Click here to switch to the map view.

The map label for this gene is gacS [H]

Identifier: 120610741

GI number: 120610741

Start: 2259155

End: 2264023

Strand: Direct

Name: gacS [H]

Synonym: Aave_2063

Alternate gene names: 120610741

Gene position: 2259155-2264023 (Clockwise)

Preceding gene: 120610738

Following gene: 120610742

Centisome position: 42.21

GC content: 72.09

Gene sequence:

>4869_bases
ATGAGCCCGCGGCTGGGCAGCCTGTCCGCCCTGTTCGACAAGGTGGCCCAGCGCGACGGCCAGTGGCTGCGGGGCTGGGC
CGTGGTGCTGGCGCTGTCCGCCGTCGGGGCATGGCTGGCCGTGGCCGGCGTGGCCGAGTGGCGGGAGGCCAGCCGCGCGC
AGGAGCGCGAAGGCCTGCTGGGCCATGCCGCCGAGGTGCTGATGAGCCAGACTGCCGGCAGCCCGCTGCTGGGCGCGGTG
GCCTTGCTGGGCCTGAGCGAGCCCACGCTGAAGGCCGTCGCGCTCGGCACGCTGCCGCCCAACGCCCCGGAAGCGCTGGC
CCGCCTGGCCGTGGCGCGCGGCCGCTTCCTGGTCAGCGGGGTGTACGTGCTGGACGCCAGCGGCCGCGTGGTGGCGCACG
AGACGCCGGCCACTCCGGCCCTGGGGCTGGACCTGTCCCACCGACCGTACTTCCTGCAGGCGATGCGCGGCGCGGTGAAC
GTGTATCCCGCGCTCGGCACGAATTCGCAGGACCGCGGGCTGTACTACGCCGCGCCGCTCTACGAGGGCGATACGCCCGC
GAGCGTGATCGTGGGCGTGGTGCTCGTGAAAATGTCCTTCGAGCCCGTGGAGACCCAGTTGCAGCGCTCCGGCTATCCGA
TGGCGCTGATGTCCCCGCAGGGCATCGCCTTCGCCGCCACCCGGCCGGAGTGGCGCTACGCCATCGCGCCGCCGCTGACG
CAGGAGCGCATCGATGCGATCCGGCGGCAGCGCCAGTTCGGCGCGCTGTTCGACAACGGCGTGGCGCAGGCCCTGCCGTT
CCGGCCGGATGCGCGCGAGGCCGTGGTGGGCGGGGTGCGCTATGCGCTGGAGCGCCGCAACCTCGAGTGGCACGATCCGG
ACGGGCCGTGGCAGATCGTGATGCTCGACGACCTGCAGGCGCTGCTGCCGGGGCCGCAGCGCTGGCAGATCGGCGTGGGC
GTCTTCACCCTGCTGGTGGTGCTGGGCGGCATGCTGCTGGACATGATGCGCCACCGGGCCCGCATGGCGCTGGCCATGGA
GCGCTTCCGCGTGCTGGGCGCGGCGCTGCAGTCCAGCCCCGTGGCCGTGGTCATCACCGATGCCGAGGGCCGCATCGACT
GGGTGAACTCGCAGTACGAAGCCAACACCGGCTACAGCCTGGACGAGGTGCGTGGCCGCAGGCCCTCGCTGGTGGCCTCG
GGGCAGACCCCGCCGGAGACCTACCGGCAGATGTGGTCGCGGCTGATCGCGGGCCTGCCCTGGCGCGGCGAGTTCATCAA
CCAGCGCCAGGACGGCACGATCTACCACGACGAGGCCACGCTCTCGCCGGTGTTCGACGACCATGGCCGGCGCATCGCCA
TCGTGGGCCTGCACGAGAACGTGACCGAGCGCATCACGGCCCACCAGGAACTGCAGCGGCGCGAACGTGAACTCAACGAG
GCGCTCGCGCAGCAGACGGCCATCTTCGACAACGCGCCGCCGGTGCTGATCGTGGCCGACGGCCGCCTGCTGCGCTTCAA
CCCCGCCTGCCTGGAACTGCTGGGCGCGCAGCCGGGGCAACTGGAAGGGCGCGGGGTGGAGGTCATCTTCGGCGGCGAGG
AGCTCCACCGGCGCTTCCTCGAGCGCGTCGAGGGCCGGCTGGAGGCCGGCGAATCCGTGCGGGAGGTCGCCCGGCTGGTG
CGCCGGGACGGCACGGTCTTCGAGGCACGCCTCTCGGGCCGCCTGCTGCCGCTGCAGGGCTATGGGCTTGCCTGCATCTG
GGTGGTCGAGGACGTCACCGAGGCGCGGCGCTCCGAGGCGGCCATGCGCGAGATGAACGAGCGCCTGATACTGGCGCAGG
AGGCCGGCCGCGTCGGCGTCTTCGACCTCGACCTCGCGCGCGACCATCTCGTGTTCAGCGAAAAGCTCGCATCCCTCTAC
GGCCTGCCGCACCAGCCGCAGGGACTGCGGCTGATGGACTGGATGGACAGCCTGCACCTGGAGGACAGGCCGCGTGTGCA
GGCCCGCCTCGATGCCGCCCTGGCGGGAGCGGCCACCGGGCTGCAGGATTCCTGGCGCGTGGTGCGTCCCGATGGAAGCG
AGCGCTGGCTGCTGTGCTCGGCACGCATCGAGCGGGATGCCGAGGGGCGGGCGCGGCGGCTCATCGGCGTGCAGGTGGAC
GTGCATGAGCAGAAGCAACTGGAAGCCCGCCTCGCGGACCAGCTCGCGTTCCAGCAGGCGCTCGTGGACGCCATTCCGAT
CCCGCTCTTCCACAAGGACGGGGACGGGCGCTACCGGGGATTCAACCGGGCCTACGAGGAGGCCTTCGGCATCCGCCGGG
AGGACTTCCTGGGCAAGACGGTGCACGAGGCGGACTTTCTCAACCAGGCCGAGCGCGCCGAATTCGAGGCCGACGCCCGC
ACCATCCGCGCCGGCGGGCCGCCGATCCACAAGGAGGTCGATCTCACCTATGCCGACGGGGAGATCCACCACACGCTGTT
CTGGATGCACGGCTTCCAGCGGCCCGACGGCTCGCCCGGCGGCTCCATCGGGACGCTGGTGGACATCACCGACCGCCAGC
GGGCCGAGCGCGAGCTGCGCCGGGCCAAGGAGCTGGCCGAGGAAACCACGGCGCTCAAGTCCAACTTCCTGGCCAACATG
AGCCATGAGATCCGCACGCCGATGAACGCCATCATCGGGATGTCGCACCTCGCGCTCAAGTCGGGACTCACGCCGCGCCA
GGCCGACTACGTCGCCAAGATCCAGCAGGCCGGCCAGCACCTGCTGGGTGTGATCAACGACATCCTGGACTTCTCCCGCA
TCGAGGCCGGCAAGCTGGTCGTGGAAAAGCAGCCCTTCATGCTCGACCGCGTGCTGGAGGGCATGGCCGACGTGGTGGGC
TACAAGGCCGGCGTGAAAGGGCTGGAGCTGGTGCTCGACGTGGCGCCCGACGTGCCGCCCCACCTCGTGGGCGATGCCCT
GCGGCTGGGCCAGATCCTCATCAATTTCGCCAACAACGCGATCAAGTTCACCGAGCGCGGCGAGATCCACGTGCGCGTGC
GGGTGGTGGAGCGCCACGGCCGGCGCGTGCTGCTGCGCTTCGAGGTGCGCGATACCGGCATCGGCGTGGCGCCCGAGCAG
ATGGGCCGGCTCTTCCAGAGCTTCCAGCAGGCCGACGCCTCCACCACGCGGCGCTTCGGGGGCAGCGGCCTGGGGCTGGC
CATCTCCAAGAACCTGGCCGAGCTCATGGGCGGCGAGGTCGGCGCCGAAAGCGTCCTGGGCGAGGGTTCGACCTTCTGGG
TCATGCTGCCGCTCGAATGCGTCGAAGGCGCGCTGGCCGCGCCGCCCCTGCCGCCCGCCCTGCGCAACGGTCGCGTGCTC
ATCGTGGACGACAACCACACGGCCGCCGCCGTGCTCTCGGAAATGCTGCGCAGCATGGGCTTCGAAACCCGCGAATCCCA
TGCCGGCGCGCAGGCGCTGGACATGCTGCGAGATGCCGCGGCGGACGGCGAGCCCTACGGGCTGCTGCTCATCGACTGGC
GCATGCCGGGCATGGATGGCATCGAGCTGGCCCGGCGCATCCACGAGCTGGGCCTGGACCAGGCACCGCAGATGCTCATG
GTCACGGCCTACGGCCGCGACGAGATCATGCCGGCCGCGCGGGAGCAGGGCATCGAGACGGTGCTGGTCAAGCCGGTGAG
CGCCTCGCTCCTCTACGACACGCTGGCGCAGCCCCTGGCCCATGGCTGGCTGCCGGCCCACGCGCACCTGGCGCGGCCCG
ACGACGACCAGCCGCCGCCGCAGCTGCGCGGCGCCTCCGTGCTGCTGGTGGAGGACAACGAACTGAACCAGCTCGTGGCC
GTGGAACTGCTGCGCGGTGCCGGTTTCATCGTGGACGTGGCGGCCCACGGGCAGGCGGCGCTGGACTGCGTGGCCCACAC
CGAATACGACGTGGTGCTCATGGACATGCAGATGCCCGTGATGGACGGCGAGACGGCCACGCGCCGCCTGCGCGCCGATC
CGCGGCACGCGCGCCTGCCCATCATCGCGATGACCGCGAACGCGATGGAGGCCGACCGGCGCCGCTGCTTCGACGCCGGC
ATGAACGACCACGTTCCCAAGCCGATCGAGCCGGGCGTGCTGTGGCGTGCGCTGGCCCGCTGGGTGCGCCCGCGGCCGGG
CATCGGCATCGACGGCGCCCTGGGCGACCCGGCGCCGGCCGGTGCGGGGCAGGGCGGCGCGCAGGAGGCGCTGCCGCATG
GCGTGGACGGCCTGGACATCTCCGCCGGCCTGCAGCGTGCCCTGGGCCGGCCCGCGCTCTACGGCGACCTCCTGCGGCGC
TTCATGGACGGGCAGCGCGACACCGCGGCCGCCCTGCAGGCCGCGCTGCATGGAGGCGACCGCCCCCTGGCGGAGCGGCT
CGCGCACACCCTCAAGTCGGTGGCGGGCAATATCGGCGCCGTTGCGCTGGCGCACGCCGCGCACCAGCTCGAGCAGGCCC
TGCGCGGCGAAGGTGCCGAGGGCGATGTCTCCGCCCAGGCCCTGGTGGTTTGCGACCGGCTCGATACCCTGCTGCTCGGG
CTGGCGCAATGGCGTCTCGCGGGCATGCCGCCGGTCGCGGCCCCGGCTGGCGCCGTGCCGTGGCGCGACGGGGGCGAAGG
CGGTACGGAATCCGCCCAGCAGTCCGCGCTCGCGCAACTGCGCGTCCTGCTGCGTGCCGACGATCCCGGCGCCCTGGATT
TCCTGCAGCAGCAGGCCCTGCTGCTGCGCCGCGCCCTCGGGCCCGGCTTCGCCGCCGTGGAGACGCACGTGCGCGACTTC
GATTTCGAACACGCGCTGGCGATCATCGACGCGCCGCCGGAGCCCTCCACCGTTTCCGGCGCCGCGTGA

Upstream 100 bases:

>100_bases
TTCCTGTAGCCGCCTTGCGGCCGGCCGGGCCGCGGCGCCACGGGCGTCCGCACGGCCCGCCGGGCAGTCCGGGGCCGGCC
TCCGGGGGGTATCCGTGCGC

Downstream 100 bases:

>100_bases
GGCGGCCCGTCCCTCCGCGCCGCAGGCCATCCGAAAGACACAGGCACAGCAACACCATGGACACTTCGCTGCTCTCCGAT
GAACCCATGCTCAAGGACCG

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1622; Mature: 1621

Protein sequence:

>1622_residues
MSPRLGSLSALFDKVAQRDGQWLRGWAVVLALSAVGAWLAVAGVAEWREASRAQEREGLLGHAAEVLMSQTAGSPLLGAV
ALLGLSEPTLKAVALGTLPPNAPEALARLAVARGRFLVSGVYVLDASGRVVAHETPATPALGLDLSHRPYFLQAMRGAVN
VYPALGTNSQDRGLYYAAPLYEGDTPASVIVGVVLVKMSFEPVETQLQRSGYPMALMSPQGIAFAATRPEWRYAIAPPLT
QERIDAIRRQRQFGALFDNGVAQALPFRPDAREAVVGGVRYALERRNLEWHDPDGPWQIVMLDDLQALLPGPQRWQIGVG
VFTLLVVLGGMLLDMMRHRARMALAMERFRVLGAALQSSPVAVVITDAEGRIDWVNSQYEANTGYSLDEVRGRRPSLVAS
GQTPPETYRQMWSRLIAGLPWRGEFINQRQDGTIYHDEATLSPVFDDHGRRIAIVGLHENVTERITAHQELQRRERELNE
ALAQQTAIFDNAPPVLIVADGRLLRFNPACLELLGAQPGQLEGRGVEVIFGGEELHRRFLERVEGRLEAGESVREVARLV
RRDGTVFEARLSGRLLPLQGYGLACIWVVEDVTEARRSEAAMREMNERLILAQEAGRVGVFDLDLARDHLVFSEKLASLY
GLPHQPQGLRLMDWMDSLHLEDRPRVQARLDAALAGAATGLQDSWRVVRPDGSERWLLCSARIERDAEGRARRLIGVQVD
VHEQKQLEARLADQLAFQQALVDAIPIPLFHKDGDGRYRGFNRAYEEAFGIRREDFLGKTVHEADFLNQAERAEFEADAR
TIRAGGPPIHKEVDLTYADGEIHHTLFWMHGFQRPDGSPGGSIGTLVDITDRQRAERELRRAKELAEETTALKSNFLANM
SHEIRTPMNAIIGMSHLALKSGLTPRQADYVAKIQQAGQHLLGVINDILDFSRIEAGKLVVEKQPFMLDRVLEGMADVVG
YKAGVKGLELVLDVAPDVPPHLVGDALRLGQILINFANNAIKFTERGEIHVRVRVVERHGRRVLLRFEVRDTGIGVAPEQ
MGRLFQSFQQADASTTRRFGGSGLGLAISKNLAELMGGEVGAESVLGEGSTFWVMLPLECVEGALAAPPLPPALRNGRVL
IVDDNHTAAAVLSEMLRSMGFETRESHAGAQALDMLRDAAADGEPYGLLLIDWRMPGMDGIELARRIHELGLDQAPQMLM
VTAYGRDEIMPAAREQGIETVLVKPVSASLLYDTLAQPLAHGWLPAHAHLARPDDDQPPPQLRGASVLLVEDNELNQLVA
VELLRGAGFIVDVAAHGQAALDCVAHTEYDVVLMDMQMPVMDGETATRRLRADPRHARLPIIAMTANAMEADRRRCFDAG
MNDHVPKPIEPGVLWRALARWVRPRPGIGIDGALGDPAPAGAGQGGAQEALPHGVDGLDISAGLQRALGRPALYGDLLRR
FMDGQRDTAAALQAALHGGDRPLAERLAHTLKSVAGNIGAVALAHAAHQLEQALRGEGAEGDVSAQALVVCDRLDTLLLG
LAQWRLAGMPPVAAPAGAVPWRDGGEGGTESAQQSALAQLRVLLRADDPGALDFLQQQALLLRRALGPGFAAVETHVRDF
DFEHALAIIDAPPEPSTVSGAA

Sequences:

>Translated_1622_residues
MSPRLGSLSALFDKVAQRDGQWLRGWAVVLALSAVGAWLAVAGVAEWREASRAQEREGLLGHAAEVLMSQTAGSPLLGAV
ALLGLSEPTLKAVALGTLPPNAPEALARLAVARGRFLVSGVYVLDASGRVVAHETPATPALGLDLSHRPYFLQAMRGAVN
VYPALGTNSQDRGLYYAAPLYEGDTPASVIVGVVLVKMSFEPVETQLQRSGYPMALMSPQGIAFAATRPEWRYAIAPPLT
QERIDAIRRQRQFGALFDNGVAQALPFRPDAREAVVGGVRYALERRNLEWHDPDGPWQIVMLDDLQALLPGPQRWQIGVG
VFTLLVVLGGMLLDMMRHRARMALAMERFRVLGAALQSSPVAVVITDAEGRIDWVNSQYEANTGYSLDEVRGRRPSLVAS
GQTPPETYRQMWSRLIAGLPWRGEFINQRQDGTIYHDEATLSPVFDDHGRRIAIVGLHENVTERITAHQELQRRERELNE
ALAQQTAIFDNAPPVLIVADGRLLRFNPACLELLGAQPGQLEGRGVEVIFGGEELHRRFLERVEGRLEAGESVREVARLV
RRDGTVFEARLSGRLLPLQGYGLACIWVVEDVTEARRSEAAMREMNERLILAQEAGRVGVFDLDLARDHLVFSEKLASLY
GLPHQPQGLRLMDWMDSLHLEDRPRVQARLDAALAGAATGLQDSWRVVRPDGSERWLLCSARIERDAEGRARRLIGVQVD
VHEQKQLEARLADQLAFQQALVDAIPIPLFHKDGDGRYRGFNRAYEEAFGIRREDFLGKTVHEADFLNQAERAEFEADAR
TIRAGGPPIHKEVDLTYADGEIHHTLFWMHGFQRPDGSPGGSIGTLVDITDRQRAERELRRAKELAEETTALKSNFLANM
SHEIRTPMNAIIGMSHLALKSGLTPRQADYVAKIQQAGQHLLGVINDILDFSRIEAGKLVVEKQPFMLDRVLEGMADVVG
YKAGVKGLELVLDVAPDVPPHLVGDALRLGQILINFANNAIKFTERGEIHVRVRVVERHGRRVLLRFEVRDTGIGVAPEQ
MGRLFQSFQQADASTTRRFGGSGLGLAISKNLAELMGGEVGAESVLGEGSTFWVMLPLECVEGALAAPPLPPALRNGRVL
IVDDNHTAAAVLSEMLRSMGFETRESHAGAQALDMLRDAAADGEPYGLLLIDWRMPGMDGIELARRIHELGLDQAPQMLM
VTAYGRDEIMPAAREQGIETVLVKPVSASLLYDTLAQPLAHGWLPAHAHLARPDDDQPPPQLRGASVLLVEDNELNQLVA
VELLRGAGFIVDVAAHGQAALDCVAHTEYDVVLMDMQMPVMDGETATRRLRADPRHARLPIIAMTANAMEADRRRCFDAG
MNDHVPKPIEPGVLWRALARWVRPRPGIGIDGALGDPAPAGAGQGGAQEALPHGVDGLDISAGLQRALGRPALYGDLLRR
FMDGQRDTAAALQAALHGGDRPLAERLAHTLKSVAGNIGAVALAHAAHQLEQALRGEGAEGDVSAQALVVCDRLDTLLLG
LAQWRLAGMPPVAAPAGAVPWRDGGEGGTESAQQSALAQLRVLLRADDPGALDFLQQQALLLRRALGPGFAAVETHVRDF
DFEHALAIIDAPPEPSTVSGAA
>Mature_1621_residues
SPRLGSLSALFDKVAQRDGQWLRGWAVVLALSAVGAWLAVAGVAEWREASRAQEREGLLGHAAEVLMSQTAGSPLLGAVA
LLGLSEPTLKAVALGTLPPNAPEALARLAVARGRFLVSGVYVLDASGRVVAHETPATPALGLDLSHRPYFLQAMRGAVNV
YPALGTNSQDRGLYYAAPLYEGDTPASVIVGVVLVKMSFEPVETQLQRSGYPMALMSPQGIAFAATRPEWRYAIAPPLTQ
ERIDAIRRQRQFGALFDNGVAQALPFRPDAREAVVGGVRYALERRNLEWHDPDGPWQIVMLDDLQALLPGPQRWQIGVGV
FTLLVVLGGMLLDMMRHRARMALAMERFRVLGAALQSSPVAVVITDAEGRIDWVNSQYEANTGYSLDEVRGRRPSLVASG
QTPPETYRQMWSRLIAGLPWRGEFINQRQDGTIYHDEATLSPVFDDHGRRIAIVGLHENVTERITAHQELQRRERELNEA
LAQQTAIFDNAPPVLIVADGRLLRFNPACLELLGAQPGQLEGRGVEVIFGGEELHRRFLERVEGRLEAGESVREVARLVR
RDGTVFEARLSGRLLPLQGYGLACIWVVEDVTEARRSEAAMREMNERLILAQEAGRVGVFDLDLARDHLVFSEKLASLYG
LPHQPQGLRLMDWMDSLHLEDRPRVQARLDAALAGAATGLQDSWRVVRPDGSERWLLCSARIERDAEGRARRLIGVQVDV
HEQKQLEARLADQLAFQQALVDAIPIPLFHKDGDGRYRGFNRAYEEAFGIRREDFLGKTVHEADFLNQAERAEFEADART
IRAGGPPIHKEVDLTYADGEIHHTLFWMHGFQRPDGSPGGSIGTLVDITDRQRAERELRRAKELAEETTALKSNFLANMS
HEIRTPMNAIIGMSHLALKSGLTPRQADYVAKIQQAGQHLLGVINDILDFSRIEAGKLVVEKQPFMLDRVLEGMADVVGY
KAGVKGLELVLDVAPDVPPHLVGDALRLGQILINFANNAIKFTERGEIHVRVRVVERHGRRVLLRFEVRDTGIGVAPEQM
GRLFQSFQQADASTTRRFGGSGLGLAISKNLAELMGGEVGAESVLGEGSTFWVMLPLECVEGALAAPPLPPALRNGRVLI
VDDNHTAAAVLSEMLRSMGFETRESHAGAQALDMLRDAAADGEPYGLLLIDWRMPGMDGIELARRIHELGLDQAPQMLMV
TAYGRDEIMPAAREQGIETVLVKPVSASLLYDTLAQPLAHGWLPAHAHLARPDDDQPPPQLRGASVLLVEDNELNQLVAV
ELLRGAGFIVDVAAHGQAALDCVAHTEYDVVLMDMQMPVMDGETATRRLRADPRHARLPIIAMTANAMEADRRRCFDAGM
NDHVPKPIEPGVLWRALARWVRPRPGIGIDGALGDPAPAGAGQGGAQEALPHGVDGLDISAGLQRALGRPALYGDLLRRF
MDGQRDTAAALQAALHGGDRPLAERLAHTLKSVAGNIGAVALAHAAHQLEQALRGEGAEGDVSAQALVVCDRLDTLLLGL
AQWRLAGMPPVAAPAGAVPWRDGGEGGTESAQQSALAQLRVLLRADDPGALDFLQQQALLLRRALGPGFAAVETHVRDFD
FEHALAIIDAPPEPSTVSGAA

Specific function: Forms part of a two-component regulatory system gacA/gacS(lemA). May be involved in lesion formation, swarming and in the production of extracellular protease, syringomycin and N- acyl-L-homoserine lactone (acyl-HSL). Required for pathogenicity on bean [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=641, Percent_Identity=33.0733229329173, Blast_Score=310, Evalue=4e-85,
Organism=Escherichia coli, GI48994928, Length=545, Percent_Identity=29.9082568807339, Blast_Score=213, Evalue=8e-56,
Organism=Escherichia coli, GI145693157, Length=553, Percent_Identity=30.379746835443, Blast_Score=205, Evalue=2e-53,
Organism=Escherichia coli, GI87081816, Length=394, Percent_Identity=34.010152284264, Blast_Score=194, Evalue=3e-50,
Organism=Escherichia coli, GI1788713, Length=574, Percent_Identity=28.5714285714286, Blast_Score=183, Evalue=9e-47,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=28.755364806867, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=31.6017316017316, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1788381, Length=371, Percent_Identity=25.3369272237197, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1786783, Length=238, Percent_Identity=30.2521008403361, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=27.9661016949153, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=26.0504201680672, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1788549, Length=379, Percent_Identity=22.6912928759894, Blast_Score=77, Evalue=8e-15,
Organism=Escherichia coli, GI87082128, Length=265, Percent_Identity=26.0377358490566, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=35.2941176470588, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI1788279, Length=228, Percent_Identity=25.8771929824561, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1790300, Length=269, Percent_Identity=27.1375464684015, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1790437, Length=126, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=123, Percent_Identity=38.2113821138211, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322044, Length=135, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 176783; Mature: 176652

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRLGSLSALFDKVAQRDGQWLRGWAVVLALSAVGAWLAVAGVAEWREASRAQEREGLL
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
GHAAEVLMSQTAGSPLLGAVALLGLSEPTLKAVALGTLPPNAPEALARLAVARGRFLVSG
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEE
VYVLDASGRVVAHETPATPALGLDLSHRPYFLQAMRGAVNVYPALGTNSQDRGLYYAAPL
EEEEECCCCEEEECCCCCCEECCCCCCCCHHHHHHHCHHEEEECCCCCCCCCCEEEEECC
YEGDTPASVIVGVVLVKMSFEPVETQLQRSGYPMALMSPQGIAFAATRPEWRYAIAPPLT
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCCEEEEECCCCCEEEECCCCC
QERIDAIRRQRQFGALFDNGVAQALPFRPDAREAVVGGVRYALERRNLEWHDPDGPWQIV
HHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
MLDDLQALLPGPQRWQIGVGVFTLLVVLGGMLLDMMRHRARMALAMERFRVLGAALQSSP
EECCHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VAVVITDAEGRIDWVNSQYEANTGYSLDEVRGRRPSLVASGQTPPETYRQMWSRLIAGLP
EEEEEECCCCCEEECCCCCCCCCCCCHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCC
WRGEFINQRQDGTIYHDEATLSPVFDDHGRRIAIVGLHENVTERITAHQELQRRERELNE
CCCHHHCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
ALAQQTAIFDNAPPVLIVADGRLLRFNPACLELLGAQPGQLEGRGVEVIFGGEELHRRFL
HHHHHHHHCCCCCCEEEEECCEEEEECHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHH
ERVEGRLEAGESVREVARLVRRDGTVFEARLSGRLLPLQGYGLACIWVVEDVTEARRSEA
HHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCEEEEEEHHHHHHHHHHHH
AMREMNERLILAQEAGRVGVFDLDLARDHLVFSEKLASLYGLPHQPQGLRLMDWMDSLHL
HHHHHHHHEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
EDRPRVQARLDAALAGAATGLQDSWRVVRPDGSERWLLCSARIERDAEGRARRLIGVQVD
CCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEECHHCCCCCCCCEEEEEEEEC
VHEQKQLEARLADQLAFQQALVDAIPIPLFHKDGDGRYRGFNRAYEEAFGIRREDFLGKT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHHCCH
VHEADFLNQAERAEFEADARTIRAGGPPIHKEVDLTYADGEIHHTLFWMHGFQRPDGSPG
HHHHHHHHHHHHHHHHHCHHEEECCCCCCCCEEEEEEECCCHHHHEEEECCCCCCCCCCC
GSIGTLVDITDRQRAERELRRAKELAEETTALKSNFLANMSHEIRTPMNAIIGMSHLALK
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
SGLTPRQADYVAKIQQAGQHLLGVINDILDFSRIEAGKLVVEKQPFMLDRVLEGMADVVG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHH
YKAGVKGLELVLDVAPDVPPHLVGDALRLGQILINFANNAIKFTERGEIHVRVRVVERHG
HHCCCCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEEEECCC
RRVLLRFEVRDTGIGVAPEQMGRLFQSFQQADASTTRRFGGSGLGLAISKNLAELMGGEV
CEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCCHHHHHHHHHHHCCCC
GAESVLGEGSTFWVMLPLECVEGALAAPPLPPALRNGRVLIVDDNHTAAAVLSEMLRSMG
CHHHHHCCCCEEEEEEEHHHHCCCCCCCCCCHHHCCCEEEEEECCCHHHHHHHHHHHHCC
FETRESHAGAQALDMLRDAAADGEPYGLLLIDWRMPGMDGIELARRIHELGLDQAPQMLM
CCCHHHCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEE
VTAYGRDEIMPAAREQGIETVLVKPVSASLLYDTLAQPLAHGWLPAHAHLARPDDDQPPP
EEECCCCCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QLRGASVLLVEDNELNQLVAVELLRGAGFIVDVAAHGQAALDCVAHTEYDVVLMDMQMPV
CCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCEEEEEECCCC
MDGETATRRLRADPRHARLPIIAMTANAMEADRRRCFDAGMNDHVPKPIEPGVLWRALAR
CCCCHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
WVRPRPGIGIDGALGDPAPAGAGQGGAQEALPHGVDGLDISAGLQRALGRPALYGDLLRR
HCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHH
FMDGQRDTAAALQAALHGGDRPLAERLAHTLKSVAGNIGAVALAHAAHQLEQALRGEGAE
HHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
GDVSAQALVVCDRLDTLLLGLAQWRLAGMPPVAAPAGAVPWRDGGEGGTESAQQSALAQL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
RVLLRADDPGALDFLQQQALLLRRALGPGFAAVETHVRDFDFEHALAIIDAPPEPSTVSG
HHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCC
AA
CC
>Mature Secondary Structure 
SPRLGSLSALFDKVAQRDGQWLRGWAVVLALSAVGAWLAVAGVAEWREASRAQEREGLL
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
GHAAEVLMSQTAGSPLLGAVALLGLSEPTLKAVALGTLPPNAPEALARLAVARGRFLVSG
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEE
VYVLDASGRVVAHETPATPALGLDLSHRPYFLQAMRGAVNVYPALGTNSQDRGLYYAAPL
EEEEECCCCEEEECCCCCCEECCCCCCCCHHHHHHHCHHEEEECCCCCCCCCCEEEEECC
YEGDTPASVIVGVVLVKMSFEPVETQLQRSGYPMALMSPQGIAFAATRPEWRYAIAPPLT
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCCEEEEECCCCCEEEECCCCC
QERIDAIRRQRQFGALFDNGVAQALPFRPDAREAVVGGVRYALERRNLEWHDPDGPWQIV
HHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
MLDDLQALLPGPQRWQIGVGVFTLLVVLGGMLLDMMRHRARMALAMERFRVLGAALQSSP
EECCHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VAVVITDAEGRIDWVNSQYEANTGYSLDEVRGRRPSLVASGQTPPETYRQMWSRLIAGLP
EEEEEECCCCCEEECCCCCCCCCCCCHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCC
WRGEFINQRQDGTIYHDEATLSPVFDDHGRRIAIVGLHENVTERITAHQELQRRERELNE
CCCHHHCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
ALAQQTAIFDNAPPVLIVADGRLLRFNPACLELLGAQPGQLEGRGVEVIFGGEELHRRFL
HHHHHHHHCCCCCCEEEEECCEEEEECHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHH
ERVEGRLEAGESVREVARLVRRDGTVFEARLSGRLLPLQGYGLACIWVVEDVTEARRSEA
HHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCEEEEEEHHHHHHHHHHHH
AMREMNERLILAQEAGRVGVFDLDLARDHLVFSEKLASLYGLPHQPQGLRLMDWMDSLHL
HHHHHHHHEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
EDRPRVQARLDAALAGAATGLQDSWRVVRPDGSERWLLCSARIERDAEGRARRLIGVQVD
CCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEECHHCCCCCCCCEEEEEEEEC
VHEQKQLEARLADQLAFQQALVDAIPIPLFHKDGDGRYRGFNRAYEEAFGIRREDFLGKT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHHCCH
VHEADFLNQAERAEFEADARTIRAGGPPIHKEVDLTYADGEIHHTLFWMHGFQRPDGSPG
HHHHHHHHHHHHHHHHHCHHEEECCCCCCCCEEEEEEECCCHHHHEEEECCCCCCCCCCC
GSIGTLVDITDRQRAERELRRAKELAEETTALKSNFLANMSHEIRTPMNAIIGMSHLALK
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
SGLTPRQADYVAKIQQAGQHLLGVINDILDFSRIEAGKLVVEKQPFMLDRVLEGMADVVG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHH
YKAGVKGLELVLDVAPDVPPHLVGDALRLGQILINFANNAIKFTERGEIHVRVRVVERHG
HHCCCCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEEEECCC
RRVLLRFEVRDTGIGVAPEQMGRLFQSFQQADASTTRRFGGSGLGLAISKNLAELMGGEV
CEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCCHHHHHHHHHHHCCCC
GAESVLGEGSTFWVMLPLECVEGALAAPPLPPALRNGRVLIVDDNHTAAAVLSEMLRSMG
CHHHHHCCCCEEEEEEEHHHHCCCCCCCCCCHHHCCCEEEEEECCCHHHHHHHHHHHHCC
FETRESHAGAQALDMLRDAAADGEPYGLLLIDWRMPGMDGIELARRIHELGLDQAPQMLM
CCCHHHCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEE
VTAYGRDEIMPAAREQGIETVLVKPVSASLLYDTLAQPLAHGWLPAHAHLARPDDDQPPP
EEECCCCCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QLRGASVLLVEDNELNQLVAVELLRGAGFIVDVAAHGQAALDCVAHTEYDVVLMDMQMPV
CCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCEEEEEECCCC
MDGETATRRLRADPRHARLPIIAMTANAMEADRRRCFDAGMNDHVPKPIEPGVLWRALAR
CCCCHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
WVRPRPGIGIDGALGDPAPAGAGQGGAQEALPHGVDGLDISAGLQRALGRPALYGDLLRR
HCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHH
FMDGQRDTAAALQAALHGGDRPLAERLAHTLKSVAGNIGAVALAHAAHQLEQALRGEGAE
HHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
GDVSAQALVVCDRLDTLLLGLAQWRLAGMPPVAAPAGAVPWRDGGEGGTESAQQSALAQL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
RVLLRADDPGALDFLQQQALLLRRALGPGFAAVETHVRDFDFEHALAIIDAPPEPSTVSG
HHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCC
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1314807 [H]