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The map label for this gene is nuoC

Identifier: 120609952

GI number: 120609952

Start: 1388813

End: 1389421

Strand: Direct

Name: nuoC

Synonym: Aave_1265

Alternate gene names: 120609952

Gene position: 1388813-1389421 (Clockwise)

Preceding gene: 120609951

Following gene: 120609953

Centisome position: 25.95

GC content: 66.5

Gene sequence:

>609_bases
ATGACAGCCATTGCCATCCGACCCGAGGCTCTACGGGACGCGGTCGCCGCTGCGCTCGGCGACAAGGTGCGCGACATCGT
GCTCGCGCTCGACGAACTCACGGTGACCGTCTCGGCCGCCGACTATCTTGCCGCGATGCAGCTGCTGCGCGACGCGCCCG
GCTGCCGGTTCGAGCAGCTCATGGACCTCTGCGGCATCGACTACTCCACCTACGGCGACGTGGGCACGGAAGGCCCGCGC
TATGCGGTCGTGTCGCACCTGCTGTCCGTGAGCCTCAACCAGCGCGTGCGCGTGAAGGTGTTCTGCCCGGACGACGACTT
TCCCGTGGTGGCGTCGGTGTCCGGCATCTGGAACTCCGCCAACTGGTACGAGCGCGAAGCCTTCGACCTGTACGGCATCG
TGTTCGACGGCCATGACGACCTGCGCCGCATCCTGACCGACTACGGCTTCATCGGCCATCCCTTCCGCAAGGATTTCCCG
CTGTCGGGCCACGTCGAGATGCGCTACGACACCGAGGCGCGCCGCGTGGTGTACGAGCCGGTGACGATCGAGCCGCGCGA
GATCACGCCCCGCATCATCCGCGAAGAAAAGTACGGAGGCCTGCACTGA

Upstream 100 bases:

>100_bases
TGCCCCCCGACCGCCGAGGCGCTCATCTACGGGATCATCCAGCTCCAGCAGAAGATCCGCCGCACCCATACCATCGCCCG
CGTCTGAAGGGTTCTCCAGC

Downstream 100 bases:

>100_bases
GGCGCTTCTAGCGCATTCAGGCGATCCACGATGGCTGAAATCAAGAACTACTCCCTGAACTTTGGTCCGCAGCACCCGGC
CGCGCACGGCGTGCTGCGCC

Product: NADH (or F420H2) dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MTAIAIRPEALRDAVAAALGDKVRDIVLALDELTVTVSAADYLAAMQLLRDAPGCRFEQLMDLCGIDYSTYGDVGTEGPR
YAVVSHLLSVSLNQRVRVKVFCPDDDFPVVASVSGIWNSANWYEREAFDLYGIVFDGHDDLRRILTDYGFIGHPFRKDFP
LSGHVEMRYDTEARRVVYEPVTIEPREITPRIIREEKYGGLH

Sequences:

>Translated_202_residues
MTAIAIRPEALRDAVAAALGDKVRDIVLALDELTVTVSAADYLAAMQLLRDAPGCRFEQLMDLCGIDYSTYGDVGTEGPR
YAVVSHLLSVSLNQRVRVKVFCPDDDFPVVASVSGIWNSANWYEREAFDLYGIVFDGHDDLRRILTDYGFIGHPFRKDFP
LSGHVEMRYDTEARRVVYEPVTIEPREITPRIIREEKYGGLH
>Mature_201_residues
TAIAIRPEALRDAVAAALGDKVRDIVLALDELTVTVSAADYLAAMQLLRDAPGCRFEQLMDLCGIDYSTYGDVGTEGPRY
AVVSHLLSVSLNQRVRVKVFCPDDDFPVVASVSGIWNSANWYEREAFDLYGIVFDGHDDLRRILTDYGFIGHPFRKDFPL
SGHVEMRYDTEARRVVYEPVTIEPREITPRIIREEKYGGLH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=175, Percent_Identity=45.1428571428571, Blast_Score=147, Evalue=4e-36,
Organism=Escherichia coli, GI145693162, Length=132, Percent_Identity=36.3636363636364, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71990788, Length=152, Percent_Identity=43.421052631579, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32563621, Length=152, Percent_Identity=43.421052631579, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24656494, Length=170, Percent_Identity=44.7058823529412, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_ACIAC (A1TLL8)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_969630.1
- ProteinModelPortal:   A1TLL8
- SMR:   A1TLL8
- STRING:   A1TLL8
- GeneID:   4669087
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_1265
- NMPDR:   fig|397945.5.peg.1109
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   VFAPDDD
- ProtClustDB:   CLSK963010
- BioCyc:   AAVE397945:AAVE_1265-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 22756; Mature: 22625

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIAIRPEALRDAVAAALGDKVRDIVLALDELTVTVSAADYLAAMQLLRDAPGCRFEQL
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHCCCCCCHHHH
MDLCGIDYSTYGDVGTEGPRYAVVSHLLSVSLNQRVRVKVFCPDDDFPVVASVSGIWNSA
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECCCCCCC
NWYEREAFDLYGIVFDGHDDLRRILTDYGFIGHPFRKDFPLSGHVEMRYDTEARRVVYEP
CCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEECC
VTIEPREITPRIIREEKYGGLH
CCCCCHHCCHHHHHHCCCCCCC
>Mature Secondary Structure 
TAIAIRPEALRDAVAAALGDKVRDIVLALDELTVTVSAADYLAAMQLLRDAPGCRFEQL
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHCCCCCCHHHH
MDLCGIDYSTYGDVGTEGPRYAVVSHLLSVSLNQRVRVKVFCPDDDFPVVASVSGIWNSA
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECCCCCCC
NWYEREAFDLYGIVFDGHDDLRRILTDYGFIGHPFRKDFPLSGHVEMRYDTEARRVVYEP
CCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEECC
VTIEPREITPRIIREEKYGGLH
CCCCCHHCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA