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The map label for this gene is mlaC [H]

Identifier: 120609711

GI number: 120609711

Start: 1118062

End: 1118718

Strand: Direct

Name: mlaC [H]

Synonym: Aave_1017

Alternate gene names: 120609711

Gene position: 1118062-1118718 (Clockwise)

Preceding gene: 120609710

Following gene: 120609712

Centisome position: 20.89

GC content: 67.43

Gene sequence:

>657_bases
ATGACGATGAGCCGACGTACCCTGGGCCATGCCGCCCTCTGCACTGCCGCCGTTCTGTGGCTGGGCATGCCGGTGGCGGC
CCTGGCCGCCGACGAAACGCCCGACGAACTGATCAAGCGCCTGTCCACCGACGTGCTGAACACCGTGCGCAGCGACAAGA
GCATCAAGTCGGGCGACATCAACAAGATCACCGCGCTGGTGGACAAGGTCATCCTGCCGCACGTGAACTTCCGCCGCATG
ACAGCCGCCGCGGTGGGCCCGGCCTGGCGCCAGGCCACGCCGCAGCAGCAGACGCGCCTGCAGGACGAATTCAAGTCGCT
GCTCGTGCGCACCTACTCGGGCGCCCTCAACCAGGTCAACGACCTGTCGATCCAGGTCAAGCCGCTGCGCGCCGGCGCCG
ACGACAAGGACGTGCTCGTGCGTTCCGAGATCCTGGGCCGCGGCGACCCTATCCAGCTCGACTACCGCCTGGAGAAGACC
CCGGGCGACGGCGCGGGCTGGAAGATCTACAACCTGAACGTGATGGGCGTGTGGCTGGTCGAGACCTACCGCACGCAGTT
CGCGCAGGAGATCAACGCCAAGGGCATCGATGGCCTCATCGAATCCCTGGCGGCGCGCAACAAGGCCAACGCCGCCGGCT
CCGGCAAGGCGGGCTGA

Upstream 100 bases:

>100_bases
CCGTGCACCGGGCAGACGCATGGGGGCGTCGCCCCGCGTCCACAATGGAACATGACATGGCGCGCCCCGCCGGGGACGCG
CCTTCAGAAAGGAAACCGAT

Downstream 100 bases:

>100_bases
CGCATCCATCGGGCGGCCGCCATGCTGGTCCTACCCACCGAGCTGACGCACCGACAGGCCGAGGCCTGCCTTCGCATGCT
GCTGCAGGGGCTCAAGGCGC

Product: toluene tolerance family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTMSRRTLGHAALCTAAVLWLGMPVAALAADETPDELIKRLSTDVLNTVRSDKSIKSGDINKITALVDKVILPHVNFRRM
TAAAVGPAWRQATPQQQTRLQDEFKSLLVRTYSGALNQVNDLSIQVKPLRAGADDKDVLVRSEILGRGDPIQLDYRLEKT
PGDGAGWKIYNLNVMGVWLVETYRTQFAQEINAKGIDGLIESLAARNKANAAGSGKAG

Sequences:

>Translated_218_residues
MTMSRRTLGHAALCTAAVLWLGMPVAALAADETPDELIKRLSTDVLNTVRSDKSIKSGDINKITALVDKVILPHVNFRRM
TAAAVGPAWRQATPQQQTRLQDEFKSLLVRTYSGALNQVNDLSIQVKPLRAGADDKDVLVRSEILGRGDPIQLDYRLEKT
PGDGAGWKIYNLNVMGVWLVETYRTQFAQEINAKGIDGLIESLAARNKANAAGSGKAG
>Mature_217_residues
TMSRRTLGHAALCTAAVLWLGMPVAALAADETPDELIKRLSTDVLNTVRSDKSIKSGDINKITALVDKVILPHVNFRRMT
AAAVGPAWRQATPQQQTRLQDEFKSLLVRTYSGALNQVNDLSIQVKPLRAGADDKDVLVRSEILGRGDPIQLDYRLEKTP
GDGAGWKIYNLNVMGVWLVETYRTQFAQEINAKGIDGLIESLAARNKANAAGSGKAG

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=195, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 23710; Mature: 23578

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMSRRTLGHAALCTAAVLWLGMPVAALAADETPDELIKRLSTDVLNTVRSDKSIKSGDI
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCH
NKITALVDKVILPHVNFRRMTAAAVGPAWRQATPQQQTRLQDEFKSLLVRTYSGALNQVN
HHHHHHHHHHHHCCCCHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
DLSIQVKPLRAGADDKDVLVRSEILGRGDPIQLDYRLEKTPGDGAGWKIYNLNVMGVWLV
CCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCEEEEEEEEEEHHHH
ETYRTQFAQEINAKGIDGLIESLAARNKANAAGSGKAG
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TMSRRTLGHAALCTAAVLWLGMPVAALAADETPDELIKRLSTDVLNTVRSDKSIKSGDI
CCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCH
NKITALVDKVILPHVNFRRMTAAAVGPAWRQATPQQQTRLQDEFKSLLVRTYSGALNQVN
HHHHHHHHHHHHCCCCHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
DLSIQVKPLRAGADDKDVLVRSEILGRGDPIQLDYRLEKTPGDGAGWKIYNLNVMGVWLV
CCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCEEEEEEEEEEHHHH
ETYRTQFAQEINAKGIDGLIESLAARNKANAAGSGKAG
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]