Click here to switch to the map view.

The map label for this gene is frlR [H]

Identifier: 120610879

GI number: 120610879

Start: 2424724

End: 2425560

Strand: Reverse

Name: frlR [H]

Synonym: Aave_2205

Alternate gene names: 120610879

Gene position: 2425560-2424724 (Counterclockwise)

Preceding gene: 120610886

Following gene: 120610878

Centisome position: 45.31

GC content: 71.33

Gene sequence:

>837_bases
ATGATGCGGACCGCCGCACACGGCGCCCGAGCCCCCACGAACCGCATGTCCACCCCACCGGCAGCCACTCCCGACAGCCC
CGCCCCGACGGCCGGCGGCGCGGGTGCGCCGACGCCGGCATTCAGCCCGCTCTACCAGCAGATCAAGGGGCTCATCCTGC
AGAGCCTGCAGCAGGGCGAATGGAAGCCTGGCGAGGCCATCCCCAGTGAAATGGAGCTGGCGGCCCGCTTCCGCGTGAGC
CAGGGCACGGTGCGCAAGGCGATCGACGAGCTGGCGGCCGAGAACCTCGTGATGCGCCGCCAGGGCAAGGGCACCTTCGT
CGCCACCCATGCCGAGCGCCATGTGCAATACCGCTTCCTGAAGCTGCAGCCCGACGTGGGCGACCCGGACGCCGAAGGCC
CGGCCCAGCGCCGCATCGTGGAATGCCGGCGCACCCGCGCCAGCGCCGACGTGGCGCGCGCCCTGGCGCTGCGCGGCGGG
GACGCCGTGGTCATGGCCCGGCGCATCCTCTCGTTCGCGGGCGTGCCCACCATCCTGGAGGACATCTGGCTGCCCGGCCA
GACCTTCAAGGGCCTCACGGCCGAACGGCTGGCCGACTACCCCGGCCCCACCTATGCGATGTTCGAGCTCGACTTCGGCG
TGCGCATGGTGCGCGCCGACGAGAAGATCCGCGCGGTGCTGCCCGACGCGGCGCAGGCCGGGCTGCTGGGCGTTCCCGCC
GGCACGCCGCTGCTGAGCGTGGAGCGCACCGCCTATACCTACAACGATGTTCCGATGGAGTTACGCCGAGGGCTCTACCG
GACCGACACGCACCACTACCACAATGCACTGCAGTGA

Upstream 100 bases:

>100_bases
AGCGCCAGTCGATCCAAGCAGCCAGGGTCCTGCAGAACAGCTCCCGAGTGTACCGCCGATTTCCGGCGAGGGTCAATTTG
TCTTATGTCTTATATAAGAT

Downstream 100 bases:

>100_bases
ACCGGCAGTCCTCCCCGTGCGTATAGCCGCGGGATGGAAATCGTAGTACCCACAAACTCCGCCTTGTTGCATTGCAATAG
AATTTTGGGCGTTTCGCCCG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MMRTAAHGARAPTNRMSTPPAATPDSPAPTAGGAGAPTPAFSPLYQQIKGLILQSLQQGEWKPGEAIPSEMELAARFRVS
QGTVRKAIDELAAENLVMRRQGKGTFVATHAERHVQYRFLKLQPDVGDPDAEGPAQRRIVECRRTRASADVARALALRGG
DAVVMARRILSFAGVPTILEDIWLPGQTFKGLTAERLADYPGPTYAMFELDFGVRMVRADEKIRAVLPDAAQAGLLGVPA
GTPLLSVERTAYTYNDVPMELRRGLYRTDTHHYHNALQ

Sequences:

>Translated_278_residues
MMRTAAHGARAPTNRMSTPPAATPDSPAPTAGGAGAPTPAFSPLYQQIKGLILQSLQQGEWKPGEAIPSEMELAARFRVS
QGTVRKAIDELAAENLVMRRQGKGTFVATHAERHVQYRFLKLQPDVGDPDAEGPAQRRIVECRRTRASADVARALALRGG
DAVVMARRILSFAGVPTILEDIWLPGQTFKGLTAERLADYPGPTYAMFELDFGVRMVRADEKIRAVLPDAAQAGLLGVPA
GTPLLSVERTAYTYNDVPMELRRGLYRTDTHHYHNALQ
>Mature_278_residues
MMRTAAHGARAPTNRMSTPPAATPDSPAPTAGGAGAPTPAFSPLYQQIKGLILQSLQQGEWKPGEAIPSEMELAARFRVS
QGTVRKAIDELAAENLVMRRQGKGTFVATHAERHVQYRFLKLQPDVGDPDAEGPAQRRIVECRRTRASADVARALALRGG
DAVVMARRILSFAGVPTILEDIWLPGQTFKGLTAERLADYPGPTYAMFELDFGVRMVRADEKIRAVLPDAAQAGLLGVPA
GTPLLSVERTAYTYNDVPMELRRGLYRTDTHHYHNALQ

Specific function: May regulate the transcription of the frlABCD operon [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082252, Length=227, Percent_Identity=26.8722466960352, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1786950, Length=232, Percent_Identity=25, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1790540, Length=206, Percent_Identity=30.5825242718447, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790118, Length=210, Percent_Identity=27.6190476190476, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 30294; Mature: 30294

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50949 HTH_GNTR ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRTAAHGARAPTNRMSTPPAATPDSPAPTAGGAGAPTPAFSPLYQQIKGLILQSLQQGE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
WKPGEAIPSEMELAARFRVSQGTVRKAIDELAAENLVMRRQGKGTFVATHAERHVQYRFL
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHCEEEEEE
KLQPDVGDPDAEGPAQRRIVECRRTRASADVARALALRGGDAVVMARRILSFAGVPTILE
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHH
DIWLPGQTFKGLTAERLADYPGPTYAMFELDFGVRMVRADEKIRAVLPDAAQAGLLGVPA
HHCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCEEEEECCHHHHHHCCCHHHCCEEECCC
GTPLLSVERTAYTYNDVPMELRRGLYRTDTHHYHNALQ
CCCEEEEEHHEEECCCCCHHHHCCHHHCCCHHHHHCCC
>Mature Secondary Structure
MMRTAAHGARAPTNRMSTPPAATPDSPAPTAGGAGAPTPAFSPLYQQIKGLILQSLQQGE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
WKPGEAIPSEMELAARFRVSQGTVRKAIDELAAENLVMRRQGKGTFVATHAERHVQYRFL
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHCEEEEEE
KLQPDVGDPDAEGPAQRRIVECRRTRASADVARALALRGGDAVVMARRILSFAGVPTILE
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHH
DIWLPGQTFKGLTAERLADYPGPTYAMFELDFGVRMVRADEKIRAVLPDAAQAGLLGVPA
HHCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCEEEEECCHHHHHHCCCHHHCCEEECCC
GTPLLSVERTAYTYNDVPMELRRGLYRTDTHHYHNALQ
CCCEEEEEHHEEECCCCCHHHHCCHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]