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The map label for this gene is asd [H]

Identifier: 120609906

GI number: 120609906

Start: 1343400

End: 1344530

Strand: Reverse

Name: asd [H]

Synonym: Aave_1219

Alternate gene names: 120609906

Gene position: 1344530-1343400 (Counterclockwise)

Preceding gene: 120609907

Following gene: 120609905

Centisome position: 25.12

GC content: 66.93

Gene sequence:

>1131_bases
ATGAGCAAGTTGGTAGGGTTGGTCGGCTGGCGCGGCATGGTCGGCTCGGTCCTGATGGAGCGCATGGAGGCCGAGGGCGA
TTTCGGCCTCATCGAGCCGCTTTTCTTCTCCACCTCGAACGCGGGCGGCAAGGCTCCGGCGCAGGCGAAGAACGAAACCA
CGCTGCAGGATGCGTTCGACATCAACGCCCTCAAGCGCTGCGACATCATCCTCACCGCCCAGGGCGGCGACTACACGAGC
GAAGTGTTCCCCAAGCTGCGCGATGCCGGCTGGAAGGGCCACTGGATCGACGCCGCCTCCACGCTGCGCATGAAGGACGA
TGCCGTGATCGTGCTCGATCCGGTGAACATGCCCGTCATCAAGGATGCACTCGCCAAGGGCGGCAACAACTGGATCGGCG
GCAACTGCACCGTGAGCTGCATGCTGATGGGCGTGGGCGCGCTCTACAAGGCCGGCCTCGTCGAGTGGATGAGCACCCAG
ACCTACCAGGCGGCCAGCGGCGGCGGCGCGCAGCACATGCGCGAGCTGCTCACGCAGTACGGCACGCTGAATGCCGAAGT
GCGCTCGCTGCTCGACGATCCGAAGAGCGCCATCCTGGAGATCGACCGCAAGGTCATCGCCAGGCAGCGCAGCCTCTCCG
AGGCCGAGACCGCCAACTTCGGCGTGCCGCTGGGCGGCAGCCTGATCCCCTGGATCGACAAGGACCTGGGCAACGGCATG
TCGAAGGAAGAGTGGAAGGGCATGGCCGAGACCAACAAGATCCTCGGCCAGGGCGAAGGCTTCGGCACCCAGGCCGTGCC
GGTGGACGGCTTCTGCGTGCGCGTGGGCGCCATGCGCTGCCACAGCCAGGCACTGACCTTGAAGCTGAAGAAGCACGTGC
CCGTGGCCGACATCGAGGCCATGATCGCCGCCGACAACGAGTGGGTGAAAGTGGTGCCGAACACGCGCGAAGCCACGCTC
CGTGACCTGACGCCCGTCGCCGTGACCGGCACCATGACCATCCCGGTCGGCCGCATCCGCCAGCTCGCCATGGGCCCGGA
CTACATCGGCGCCTTCACCATCGGGGACCAGCTGCTGTGGGGCGCCGCCGAGCCGCTGCGCCGCATGCTGCGCATCCTGC
TGGACGCCTGA

Upstream 100 bases:

>100_bases
GCTGATCCAGCCTGGTTCGTCGTGCGCCCTTCCTGGCCCTGACGAGCCAGGCGAGCAGTCCCGGTCGGGTACTGTTTTCT
TAAACCGAAAGGGCGTTGAA

Downstream 100 bases:

>100_bases
ACGCAGCGTCTTCCTGCCCGGGCTGACGTAACCGGGATACAGGATTCACGCACGCTTTGTTACGAGTCGTTGTCCTACGA
CAACATGCAAAAACAGTCTC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSKLVGLVGWRGMVGSVLMERMEAEGDFGLIEPLFFSTSNAGGKAPAQAKNETTLQDAFDINALKRCDIILTAQGGDYTS
EVFPKLRDAGWKGHWIDAASTLRMKDDAVIVLDPVNMPVIKDALAKGGNNWIGGNCTVSCMLMGVGALYKAGLVEWMSTQ
TYQAASGGGAQHMRELLTQYGTLNAEVRSLLDDPKSAILEIDRKVIARQRSLSEAETANFGVPLGGSLIPWIDKDLGNGM
SKEEWKGMAETNKILGQGEGFGTQAVPVDGFCVRVGAMRCHSQALTLKLKKHVPVADIEAMIAADNEWVKVVPNTREATL
RDLTPVAVTGTMTIPVGRIRQLAMGPDYIGAFTIGDQLLWGAAEPLRRMLRILLDA

Sequences:

>Translated_376_residues
MSKLVGLVGWRGMVGSVLMERMEAEGDFGLIEPLFFSTSNAGGKAPAQAKNETTLQDAFDINALKRCDIILTAQGGDYTS
EVFPKLRDAGWKGHWIDAASTLRMKDDAVIVLDPVNMPVIKDALAKGGNNWIGGNCTVSCMLMGVGALYKAGLVEWMSTQ
TYQAASGGGAQHMRELLTQYGTLNAEVRSLLDDPKSAILEIDRKVIARQRSLSEAETANFGVPLGGSLIPWIDKDLGNGM
SKEEWKGMAETNKILGQGEGFGTQAVPVDGFCVRVGAMRCHSQALTLKLKKHVPVADIEAMIAADNEWVKVVPNTREATL
RDLTPVAVTGTMTIPVGRIRQLAMGPDYIGAFTIGDQLLWGAAEPLRRMLRILLDA
>Mature_375_residues
SKLVGLVGWRGMVGSVLMERMEAEGDFGLIEPLFFSTSNAGGKAPAQAKNETTLQDAFDINALKRCDIILTAQGGDYTSE
VFPKLRDAGWKGHWIDAASTLRMKDDAVIVLDPVNMPVIKDALAKGGNNWIGGNCTVSCMLMGVGALYKAGLVEWMSTQT
YQAASGGGAQHMRELLTQYGTLNAEVRSLLDDPKSAILEIDRKVIARQRSLSEAETANFGVPLGGSLIPWIDKDLGNGMS
KEEWKGMAETNKILGQGEGFGTQAVPVDGFCVRVGAMRCHSQALTLKLKKHVPVADIEAMIAADNEWVKVVPNTREATLR
DLTPVAVTGTMTIPVGRIRQLAMGPDYIGAFTIGDQLLWGAAEPLRRMLRILLDA

Specific function: Second step in the common biosynthetic pathway leading from Asp to the cell wall precursor meso-diaminopimelate, to Lys, to Met, to Ile and to Thr. [C]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789841, Length=371, Percent_Identity=63.8814016172507, Blast_Score=486, Evalue=1e-138,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR011534
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 40577; Mature: 40446

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLVGLVGWRGMVGSVLMERMEAEGDFGLIEPLFFSTSNAGGKAPAQAKNETTLQDAFD
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEECCCCCCCCCCCCCCCCHHHHHHC
INALKRCDIILTAQGGDYTSEVFPKLRDAGWKGHWIDAASTLRMKDDAVIVLDPVNMPVI
CCHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCEEECCCCEEEECCCEEEEECCCCCHHH
KDALAKGGNNWIGGNCTVSCMLMGVGALYKAGLVEWMSTQTYQAASGGGAQHMRELLTQY
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHH
GTLNAEVRSLLDDPKSAILEIDRKVIARQRSLSEAETANFGVPLGGSLIPWIDKDLGNGM
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCC
SKEEWKGMAETNKILGQGEGFGTQAVPVDGFCVRVGAMRCHSQALTLKLKKHVPVADIEA
CHHHHCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHEEEEEECCCCHHHHHH
MIAADNEWVKVVPNTREATLRDLTPVAVTGTMTIPVGRIRQLAMGPDYIGAFTIGDQLLW
EEECCCCEEEECCCCCHHHHHCCCCEEEEEEEECCHHHHHHHHCCCCCCEEEECCCHHHH
GAAEPLRRMLRILLDA
CCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKLVGLVGWRGMVGSVLMERMEAEGDFGLIEPLFFSTSNAGGKAPAQAKNETTLQDAFD
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEECCCCCCCCCCCCCCCCHHHHHHC
INALKRCDIILTAQGGDYTSEVFPKLRDAGWKGHWIDAASTLRMKDDAVIVLDPVNMPVI
CCHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCEEECCCCEEEECCCEEEEECCCCCHHH
KDALAKGGNNWIGGNCTVSCMLMGVGALYKAGLVEWMSTQTYQAASGGGAQHMRELLTQY
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHH
GTLNAEVRSLLDDPKSAILEIDRKVIARQRSLSEAETANFGVPLGGSLIPWIDKDLGNGM
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCC
SKEEWKGMAETNKILGQGEGFGTQAVPVDGFCVRVGAMRCHSQALTLKLKKHVPVADIEA
CHHHHCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHEEEEEECCCCHHHHHH
MIAADNEWVKVVPNTREATLRDLTPVAVTGTMTIPVGRIRQLAMGPDYIGAFTIGDQLLW
EEECCCCEEEECCCCCHHHHHCCCCEEEEEEEECCHHHHHHHHCCCCCCEEEECCCHHHH
GAAEPLRRMLRILLDA
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]