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The map label for this gene is yciR [C]

Identifier: 120610176

GI number: 120610176

Start: 1651238

End: 1653412

Strand: Reverse

Name: yciR [C]

Synonym: Aave_1490

Alternate gene names: 120610176

Gene position: 1653412-1651238 (Counterclockwise)

Preceding gene: 120610178

Following gene: 120610175

Centisome position: 30.89

GC content: 69.01

Gene sequence:

>2175_bases
ATGCCGTCGCACTACGATCCGATGGTGGTGGCGGCGTCGTTCGCCATCGCGGTGCTGGCCAGCTACGTCACGCTGGATCT
GGCGCGCCGCGTGCATGTGTCGCAGCGGCACATCGGCCTGGTCTGGTGGGCCGCAGGCTCGGTGGTGATGGGCACGGGCA
TCTGGGCCATGCACTTTTTGGGCATGCAGGCATTCCAGCTGCCCATCGCGCTGGGATTTTCCGGCGGCCTCACCCTGCTG
TCCTGGCTGGCGGCGGTGCTGGCTTCGGCACTGGCGCTGGGGATGGCCAGCCTGCCGCGGTTCGGCCGGTGGCAGATCCT
CTTCGGCGCCGTATGCATGGGCAGCGGTATCAGCGGCATGCACTACATCGGCATGAAAGCCATGAAGATGTCCATCGACA
TCGTGTGGGATCCCGTGCTGGTGGCGCTGTCGGTCGCAGTGGCGTTTTTCGCCTCGGCCACGGCGCTGCGCATCTTCCAG
TGGCTGATCCACGTACGGCAGGACCGGCGCAGGGCGTGGTACCAGGCGGCTGCGGCGCTGATCATGGGCATCGCGATCTG
CGGCATGCACTACACGGGCATGGCTGCGGCGTCGTTCCCCGAAGGCTCGATCTGCCTGAGCGCCGACGGCCTCGGCGGAC
CGGGCCTGACGGCCATGGTATTGCTGTCGTCCGGCATGCTGCTGCTGAGCACGCTGTTCACCGCCGTGCTGGACGCGCGC
CTGCAGAGCACGGCCCGGCAACTCAACGCCTCCCTGCAGGAGAGCAATGCGCGCCTCACCGAAGCCAATGCCCAGCTGCA
GAAGCAGGCCTTCGCGGACCCCCTGACCCTGCTGCCCAACCGGCTACTGTTCGAGGACCGCCTGTCCCACGCCCTGCTGC
GCCTGGACCGCATGCGGCGCCGCGATGCCGGCCAGCGTCTGGGCGTGATGTTCGTGGACCTGGACGGCTTCAAGCCCATC
AACGACTCCTTCGGCCATGCGGCGGGGGACGCCATCCTGCGCAGCGCCGCGGAGCGCCTGCGGCTGCAGGCCCGCGAGAG
CGACACGGTGGCCCGCGTGGGCGGCGACGAATTCCTGCTCCTGCTGGAAAACGTGAACGACCCGGCCGACTGCCTCGCGG
TGGCGAACCGGCTGCTCAATTCCCTGGGCCAGCCGTTCGAGGTGGCGGGCAAGACCGTGCAGATCGCCTGCTCCGTCGGC
ATCGTGGTGTATCCGGACCACGGCGAGCGCGACAAGCTCGTCGCGAACGCCGACGCCGCCATGTATGCCGCCAAGCGGGC
CGGCGGCAACGGCTATGCGATGTTCGAGTCGCACATGGACTCCGACGCCACGGCCCAGCTGTCGCTTCAGCACGACCTGC
GGCAGGCGATAGCCCGCGGAGAACTGTCGCTGCACTACCAGCCCAAGATCGACGCCCGGCGCGGCCGCATCAACGGCGTG
GAGGCCCTGCTGCGCTGGCGGCATCCCCTGCGGGGCAACGTCAGTCCGGCCGAGTTCATTCCCGTGGCCGAGCGCTTCGG
GCTCATCGCGCAGCTCGGCAACTGGGTGATCGAGGAGGCCTGCAGGCAGATGGCCGCGTGGAGCTGGGACGGGCTGCGCA
TGCGCGTGGCCATCAACCTCTCGGCCTACCAACTGCGCGAAAGCGGTCTTGCCGACCGCATCCGCGACGCCCTGCAGCGG
CACGGCGTGCCGGCCTCGCACCTGCTGTGCGAGATCACCGAATCGGTGGCGATGGAAGACACGCGTGCCACCCAGCGGGC
TATCGAGGAACTGGGCCGCATCGGCGTGTACCTGTCCATCGACGACTTCGGCACGGGCTATTCCAGCCTGCACTACCTGC
GCAGCCTGCCGGCGCGCCAGCTCAAGATCGACCGCAGCTTCGTGCGCGACCTGGAGGAGCAGGAAGACGCACGCGCCGTG
GTGGACGCCGTGGTGCGGCTGGCGCACGCCCTGGGCCTGCGCGTCGTGGCCGAAGGCGTGGAAACGGAAGGCCAGCGCGA
CATCCTGGCGGCCATGCACTGCGACGAACTGCAGGGCTTCTACTTCGCCCGGCCCATGCCGGCCGACACCCTGCTCGCCT
GGGCCGTGGGCGACAAGCCCGAGGGCGCGGCGGATTTCAGCCCGTCCATCATCGACCTGCAGGCGCTCGACCCCTCAGTG
GACGCACCGGCCTGA

Upstream 100 bases:

>100_bases
CGGCAAGGCCTGTAACCAATAGATACACTACGGCGCTGCGCCGCGATGGGCGGTCGCCTCCACCATGTCCGCTACTTCCA
ATTTCGCCCTGACCGCCTTC

Downstream 100 bases:

>100_bases
TGTTCCACGGTCGGCAAGCACCTCGCCGGGGCGCGGCGCGATAATCATGGCCGTCAGTCCTACCTACAACGCATCCCCAC
CATGAGCACCACCATCCGGT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 723

Protein sequence:

>724_residues
MPSHYDPMVVAASFAIAVLASYVTLDLARRVHVSQRHIGLVWWAAGSVVMGTGIWAMHFLGMQAFQLPIALGFSGGLTLL
SWLAAVLASALALGMASLPRFGRWQILFGAVCMGSGISGMHYIGMKAMKMSIDIVWDPVLVALSVAVAFFASATALRIFQ
WLIHVRQDRRRAWYQAAAALIMGIAICGMHYTGMAAASFPEGSICLSADGLGGPGLTAMVLLSSGMLLLSTLFTAVLDAR
LQSTARQLNASLQESNARLTEANAQLQKQAFADPLTLLPNRLLFEDRLSHALLRLDRMRRRDAGQRLGVMFVDLDGFKPI
NDSFGHAAGDAILRSAAERLRLQARESDTVARVGGDEFLLLLENVNDPADCLAVANRLLNSLGQPFEVAGKTVQIACSVG
IVVYPDHGERDKLVANADAAMYAAKRAGGNGYAMFESHMDSDATAQLSLQHDLRQAIARGELSLHYQPKIDARRGRINGV
EALLRWRHPLRGNVSPAEFIPVAERFGLIAQLGNWVIEEACRQMAAWSWDGLRMRVAINLSAYQLRESGLADRIRDALQR
HGVPASHLLCEITESVAMEDTRATQRAIEELGRIGVYLSIDDFGTGYSSLHYLRSLPARQLKIDRSFVRDLEEQEDARAV
VDAVVRLAHALGLRVVAEGVETEGQRDILAAMHCDELQGFYFARPMPADTLLAWAVGDKPEGAADFSPSIIDLQALDPSV
DAPA

Sequences:

>Translated_724_residues
MPSHYDPMVVAASFAIAVLASYVTLDLARRVHVSQRHIGLVWWAAGSVVMGTGIWAMHFLGMQAFQLPIALGFSGGLTLL
SWLAAVLASALALGMASLPRFGRWQILFGAVCMGSGISGMHYIGMKAMKMSIDIVWDPVLVALSVAVAFFASATALRIFQ
WLIHVRQDRRRAWYQAAAALIMGIAICGMHYTGMAAASFPEGSICLSADGLGGPGLTAMVLLSSGMLLLSTLFTAVLDAR
LQSTARQLNASLQESNARLTEANAQLQKQAFADPLTLLPNRLLFEDRLSHALLRLDRMRRRDAGQRLGVMFVDLDGFKPI
NDSFGHAAGDAILRSAAERLRLQARESDTVARVGGDEFLLLLENVNDPADCLAVANRLLNSLGQPFEVAGKTVQIACSVG
IVVYPDHGERDKLVANADAAMYAAKRAGGNGYAMFESHMDSDATAQLSLQHDLRQAIARGELSLHYQPKIDARRGRINGV
EALLRWRHPLRGNVSPAEFIPVAERFGLIAQLGNWVIEEACRQMAAWSWDGLRMRVAINLSAYQLRESGLADRIRDALQR
HGVPASHLLCEITESVAMEDTRATQRAIEELGRIGVYLSIDDFGTGYSSLHYLRSLPARQLKIDRSFVRDLEEQEDARAV
VDAVVRLAHALGLRVVAEGVETEGQRDILAAMHCDELQGFYFARPMPADTLLAWAVGDKPEGAADFSPSIIDLQALDPSV
DAPA
>Mature_723_residues
PSHYDPMVVAASFAIAVLASYVTLDLARRVHVSQRHIGLVWWAAGSVVMGTGIWAMHFLGMQAFQLPIALGFSGGLTLLS
WLAAVLASALALGMASLPRFGRWQILFGAVCMGSGISGMHYIGMKAMKMSIDIVWDPVLVALSVAVAFFASATALRIFQW
LIHVRQDRRRAWYQAAAALIMGIAICGMHYTGMAAASFPEGSICLSADGLGGPGLTAMVLLSSGMLLLSTLFTAVLDARL
QSTARQLNASLQESNARLTEANAQLQKQAFADPLTLLPNRLLFEDRLSHALLRLDRMRRRDAGQRLGVMFVDLDGFKPIN
DSFGHAAGDAILRSAAERLRLQARESDTVARVGGDEFLLLLENVNDPADCLAVANRLLNSLGQPFEVAGKTVQIACSVGI
VVYPDHGERDKLVANADAAMYAAKRAGGNGYAMFESHMDSDATAQLSLQHDLRQAIARGELSLHYQPKIDARRGRINGVE
ALLRWRHPLRGNVSPAEFIPVAERFGLIAQLGNWVIEEACRQMAAWSWDGLRMRVAINLSAYQLRESGLADRIRDALQRH
GVPASHLLCEITESVAMEDTRATQRAIEELGRIGVYLSIDDFGTGYSSLHYLRSLPARQLKIDRSFVRDLEEQEDARAVV
DAVVRLAHALGLRVVAEGVETEGQRDILAAMHCDELQGFYFARPMPADTLLAWAVGDKPEGAADFSPSIIDLQALDPSVD
APA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=435, Percent_Identity=39.0804597701149, Blast_Score=299, Evalue=3e-82,
Organism=Escherichia coli, GI87081921, Length=424, Percent_Identity=36.5566037735849, Blast_Score=275, Evalue=7e-75,
Organism=Escherichia coli, GI226510982, Length=438, Percent_Identity=27.6255707762557, Blast_Score=192, Evalue=9e-50,
Organism=Escherichia coli, GI1790496, Length=248, Percent_Identity=37.0967741935484, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI87081845, Length=257, Percent_Identity=34.6303501945525, Blast_Score=152, Evalue=8e-38,
Organism=Escherichia coli, GI87081980, Length=264, Percent_Identity=36.7424242424242, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1787055, Length=394, Percent_Identity=28.9340101522843, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1788502, Length=246, Percent_Identity=34.9593495934959, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87082096, Length=429, Percent_Identity=26.5734265734266, Blast_Score=139, Evalue=8e-34,
Organism=Escherichia coli, GI87081743, Length=248, Percent_Identity=33.0645161290323, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786507, Length=247, Percent_Identity=31.1740890688259, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1788849, Length=255, Percent_Identity=32.156862745098, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1788381, Length=174, Percent_Identity=36.7816091954023, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788956, Length=175, Percent_Identity=33.7142857142857, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87081977, Length=171, Percent_Identity=35.672514619883, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=33.5365853658537, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789650, Length=460, Percent_Identity=21.304347826087, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1786584, Length=246, Percent_Identity=28.4552845528455, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082007, Length=172, Percent_Identity=36.6279069767442, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787802, Length=134, Percent_Identity=34.3283582089552, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=30.8176100628931, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI87081881, Length=167, Percent_Identity=32.3353293413174, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=30.9090909090909, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 78814; Mature: 78683

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50924 MHYT ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSHYDPMVVAASFAIAVLASYVTLDLARRVHVSQRHIGLVWWAAGSVVMGTGIWAMHFL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEHHHHHHHHHH
GMQAFQLPIALGFSGGLTLLSWLAAVLASALALGMASLPRFGRWQILFGAVCMGSGISGM
HHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCH
HYIGMKAMKMSIDIVWDPVLVALSVAVAFFASATALRIFQWLIHVRQDRRRAWYQAAAAL
HHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMGIAICGMHYTGMAAASFPEGSICLSADGLGGPGLTAMVLLSSGMLLLSTLFTAVLDAR
HHHHHHHHCHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
LQSTARQLNASLQESNARLTEANAQLQKQAFADPLTLLPNRLLFEDRLSHALLRLDRMRR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
RDAGQRLGVMFVDLDGFKPINDSFGHAAGDAILRSAAERLRLQARESDTVARVGGDEFLL
HCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEE
LLENVNDPADCLAVANRLLNSLGQPFEVAGKTVQIACSVGIVVYPDHGERDKLVANADAA
EEECCCCHHHHHHHHHHHHHHCCCCHHHCCCEEEEEEEEEEEEECCCCCCCCEEECCHHH
MYAAKRAGGNGYAMFESHMDSDATAQLSLQHDLRQAIARGELSLHYQPKIDARRGRINGV
HHHHHHCCCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHH
EALLRWRHPLRGNVSPAEFIPVAERFGLIAQLGNWVIEEACRQMAAWSWDGLRMRVAINL
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
SAYQLRESGLADRIRDALQRHGVPASHLLCEITESVAMEDTRATQRAIEELGRIGVYLSI
HHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEE
DDFGTGYSSLHYLRSLPARQLKIDRSFVRDLEEQEDARAVVDAVVRLAHALGLRVVAEGV
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ETEGQRDILAAMHCDELQGFYFARPMPADTLLAWAVGDKPEGAADFSPSIIDLQALDPSV
CCCCCHHHHHHHHHHHHCCEEEECCCCHHHEEEEECCCCCCCCCCCCCCEEEEEECCCCC
DAPA
CCCC
>Mature Secondary Structure 
PSHYDPMVVAASFAIAVLASYVTLDLARRVHVSQRHIGLVWWAAGSVVMGTGIWAMHFL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEHHHHHHHHHH
GMQAFQLPIALGFSGGLTLLSWLAAVLASALALGMASLPRFGRWQILFGAVCMGSGISGM
HHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCH
HYIGMKAMKMSIDIVWDPVLVALSVAVAFFASATALRIFQWLIHVRQDRRRAWYQAAAAL
HHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMGIAICGMHYTGMAAASFPEGSICLSADGLGGPGLTAMVLLSSGMLLLSTLFTAVLDAR
HHHHHHHHCHHCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
LQSTARQLNASLQESNARLTEANAQLQKQAFADPLTLLPNRLLFEDRLSHALLRLDRMRR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
RDAGQRLGVMFVDLDGFKPINDSFGHAAGDAILRSAAERLRLQARESDTVARVGGDEFLL
HCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEE
LLENVNDPADCLAVANRLLNSLGQPFEVAGKTVQIACSVGIVVYPDHGERDKLVANADAA
EEECCCCHHHHHHHHHHHHHHCCCCHHHCCCEEEEEEEEEEEEECCCCCCCCEEECCHHH
MYAAKRAGGNGYAMFESHMDSDATAQLSLQHDLRQAIARGELSLHYQPKIDARRGRINGV
HHHHHHCCCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHH
EALLRWRHPLRGNVSPAEFIPVAERFGLIAQLGNWVIEEACRQMAAWSWDGLRMRVAINL
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
SAYQLRESGLADRIRDALQRHGVPASHLLCEITESVAMEDTRATQRAIEELGRIGVYLSI
HHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEE
DDFGTGYSSLHYLRSLPARQLKIDRSFVRDLEEQEDARAVVDAVVRLAHALGLRVVAEGV
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ETEGQRDILAAMHCDELQGFYFARPMPADTLLAWAVGDKPEGAADFSPSIIDLQALDPSV
CCCCCHHHHHHHHHHHHCCEEEECCCCHHHEEEEECCCCCCCCCCCCCCEEEEEECCCCC
DAPA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]