Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 120609697

GI number: 120609697

Start: 1100695

End: 1101825

Strand: Direct

Name: aroB [H]

Synonym: Aave_1003

Alternate gene names: 120609697

Gene position: 1100695-1101825 (Clockwise)

Preceding gene: 120609696

Following gene: 120609698

Centisome position: 20.56

GC content: 71.35

Gene sequence:

>1131_bases
ATGGCCCCGCCCGTGGCGTCGCCTGCGCCGCAGGCGCATGCCGGCCGCGTGGAGATCGCGCTGGGCGACCGGAGTTACGG
TATCGAGATCGGCGCGGGTCTGCTGGGCGATGCCCGGACCTACGGCGCGCTGCCCAGGGCCGCCCGCGCGTTGATCGTGA
CGAACGAGACGGTGGCGCCGCTCTACGCGGAGCCGTTGCGCGCCGCGCTGTCCGCGCACTATGCCGATGTCGTCCTGGCC
GTGCTGCCCGACGGCGAGGAGCACAAGGACTGGCCGACGCTGAACCGCATCTTCGATGCGCTGCTGTCGCACGGCTGTGA
CCGCAAGACGGTGCTTTTCGCGCTGGGCGGAGGTGTCGTGGGCGACATGACCGGCTTCGCCGCCGCGAGCTACATGCGTG
GCGTGCCGTTCGTGCAGGTGCCCACGACACTGCTCGCGCAGGTCGATTCTTCGGTGGGCGGCAAGACGGCCATCAACCAC
CCCCTGGGCAAGAACATGATCGGGGCGTTCTACCAGCCGCAGCTGGTGGTGTGCGACCTCGCCACCCTGGCGACGCTGCC
CGCGCGGGAGTTGAGCGCGGGCCTGGCCGAGGTCATCAAGTACGGCCCGATCGCGGACATGGAATTCCTGGCCTGGCTCG
AAGACCATGTCGAAGCCCTGCGCGCGGGCGACCACGCGGCCCTGGCCCACGCCGTGCGCCGCAGTTGCGAAATCAAGGCC
TGGGTGGTGGGGCAGGACGAGCGGGAGGCCGGCCTGCGCGCCATCCTGAACTTCGGCCATACCTTCGGGCACGCGATCGA
GGCGGGCATGGGCTATGGCGTGTGGCTGCACGGCGAAGGCGTGGGGGCGGGCATGGTGATGGCCGCCGAGCTGTCGCGCC
GGCTGGGCCTGGTGGACGAGGCGTTCACCGCGCGGTTGCGCCGCCTCGTCGAGCGAGCCGGCCTTCCCGTGCGGGGCGCC
GTGCTCGATCCTGCCGACAACGCCGGCCGCTACCTGGAGCTCATGCGCCTGGACAAGAAGTCGGAAGGGGGCGAGATCCG
TTTCGTCGTCATCGACGGACCGGGCCGCGCCGCCGTGCGTCCCGCGCCCGACGCGCTGGTGCGCGAGGTCATCGGCGCCT
GCTGCGCGTGA

Upstream 100 bases:

>100_bases
AGCCGATAGACTCCACGGCATGACTGCCGACGCATTTTCCGTTCGAGACACCGACCGGTCCCTTCCGTCCTCCCATACCG
GCGCCGCCGTGGCGGACCGC

Downstream 100 bases:

>100_bases
GCTGAGGATGCGGGAGCGCCCGATGGCGGACATGCATTCCCCCGGCGCAGTCGGGCAGTCCGGTGCCGGCGCGGTGGAAG
GCGCCGCGGGCCAGACTGCC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MAPPVASPAPQAHAGRVEIALGDRSYGIEIGAGLLGDARTYGALPRAARALIVTNETVAPLYAEPLRAALSAHYADVVLA
VLPDGEEHKDWPTLNRIFDALLSHGCDRKTVLFALGGGVVGDMTGFAAASYMRGVPFVQVPTTLLAQVDSSVGGKTAINH
PLGKNMIGAFYQPQLVVCDLATLATLPARELSAGLAEVIKYGPIADMEFLAWLEDHVEALRAGDHAALAHAVRRSCEIKA
WVVGQDEREAGLRAILNFGHTFGHAIEAGMGYGVWLHGEGVGAGMVMAAELSRRLGLVDEAFTARLRRLVERAGLPVRGA
VLDPADNAGRYLELMRLDKKSEGGEIRFVVIDGPGRAAVRPAPDALVREVIGACCA

Sequences:

>Translated_376_residues
MAPPVASPAPQAHAGRVEIALGDRSYGIEIGAGLLGDARTYGALPRAARALIVTNETVAPLYAEPLRAALSAHYADVVLA
VLPDGEEHKDWPTLNRIFDALLSHGCDRKTVLFALGGGVVGDMTGFAAASYMRGVPFVQVPTTLLAQVDSSVGGKTAINH
PLGKNMIGAFYQPQLVVCDLATLATLPARELSAGLAEVIKYGPIADMEFLAWLEDHVEALRAGDHAALAHAVRRSCEIKA
WVVGQDEREAGLRAILNFGHTFGHAIEAGMGYGVWLHGEGVGAGMVMAAELSRRLGLVDEAFTARLRRLVERAGLPVRGA
VLDPADNAGRYLELMRLDKKSEGGEIRFVVIDGPGRAAVRPAPDALVREVIGACCA
>Mature_375_residues
APPVASPAPQAHAGRVEIALGDRSYGIEIGAGLLGDARTYGALPRAARALIVTNETVAPLYAEPLRAALSAHYADVVLAV
LPDGEEHKDWPTLNRIFDALLSHGCDRKTVLFALGGGVVGDMTGFAAASYMRGVPFVQVPTTLLAQVDSSVGGKTAINHP
LGKNMIGAFYQPQLVVCDLATLATLPARELSAGLAEVIKYGPIADMEFLAWLEDHVEALRAGDHAALAHAVRRSCEIKAW
VVGQDEREAGLRAILNFGHTFGHAIEAGMGYGVWLHGEGVGAGMVMAAELSRRLGLVDEAFTARLRRLVERAGLPVRGAV
LDPADNAGRYLELMRLDKKSEGGEIRFVVIDGPGRAAVRPAPDALVREVIGACCA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=361, Percent_Identity=55.4016620498615, Blast_Score=354, Evalue=4e-99,
Organism=Saccharomyces cerevisiae, GI6320332, Length=340, Percent_Identity=40.2941176470588, Blast_Score=214, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39728; Mature: 39597

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPPVASPAPQAHAGRVEIALGDRSYGIEIGAGLLGDARTYGALPRAARALIVTNETVAP
CCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCCCCCHHHCCCCHHCEEEEEECCCCCH
LYAEPLRAALSAHYADVVLAVLPDGEEHKDWPTLNRIFDALLSHGCDRKTVLFALGGGVV
HHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHH
GDMTGFAAASYMRGVPFVQVPTTLLAQVDSSVGGKTAINHPLGKNMIGAFYQPQLVVCDL
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEEEH
ATLATLPARELSAGLAEVIKYGPIADMEFLAWLEDHVEALRAGDHAALAHAVRRSCEIKA
HHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEE
WVVGQDEREAGLRAILNFGHTFGHAIEAGMGYGVWLHGEGVGAGMVMAAELSRRLGLVDE
EEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCHHH
AFTARLRRLVERAGLPVRGAVLDPADNAGRYLELMRLDKKSEGGEIRFVVIDGPGRAAVR
HHHHHHHHHHHHCCCCEECEEECCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCC
PAPDALVREVIGACCA
CCHHHHHHHHHHHHCC
>Mature Secondary Structure 
APPVASPAPQAHAGRVEIALGDRSYGIEIGAGLLGDARTYGALPRAARALIVTNETVAP
CCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCCCCCHHHCCCCHHCEEEEEECCCCCH
LYAEPLRAALSAHYADVVLAVLPDGEEHKDWPTLNRIFDALLSHGCDRKTVLFALGGGVV
HHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHH
GDMTGFAAASYMRGVPFVQVPTTLLAQVDSSVGGKTAINHPLGKNMIGAFYQPQLVVCDL
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEEEH
ATLATLPARELSAGLAEVIKYGPIADMEFLAWLEDHVEALRAGDHAALAHAVRRSCEIKA
HHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEE
WVVGQDEREAGLRAILNFGHTFGHAIEAGMGYGVWLHGEGVGAGMVMAAELSRRLGLVDE
EEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCHHH
AFTARLRRLVERAGLPVRGAVLDPADNAGRYLELMRLDKKSEGGEIRFVVIDGPGRAAVR
HHHHHHHHHHHHCCCCEECEEECCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCC
PAPDALVREVIGACCA
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA