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The map label for this gene is ilvY [H]

Identifier: 120610889

GI number: 120610889

Start: 2436194

End: 2437111

Strand: Reverse

Name: ilvY [H]

Synonym: Aave_2215

Alternate gene names: 120610889

Gene position: 2437111-2436194 (Counterclockwise)

Preceding gene: 120610891

Following gene: 120610888

Centisome position: 45.53

GC content: 77.56

Gene sequence:

>918_bases
ATGCGCTTCGACCTGACGGACCTGCGGCTCTTCCTCCACGTGCACGAGGCCGGCACGATCACGGCGGGCGCGGAGCGGGC
GCACCTGGCGCTGGCGTCGGCCAGCGAGCGCCTGCTCGCGATGGAGCAGGCGCTCGGCGCGCCGCTGCTGGTCCGGGGCC
GGCGCGGAGTGCGCGCCACCCCGGCCGGGCAGACGCTGGCGCACCATGCGCGCATCGTGCTGCAGCAGGTGGAGCAACTG
CGCGGCGAACTCGGCGCGCACGGCAGCGGCCTGGCCGGCCACGTGCGCCTGCTCTGCAACACCTCCGCCATGAGCGAACA
CCTGCCCGCGCCGCTGGCCGCCTTCCTGGCGGCGCATCCCCGCATCGCGGTGGACGCGCAGGAGCGCTCCAGCGACGGCG
TGGCCGATGGCGTGCGCGACGGCCTGTGCGACATCGGCATCGCCTCGCGCTCCGCCGACCTGCAGGGACTGGCAGTCCTG
CCTTTCGTGGCCGACCCGCTGGACCTCGTGGTGCACCGCGGCCATCCGCTGGCCGGCCGCGGCCGCATCGCGCTGGCGGA
CGCGGCGCAGGAGGACTTCACCGGCCTGCCGGACGACAGCGCGCTGCAGGCCCACCTCGCCCGCCAGGCGCGGCGCCAGG
GCCAGCGGCTGCGCTACCGCGCGCGCCTGCAGCATGTCGATGCGGTCTGCCGCCTCGTGGGGCTGGGCGCGGGCCTCGTG
GCCATCGTGCCGCGCGCGGCGGCGGTGCGCCTGGCCCGCTCCACCGGCATCCGGCGCGTGGCGCTGTCCGACGCCTGGGC
CGCGCGGGAGCTGGTGCTGTGCGTGCGCGCGGACGGCGGCGGAGCCCCGGACGCCCTGCCCCGGCATGCCCGCGCGCTGC
TGGACCACCTTGCCGGATGGCGCGGGGCCGGAGGCTGA

Upstream 100 bases:

>100_bases
AGCGATTCTGGAAGCGGCCGCCAACGGGCGCCATGCGGATGTTCCGTGGCCAGCCTTCGGATTTTCCGGAGCCAGAACGC
CACCTGTGTTAGCGTGCCGC

Downstream 100 bases:

>100_bases
GGACAAAAGCCTGCGCCAGGTCAAGGAGCGCGCCGCGGCCGGGCGCCACAATCGCGCGCTCCACCGCGCCCTGCCCTGCT
CCCATGACGCTCCGCCCGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MRFDLTDLRLFLHVHEAGTITAGAERAHLALASASERLLAMEQALGAPLLVRGRRGVRATPAGQTLAHHARIVLQQVEQL
RGELGAHGSGLAGHVRLLCNTSAMSEHLPAPLAAFLAAHPRIAVDAQERSSDGVADGVRDGLCDIGIASRSADLQGLAVL
PFVADPLDLVVHRGHPLAGRGRIALADAAQEDFTGLPDDSALQAHLARQARRQGQRLRYRARLQHVDAVCRLVGLGAGLV
AIVPRAAAVRLARSTGIRRVALSDAWAARELVLCVRADGGGAPDALPRHARALLDHLAGWRGAGG

Sequences:

>Translated_305_residues
MRFDLTDLRLFLHVHEAGTITAGAERAHLALASASERLLAMEQALGAPLLVRGRRGVRATPAGQTLAHHARIVLQQVEQL
RGELGAHGSGLAGHVRLLCNTSAMSEHLPAPLAAFLAAHPRIAVDAQERSSDGVADGVRDGLCDIGIASRSADLQGLAVL
PFVADPLDLVVHRGHPLAGRGRIALADAAQEDFTGLPDDSALQAHLARQARRQGQRLRYRARLQHVDAVCRLVGLGAGLV
AIVPRAAAVRLARSTGIRRVALSDAWAARELVLCVRADGGGAPDALPRHARALLDHLAGWRGAGG
>Mature_305_residues
MRFDLTDLRLFLHVHEAGTITAGAERAHLALASASERLLAMEQALGAPLLVRGRRGVRATPAGQTLAHHARIVLQQVEQL
RGELGAHGSGLAGHVRLLCNTSAMSEHLPAPLAAFLAAHPRIAVDAQERSSDGVADGVRDGLCDIGIASRSADLQGLAVL
PFVADPLDLVVHRGHPLAGRGRIALADAAQEDFTGLPDDSALQAHLARQARRQGQRLRYRARLQHVDAVCRLVGLGAGLV
AIVPRAAAVRLARSTGIRRVALSDAWAARELVLCVRADGGGAPDALPRHARALLDHLAGWRGAGG

Specific function: This protein activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate. IlvY is also a negative regulator of its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790208, Length=279, Percent_Identity=26.1648745519713, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI145693105, Length=242, Percent_Identity=22.3140495867769, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=273, Percent_Identity=26.007326007326, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787530, Length=242, Percent_Identity=26.0330578512397, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787879, Length=288, Percent_Identity=26.0416666666667, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787806, Length=172, Percent_Identity=27.3255813953488, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788297, Length=167, Percent_Identity=29.940119760479, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788748, Length=178, Percent_Identity=26.4044943820225, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790399, Length=201, Percent_Identity=23.3830845771144, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32108; Mature: 32108

Theoretical pI: Translated: 11.01; Mature: 11.01

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDLTDLRLFLHVHEAGTITAGAERAHLALASASERLLAMEQALGAPLLVRGRRGVRAT
CCCCHHHHEEEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
PAGQTLAHHARIVLQQVEQLRGELGAHGSGLAGHVRLLCNTSAMSEHLPAPLAAFLAAHP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHCCHHHHHHHHCCC
RIAVDAQERSSDGVADGVRDGLCDIGIASRSADLQGLAVLPFVADPLDLVVHRGHPLAGR
CEEEECHHCCCCCCHHHHHCCHHHCCCCCCCCCCCCEEECCHHCCHHHHHHCCCCCCCCC
GRIALADAAQEDFTGLPDDSALQAHLARQARRQGQRLRYRARLQHVDAVCRLVGLGAGLV
CCEEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AIVPRAAAVRLARSTGIRRVALSDAWAARELVLCVRADGGGAPDALPRHARALLDHLAGW
HHHHHHHHHHHHHHCCCEEEEHHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCC
RGAGG
CCCCC
>Mature Secondary Structure
MRFDLTDLRLFLHVHEAGTITAGAERAHLALASASERLLAMEQALGAPLLVRGRRGVRAT
CCCCHHHHEEEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
PAGQTLAHHARIVLQQVEQLRGELGAHGSGLAGHVRLLCNTSAMSEHLPAPLAAFLAAHP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHCCHHHHHHHHCCC
RIAVDAQERSSDGVADGVRDGLCDIGIASRSADLQGLAVLPFVADPLDLVVHRGHPLAGR
CEEEECHHCCCCCCHHHHHCCHHHCCCCCCCCCCCCEEECCHHCCHHHHHHCCCCCCCCC
GRIALADAAQEDFTGLPDDSALQAHLARQARRQGQRLRYRARLQHVDAVCRLVGLGAGLV
CCEEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AIVPRAAAVRLARSTGIRRVALSDAWAARELVLCVRADGGGAPDALPRHARALLDHLAGW
HHHHHHHHHHHHHHCCCEEEEHHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCC
RGAGG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]