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The map label for this gene is trxB [H]

Identifier: 120609770

GI number: 120609770

Start: 1180845

End: 1181849

Strand: Direct

Name: trxB [H]

Synonym: Aave_1078

Alternate gene names: 120609770

Gene position: 1180845-1181849 (Clockwise)

Preceding gene: 120609768

Following gene: 120609771

Centisome position: 22.06

GC content: 71.94

Gene sequence:

>1005_bases
ATGGCAGCAGACATGGCGGCAGGCGACGGAACAGGCCCCGAGGGCGGGACAAGCGACTTCGACAGCGATGTGCTCGTCAT
CGGCGGTGGCCCGGCCGGGCTGACGGCGGCGCTCTACCTCGCGCGCTTCCGGCGCTCGGTGGTGCTGGTGGATGCCGGCG
ACAGCCGCGTCGCGAAGATTCCGCGCTCGCACAACTATCCCGGTTTCGTGGATGGAATTCCGGGCCATTCGCTGCTGGAG
ACACTGCGCGCGCAGATGCGGCGCTATCCGATCCGCACCGTGCGCGCCGCGATCGAACGCATCGAGCGCGTGGCGCCGGC
CGAAGGCGCATCCGGCCCAGCGGAAGGGCAAGGACAAGGGCAAGGGTTCTTCCATGCGCACTGGCGCGGCGGAGGCAGCG
TGCGCGCGCCGTTCGTGCTGCTGGCCACGGGTGTGGAAGATATCCCGCCGCCGATGCCGCACGTGCGGCAGGCCCTGGAG
GACGGACTGCTGCGCTACTGCCCCGTGTGCGATGCCTACGAAGCGATCGGCCAGGGGATCGGCGTCATCGCCGAGGGGGC
GCACGGGGTCGGCGAGGCGATCTACCTGCGGCATTTCAGCGCCGACGTCACGCTGTTCCTCGCGCCCGGCGATACGGTGC
TGTCGGGTGATGACCGAGAGCGGCTGGTGCGCGCCGGCATCCGCTGGGTGCAGGCACCCGTGGACGCGATCCGCCGCGAG
GGGGACCGCGTGGTGGTGCACCATGCGGGGGGCAGTTCGGCGTGCGACACGCTCTACTGCGCGCTGGGCCTGCAGATCCA
TGCGGGCCTGGCCGCCGGGCTGGGCGCCGCGCTGGACGCATCGGGCTACGTGGTGGTGGATGCCCACGGCGCGACCACGG
TGCCGGGTCTCTATGCGGCGGGCGACGTGGCGCAGGGGCTGAACCAGATCGCCGTGGCGGCGGGCGGCGCGGCCATCGCG
TCCTCGGCCATTCACGTGGCGCTGGGGCCGTCGTCCGGCACCTAG

Upstream 100 bases:

>100_bases
CCCGGGTACGGCAATTGCCGAAGTCTCCGGAATGGGCGCGGATGGTGCGCCCGTCCAGTTCCGCGGGTTGCGGATGCGGT
GCGGAATCCACGGAGCGAAG

Downstream 100 bases:

>100_bases
CGAGGCCGCGGCCGGCATCGCGGTTCACGGTGCCCGCATTCCGCACTGCAGGGGGCCTGCCGGCGCCGTGCGTGCGACAC
TGGCCGGCTCCCCCACGATC

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: TR; TRXR [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAADMAAGDGTGPEGGTSDFDSDVLVIGGGPAGLTAALYLARFRRSVVLVDAGDSRVAKIPRSHNYPGFVDGIPGHSLLE
TLRAQMRRYPIRTVRAAIERIERVAPAEGASGPAEGQGQGQGFFHAHWRGGGSVRAPFVLLATGVEDIPPPMPHVRQALE
DGLLRYCPVCDAYEAIGQGIGVIAEGAHGVGEAIYLRHFSADVTLFLAPGDTVLSGDDRERLVRAGIRWVQAPVDAIRRE
GDRVVVHHAGGSSACDTLYCALGLQIHAGLAAGLGAALDASGYVVVDAHGATTVPGLYAAGDVAQGLNQIAVAAGGAAIA
SSAIHVALGPSSGT

Sequences:

>Translated_334_residues
MAADMAAGDGTGPEGGTSDFDSDVLVIGGGPAGLTAALYLARFRRSVVLVDAGDSRVAKIPRSHNYPGFVDGIPGHSLLE
TLRAQMRRYPIRTVRAAIERIERVAPAEGASGPAEGQGQGQGFFHAHWRGGGSVRAPFVLLATGVEDIPPPMPHVRQALE
DGLLRYCPVCDAYEAIGQGIGVIAEGAHGVGEAIYLRHFSADVTLFLAPGDTVLSGDDRERLVRAGIRWVQAPVDAIRRE
GDRVVVHHAGGSSACDTLYCALGLQIHAGLAAGLGAALDASGYVVVDAHGATTVPGLYAAGDVAQGLNQIAVAAGGAAIA
SSAIHVALGPSSGT
>Mature_333_residues
AADMAAGDGTGPEGGTSDFDSDVLVIGGGPAGLTAALYLARFRRSVVLVDAGDSRVAKIPRSHNYPGFVDGIPGHSLLET
LRAQMRRYPIRTVRAAIERIERVAPAEGASGPAEGQGQGQGFFHAHWRGGGSVRAPFVLLATGVEDIPPPMPHVRQALED
GLLRYCPVCDAYEAIGQGIGVIAEGAHGVGEAIYLRHFSADVTLFLAPGDTVLSGDDRERLVRAGIRWVQAPVDAIRREG
DRVVVHHAGGSSACDTLYCALGLQIHAGLAAGLGAALDASGYVVVDAHGATTVPGLYAAGDVAQGLNQIAVAAGGAAIAS
SAIHVALGPSSGT

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34158; Mature: 34027

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADMAAGDGTGPEGGTSDFDSDVLVIGGGPAGLTAALYLARFRRSVVLVDAGDSRVAKI
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCHHEEC
PRSHNYPGFVDGIPGHSLLETLRAQMRRYPIRTVRAAIERIERVAPAEGASGPAEGQGQG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
QGFFHAHWRGGGSVRAPFVLLATGVEDIPPPMPHVRQALEDGLLRYCPVCDAYEAIGQGI
CCEEEEEECCCCCCCCCEEEEECCCHHCCCCCHHHHHHHHHCHHHHCCCHHHHHHHHCCC
GVIAEGAHGVGEAIYLRHFSADVTLFLAPGDTVLSGDDRERLVRAGIRWVQAPVDAIRRE
CEEECCCCCCCCEEEEEEECCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCC
GDRVVVHHAGGSSACDTLYCALGLQIHAGLAAGLGAALDASGYVVVDAHGATTVPGLYAA
CCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHCCHHCCCCCEEEEECCCCCCCCCHHHH
GDVAQGLNQIAVAAGGAAIASSAIHVALGPSSGT
HHHHHHHHHHHHHCCCHHHHCCEEEEEECCCCCC
>Mature Secondary Structure 
AADMAAGDGTGPEGGTSDFDSDVLVIGGGPAGLTAALYLARFRRSVVLVDAGDSRVAKI
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCHHEEC
PRSHNYPGFVDGIPGHSLLETLRAQMRRYPIRTVRAAIERIERVAPAEGASGPAEGQGQG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
QGFFHAHWRGGGSVRAPFVLLATGVEDIPPPMPHVRQALEDGLLRYCPVCDAYEAIGQGI
CCEEEEEECCCCCCCCCEEEEECCCHHCCCCCHHHHHHHHHCHHHHCCCHHHHHHHHCCC
GVIAEGAHGVGEAIYLRHFSADVTLFLAPGDTVLSGDDRERLVRAGIRWVQAPVDAIRRE
CEEECCCCCCCCEEEEEEECCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCC
GDRVVVHHAGGSSACDTLYCALGLQIHAGLAAGLGAALDASGYVVVDAHGATTVPGLYAA
CCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHCCHHCCCCCEEEEECCCCCCCCCHHHH
GDVAQGLNQIAVAAGGAAIASSAIHVALGPSSGT
HHHHHHHHHHHHHCCCHHHHCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]