Click here to switch to the map view.

The map label for this gene is nuoA

Identifier: 120609950

GI number: 120609950

Start: 1387936

End: 1388295

Strand: Direct

Name: nuoA

Synonym: Aave_1263

Alternate gene names: 120609950

Gene position: 1387936-1388295 (Clockwise)

Preceding gene: 120609949

Following gene: 120609951

Centisome position: 25.93

GC content: 60.28

Gene sequence:

>360_bases
ATGAACCTCGATCAATACCTCCCCGTTCTTCTGTTCATCCTGGTCGGCATCGGAGTGGGGGTGGTGCCCCTGGTCCTGGG
CTACGTGCTGGGACCCAACCGGCCCGACGCGGCCAAGAACTCCCCCTACGAGTGTGGCTTCGAGGCCTTCGAAGATGCGC
GCATGAAGTTCGACGTGCGCTACTACCTCGTCGCCATCCTCTTCATTCTTTTCGATCTGGAAATCGCATTCCTCTTCCCG
TGGGCGGTCGCGCTGCACGAGGTGGGGATGACCGGTTTCGTCGCCGTCATCGTCTTCCTGGCCATCCTGGTCGTGGGCTT
CGCCTACGAGTGGAAAAAGGGTGCCCTGGATTGGGAATGA

Upstream 100 bases:

>100_bases
GTTCGAGTCTCGCCGACGGCACCAACACACAAGCAAGCCCGCCCGGCCATTCCTCATCGCAGGAATGGGGGTGCGGCCCC
AGCGGTGAGTACCCCTCCAG

Downstream 100 bases:

>100_bases
CGGGGCTTCACAAGGAACGACACGATGATTGAAGGCGTGATGAAGGAAGGCTTCATCACCACGAGCTATGACTCCGTGGT
GAACTGGGCCAAGACCGGAT

Product: NADH-ubiquinone/plastoquinone oxidoreductase subunit 3

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MNLDQYLPVLLFILVGIGVGVVPLVLGYVLGPNRPDAAKNSPYECGFEAFEDARMKFDVRYYLVAILFILFDLEIAFLFP
WAVALHEVGMTGFVAVIVFLAILVVGFAYEWKKGALDWE

Sequences:

>Translated_119_residues
MNLDQYLPVLLFILVGIGVGVVPLVLGYVLGPNRPDAAKNSPYECGFEAFEDARMKFDVRYYLVAILFILFDLEIAFLFP
WAVALHEVGMTGFVAVIVFLAILVVGFAYEWKKGALDWE
>Mature_119_residues
MNLDQYLPVLLFILVGIGVGVVPLVLGYVLGPNRPDAAKNSPYECGFEAFEDARMKFDVRYYLVAILFILFDLEIAFLFP
WAVALHEVGMTGFVAVIVFLAILVVGFAYEWKKGALDWE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=108, Percent_Identity=37.962962962963, Blast_Score=89, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_ACIAC (A1TLL6)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_969628.1
- STRING:   A1TLL6
- GeneID:   4665551
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_1263
- NMPDR:   fig|397945.5.peg.1107
- eggNOG:   COG0838
- HOGENOM:   HBG605540
- OMA:   IGFAYEW
- PhylomeDB:   A1TLL6
- ProtClustDB:   CLSK963009
- BioCyc:   AAVE397945:AAVE_1263-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 13351; Mature: 13351

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11d21574)-; HASH(0x124f3514)-; HASH(0x110d2490)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDQYLPVLLFILVGIGVGVVPLVLGYVLGPNRPDAAKNSPYECGFEAFEDARMKFDVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
YYLVAILFILFDLEIAFLFPWAVALHEVGMTGFVAVIVFLAILVVGFAYEWKKGALDWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MNLDQYLPVLLFILVGIGVGVVPLVLGYVLGPNRPDAAKNSPYECGFEAFEDARMKFDVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
YYLVAILFILFDLEIAFLFPWAVALHEVGMTGFVAVIVFLAILVVGFAYEWKKGALDWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA