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The map label for this gene is hflX [H]

Identifier: 120610117

GI number: 120610117

Start: 1570670

End: 1571842

Strand: Direct

Name: hflX [H]

Synonym: Aave_1430

Alternate gene names: 120610117

Gene position: 1570670-1571842 (Clockwise)

Preceding gene: 120610116

Following gene: 120610118

Centisome position: 29.34

GC content: 67.18

Gene sequence:

>1173_bases
TTGAGTTCTTCCTCATCCCCTGAACCGCAATCCACTCCCGTCATCCTGGTGGGGGTGGATTTCGGCCTTCCCCATTTCGA
TGCCGAGCTGGAAGAGCTGGGCCTGCTGGCTCAGACCGCGGGCCTCGCGCCCGTGGCCCGGCTGACCTGCAAGCGCAAGG
CGCCCGATGCCGCGCTGTTCGTCGGCAGCGGCAAGGCCGACGAAATCCGCATGCTCGCGCAGATGCACGGCGCGGTGGAG
GTACTGTTCGACCAGGCCCTCAGCCCGGCCCAGCAGCGCAACCTCGAGAGGCATCTCGAGCTGCCGGTCACCGACCGCAC
CCTGCTCATCCTCGAGATCTTCGCGCAACGCGCCCGGAGCCACGAGGGCAAGCTCCAGGTCGAACTCGCCCGTCTGCAAT
ACCTGAGCACCCGCCTCGTGCGCCGCTGGTCCCACCTGGAGCGCCAGCGCGGCGGCATCGGCGCGCGTGGCGGCCCTGGC
GAAACCCAGATCGAGCTCGACCGCCGCATGATCGACGACGCGATCAAGCGCACCCGCGAGCGCCTGCAGAAGGTCAAGCG
CCAGCGCGCCACCCAGCGGCGCCAGCGTGCCCGCCGGGACACCTTCAACATCTCCCTGGTCGGCTACACCAACGCCGGCA
AGTCCACGCTCTTCAACGCGCTCGTGAAGGCGAGGGCCTATGCCGCCGACCAGTTGTTCGCCACGCTGGACACGACCACC
CGCCAGCTGTACCTGGCCGAACTGGGCGGCACCGTGTCCCTGTCCGACACGGTGGGCTTCATCCGCGACCTGCCCCACGG
CCTCATCGATGCCTTCCAGGCCACCCTGCAGGAAGCCGTCGATGCCGACCTGCTCCTGCATGTCGTGGACGCATCCAATC
CCGACTTCCCCGAGCAGATCGCCGAGGTCGAAAAAGTGCTTGGCGAAATCGGGGCCGGTGAGATTCCCCAGGTCCTGATC
TTCAACAAGCTGGATGCCGTGCCCGCCGAACAGCAACCGCTGGCCATGCAGGACACGTACGAATGGGACGGGCGCCAGTT
GCCGAAACTGTTCGTCAGTGCCCGCACCGGGCAGGGGTTGCCTGAACTGCGCAGCCAGTTGACCGCTGCGGCACTGGCCG
CCCGCGAAAACCCCATGACCCCAGGCGCCGATGCTGAATTTCCAGCGCCTTGA

Upstream 100 bases:

>100_bases
TCGACGGCCGAACCCGCGGATGCCGAATCCGGCAATTGACATTCCTGCGCCCGTGTAGGTACACCCTGGACAGGGCGCAT
GCCCCGTCCAGGCTGCTGTC

Downstream 100 bases:

>100_bases
GGCCAGTTGGGCACAATGCCGCGAGACCCATCTTCTCGAAAACTAGAGATCTATCGCATGAATCATCCTTTCAGAGCCTG
GCGTCTGGCATCGCTGCCCG

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSSSSSPEPQSTPVILVGVDFGLPHFDAELEELGLLAQTAGLAPVARLTCKRKAPDAALFVGSGKADEIRMLAQMHGAVE
VLFDQALSPAQQRNLERHLELPVTDRTLLILEIFAQRARSHEGKLQVELARLQYLSTRLVRRWSHLERQRGGIGARGGPG
ETQIELDRRMIDDAIKRTRERLQKVKRQRATQRRQRARRDTFNISLVGYTNAGKSTLFNALVKARAYAADQLFATLDTTT
RQLYLAELGGTVSLSDTVGFIRDLPHGLIDAFQATLQEAVDADLLLHVVDASNPDFPEQIAEVEKVLGEIGAGEIPQVLI
FNKLDAVPAEQQPLAMQDTYEWDGRQLPKLFVSARTGQGLPELRSQLTAAALAARENPMTPGADAEFPAP

Sequences:

>Translated_390_residues
MSSSSSPEPQSTPVILVGVDFGLPHFDAELEELGLLAQTAGLAPVARLTCKRKAPDAALFVGSGKADEIRMLAQMHGAVE
VLFDQALSPAQQRNLERHLELPVTDRTLLILEIFAQRARSHEGKLQVELARLQYLSTRLVRRWSHLERQRGGIGARGGPG
ETQIELDRRMIDDAIKRTRERLQKVKRQRATQRRQRARRDTFNISLVGYTNAGKSTLFNALVKARAYAADQLFATLDTTT
RQLYLAELGGTVSLSDTVGFIRDLPHGLIDAFQATLQEAVDADLLLHVVDASNPDFPEQIAEVEKVLGEIGAGEIPQVLI
FNKLDAVPAEQQPLAMQDTYEWDGRQLPKLFVSARTGQGLPELRSQLTAAALAARENPMTPGADAEFPAP
>Mature_389_residues
SSSSSPEPQSTPVILVGVDFGLPHFDAELEELGLLAQTAGLAPVARLTCKRKAPDAALFVGSGKADEIRMLAQMHGAVEV
LFDQALSPAQQRNLERHLELPVTDRTLLILEIFAQRARSHEGKLQVELARLQYLSTRLVRRWSHLERQRGGIGARGGPGE
TQIELDRRMIDDAIKRTRERLQKVKRQRATQRRQRARRDTFNISLVGYTNAGKSTLFNALVKARAYAADQLFATLDTTTR
QLYLAELGGTVSLSDTVGFIRDLPHGLIDAFQATLQEAVDADLLLHVVDASNPDFPEQIAEVEKVLGEIGAGEIPQVLIF
NKLDAVPAEQQPLAMQDTYEWDGRQLPKLFVSARTGQGLPELRSQLTAAALAARENPMTPGADAEFPAP

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=249, Percent_Identity=37.7510040160643, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI310133116, Length=247, Percent_Identity=38.0566801619433, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI310124269, Length=226, Percent_Identity=38.4955752212389, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI310124267, Length=226, Percent_Identity=38.4955752212389, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI310124171, Length=226, Percent_Identity=38.4955752212389, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI310124169, Length=226, Percent_Identity=38.4955752212389, Blast_Score=126, Evalue=3e-29,
Organism=Escherichia coli, GI1790615, Length=354, Percent_Identity=52.8248587570621, Blast_Score=332, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI17561038, Length=294, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24650079, Length=325, Percent_Identity=34.4615384615385, Blast_Score=121, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 42919; Mature: 42788

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSSSPEPQSTPVILVGVDFGLPHFDAELEELGLLAQTAGLAPVARLTCKRKAPDAALF
CCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEE
VGSGKADEIRMLAQMHGAVEVLFDQALSPAQQRNLERHLELPVTDRTLLILEIFAQRARS
ECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHC
HEGKLQVELARLQYLSTRLVRRWSHLERQRGGIGARGGPGETQIELDRRMIDDAIKRTRE
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RLQKVKRQRATQRRQRARRDTFNISLVGYTNAGKSTLFNALVKARAYAADQLFATLDTTT
HHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQLYLAELGGTVSLSDTVGFIRDLPHGLIDAFQATLQEAVDADLLLHVVDASNPDFPEQI
HHHHHHHCCCEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHEECCCCCCHHHHH
AEVEKVLGEIGAGEIPQVLIFNKLDAVPAEQQPLAMQDTYEWDGRQLPKLFVSARTGQGL
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC
PELRSQLTAAALAARENPMTPGADAEFPAP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSSSSPEPQSTPVILVGVDFGLPHFDAELEELGLLAQTAGLAPVARLTCKRKAPDAALF
CCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEE
VGSGKADEIRMLAQMHGAVEVLFDQALSPAQQRNLERHLELPVTDRTLLILEIFAQRARS
ECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHC
HEGKLQVELARLQYLSTRLVRRWSHLERQRGGIGARGGPGETQIELDRRMIDDAIKRTRE
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RLQKVKRQRATQRRQRARRDTFNISLVGYTNAGKSTLFNALVKARAYAADQLFATLDTTT
HHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQLYLAELGGTVSLSDTVGFIRDLPHGLIDAFQATLQEAVDADLLLHVVDASNPDFPEQI
HHHHHHHCCCEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHEECCCCCCHHHHH
AEVEKVLGEIGAGEIPQVLIFNKLDAVPAEQQPLAMQDTYEWDGRQLPKLFVSARTGQGL
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC
PELRSQLTAAALAARENPMTPGADAEFPAP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]