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The map label for this gene is mlaD [H]

Identifier: 120609709

GI number: 120609709

Start: 1116649

End: 1117140

Strand: Direct

Name: mlaD [H]

Synonym: Aave_1015

Alternate gene names: 120609709

Gene position: 1116649-1117140 (Clockwise)

Preceding gene: 120609708

Following gene: 120609710

Centisome position: 20.86

GC content: 66.26

Gene sequence:

>492_bases
ATGCAGCATTCCAAGAACGACGTCTGGGTCGGCCTCTTCGTCCTCCTCGGCGGTGCGGCCCTGCTCTTCCTCGCCCTGCA
GTCGGCCAACCTGCTGCGCGTGCAGTGGCAGTCCGGCTACCACGTCACCGCGCTCTTCGACAACATCGGCGGGCTCAAGC
CCCAGTCCGCGGTGCGCAGCGCCGGCGTGGTGGTCGGGCGGGTGAATTCCATCACCTTCGACGACAAGACCTTCCAGGCC
CAGGTGACGCTGGAGATGGACAAGCGCTACGCCTTCCCCAAGGACAGCTCGCTCAAGATCCTCACCAGCGGCCTGCTGGG
CGACCAGTACATCGGCATCCAGGCGGGTGCCGACGAAAAGAACCTCGCCGAGGGCGACCGCATCACGTCAACGCAGTCCG
CGGTGGTGCTGGAAAACCTCATCGGCCAGTTCCTCTACGGCAAGGCCGAAGAGGGCGGCGGCGGGGCCTCCGCGGGCGGC
TCCAAGAAATGA

Upstream 100 bases:

>100_bases
TGGCCTCGCTCACGGTGCTGGGGCTGGATTTCCTGCTCACGGCCTGGATGTTCAGCATCTGACGCGGCAGCGCCCAAGAA
CCCTTCAGAGAGAAAACACC

Downstream 100 bases:

>100_bases
CGACAACAATGATGACCACCAATTGCCAAGCTCTCCGGGCCCCGTCCCTGCGCGGCAGCGCCTGCGCGCTGGCCGTGGCC
AGCCTGCTGGCCGGCTGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MQHSKNDVWVGLFVLLGGAALLFLALQSANLLRVQWQSGYHVTALFDNIGGLKPQSAVRSAGVVVGRVNSITFDDKTFQA
QVTLEMDKRYAFPKDSSLKILTSGLLGDQYIGIQAGADEKNLAEGDRITSTQSAVVLENLIGQFLYGKAEEGGGGASAGG
SKK

Sequences:

>Translated_163_residues
MQHSKNDVWVGLFVLLGGAALLFLALQSANLLRVQWQSGYHVTALFDNIGGLKPQSAVRSAGVVVGRVNSITFDDKTFQA
QVTLEMDKRYAFPKDSSLKILTSGLLGDQYIGIQAGADEKNLAEGDRITSTQSAVVLENLIGQFLYGKAEEGGGGASAGG
SKK
>Mature_163_residues
MQHSKNDVWVGLFVLLGGAALLFLALQSANLLRVQWQSGYHVTALFDNIGGLKPQSAVRSAGVVVGRVNSITFDDKTFQA
QVTLEMDKRYAFPKDSSLKILTSGLLGDQYIGIQAGADEKNLAEGDRITSTQSAVVLENLIGQFLYGKAEEGGGGASAGG
SKK

Specific function: Part of the ABC transporter complex mlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner memb

COG id: COG1463

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaD family [H]

Homologues:

Organism=Escherichia coli, GI1789584, Length=153, Percent_Identity=50.3267973856209, Blast_Score=143, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003399 [H]

Pfam domain/function: PF02470 MCE [H]

EC number: NA

Molecular weight: Translated: 17291; Mature: 17291

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHSKNDVWVGLFVLLGGAALLFLALQSANLLRVQWQSGYHVTALFDNIGGLKPQSAVRS
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCHHHHHH
AGVVVGRVNSITFDDKTFQAQVTLEMDKRYAFPKDSSLKILTSGLLGDQYIGIQAGADEK
CCEEEEECCEEEECCCEEEEEEEEEECCEECCCCCCCCEEEECCCCCCEEEEEECCCCCC
NLAEGDRITSTQSAVVLENLIGQFLYGKAEEGGGGASAGGSKK
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQHSKNDVWVGLFVLLGGAALLFLALQSANLLRVQWQSGYHVTALFDNIGGLKPQSAVRS
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCHHHHHH
AGVVVGRVNSITFDDKTFQAQVTLEMDKRYAFPKDSSLKILTSGLLGDQYIGIQAGADEK
CCEEEEECCEEEECCCEEEEEEEEEECCEECCCCCCCCEEEECCCCCCEEEEEECCCCCC
NLAEGDRITSTQSAVVLENLIGQFLYGKAEEGGGGASAGGSKK
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]