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The map label for this gene is regB [H]

Identifier: 120610892

GI number: 120610892

Start: 2438628

End: 2439977

Strand: Reverse

Name: regB [H]

Synonym: Aave_2218

Alternate gene names: 120610892

Gene position: 2439977-2438628 (Counterclockwise)

Preceding gene: 120610893

Following gene: 120610891

Centisome position: 45.58

GC content: 70.22

Gene sequence:

>1350_bases
GTGCCCGGCGCGAAGCCTCCCCCGGCCGGGCCTGCCGCGCCTTCGGTGCGCAATGCGCGCTACGCGAACGCGGCCGCGGG
CCTCAAGAATCTGCACCAGCTCATCCAGTTGCGCTGGGTGGCCGCCATCGGCCAGGTGTTCACCATCGAGGTCGCCTACT
ACAGCCTCGGGCTGACCCTGCCGGTGCGCGAGATGCTCATGGTCGTGGGCTGCCTGGTGCTCTTCAACCTCGTCAGTCTG
GTGCGCTGGCGCACCGGGCACGGCGTGCGGCAGGTGGAGCTGTTCCTGGCGCTGCTGATCGACGTGGCGGTGCTCACGGT
GCAGCTCTACCTGAGCGGCGGCACCGGCAATCCATTCGTCTTCCTCTACCTGCTGCAGATCGCGGTCGGCGCGGTGCTGC
TGCGCGGCGGCTACATCTGGTCGATCGTGGCGATCACCACCGGCTGCTTCGCGGCGCTTTCGCGCTTCAACCTGCCGCTG
CCCGTGCCCGCGGACCTGCACCGCGGCCTGTCCAGCCCGTACCTGCTGGGCCTGCTGGTGTGCTTCCTGCTCAACGCGAT
CCTGGTGGTCATCTTCATCACCCGCATCGAGCGCAACCTGCGCCAGCGCGATGCGCGGCTGGCGGCGGCGCGCCAGCGCG
CCATGGAGGAGGAGCACATCGTGCGCATGGGCCTGCTGGCCTCGGGCGCGGCCCACGAACTGGGCACGCCGCTGTCCACC
ATGGCCGTCATCCTGGGCGACTGGCGGCACGACGAGCGGCTGGCCGCCGACCGCATGCTGCAGGACGAGATCGAGGAAAT
GCAGGTCCAGGTGCAGCGCTGCAAGAGCATCGTGAGCGGCATCCTGCTGTCGGCCGGCGAAGCGCGCGGCGAAGCGTCCG
CGCAGACCACGGTGCGCACCTTCGTCGATGCGCTCGCGCGGGACTGGAGGGCCACGCGCGCCATCGCCGCATTCGACTAC
GACAACCGCTTCGGCGCCGACACGCCCATGGTGTCGGACACCATGCTGCAGCAGATGGTTTTCAATGTGTTGGACAATGC
GCGGGACGCCTCGCCCGACTGGGTGGGGATGGCCGTCGAGCGCGATGCCGACCTGCTGCGCATCACCGTGACCGATGCCG
GCCCCGGGTTCGAGCCGGCCATCCTTGCGCGGCTCGGCAAGCCCTACCAGTCGAGCAAGGGCCGCGCGGGGGGCGGGCTG
GGCCTGTTCCTGGCCATGAACGTGGCGCGCACCCTCGGCGGCAGCGTCACGGCCCGCAACCTGCCGGAGCGCGGCGCCGA
GGTCAGCATCCGGCTGCCGCTGTCGGCGGTCGCGCTGCCACCCACCGGACACATACACCATGGACGATGA

Upstream 100 bases:

>100_bases
GTGGCACGCTACGAGTTTCGTTCGCGCGCAGCCGACCGTGCCCTCCACCCCTCCGACCGCTCCACTCCCTGATTCCGGCC
CGGGCACAGCGCCTTCCGCG

Downstream 100 bases:

>100_bases
ACGCCTGCTGCTGATCGTGGAGGACGACGAAGCCCTCGCCAGGACACTGGCGCGCTCCTTCGAGCGCCGCGGCTACCGCG
TGCTGCATGCCGACAGCCTG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MPGAKPPPAGPAAPSVRNARYANAAAGLKNLHQLIQLRWVAAIGQVFTIEVAYYSLGLTLPVREMLMVVGCLVLFNLVSL
VRWRTGHGVRQVELFLALLIDVAVLTVQLYLSGGTGNPFVFLYLLQIAVGAVLLRGGYIWSIVAITTGCFAALSRFNLPL
PVPADLHRGLSSPYLLGLLVCFLLNAILVVIFITRIERNLRQRDARLAAARQRAMEEEHIVRMGLLASGAAHELGTPLST
MAVILGDWRHDERLAADRMLQDEIEEMQVQVQRCKSIVSGILLSAGEARGEASAQTTVRTFVDALARDWRATRAIAAFDY
DNRFGADTPMVSDTMLQQMVFNVLDNARDASPDWVGMAVERDADLLRITVTDAGPGFEPAILARLGKPYQSSKGRAGGGL
GLFLAMNVARTLGGSVTARNLPERGAEVSIRLPLSAVALPPTGHIHHGR

Sequences:

>Translated_449_residues
MPGAKPPPAGPAAPSVRNARYANAAAGLKNLHQLIQLRWVAAIGQVFTIEVAYYSLGLTLPVREMLMVVGCLVLFNLVSL
VRWRTGHGVRQVELFLALLIDVAVLTVQLYLSGGTGNPFVFLYLLQIAVGAVLLRGGYIWSIVAITTGCFAALSRFNLPL
PVPADLHRGLSSPYLLGLLVCFLLNAILVVIFITRIERNLRQRDARLAAARQRAMEEEHIVRMGLLASGAAHELGTPLST
MAVILGDWRHDERLAADRMLQDEIEEMQVQVQRCKSIVSGILLSAGEARGEASAQTTVRTFVDALARDWRATRAIAAFDY
DNRFGADTPMVSDTMLQQMVFNVLDNARDASPDWVGMAVERDADLLRITVTDAGPGFEPAILARLGKPYQSSKGRAGGGL
GLFLAMNVARTLGGSVTARNLPERGAEVSIRLPLSAVALPPTGHIHHGR
>Mature_448_residues
PGAKPPPAGPAAPSVRNARYANAAAGLKNLHQLIQLRWVAAIGQVFTIEVAYYSLGLTLPVREMLMVVGCLVLFNLVSLV
RWRTGHGVRQVELFLALLIDVAVLTVQLYLSGGTGNPFVFLYLLQIAVGAVLLRGGYIWSIVAITTGCFAALSRFNLPLP
VPADLHRGLSSPYLLGLLVCFLLNAILVVIFITRIERNLRQRDARLAAARQRAMEEEHIVRMGLLASGAAHELGTPLSTM
AVILGDWRHDERLAADRMLQDEIEEMQVQVQRCKSIVSGILLSAGEARGEASAQTTVRTFVDALARDWRATRAIAAFDYD
NRFGADTPMVSDTMLQQMVFNVLDNARDASPDWVGMAVERDADLLRITVTDAGPGFEPAILARLGKPYQSSKGRAGGGLG
LFLAMNVARTLGGSVTARNLPERGAEVSIRLPLSAVALPPTGHIHHGR

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=107, Percent_Identity=33.6448598130841, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48620; Mature: 48489

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGAKPPPAGPAAPSVRNARYANAAAGLKNLHQLIQLRWVAAIGQVFTIEVAYYSLGLTL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEHHHHHCCCH
PVREMLMVVGCLVLFNLVSLVRWRTGHGVRQVELFLALLIDVAVLTVQLYLSGGTGNPFV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHH
FLYLLQIAVGAVLLRGGYIWSIVAITTGCFAALSRFNLPLPVPADLHRGLSSPYLLGLLV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHH
CFLLNAILVVIFITRIERNLRQRDARLAAARQRAMEEEHIVRMGLLASGAAHELGTPLST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHH
MAVILGDWRHDERLAADRMLQDEIEEMQVQVQRCKSIVSGILLSAGEARGEASAQTTVRT
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
FVDALARDWRATRAIAAFDYDNRFGADTPMVSDTMLQQMVFNVLDNARDASPDWVGMAVE
HHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
RDADLLRITVTDAGPGFEPAILARLGKPYQSSKGRAGGGLGLFLAMNVARTLGGSVTARN
CCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECC
LPERGAEVSIRLPLSAVALPPTGHIHHGR
CCCCCCEEEEECCHHEEECCCCCCCCCCC
>Mature Secondary Structure 
PGAKPPPAGPAAPSVRNARYANAAAGLKNLHQLIQLRWVAAIGQVFTIEVAYYSLGLTL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEHHHHHCCCH
PVREMLMVVGCLVLFNLVSLVRWRTGHGVRQVELFLALLIDVAVLTVQLYLSGGTGNPFV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHH
FLYLLQIAVGAVLLRGGYIWSIVAITTGCFAALSRFNLPLPVPADLHRGLSSPYLLGLLV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHH
CFLLNAILVVIFITRIERNLRQRDARLAAARQRAMEEEHIVRMGLLASGAAHELGTPLST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHH
MAVILGDWRHDERLAADRMLQDEIEEMQVQVQRCKSIVSGILLSAGEARGEASAQTTVRT
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
FVDALARDWRATRAIAAFDYDNRFGADTPMVSDTMLQQMVFNVLDNARDASPDWVGMAVE
HHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
RDADLLRITVTDAGPGFEPAILARLGKPYQSSKGRAGGGLGLFLAMNVARTLGGSVTARN
CCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECC
LPERGAEVSIRLPLSAVALPPTGHIHHGR
CCCCCCEEEEECCHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]