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The map label for this gene is ttuD [H]

Identifier: 120609804

GI number: 120609804

Start: 1218718

End: 1220064

Strand: Direct

Name: ttuD [H]

Synonym: Aave_1113

Alternate gene names: 120609804

Gene position: 1218718-1220064 (Clockwise)

Preceding gene: 120609799

Following gene: 120609807

Centisome position: 22.77

GC content: 74.91

Gene sequence:

>1347_bases
ATGACACTGCCCGCCCTGCCGCCTGCATCTGCCCCGTCGCCCGCGCCGGATCCCGCCGCAGATCCCACGCGCTTCCTGCG
CCACCTCTATGGCGTGGCCGTGCAGGCGGCCCTGCCCTCGGTGCGCCTGGCCGCGCACCTGCCCGCGCCGCCGCGGGGCC
GCACGCTGGTGCTGGGGGCCGGCAAGGCCGGGGCCTCGATGGTGCATGCGCTGGAGGCGCTGTGGCCGGCCGAAGCGCCG
CTCTCCGGTCTGGTCGTGACGCGCTACGGCCATGTGCCGCCGCGGCCTGCGGGCACGCCTGGGCGCATCGAGATCGTGGA
GGCCGCGCACCCGGTGCCGGACGCAGCGGGCGAGGCGGTGGCGCGGCGCATGCTGGAACTGGCGCAGGGGCTCACCGCCG
ACGACCTCGTGATCTGCCTGATCTCGGGCGGCGGCTCCGCACTGCTCACGCTGCCGGCCGAGGGCCTGGCGCTGGAGGAC
AAGCAGCGCATCCACCGGGCCCTGTTGGAAAGCGGTGCGGGCATTGCGGACATGAACTGCGTGCGCCGGCACCTCTCGCG
CATCAAAGGCGGGCGGCTGGCCTCGGCCTGCGCGCCCGCGCGCGTCGTGACGCTCGCGATCAGCGACGTGCCGGGCGACG
ATCCGGCAGTGATCGCAAGCGGCCCCACGGTGCCGGACGCGACGACCTGCGCCGATGCGCTGCGCATCCTGGACCGCCAT
GGCATCGGCCTGCCACCGGCCGTGCGCGCGGCGCTGGAGGCCGGTACGCTGGAAACGCCCAAGCCTTTGCCGGGCGAGAC
GCCGGAGGTGCACCTGATCGCCACGCCGCTCCAGTCGCTGGAAGCCGCGGCCGCGGCGGCCCGCTCCGCGGGCCTGGCGG
TGCATGTCCTGTCGGACGAGATGGAAGGCGAATCCCGTGAGGTGGGTGCCGTGCATGCCGCGCTGGCCCGCTCGGTGGCG
CGCCACGGTACGCCGTTCGCGCGGCCCTGCGTCATCCTCTCGGGCGGCGAGACCACGGTGACGGTGCGCGAGCGCCCGCC
GGGCAGCGCGCGCGGACGGGGCGGGCGCGCCGGGGAGTTCTGCCTGGGGCTGGCGCGCGCGCTGCAGGGCCAGGAGGGCG
TGTGGGCGCTGGCGGCCGATACCGACGGCATCGACGGCGTGGAGGACAACGCCGGTGCGCAGGTAGCGCCCGACACGCTC
GCCCGCGCAGCCGCGGCGGGCCTGCGCGTGGACGATCATTTGGCGCGCAACGACGCCTACGGCTTTTTTGCAGCGCTCGG
CGATCTGGTCGTCACCGGGCCGACGCATACGAACGTGAACGACTTCCGCGCCCTGCTCATACGCTAG

Upstream 100 bases:

>100_bases
GATTTTGTATGCAGTTTTTGTGCACCATAAGCGGGATCGGCATCGGGGCATACCCGCACCGGGGCGGTGCGCCGGGGCCG
CCTTGCGCCAGAATCCGCGC

Downstream 100 bases:

>100_bases
AACAGGGCTCGCCAGGGATCAGTACCCGAGCGTGCGCCCATCCGGATTGCGCGGATCGGAATAACCGAAAAGCACGCCGT
CCTTGAGCTGGATGGTCTGC

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MTLPALPPASAPSPAPDPAADPTRFLRHLYGVAVQAALPSVRLAAHLPAPPRGRTLVLGAGKAGASMVHALEALWPAEAP
LSGLVVTRYGHVPPRPAGTPGRIEIVEAAHPVPDAAGEAVARRMLELAQGLTADDLVICLISGGGSALLTLPAEGLALED
KQRIHRALLESGAGIADMNCVRRHLSRIKGGRLASACAPARVVTLAISDVPGDDPAVIASGPTVPDATTCADALRILDRH
GIGLPPAVRAALEAGTLETPKPLPGETPEVHLIATPLQSLEAAAAAARSAGLAVHVLSDEMEGESREVGAVHAALARSVA
RHGTPFARPCVILSGGETTVTVRERPPGSARGRGGRAGEFCLGLARALQGQEGVWALAADTDGIDGVEDNAGAQVAPDTL
ARAAAAGLRVDDHLARNDAYGFFAALGDLVVTGPTHTNVNDFRALLIR

Sequences:

>Translated_448_residues
MTLPALPPASAPSPAPDPAADPTRFLRHLYGVAVQAALPSVRLAAHLPAPPRGRTLVLGAGKAGASMVHALEALWPAEAP
LSGLVVTRYGHVPPRPAGTPGRIEIVEAAHPVPDAAGEAVARRMLELAQGLTADDLVICLISGGGSALLTLPAEGLALED
KQRIHRALLESGAGIADMNCVRRHLSRIKGGRLASACAPARVVTLAISDVPGDDPAVIASGPTVPDATTCADALRILDRH
GIGLPPAVRAALEAGTLETPKPLPGETPEVHLIATPLQSLEAAAAAARSAGLAVHVLSDEMEGESREVGAVHAALARSVA
RHGTPFARPCVILSGGETTVTVRERPPGSARGRGGRAGEFCLGLARALQGQEGVWALAADTDGIDGVEDNAGAQVAPDTL
ARAAAAGLRVDDHLARNDAYGFFAALGDLVVTGPTHTNVNDFRALLIR
>Mature_447_residues
TLPALPPASAPSPAPDPAADPTRFLRHLYGVAVQAALPSVRLAAHLPAPPRGRTLVLGAGKAGASMVHALEALWPAEAPL
SGLVVTRYGHVPPRPAGTPGRIEIVEAAHPVPDAAGEAVARRMLELAQGLTADDLVICLISGGGSALLTLPAEGLALEDK
QRIHRALLESGAGIADMNCVRRHLSRIKGGRLASACAPARVVTLAISDVPGDDPAVIASGPTVPDATTCADALRILDRHG
IGLPPAVRAALEAGTLETPKPLPGETPEVHLIATPLQSLEAAAAAARSAGLAVHVLSDEMEGESREVGAVHAALARSVAR
HGTPFARPCVILSGGETTVTVRERPPGSARGRGGRAGEFCLGLARALQGQEGVWALAADTDGIDGVEDNAGAQVAPDTLA
RAAAAGLRVDDHLARNDAYGFFAALGDLVVTGPTHTNVNDFRALLIR

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=490, Percent_Identity=34.0816326530612, Blast_Score=176, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI193205461, Length=383, Percent_Identity=30.8093994778068, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI19920578, Length=392, Percent_Identity=33.1632653061224, Blast_Score=135, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 45737; Mature: 45605

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPALPPASAPSPAPDPAADPTRFLRHLYGVAVQAALPSVRLAAHLPAPPRGRTLVLGA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEC
GKAGASMVHALEALWPAEAPLSGLVVTRYGHVPPRPAGTPGRIEIVEAAHPVPDAAGEAV
CCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHH
ARRMLELAQGLTADDLVICLISGGGSALLTLPAEGLALEDKQRIHRALLESGAGIADMNC
HHHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHH
VRRHLSRIKGGRLASACAPARVVTLAISDVPGDDPAVIASGPTVPDATTCADALRILDRH
HHHHHHHCCCCCHHHHCCCCEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHC
GIGLPPAVRAALEAGTLETPKPLPGETPEVHLIATPLQSLEAAAAAARSAGLAVHVLSDE
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCEEEEEECCC
MEGESREVGAVHAALARSVARHGTPFARPCVILSGGETTVTVRERPPGSARGRGGRAGEF
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCHHHH
CLGLARALQGQEGVWALAADTDGIDGVEDNAGAQVAPDTLARAAAAGLRVDDHLARNDAY
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEECHHHHHHHHHHCCCCHHHHHHCCCH
GFFAALGDLVVTGPTHTNVNDFRALLIR
HHHHHHCCEEEECCCCCCHHHHHHHCCC
>Mature Secondary Structure 
TLPALPPASAPSPAPDPAADPTRFLRHLYGVAVQAALPSVRLAAHLPAPPRGRTLVLGA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEC
GKAGASMVHALEALWPAEAPLSGLVVTRYGHVPPRPAGTPGRIEIVEAAHPVPDAAGEAV
CCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHH
ARRMLELAQGLTADDLVICLISGGGSALLTLPAEGLALEDKQRIHRALLESGAGIADMNC
HHHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHH
VRRHLSRIKGGRLASACAPARVVTLAISDVPGDDPAVIASGPTVPDATTCADALRILDRH
HHHHHHHCCCCCHHHHCCCCEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHC
GIGLPPAVRAALEAGTLETPKPLPGETPEVHLIATPLQSLEAAAAAARSAGLAVHVLSDE
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCEEEEEECCC
MEGESREVGAVHAALARSVARHGTPFARPCVILSGGETTVTVRERPPGSARGRGGRAGEF
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCHHHH
CLGLARALQGQEGVWALAADTDGIDGVEDNAGAQVAPDTLARAAAAGLRVDDHLARNDAY
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEECHHHHHHHHHHCCCCHHHHHHCCCH
GFFAALGDLVVTGPTHTNVNDFRALLIR
HHHHHHCCEEEECCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]