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The map label for this gene is hcp1 [H]

Identifier: 120610152

GI number: 120610152

Start: 1617808

End: 1618290

Strand: Reverse

Name: hcp1 [H]

Synonym: Aave_1465

Alternate gene names: 120610152

Gene position: 1618290-1617808 (Counterclockwise)

Preceding gene: 120610172

Following gene: 120610151

Centisome position: 30.23

GC content: 60.87

Gene sequence:

>483_bases
ATGTCCGTCGATATGTTCATGAAGGTTGAAGGTGCCAGCGGCGAATCACAAGACGCCAACCACAAGAGCTGGACCGACAT
CCGCTCCTTCACCTGGGGCGCGACGCAACCCAACTCGATGGCCACGGGCAGCGGCGCCGGCGCCGGCAAGGTCACTTTCC
ACGACCTGAACGTCGTGGCCAAGATCGACAAGGCCTACCCGGCCGTGCTCAAGCACTGCTCCTCCGGCAAGCACCTGGGT
CAGGTGGAGATCTCGATGTGCAAGGCCGGCGGCACGCAGATCGAATTCAGCAAGATCACGCTCACCGACGTGCTGGTCAC
GAGCGTCACCGTCAGCGGCACCGACGGCAGCGATGCCGTCCTGGTGAATTACGCATTCCAGGCCGCCAAAATCAAGACCC
AATACTGGGAACAGACGAACCAGGGCGGCAAGGGTGCAGAAAGCTCGGCCGGCTGGAACATCAAGGAAAACAAAGAAGCC
TGA

Upstream 100 bases:

>100_bases
GGCCCCGTTCGTGAGGAACAGGCCACCGCGATGCGAGCGGGTCGGTTCCATTTTTATCTTTCAAAGCGCGTACGCGCAGT
CCATCAAAAGGAAGCATTCC

Downstream 100 bases:

>100_bases
TTCTTCGCTTCGCAAAAGCCGGAGCCTTCACAAAGGCTCCGGCTTTTTTCATGCAATGCATAAATAAATTGCATGCATTC
TCACTGGAACCACCTGCCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MSVDMFMKVEGASGESQDANHKSWTDIRSFTWGATQPNSMATGSGAGAGKVTFHDLNVVAKIDKAYPAVLKHCSSGKHLG
QVEISMCKAGGTQIEFSKITLTDVLVTSVTVSGTDGSDAVLVNYAFQAAKIKTQYWEQTNQGGKGAESSAGWNIKENKEA

Sequences:

>Translated_160_residues
MSVDMFMKVEGASGESQDANHKSWTDIRSFTWGATQPNSMATGSGAGAGKVTFHDLNVVAKIDKAYPAVLKHCSSGKHLG
QVEISMCKAGGTQIEFSKITLTDVLVTSVTVSGTDGSDAVLVNYAFQAAKIKTQYWEQTNQGGKGAESSAGWNIKENKEA
>Mature_159_residues
SVDMFMKVEGASGESQDANHKSWTDIRSFTWGATQPNSMATGSGAGAGKVTFHDLNVVAKIDKAYPAVLKHCSSGKHLGQ
VEISMCKAGGTQIEFSKITLTDVLVTSVTVSGTDGSDAVLVNYAFQAAKIKTQYWEQTNQGGKGAESSAGWNIKENKEA

Specific function: Required for assembly of the protein secretion apparatus HSI-I. Actively secreted during chronic infection of cystic fibrosis patients [H]

COG id: COG3157

COG function: function code S; Hemolysin-coregulated protein (uncharacterized)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hcp1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017728
- InterPro:   IPR008514 [H]

Pfam domain/function: PF05638 DUF796 [H]

EC number: NA

Molecular weight: Translated: 16967; Mature: 16836

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDMFMKVEGASGESQDANHKSWTDIRSFTWGATQPNSMATGSGAGAGKVTFHDLNVVA
CCCEEEEEEECCCCCCCCCCCCCCHHHHHEECCCCCCCCCCCCCCCCCCEEEEEECEEEE
KIDKAYPAVLKHCSSGKHLGQVEISMCKAGGTQIEFSKITLTDVLVTSVTVSGTDGSDAV
EHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEEEEHEEEEEEEEEEECCCCCCEE
LVNYAFQAAKIKTQYWEQTNQGGKGAESSAGWNIKENKEA
EEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVDMFMKVEGASGESQDANHKSWTDIRSFTWGATQPNSMATGSGAGAGKVTFHDLNVVA
CCEEEEEEECCCCCCCCCCCCCCHHHHHEECCCCCCCCCCCCCCCCCCEEEEEECEEEE
KIDKAYPAVLKHCSSGKHLGQVEISMCKAGGTQIEFSKITLTDVLVTSVTVSGTDGSDAV
EHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEEEEHEEEEEEEEEEECCCCCCEE
LVNYAFQAAKIKTQYWEQTNQGGKGAESSAGWNIKENKEA
EEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]