGGCCGCCGCCCTGGCGGCGGCGCCATCGGCCCTG
CTCGCCGGGCCGGTCGCCGA

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MIQSSQVIARPPMKTVLIVDDHAEIRRLLRMTLEDQGVALHEAASGEAALAMARAQRPDLVLLDLMMPGSLDGMEVCRRI
RNDPDLSHTRVIILSARDGLQDRAAGMQAGASGFISKPFSPAYLAETVRRLDTAGTPVAG

Sequences:

>Translated_140_residues
MIQSSQVIARPPMKTVLIVDDHAEIRRLLRMTLEDQGVALHEAASGEAALAMARAQRPDLVLLDLMMPGSLDGMEVCRRI
RNDPDLSHTRVIILSARDGLQDRAAGMQAGASGFISKPFSPAYLAETVRRLDTAGTPVAG
>Mature_140_residues
MIQSSQVIARPPMKTVLIVDDHAEIRRLLRMTLEDQGVALHEAASGEAALAMARAQRPDLVLLDLMMPGSLDGMEVCRRI
RNDPDLSHTRVIILSARDGLQDRAAGMQAGASGFISKPFSPAYLAETVRRLDTAGTPVAG

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=117, Percent_Identity=41.025641025641, Blast_Score=78, Evalue=2e-16,
Organism=Escherichia coli, GI1786599, Length=126, Percent_Identity=31.7460317460317, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1789809, Length=115, Percent_Identity=33.9130434782609, Blast_Score=70, Evalue=6e-14,
Organism=Escherichia coli, GI1788191, Length=117, Percent_Identity=35.042735042735, Blast_Score=69, Evalue=8e-14,
Organism=Escherichia coli, GI1788394, Length=118, Percent_Identity=36.4406779661017, Blast_Score=69, Evalue=1e-13,
Organism=Escherichia coli, GI1788222, Length=130, Percent_Identity=35.3846153846154, Blast_Score=67, Evalue=6e-13,
Organism=Escherichia coli, GI87082012, Length=114, Percent_Identity=30.7017543859649, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1790860, Length=119, Percent_Identity=35.2941176470588, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1787375, Length=105, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=32.1739130434783, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 15103; Mature: 15103

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQSSQVIARPPMKTVLIVDDHAEIRRLLRMTLEDQGVALHEAASGEAALAMARAQRPDL
CCCCCCEEECCCCEEEEEEECHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCE
VLLDLMMPGSLDGMEVCRRIRNDPDLSHTRVIILSARDGLQDRAAGMQAGASGFISKPFS
EEEEEECCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCC
PAYLAETVRRLDTAGTPVAG
HHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIQSSQVIARPPMKTVLIVDDHAEIRRLLRMTLEDQGVALHEAASGEAALAMARAQRPDL
CCCCCCEEECCCCEEEEEEECHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCE
VLLDLMMPGSLDGMEVCRRIRNDPDLSHTRVIILSARDGLQDRAAGMQAGASGFISKPFS
EEEEEECCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCC
PAYLAETVRRLDTAGTPVAG
HHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]