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The map label for this gene is mucB [H]

Identifier: 120609879

GI number: 120609879

Start: 1310307

End: 1311365

Strand: Direct

Name: mucB [H]

Synonym: Aave_1191

Alternate gene names: 120609879

Gene position: 1310307-1311365 (Clockwise)

Preceding gene: 120609878

Following gene: 120609880

Centisome position: 24.48

GC content: 70.35

Gene sequence:

>1059_bases
ATGGCGGTGCCGGCCCTTGCGGCGCTGCTGGCGGGCGCGCCGTGGTACGCCGCCTGGGCAGCGTCCGGAGAGGGCACCTC
GGGCAATCCGGTCCCCTCCGTTGCGGCGCATGCATCCGCGTCCCAGGCCCAGGCCCAGGCCCAGGCGGAAATCGAGGACT
GGGTGGAGCGCATCCACCGGGCATCGCGCGAGCAGAGCTATCGCGGCAGCTTCGTGGTGTGGTCTTCCGCGGGGGGCATG
ACCAGTTCCCGCATCTGGCACGCGACGGACGGCAAGGTGCAGATCGAGCGCATCGAGGCCCTGGATGGCTCGCCGCGCAC
CGTATTCCGCAAGGACGATCTGGTACGCACTTTCCTGCCGAAGGCCCGGGTGGTGAAGGAAGAGCGGCGGGACATGCCGG
GCCTGTTCCCCCATCTGCCGCAGGCCGAAAGCAGCGCGGTGCTGCGCCATTACCGGGCCCGGTTCCTCGGCAGCGACCGG
GTGGCGGGGCAGGATGCCAGCATCCTGTGGCTGGAGCCCCGGGACGGATTGCGCTTCGGCTACCGCATCTGGATGGCGCG
GCCCAGCGGCCTGGTTGTCAAGCTGCAGACGCTGGGTCTGCGTGGCCAGGTGCTGGAGCAGGCGGCGTTCTCGCAGATCG
ACTTCGATACACCTCCCACCGTGCCGCAACTGGCGGCGCAGATGGACGATACCCGCGGGTTCCGGCTGCTGGCCGTTCCG
CTGGTGAAGACGACGGCGCGGGAGGCCGGCTGGCAGCTGAGCCGGCCCGTGGCCGGGTTTGTCCCCGGCGATTGCTACAA
GCGGGATCCGGCCGTGCTGGCCAGGATGCCCATGCCCCCCCTGCAGTGCATCTTCTCGGACGGCCTGGCAACGGTGTCGC
TGTTCTTCGAGCCCTACGACGCCGCGCGCCATGCCGGCGAGCCGCGCCGCATGGACATGGGTGCCACCCAGACCCTCGCC
CAGCGGGTGGCCGGAGGCTCCATCTGGCTCACCGCCGTGGGCGAAGTGCCGCAGGAAACCCTGCGGCAACTGGTCGAGCA
GATCGAACCCGTGCGCTGA

Upstream 100 bases:

>100_bases
CGCTGAGCGCTTGCACTACCGGAGATCGGGATTGGCAGGTCCGAGGAACGCCGACGGCTGGGTGCCGCGATTCCAGCACG
GCCGTTGTTGGGTGAGGACG

Downstream 100 bases:

>100_bases
ACCGGGCGCGCGGCCGGTGGAATGCCGCCGCGGCGCAGGGAACCAAACACGGCCTTGTCCTTCACACCTTCGCATGCGTT
TTTGCACAACATCGGCGATT

Product: putative sigma E regulatory protein, MucB/RseB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MAVPALAALLAGAPWYAAWAASGEGTSGNPVPSVAAHASASQAQAQAQAEIEDWVERIHRASREQSYRGSFVVWSSAGGM
TSSRIWHATDGKVQIERIEALDGSPRTVFRKDDLVRTFLPKARVVKEERRDMPGLFPHLPQAESSAVLRHYRARFLGSDR
VAGQDASILWLEPRDGLRFGYRIWMARPSGLVVKLQTLGLRGQVLEQAAFSQIDFDTPPTVPQLAAQMDDTRGFRLLAVP
LVKTTAREAGWQLSRPVAGFVPGDCYKRDPAVLARMPMPPLQCIFSDGLATVSLFFEPYDAARHAGEPRRMDMGATQTLA
QRVAGGSIWLTAVGEVPQETLRQLVEQIEPVR

Sequences:

>Translated_352_residues
MAVPALAALLAGAPWYAAWAASGEGTSGNPVPSVAAHASASQAQAQAQAEIEDWVERIHRASREQSYRGSFVVWSSAGGM
TSSRIWHATDGKVQIERIEALDGSPRTVFRKDDLVRTFLPKARVVKEERRDMPGLFPHLPQAESSAVLRHYRARFLGSDR
VAGQDASILWLEPRDGLRFGYRIWMARPSGLVVKLQTLGLRGQVLEQAAFSQIDFDTPPTVPQLAAQMDDTRGFRLLAVP
LVKTTAREAGWQLSRPVAGFVPGDCYKRDPAVLARMPMPPLQCIFSDGLATVSLFFEPYDAARHAGEPRRMDMGATQTLA
QRVAGGSIWLTAVGEVPQETLRQLVEQIEPVR
>Mature_351_residues
AVPALAALLAGAPWYAAWAASGEGTSGNPVPSVAAHASASQAQAQAQAEIEDWVERIHRASREQSYRGSFVVWSSAGGMT
SSRIWHATDGKVQIERIEALDGSPRTVFRKDDLVRTFLPKARVVKEERRDMPGLFPHLPQAESSAVLRHYRARFLGSDRV
AGQDASILWLEPRDGLRFGYRIWMARPSGLVVKLQTLGLRGQVLEQAAFSQIDFDTPPTVPQLAAQMDDTRGFRLLAVPL
VKTTAREAGWQLSRPVAGFVPGDCYKRDPAVLARMPMPPLQCIFSDGLATVSLFFEPYDAARHAGEPRRMDMGATQTLAQ
RVAGGSIWLTAVGEVPQETLRQLVEQIEPVR

Specific function: Negative regulator of the sigma factor AlgU. Plays a role in the differentiation of P.aeruginosa into the alginate- producing form. Inactivation of mucB causes conversion to mucoidy [H]

COG id: COG3026

COG function: function code T; Negative regulator of sigma E activity

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rseB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005588 [H]

Pfam domain/function: PF03888 MucB_RseB [H]

EC number: NA

Molecular weight: Translated: 38635; Mature: 38504

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVPALAALLAGAPWYAAWAASGEGTSGNPVPSVAAHASASQAQAQAQAEIEDWVERIHR
CCHHHHHHHHCCCCHHEEEECCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ASREQSYRGSFVVWSSAGGMTSSRIWHATDGKVQIERIEALDGSPRTVFRKDDLVRTFLP
HHHHHCCCCCEEEEECCCCCCCCEEEECCCCEEEEEEEECCCCCCCEEECHHHHHHHHCC
KARVVKEERRDMPGLFPHLPQAESSAVLRHYRARFLGSDRVAGQDASILWLEPRDGLRFG
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEE
YRIWMARPSGLVVKLQTLGLRGQVLEQAAFSQIDFDTPPTVPQLAAQMDDTRGFRLLAVP
EEEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEEH
LVKTTAREAGWQLSRPVAGFVPGDCYKRDPAVLARMPMPPLQCIFSDGLATVSLFFEPYD
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHEECCCCCHHHHHHHCCCEEEEEEECCHH
AARHAGEPRRMDMGATQTLAQRVAGGSIWLTAVGEVPQETLRQLVEQIEPVR
HHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVPALAALLAGAPWYAAWAASGEGTSGNPVPSVAAHASASQAQAQAQAEIEDWVERIHR
CHHHHHHHHCCCCHHEEEECCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ASREQSYRGSFVVWSSAGGMTSSRIWHATDGKVQIERIEALDGSPRTVFRKDDLVRTFLP
HHHHHCCCCCEEEEECCCCCCCCEEEECCCCEEEEEEEECCCCCCCEEECHHHHHHHHCC
KARVVKEERRDMPGLFPHLPQAESSAVLRHYRARFLGSDRVAGQDASILWLEPRDGLRFG
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEE
YRIWMARPSGLVVKLQTLGLRGQVLEQAAFSQIDFDTPPTVPQLAAQMDDTRGFRLLAVP
EEEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEEH
LVKTTAREAGWQLSRPVAGFVPGDCYKRDPAVLARMPMPPLQCIFSDGLATVSLFFEPYD
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHEECCCCCHHHHHHHCCCEEEEEEECCHH
AARHAGEPRRMDMGATQTLAQRVAGGSIWLTAVGEVPQETLRQLVEQIEPVR
HHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8412698; 8378309; 8444793; 10984043 [H]