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The map label for this gene is infA1

Identifier: 120609778

GI number: 120609778

Start: 1190231

End: 1190488

Strand: Reverse

Name: infA1

Synonym: Aave_1086

Alternate gene names: 120609778

Gene position: 1190488-1190231 (Counterclockwise)

Preceding gene: 120609781

Following gene: 120609776

Centisome position: 22.24

GC content: 67.05

Gene sequence:

>258_bases
GTGTCCAAAGAAGACCTGATCGAAATGCAAGGCAAAGTGGAGGAAGTCCTGCCCGACTCCCGCTTCCGCGTGACCCTGGA
CAACGGGCACCAGCTCATCGCCTATGCGGGCGGCAAGATGCGCAAGCACCGCATCCGCGTGCTCGCCGGCGACCGCGTGT
CGCTGGAACTGTCCCCCTATGACCTCAACAAGGGCCGGCTCACCTTCCGGCACATCGAAGGCCGCGGCCCGCGCGCTCCC
CAGCGGGGCGCGCGCTGA

Upstream 100 bases:

>100_bases
CGCCCTCGACCAGGGCCGGCACATCGCCCTGCACGGCGCGGGCTGACGCACGGCCCCGCGCCCGTACATCCCTTTCTTTC
CCACCATCCGAAGGAGTTCC

Downstream 100 bases:

>100_bases
CCGCCCCCGCTGCCGTCAGTAGCGGTTGGAGAAGTTCGCGCTGATGCGCTGCTTCAGGTACTCGCCCGCCGTGATCGGCG
GGTGCGTGCCCGCCGGGCCC

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MSKEDLIEMQGKVEEVLPDSRFRVTLDNGHQLIAYAGGKMRKHRIRVLAGDRVSLELSPYDLNKGRLTFRHIEGRGPRAP
QRGAR

Sequences:

>Translated_85_residues
MSKEDLIEMQGKVEEVLPDSRFRVTLDNGHQLIAYAGGKMRKHRIRVLAGDRVSLELSPYDLNKGRLTFRHIEGRGPRAP
QRGAR
>Mature_84_residues
SKEDLIEMQGKVEEVLPDSRFRVTLDNGHQLIAYAGGKMRKHRIRVLAGDRVSLELSPYDLNKGRLTFRHIEGRGPRAPQ
RGAR

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=70, Percent_Identity=61.4285714285714, Blast_Score=97, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF11_ACIAC (A1TL44)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_969456.1
- ProteinModelPortal:   A1TL44
- SMR:   A1TL44
- STRING:   A1TL44
- GeneID:   4665836
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_1086
- NMPDR:   fig|397945.5.peg.942
- eggNOG:   COG0361
- HOGENOM:   HBG286099
- OMA:   KNNPKRN
- ProtClustDB:   PRK12442
- BioCyc:   AAVE397945:AAVE_1086-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 9696; Mature: 9565

Theoretical pI: Translated: 10.95; Mature: 10.95

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEDLIEMQGKVEEVLPDSRFRVTLDNGHQLIAYAGGKMRKHRIRVLAGDRVSLELSPY
CCCCHHHHHCCCHHHCCCCCEEEEEECCCCEEEEEECCCCCEEEEEEEECCEEEEEECCC
DLNKGRLTFRHIEGRGPRAPQRGAR
CCCCCEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SKEDLIEMQGKVEEVLPDSRFRVTLDNGHQLIAYAGGKMRKHRIRVLAGDRVSLELSPY
CCCHHHHHCCCHHHCCCCCEEEEEECCCCEEEEEECCCCCEEEEEEEECCEEEEEECCC
DLNKGRLTFRHIEGRGPRAPQRGAR
CCCCCEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA