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The map label for this gene is pdxJ [H]

Identifier: 120609887

GI number: 120609887

Start: 1319457

End: 1320233

Strand: Direct

Name: pdxJ [H]

Synonym: Aave_1199

Alternate gene names: 120609887

Gene position: 1319457-1320233 (Clockwise)

Preceding gene: 120609886

Following gene: 120609888

Centisome position: 24.65

GC content: 71.69

Gene sequence:

>777_bases
ATGACCCAGCATTCCGTGCGTACTGCCCTGTCGGTGAACGTCAACAAGGTGGCCCTGGTGCGCAACACGCGCCACCTGGG
CATTCCCAGCGTGGAGCGCGCCGCGCTGCGGTGCCTGGAGGCGGGCGCGCAGGGCATCACCATCCATCCGCGCCCGGACG
GGCGCCACATCCGGGCGGACGACGTGCCCGTGCTGGCTGCGCTGCTGCGCCAGTGGCCGGACCGCGAGTTCAACATCGAG
GGCAATCCGTCGCAGAACCTCATGGAGTTCATCTGCGCCGTGCGTCCGCACCAGGCCACCTTCGTGCCGGACGGCGAGGA
CCAGTTCACCAGCGACCACGGCTGGAGCTTTCCGCAGGACGCCGAGCGCCTGGCGCCCCTGGTGGCCGAATGCCGCGGGC
TGGGCGTGCGCGTGAGCCTGTTCATGGATGCGGAGCCGGCGCAGATGGCCGCCGCGCGTGCCGTGGGAGCCGACCGCGTG
GAGCTCTACACCGAACCCTATGCCGCGGCCTGGGGCACGCCTGCGCAGGAGGCGCAGCTCGTGCGCTACGCGGATGCGGC
CCGGGCGGCGCTGGAGGCCGGGCTGGGCGTGAACGCCGGGCACGATCTCAACCGGGACAATCTCGCGGCCTTCGTGGCAC
GCGTGCCGGGCCTGATGGAGGTGTCGATCGGGCATGCCTTCGTCGCGGATGCGCTGGAACTGGGCTACGCCGCCGCCGTG
CAGGCCTACCAGCGCTGCATCGATGCCGGCATGGCGCAGCGGCAGGCCGGCGCATGA

Upstream 100 bases:

>100_bases
CGGCCGCGGATCTCAAGCCGCAGCTGCGTGCTCTGCTGCAATACCATTGCGGCAGTCCAATGCTGCGGACGCGGCAGCTC
ATGATCGATCTCCAATCCCT

Downstream 100 bases:

>100_bases
TCTACGGCATCGGTACCGACATCTGCGATGTCCGCCGCATCCGGGCGGGCCTGGAGCGCCATGGGGACCGTTTCGCCGAA
AAGGTGCTCGCGGCCGGCGA

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTQHSVRTALSVNVNKVALVRNTRHLGIPSVERAALRCLEAGAQGITIHPRPDGRHIRADDVPVLAALLRQWPDREFNIE
GNPSQNLMEFICAVRPHQATFVPDGEDQFTSDHGWSFPQDAERLAPLVAECRGLGVRVSLFMDAEPAQMAAARAVGADRV
ELYTEPYAAAWGTPAQEAQLVRYADAARAALEAGLGVNAGHDLNRDNLAAFVARVPGLMEVSIGHAFVADALELGYAAAV
QAYQRCIDAGMAQRQAGA

Sequences:

>Translated_258_residues
MTQHSVRTALSVNVNKVALVRNTRHLGIPSVERAALRCLEAGAQGITIHPRPDGRHIRADDVPVLAALLRQWPDREFNIE
GNPSQNLMEFICAVRPHQATFVPDGEDQFTSDHGWSFPQDAERLAPLVAECRGLGVRVSLFMDAEPAQMAAARAVGADRV
ELYTEPYAAAWGTPAQEAQLVRYADAARAALEAGLGVNAGHDLNRDNLAAFVARVPGLMEVSIGHAFVADALELGYAAAV
QAYQRCIDAGMAQRQAGA
>Mature_257_residues
TQHSVRTALSVNVNKVALVRNTRHLGIPSVERAALRCLEAGAQGITIHPRPDGRHIRADDVPVLAALLRQWPDREFNIEG
NPSQNLMEFICAVRPHQATFVPDGEDQFTSDHGWSFPQDAERLAPLVAECRGLGVRVSLFMDAEPAQMAAARAVGADRVE
LYTEPYAAAWGTPAQEAQLVRYADAARAALEAGLGVNAGHDLNRDNLAAFVARVPGLMEVSIGHAFVADALELGYAAAVQ
AYQRCIDAGMAQRQAGA

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=238, Percent_Identity=34.8739495798319, Blast_Score=134, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 27781; Mature: 27649

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQHSVRTALSVNVNKVALVRNTRHLGIPSVERAALRCLEAGAQGITIHPRPDGRHIRAD
CCCHHHHHHEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCEECCC
DVPVLAALLRQWPDREFNIEGNPSQNLMEFICAVRPHQATFVPDGEDQFTSDHGWSFPQD
CHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCHH
AERLAPLVAECRGLGVRVSLFMDAEPAQMAAARAVGADRVELYTEPYAAAWGTPAQEAQL
HHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEECCHHHHCCCCHHHHHH
VRYADAARAALEAGLGVNAGHDLNRDNLAAFVARVPGLMEVSIGHAFVADALELGYAAAV
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHH
QAYQRCIDAGMAQRQAGA
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQHSVRTALSVNVNKVALVRNTRHLGIPSVERAALRCLEAGAQGITIHPRPDGRHIRAD
CCHHHHHHEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCEECCC
DVPVLAALLRQWPDREFNIEGNPSQNLMEFICAVRPHQATFVPDGEDQFTSDHGWSFPQD
CHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCHH
AERLAPLVAECRGLGVRVSLFMDAEPAQMAAARAVGADRVELYTEPYAAAWGTPAQEAQL
HHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEECCHHHHCCCCHHHHHH
VRYADAARAALEAGLGVNAGHDLNRDNLAAFVARVPGLMEVSIGHAFVADALELGYAAAV
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHH
QAYQRCIDAGMAQRQAGA
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA