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The map label for this gene is degU [H]

Identifier: 120609812

GI number: 120609812

Start: 1228695

End: 1229363

Strand: Reverse

Name: degU [H]

Synonym: Aave_1121

Alternate gene names: 120609812

Gene position: 1229363-1228695 (Counterclockwise)

Preceding gene: 120609813

Following gene: 120609811

Centisome position: 22.97

GC content: 72.05

Gene sequence:

>669_bases
ATGAACGCCGACCCCGGCCAGACCCCGATCCGCGTCCTGCTGGTGGACGACCATCCGCTGGTGCGCGACGGCGTGCGCAT
GCGCCTGGACGCCACGCCCCACATCCGCGTGGCCGCCGAGGCGGGCGGCGTGCAGGAGGCCCTCGCACTTGCCGAGGCCG
TGGCGCCGGACATCGTGCTGACCGACATCCGCATGCCCGACGGCAGCGGCATCCAGTTGGCGGCGCTGTTCCGTGAACGC
TTTCCGCTGGTGCGCGTGATGGTGCTGTCGATGCACCAGGATGCCGAGTACGTGCGGCGTGCCGTGGGCCTGGGCGTGCG
CGGCTACGTGCTCAAGGACGCGCCGGCCGGCCAGCTGGTGCAGGCCATCGAGACGGTGCGGGCGGGCGGCAGCCATTTCA
GCGAAGCCGTGCGCGCGCTGGTGGACGGCGGGCAGCCGGCGCCACCCCAGGGGCGGTCGCTCACGCCGCGCGAGGCGGTG
GTGCTCCGGCTGCTCGCGGAAGGGCGATCCAACAAGGACATCGCCGAACGGATGGGTACTTCGGTGCGCACCGTGGAAAC
ACACCGCCTGCACCTGCGGCGCAAGCTGCGCATCGATGGGCAGGCGGCCCTGGTCAAGTACGCCGTGGCCTATGCGGACC
TCCGCTGCGATCCGCACCTGCCGACCTGA

Upstream 100 bases:

>100_bases
CATCGGGCCGCGGCGGCACGCGCATCCTGGCGGTGCTCGACCGCCGGGACGCGCCCGCCGCCGGGCTGTCCGCCGGCATC
GAACCCTCGCAGGTGCCCGC

Downstream 100 bases:

>100_bases
ATGGCACTGCCAGCCACCGTTTTCGCGCAGCCGTGCGGGCCGCTCCTGACGGGATTCCCCGCTGCGGGACGGACCGTGTC
ATTCCGACGTCATGCGAAGG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MNADPGQTPIRVLLVDDHPLVRDGVRMRLDATPHIRVAAEAGGVQEALALAEAVAPDIVLTDIRMPDGSGIQLAALFRER
FPLVRVMVLSMHQDAEYVRRAVGLGVRGYVLKDAPAGQLVQAIETVRAGGSHFSEAVRALVDGGQPAPPQGRSLTPREAV
VLRLLAEGRSNKDIAERMGTSVRTVETHRLHLRRKLRIDGQAALVKYAVAYADLRCDPHLPT

Sequences:

>Translated_222_residues
MNADPGQTPIRVLLVDDHPLVRDGVRMRLDATPHIRVAAEAGGVQEALALAEAVAPDIVLTDIRMPDGSGIQLAALFRER
FPLVRVMVLSMHQDAEYVRRAVGLGVRGYVLKDAPAGQLVQAIETVRAGGSHFSEAVRALVDGGQPAPPQGRSLTPREAV
VLRLLAEGRSNKDIAERMGTSVRTVETHRLHLRRKLRIDGQAALVKYAVAYADLRCDPHLPT
>Mature_222_residues
MNADPGQTPIRVLLVDDHPLVRDGVRMRLDATPHIRVAAEAGGVQEALALAEAVAPDIVLTDIRMPDGSGIQLAALFRER
FPLVRVMVLSMHQDAEYVRRAVGLGVRGYVLKDAPAGQLVQAIETVRAGGSHFSEAVRALVDGGQPAPPQGRSLTPREAV
VLRLLAEGRSNKDIAERMGTSVRTVETHRLHLRRKLRIDGQAALVKYAVAYADLRCDPHLPT

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=204, Percent_Identity=35.2941176470588, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1790102, Length=197, Percent_Identity=32.994923857868, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788712, Length=199, Percent_Identity=28.643216080402, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1787473, Length=188, Percent_Identity=34.5744680851064, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788222, Length=204, Percent_Identity=28.921568627451, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788546, Length=201, Percent_Identity=26.865671641791, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=23.4146341463415, Blast_Score=87, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24088; Mature: 24088

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNADPGQTPIRVLLVDDHPLVRDGVRMRLDATPHIRVAAEAGGVQEALALAEAVAPDIVL
CCCCCCCCCEEEEEECCCCCHHCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHCCCEEE
TDIRMPDGSGIQLAALFRERFPLVRVMVLSMHQDAEYVRRAVGLGVRGYVLKDAPAGQLV
EEEECCCCCCCHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCCHHHHH
QAIETVRAGGSHFSEAVRALVDGGQPAPPQGRSLTPREAVVLRLLAEGRSNKDIAERMGT
HHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCC
SVRTVETHRLHLRRKLRIDGQAALVKYAVAYADLRCDPHLPT
CEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNADPGQTPIRVLLVDDHPLVRDGVRMRLDATPHIRVAAEAGGVQEALALAEAVAPDIVL
CCCCCCCCCEEEEEECCCCCHHCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHCCCEEE
TDIRMPDGSGIQLAALFRERFPLVRVMVLSMHQDAEYVRRAVGLGVRGYVLKDAPAGQLV
EEEECCCCCCCHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCCHHHHH
QAIETVRAGGSHFSEAVRALVDGGQPAPPQGRSLTPREAVVLRLLAEGRSNKDIAERMGT
HHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCC
SVRTVETHRLHLRRKLRIDGQAALVKYAVAYADLRCDPHLPT
CEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]