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The map label for this gene is nuoK

Identifier: 120609960

GI number: 120609960

Start: 1397058

End: 1397366

Strand: Direct

Name: nuoK

Synonym: Aave_1273

Alternate gene names: 120609960

Gene position: 1397058-1397366 (Clockwise)

Preceding gene: 120609959

Following gene: 120609961

Centisome position: 26.1

GC content: 60.52

Gene sequence:

>309_bases
ATGACGTTGACCCTGGGCCATTTCCTGTCGCTGGGCGCGATGCTGTTCGCGCTGTCGGTGATCGGCATCTTCCTGAACCG
CAAGAACCTCATCGTGCTGCTCATGGCCATCGAGCTGATGCTCCTGGCCGTGAACATGAACTTCGTCGCGTTCTCCCACT
ACCTGGGCGACATGCACGGGCAGGTGTTCGTGTTCTTCATCCTGACGGTGGCCGCGGCCGAATCCGCCATCGGCCTCGCG
ATCCTGGTGCTGCTGTTCCGCAACAAGTCCAGCATCGACGCGGAAGATCTCAACACCCTCAAGGGCTGA

Upstream 100 bases:

>100_bases
GCGTGCGCGCCGCCGACCGCGTCGAACTGGTGAAGGTCGCCGCGACGCAGAAGCCCGCGGAAGAAGCGGCGGCCCCCGCA
GCCGCCGAGGAGAAGAAGGC

Downstream 100 bases:

>100_bases
TCCGCCGGTACTTGCAAGGTCTTCAAGAATGAGTCAAACCCTCTCCGCTTCGATGCTCCTCGCGGTGCCGCTGGCGCCGC
TGGCGGGCTCCGCGCTCGCC

Product: NADH-ubiquinone oxidoreductase subunit 4L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit K; NDH-1 subunit K

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MTLTLGHFLSLGAMLFALSVIGIFLNRKNLIVLLMAIELMLLAVNMNFVAFSHYLGDMHGQVFVFFILTVAAAESAIGLA
ILVLLFRNKSSIDAEDLNTLKG

Sequences:

>Translated_102_residues
MTLTLGHFLSLGAMLFALSVIGIFLNRKNLIVLLMAIELMLLAVNMNFVAFSHYLGDMHGQVFVFFILTVAAAESAIGLA
ILVLLFRNKSSIDAEDLNTLKG
>Mature_101_residues
TLTLGHFLSLGAMLFALSVIGIFLNRKNLIVLLMAIELMLLAVNMNFVAFSHYLGDMHGQVFVFFILTVAAAESAIGLAI
LVLLFRNKSSIDAEDLNTLKG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0713

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 4L family

Homologues:

Organism=Escherichia coli, GI1788615, Length=100, Percent_Identity=35, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOK_ACIAC (A1TLM6)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_969638.1
- STRING:   A1TLM6
- GeneID:   4666827
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_1273
- NMPDR:   fig|397945.5.peg.1117
- eggNOG:   COG0713
- HOGENOM:   HBG673066
- OMA:   VLMSIEL
- ProtClustDB:   CLSK732299
- BioCyc:   AAVE397945:AAVE_1273-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01456
- InterPro:   IPR001133

Pfam domain/function: PF00420 Oxidored_q2

EC number: =1.6.99.5

Molecular weight: Translated: 11130; Mature: 10998

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x123d0968)-; HASH(0x12776430)-; HASH(0x12aaff98)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTLGHFLSLGAMLFALSVIGIFLNRKNLIVLLMAIELMLLAVNMNFVAFSHYLGDMHG
CEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
QVFVFFILTVAAAESAIGLAILVLLFRNKSSIDAEDLNTLKG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCH
>Mature Secondary Structure 
TLTLGHFLSLGAMLFALSVIGIFLNRKNLIVLLMAIELMLLAVNMNFVAFSHYLGDMHG
EEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
QVFVFFILTVAAAESAIGLAILVLLFRNKSSIDAEDLNTLKG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA