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The map label for this gene is fabG [H]

Identifier: 120609772

GI number: 120609772

Start: 1183246

End: 1184076

Strand: Direct

Name: fabG [H]

Synonym: Aave_1080

Alternate gene names: 120609772

Gene position: 1183246-1184076 (Clockwise)

Preceding gene: 120609771

Following gene: 120609777

Centisome position: 22.11

GC content: 72.56

Gene sequence:

>831_bases
ATGGATCTGGGTATCACGGGCAAATGGGCACTGGTCTGCGGAGCGAGCAAGGGCCTGGGCTATGGCTGCGCCGAGGCGCT
GGTGCGCGAGGGCGTGAACGTGGTCATCAATGCGCGCAATCCCGAGGACCTGCGCCTGGCGGCCGCGCGGCTGGCTTCGG
CGGGCGCGGAGATCACGGCGGCCGCCGGCCAGAAGGGGCCACCGCCGCAGGTGGTGGCCGTGGCCGCCGACATCACCACG
CCGGAGGGGCGCGAGGCAGCGTTCGCCGCGCCGGGCGGGCCGGGGCGCGATTTCGACATCGTGGTGACGAACGCGGGCGG
CCCGCCGCCCGGCGATTTCCGCGAGTGGGACCGCGAGGCCTGGATCCGCGCGGTGGATGCCAACATGCTCACGCCGATCG
AGCTGATCAAGGCGACGGTGGACGGCATGGCGGCGCGCGGCTTCGGCCGCATCGTGAACATCACGTCGAGCGCGGTGAAG
GCGCCGATCGACATCCTGGGCCTGTCCAACGGCGCGCGCAGCGGCCTCACGGGGTTCGTGGCGGGCGCCGCGCGCAGCGG
CATCGCCGCCAAGGGCGTGACCATCAACAACCTGCTGCCCGGCAAGTTCGACACCGACCGGCTGGCGGCCACCATCCAGG
CGGCCGTGAAGAAGTCGGGCAAGAGCGAGGACGATGTGCGCCGGGCCCAGCAGGCGGCCATTCCGGCGGGCCGCTACGGC
ACGCCGCAGGAGTTCGGCGCGATCTGCGCCTTCCTCTGCAGCGTGCAGGCGGCCTACCTGACCGGGCAGAACGTGCTGGC
CGACGGCGGCGCCTATCCCGGGGCGTTCTGA

Upstream 100 bases:

>100_bases
CGGGCTTCCGTACCATCGCGGTTCCGGCGCCGGGCGCGCCACCACCAACCACTGCGTTGCCGCATTGCGCGGCACGGCGC
GGAAAGAAAGGACACGCACT

Downstream 100 bases:

>100_bases
GCGGCCGCTTGCCTGCTTTCCGGCCTGCCGTGCCGCGCGCGCCGTCAGGCGCCGAGCTTGAAGAAGCCGACCGTGGCGTT
GAGGTCCTTGCCCTGGTGAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MDLGITGKWALVCGASKGLGYGCAEALVREGVNVVINARNPEDLRLAAARLASAGAEITAAAGQKGPPPQVVAVAADITT
PEGREAAFAAPGGPGRDFDIVVTNAGGPPPGDFREWDREAWIRAVDANMLTPIELIKATVDGMAARGFGRIVNITSSAVK
APIDILGLSNGARSGLTGFVAGAARSGIAAKGVTINNLLPGKFDTDRLAATIQAAVKKSGKSEDDVRRAQQAAIPAGRYG
TPQEFGAICAFLCSVQAAYLTGQNVLADGGAYPGAF

Sequences:

>Translated_276_residues
MDLGITGKWALVCGASKGLGYGCAEALVREGVNVVINARNPEDLRLAAARLASAGAEITAAAGQKGPPPQVVAVAADITT
PEGREAAFAAPGGPGRDFDIVVTNAGGPPPGDFREWDREAWIRAVDANMLTPIELIKATVDGMAARGFGRIVNITSSAVK
APIDILGLSNGARSGLTGFVAGAARSGIAAKGVTINNLLPGKFDTDRLAATIQAAVKKSGKSEDDVRRAQQAAIPAGRYG
TPQEFGAICAFLCSVQAAYLTGQNVLADGGAYPGAF
>Mature_276_residues
MDLGITGKWALVCGASKGLGYGCAEALVREGVNVVINARNPEDLRLAAARLASAGAEITAAAGQKGPPPQVVAVAADITT
PEGREAAFAAPGGPGRDFDIVVTNAGGPPPGDFREWDREAWIRAVDANMLTPIELIKATVDGMAARGFGRIVNITSSAVK
APIDILGLSNGARSGLTGFVAGAARSGIAAKGVTINNLLPGKFDTDRLAATIQAAVKKSGKSEDDVRRAQQAAIPAGRYG
TPQEFGAICAFLCSVQAAYLTGQNVLADGGAYPGAF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=267, Percent_Identity=26.2172284644195, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI5031737, Length=262, Percent_Identity=24.0458015267176, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI19923817, Length=270, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI66933014, Length=177, Percent_Identity=28.8135593220339, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787335, Length=272, Percent_Identity=30.5147058823529, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082100, Length=274, Percent_Identity=31.3868613138686, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790717, Length=273, Percent_Identity=26.007326007326, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788459, Length=264, Percent_Identity=25.3787878787879, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082160, Length=277, Percent_Identity=24.9097472924188, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787905, Length=272, Percent_Identity=26.8382352941176, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1789208, Length=271, Percent_Identity=25.4612546125461, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=272, Percent_Identity=28.3088235294118, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=268, Percent_Identity=26.865671641791, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=271, Percent_Identity=27.3062730627306, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=276, Percent_Identity=27.1739130434783, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=277, Percent_Identity=27.4368231046931, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=275, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=274, Percent_Identity=26.2773722627737, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=276, Percent_Identity=25.7246376811594, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=272, Percent_Identity=25, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=278, Percent_Identity=26.2589928057554, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=272, Percent_Identity=29.0441176470588, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=278, Percent_Identity=26.978417266187, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=275, Percent_Identity=25.8181818181818, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=274, Percent_Identity=26.6423357664234, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=26.4705882352941, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=275, Percent_Identity=24.7272727272727, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=268, Percent_Identity=23.8805970149254, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=271, Percent_Identity=25.4612546125461, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=267, Percent_Identity=26.9662921348315, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355319, Length=267, Percent_Identity=26.2172284644195, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639444, Length=275, Percent_Identity=26.9090909090909, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI23397609, Length=276, Percent_Identity=27.1739130434783, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28571526, Length=279, Percent_Identity=29.0322580645161, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28072; Mature: 28072

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGITGKWALVCGASKGLGYGCAEALVREGVNVVINARNPEDLRLAAARLASAGAEITA
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCEEEE
AAGQKGPPPQVVAVAADITTPEGREAAFAAPGGPGRDFDIVVTNAGGPPPGDFREWDREA
CCCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHH
WIRAVDANMLTPIELIKATVDGMAARGFGRIVNITSSAVKAPIDILGLSNGARSGLTGFV
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEECHHHHHCCEEEEECCCCCCCCCHHHH
AGAARSGIAAKGVTINNLLPGKFDTDRLAATIQAAVKKSGKSEDDVRRAQQAAIPAGRYG
HHHHHCCCEECCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
TPQEFGAICAFLCSVQAAYLTGQNVLADGGAYPGAF
CHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
>Mature Secondary Structure
MDLGITGKWALVCGASKGLGYGCAEALVREGVNVVINARNPEDLRLAAARLASAGAEITA
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCEEEE
AAGQKGPPPQVVAVAADITTPEGREAAFAAPGGPGRDFDIVVTNAGGPPPGDFREWDREA
CCCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHH
WIRAVDANMLTPIELIKATVDGMAARGFGRIVNITSSAVKAPIDILGLSNGARSGLTGFV
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEECHHHHHCCEEEEECCCCCCCCCHHHH
AGAARSGIAAKGVTINNLLPGKFDTDRLAATIQAAVKKSGKSEDDVRRAQQAAIPAGRYG
HHHHHCCCEECCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
TPQEFGAICAFLCSVQAAYLTGQNVLADGGAYPGAF
CHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]