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The map label for this gene is yfdZ [C]

Identifier: 120610903

GI number: 120610903

Start: 2449501

End: 2450685

Strand: Reverse

Name: yfdZ [C]

Synonym: Aave_2229

Alternate gene names: 120610903

Gene position: 2450685-2449501 (Counterclockwise)

Preceding gene: 120610904

Following gene: 120610902

Centisome position: 45.78

GC content: 71.39

Gene sequence:

>1185_bases
ATGAAGTTCTCCCGGCGCGCCGAGCGCATCGAACCCTTTTACGTGATGGAGATCGCCAAGGCCGCGCAGGCCCTGGCCCG
CGAGGTGGCCGGCGGCCCGGAACCGATGATCTTCCTGAACATCGGCGAGCCCGACTTCACCGCGCCGCCGCTGGTGCGCG
AGGCCGCCGACCGCGCCCTGCGCAGCGGCGCCACCCAGTACACCAATGCCCTCGGCCTGGAAGCGCTGCGCGAACGCATC
AGCGGCTGGTACGCCGAACGCTTCGGCGTGGCGGTGCCGGCGCGCCGCATCGTGGTCACGGCGGGCGCCTCCGGCGCCCT
GCAACTCGCCTGCCTGGCGCTCATCGAGCAGGGGGACGAGGTCCTCATGCCGGACCCGAGCTATCCGTGCAACCGCCATT
TCGTGAGCGCGGCGGACGGCCGCGCGGTGCTCGTCCCCTCCACCGCCGAAGAGCGCTTCCAGCTCAGCGCCGACAAGGTC
GCCGCGCACTGGGGCCCGAAGACGCGCGGCGTGCTGCTGGCCTCGCCCTCCAACCCCACGGGCACCTCGATCGCGCCCGG
CGAACTGCGCCGCATCCATGCCGCCGTGCAGGCGCGCGGCGGCTTCACCCTCATCGACGAGATCTACCTCGGCCTCTCCT
ACGAAGAGGCCTTCGGGCACACGGCGCTCGCGATCGGCGAGGACATCGTCAGCATCAACAGCTTCAGCAAATACTTCAAC
ATGACGGGCTGGCGCCTGGGCTGGATGGTCGTGCCCGAGGCCATGGTCCCGGTCGTGGAGCGGCTGGCGCAGAACCTCTT
CATCTGCCCGAGCACGGTGGCGCAGCATGCCGCGCTGGCCTGCTTCGAGCCGGACAGCATCGCCGAGTACGAACGCCGCC
GCGCCGAGTTCAAGGCCCGCCGCGACTACTTCATCCCCGCGCTCGAATCCCTGGGCCTGTCCGTGCCCGTGCGGCCGGAC
GGCGCCTTCTACGCCTGGGCCGACTGCACCACCGCCGCCCGGCGCCTGGGCGTGGAGGGCAGCTGGAACTTCGCCCACGA
GGTGATGCGCCGCGCCCACCTGGCCCTCACGCCGGGGCGCGACTTCGGCAGCCACGCCCCCGAGGCCTTCGTGCGCTTTT
CCACGGCCAACTCCATGGCGCAGCTGCAGGAAGCCGTGGCACGGCTGTCCCGGCTGCTGGCCTGA

Upstream 100 bases:

>100_bases
GCCCGGGCCGCGCGCCCCCCTCTTTCGCCCGCCCCCCGGCTGCCGCCCGGCTCCCACGGGAGCTGCGCGGCGCCCCAGCC
CCCTTTCGGACATCCCTCCC

Downstream 100 bases:

>100_bases
CGCGCGGCGCGAGGCACGCCCCATGAGCTTCGGATGGCCCGTGCGCATCTACTGGGAAGACACGGATGCCGGCGGCATCG
TCTTCTACGCCAACTACCTG

Product: aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKFSRRAERIEPFYVMEIAKAAQALAREVAGGPEPMIFLNIGEPDFTAPPLVREAADRALRSGATQYTNALGLEALRERI
SGWYAERFGVAVPARRIVVTAGASGALQLACLALIEQGDEVLMPDPSYPCNRHFVSAADGRAVLVPSTAEERFQLSADKV
AAHWGPKTRGVLLASPSNPTGTSIAPGELRRIHAAVQARGGFTLIDEIYLGLSYEEAFGHTALAIGEDIVSINSFSKYFN
MTGWRLGWMVVPEAMVPVVERLAQNLFICPSTVAQHAALACFEPDSIAEYERRRAEFKARRDYFIPALESLGLSVPVRPD
GAFYAWADCTTAARRLGVEGSWNFAHEVMRRAHLALTPGRDFGSHAPEAFVRFSTANSMAQLQEAVARLSRLLA

Sequences:

>Translated_394_residues
MKFSRRAERIEPFYVMEIAKAAQALAREVAGGPEPMIFLNIGEPDFTAPPLVREAADRALRSGATQYTNALGLEALRERI
SGWYAERFGVAVPARRIVVTAGASGALQLACLALIEQGDEVLMPDPSYPCNRHFVSAADGRAVLVPSTAEERFQLSADKV
AAHWGPKTRGVLLASPSNPTGTSIAPGELRRIHAAVQARGGFTLIDEIYLGLSYEEAFGHTALAIGEDIVSINSFSKYFN
MTGWRLGWMVVPEAMVPVVERLAQNLFICPSTVAQHAALACFEPDSIAEYERRRAEFKARRDYFIPALESLGLSVPVRPD
GAFYAWADCTTAARRLGVEGSWNFAHEVMRRAHLALTPGRDFGSHAPEAFVRFSTANSMAQLQEAVARLSRLLA
>Mature_394_residues
MKFSRRAERIEPFYVMEIAKAAQALAREVAGGPEPMIFLNIGEPDFTAPPLVREAADRALRSGATQYTNALGLEALRERI
SGWYAERFGVAVPARRIVVTAGASGALQLACLALIEQGDEVLMPDPSYPCNRHFVSAADGRAVLVPSTAEERFQLSADKV
AAHWGPKTRGVLLASPSNPTGTSIAPGELRRIHAAVQARGGFTLIDEIYLGLSYEEAFGHTALAIGEDIVSINSFSKYFN
MTGWRLGWMVVPEAMVPVVERLAQNLFICPSTVAQHAALACFEPDSIAEYERRRAEFKARRDYFIPALESLGLSVPVRPD
GAFYAWADCTTAARRLGVEGSWNFAHEVMRRAHLALTPGRDFGSHAPEAFVRFSTANSMAQLQEAVARLSRLLA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=392, Percent_Identity=26.7857142857143, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI169881279, Length=392, Percent_Identity=26.7857142857143, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI56713254, Length=381, Percent_Identity=26.246719160105, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI56713256, Length=381, Percent_Identity=26.246719160105, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI4507369, Length=325, Percent_Identity=24.6153846153846, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI169881281, Length=305, Percent_Identity=24.5901639344262, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1788722, Length=394, Percent_Identity=27.9187817258883, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1788627, Length=378, Percent_Identity=27.5132275132275, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786816, Length=365, Percent_Identity=28.2191780821918, Blast_Score=115, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=356, Percent_Identity=26.4044943820225, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=356, Percent_Identity=26.4044943820225, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=383, Percent_Identity=25.3263707571802, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17567663, Length=395, Percent_Identity=25.3164556962025, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322401, Length=386, Percent_Identity=22.5388601036269, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28573069, Length=392, Percent_Identity=26.0204081632653, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646114, Length=392, Percent_Identity=26.0204081632653, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573067, Length=392, Percent_Identity=26.0204081632653, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573065, Length=392, Percent_Identity=26.0204081632653, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18859735, Length=389, Percent_Identity=22.107969151671, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43022; Mature: 43022

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSRRAERIEPFYVMEIAKAAQALAREVAGGPEPMIFLNIGEPDFTAPPLVREAADRAL
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
RSGATQYTNALGLEALRERISGWYAERFGVAVPARRIVVTAGASGALQLACLALIEQGDE
HCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCE
VLMPDPSYPCNRHFVSAADGRAVLVPSTAEERFQLSADKVAAHWGPKTRGVLLASPSNPT
EECCCCCCCCCCCEEECCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
GTSIAPGELRRIHAAVQARGGFTLIDEIYLGLSYEEAFGHTALAIGEDIVSINSFSKYFN
CCCCCCHHHHHHHHHHHCCCCEEEHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHC
MTGWRLGWMVVPEAMVPVVERLAQNLFICPSTVAQHAALACFEPDSIAEYERRRAEFKAR
CCCCEEEEEECCHHHHHHHHHHHHHEEECCHHHHHHHHEEEECCHHHHHHHHHHHHHHHH
RDYFIPALESLGLSVPVRPDGAFYAWADCTTAARRLGVEGSWNFAHEVMRRAHLALTPGR
HHHHHHHHHHCCCEEEECCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHEECCCC
DFGSHAPEAFVRFSTANSMAQLQEAVARLSRLLA
CCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFSRRAERIEPFYVMEIAKAAQALAREVAGGPEPMIFLNIGEPDFTAPPLVREAADRAL
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
RSGATQYTNALGLEALRERISGWYAERFGVAVPARRIVVTAGASGALQLACLALIEQGDE
HCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCE
VLMPDPSYPCNRHFVSAADGRAVLVPSTAEERFQLSADKVAAHWGPKTRGVLLASPSNPT
EECCCCCCCCCCCEEECCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
GTSIAPGELRRIHAAVQARGGFTLIDEIYLGLSYEEAFGHTALAIGEDIVSINSFSKYFN
CCCCCCHHHHHHHHHHHCCCCEEEHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHC
MTGWRLGWMVVPEAMVPVVERLAQNLFICPSTVAQHAALACFEPDSIAEYERRRAEFKAR
CCCCEEEEEECCHHHHHHHHHHHHHEEECCHHHHHHHHEEEECCHHHHHHHHHHHHHHHH
RDYFIPALESLGLSVPVRPDGAFYAWADCTTAARRLGVEGSWNFAHEVMRRAHLALTPGR
HHHHHHHHHHCCCEEEECCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHEECCCC
DFGSHAPEAFVRFSTANSMAQLQEAVARLSRLLA
CCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]