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The map label for this gene is pilQ [H]

Identifier: 120609694

GI number: 120609694

Start: 1096037

End: 1098184

Strand: Direct

Name: pilQ [H]

Synonym: Aave_1000

Alternate gene names: 120609694

Gene position: 1096037-1098184 (Clockwise)

Preceding gene: 120609693

Following gene: 120609695

Centisome position: 20.48

GC content: 65.6

Gene sequence:

>2148_bases
ATGATTCGAACGAAATGGTTTGGTTTTCGCTGCCGGGCGGCCTTGCTGGCTGCCGCAGCCACGTTGTGCAGTACCTGGGC
CCATGCGCAGGCCGCGATCGAGTCGGTCACGGGTGCAGTGCAGGGCGGAACGGAAATGGTCCGCATCGAGCTGTCGCAGC
CGCTCGGCGCCGTGCCTTCGGGCTTCGCGATCCAGGCACCCGCCCGCATCGCGCTGGACTTCCCCAACACCACCAACGGG
ACGGGCAAGTCGCTGGTCGAGGTGAACCAGGGCAACCTGAAGTCGGTGAACATCGTCCAGGCAGGCGACCGTTCACGGGT
GGTCCTCAATCTCAAGCAACCCACGTCCTACAAGGCGGAAGTGCAGGGTTCCGCCCTCATGGTGTCGCTGGAGCCCGTGT
CCGGCGGGGCTGTGTCCAATGCGGCCGCCCCCGCGGTGTTCGCTGAAAACCGCAATACCGACGTGCTTCCGCTGCGCGAC
GTGGATTTCCGCCGCGGCACCGACGGCGCCGGCCGGGTCATCGTTGGCCTGGCCAACAACCAGGTGGGCGTGGACCTGCG
CAAGCAGGGCAACAACCTCGTGGTGGAATTCCTCAAGTCCTCGCTGCCCGAGGGGCTGCGCAGGCGCCTCGACGTCACGG
ACTTCGGCACGCCCGTGCGCACCGTGACCACCACCACCCAGGGCGAGCGCGTGCGCATGACGATCGAGCCCATCGGGGAG
TGGGAGCACAGCGCCTACCAGAGCGACAACCAGTTCGTGGTCGAGGTGCGGCAGAAGAAGGTCGATCTGAACAAGCTGAG
CCAGGGACCGGGCTTCAGCGGCGAGAAGCTGTCGCTCAACTTCCAGAACATCGAGGTGCGCTCGCTGCTGCAGGTGATCG
CGGACTTCACCAATTTCAACATCGTCACGTCCGACACGGTGACCGGCGCCCTCACGCTCCGGCTCAAGGATGTGCCCTGG
GACCAGGCGCTGCAGATCATCATGGATGCCAAGGGCCTGGGCATGCGCAAGTCCGGCACCGTGCTGTGGATCGCCCCGAA
GGACGAGATCGACGCCCGTACGAAGAAGGACTATGAAGCGGCGCTCGCCATCCAGAAGCTCGAACCGCTGCGCACGCAGG
CCTTCCAGCTCAACTACGCCAAGGCGGCCGACATGGTGACCCAGCTGGCCAACAACAGCACCGGCAGCACCGGCACGTCC
ACCCGCTTCCTGTCCGAGCGTGGCAGCGCGATCGCCGAGCCTCGCACCAACCAGCTCTTCGTCACCGACACTCCTTCCAA
GCTGGAAGAGGTGCGCCAGCTGCTCAGCACGCTGGACGTGGCCGTGCGCCAGGTGATGATCGAGGCGCGCATCGTCGAGG
CGCGCGACACCTTCGGCCGCTCCCTGGGCGTGCGCCTGGGTGGCGCCGACCTGCGGGCCAACCGCGGGGGAGACGGCGGC
TACAGCGTGGGCGGCAACAACCGCCTCGCGATCGGCACCAGCTACAACAACGCCGTCGCATCGAGCGGCGCGGGCGGAAC
GGTGGCGACGGGGTCGGATGCCGCCGGCTCCACCTTCGTGAACCTGCCGGCCGCGCTCTCTTCCGGCGCCAGCTTCGGCA
ACTTCGCGCTGACGCTCTTCAATTCCGCAGCGAACCGCTTCCTGACCCTGGAGCTGTCCGCCATGGAAGCCGACGGCCAG
GGCAAGGTGGTATCGAGCCCGCGCCTCATCACGGCGGACCAGACCAAGGCCCTGATCGAGCAGGGTACCGAATACCCGTA
CTCGGTGACGGCCCCGAACGGCGCGACCACCATCGCCTTCAAGAAGGCGGTGCTGAAGCTGGAGGTCACGCCCCAGATCA
CGCCCGAGGGCAACATCATCCTCGACCTGGATGTGAACAAGGACAGCAAGGGAGAGACGACCACGCAGGGCGTCGCCATC
GACACGAACCACGTCAAGACGCAGGTTCTGGTGGAGAACGGCGGTACCGTGGTGATCGGCGGGATCTTCCGGTTGGAGGA
AACCAACCAGGAAAACAAGATCCCCCTGCTGGGAGACGTGCCGGTCGTCGGCAACCTCTTCAAAAACAGGACCCGTGAGT
CCACCAAGCGCGAAATGCTGGTGTTCATCACGCCGAAGGTGATTTCGGACAAAGGTCCGGTCCGTTAA

Upstream 100 bases:

>100_bases
GGATCACCGAGACGGCCGTTCAGCTGCGTGAAATAGTCCAGGACGCCACGGGTGACTGGATGGAGCGTCCTGCGACGCTG
GATCTCCAAGAGGGGAAGAA

Downstream 100 bases:

>100_bases
AAGCAAATGAAGGTGAACGAATGAAAGCATTGATGAGAGCCATCGCGTTGACGCTGGCTGCCACGCTTGCAGCGTGTGGA
GGAGGTGGCGGGAGCGGCGG

Product: type IV pilus secretin PilQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 715; Mature: 715

Protein sequence:

>715_residues
MIRTKWFGFRCRAALLAAAATLCSTWAHAQAAIESVTGAVQGGTEMVRIELSQPLGAVPSGFAIQAPARIALDFPNTTNG
TGKSLVEVNQGNLKSVNIVQAGDRSRVVLNLKQPTSYKAEVQGSALMVSLEPVSGGAVSNAAAPAVFAENRNTDVLPLRD
VDFRRGTDGAGRVIVGLANNQVGVDLRKQGNNLVVEFLKSSLPEGLRRRLDVTDFGTPVRTVTTTTQGERVRMTIEPIGE
WEHSAYQSDNQFVVEVRQKKVDLNKLSQGPGFSGEKLSLNFQNIEVRSLLQVIADFTNFNIVTSDTVTGALTLRLKDVPW
DQALQIIMDAKGLGMRKSGTVLWIAPKDEIDARTKKDYEAALAIQKLEPLRTQAFQLNYAKAADMVTQLANNSTGSTGTS
TRFLSERGSAIAEPRTNQLFVTDTPSKLEEVRQLLSTLDVAVRQVMIEARIVEARDTFGRSLGVRLGGADLRANRGGDGG
YSVGGNNRLAIGTSYNNAVASSGAGGTVATGSDAAGSTFVNLPAALSSGASFGNFALTLFNSAANRFLTLELSAMEADGQ
GKVVSSPRLITADQTKALIEQGTEYPYSVTAPNGATTIAFKKAVLKLEVTPQITPEGNIILDLDVNKDSKGETTTQGVAI
DTNHVKTQVLVENGGTVVIGGIFRLEETNQENKIPLLGDVPVVGNLFKNRTRESTKREMLVFITPKVISDKGPVR

Sequences:

>Translated_715_residues
MIRTKWFGFRCRAALLAAAATLCSTWAHAQAAIESVTGAVQGGTEMVRIELSQPLGAVPSGFAIQAPARIALDFPNTTNG
TGKSLVEVNQGNLKSVNIVQAGDRSRVVLNLKQPTSYKAEVQGSALMVSLEPVSGGAVSNAAAPAVFAENRNTDVLPLRD
VDFRRGTDGAGRVIVGLANNQVGVDLRKQGNNLVVEFLKSSLPEGLRRRLDVTDFGTPVRTVTTTTQGERVRMTIEPIGE
WEHSAYQSDNQFVVEVRQKKVDLNKLSQGPGFSGEKLSLNFQNIEVRSLLQVIADFTNFNIVTSDTVTGALTLRLKDVPW
DQALQIIMDAKGLGMRKSGTVLWIAPKDEIDARTKKDYEAALAIQKLEPLRTQAFQLNYAKAADMVTQLANNSTGSTGTS
TRFLSERGSAIAEPRTNQLFVTDTPSKLEEVRQLLSTLDVAVRQVMIEARIVEARDTFGRSLGVRLGGADLRANRGGDGG
YSVGGNNRLAIGTSYNNAVASSGAGGTVATGSDAAGSTFVNLPAALSSGASFGNFALTLFNSAANRFLTLELSAMEADGQ
GKVVSSPRLITADQTKALIEQGTEYPYSVTAPNGATTIAFKKAVLKLEVTPQITPEGNIILDLDVNKDSKGETTTQGVAI
DTNHVKTQVLVENGGTVVIGGIFRLEETNQENKIPLLGDVPVVGNLFKNRTRESTKREMLVFITPKVISDKGPVR
>Mature_715_residues
MIRTKWFGFRCRAALLAAAATLCSTWAHAQAAIESVTGAVQGGTEMVRIELSQPLGAVPSGFAIQAPARIALDFPNTTNG
TGKSLVEVNQGNLKSVNIVQAGDRSRVVLNLKQPTSYKAEVQGSALMVSLEPVSGGAVSNAAAPAVFAENRNTDVLPLRD
VDFRRGTDGAGRVIVGLANNQVGVDLRKQGNNLVVEFLKSSLPEGLRRRLDVTDFGTPVRTVTTTTQGERVRMTIEPIGE
WEHSAYQSDNQFVVEVRQKKVDLNKLSQGPGFSGEKLSLNFQNIEVRSLLQVIADFTNFNIVTSDTVTGALTLRLKDVPW
DQALQIIMDAKGLGMRKSGTVLWIAPKDEIDARTKKDYEAALAIQKLEPLRTQAFQLNYAKAADMVTQLANNSTGSTGTS
TRFLSERGSAIAEPRTNQLFVTDTPSKLEEVRQLLSTLDVAVRQVMIEARIVEARDTFGRSLGVRLGGADLRANRGGDGG
YSVGGNNRLAIGTSYNNAVASSGAGGTVATGSDAAGSTFVNLPAALSSGASFGNFALTLFNSAANRFLTLELSAMEADGQ
GKVVSSPRLITADQTKALIEQGTEYPYSVTAPNGATTIAFKKAVLKLEVTPQITPEGNIILDLDVNKDSKGETTTQGVAI
DTNHVKTQVLVENGGTVVIGGIFRLEETNQENKIPLLGDVPVVGNLFKNRTRESTKREMLVFITPKVISDKGPVR

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=445, Percent_Identity=32.3595505617978, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI87082242, Length=380, Percent_Identity=27.8947368421053, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 76435; Mature: 76435

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTKWFGFRCRAALLAAAATLCSTWAHAQAAIESVTGAVQGGTEMVRIELSQPLGAVPS
CCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCC
GFAIQAPARIALDFPNTTNGTGKSLVEVNQGNLKSVNIVQAGDRSRVVLNLKQPTSYKAE
CEEEECCCEEEEECCCCCCCCCCEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCCEEE
VQGSALMVSLEPVSGGAVSNAAAPAVFAENRNTDVLPLRDVDFRRGTDGAGRVIVGLANN
ECCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCCCCCEEEEEECCC
QVGVDLRKQGNNLVVEFLKSSLPEGLRRRLDVTDFGTPVRTVTTTTQGERVRMTIEPIGE
CCCEEHHHCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEECCCCC
WEHSAYQSDNQFVVEVRQKKVDLNKLSQGPGFSGEKLSLNFQNIEVRSLLQVIADFTNFN
CCHHHHCCCCEEEEEEEHHHCCHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCE
IVTSDTVTGALTLRLKDVPWDQALQIIMDAKGLGMRKSGTVLWIAPKDEIDARTKKDYEA
EEECCCCEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHH
ALAIQKLEPLRTQAFQLNYAKAADMVTQLANNSTGSTGTSTRFLSERGSAIAEPRTNQLF
HHHHHHHCCHHHHHEEECHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCEEE
VTDTPSKLEEVRQLLSTLDVAVRQVMIEARIVEARDTFGRSLGVRLGGADLRANRGGDGG
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHCCCCCCEEECCCEEECCCCCCCC
YSVGGNNRLAIGTSYNNAVASSGAGGTVATGSDAAGSTFVNLPAALSSGASFGNFALTLF
EECCCCCEEEEECCCCCHHCCCCCCCEEECCCCCCCCEEEECCHHHHCCCCCCCEEEEEE
NSAANRFLTLELSAMEADGQGKVVSSPRLITADQTKALIEQGTEYPYSVTAPNGATTIAF
HHCCCEEEEEEEEEECCCCCCCEECCCEEEECHHHHHHHHCCCCCCEEEECCCCCEEEEE
KKAVLKLEVTPQITPEGNIILDLDVNKDSKGETTTQGVAIDTNHVKTQVLVENGGTVVIG
EEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCEEEEEEECCCEEEEE
GIFRLEETNQENKIPLLGDVPVVGNLFKNRTRESTKREMLVFITPKVISDKGPVR
EEEEEECCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCEEEEECCCEECCCCCCC
>Mature Secondary Structure
MIRTKWFGFRCRAALLAAAATLCSTWAHAQAAIESVTGAVQGGTEMVRIELSQPLGAVPS
CCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCC
GFAIQAPARIALDFPNTTNGTGKSLVEVNQGNLKSVNIVQAGDRSRVVLNLKQPTSYKAE
CEEEECCCEEEEECCCCCCCCCCEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCCEEE
VQGSALMVSLEPVSGGAVSNAAAPAVFAENRNTDVLPLRDVDFRRGTDGAGRVIVGLANN
ECCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCCCCCEEEEEECCC
QVGVDLRKQGNNLVVEFLKSSLPEGLRRRLDVTDFGTPVRTVTTTTQGERVRMTIEPIGE
CCCEEHHHCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEECCCCC
WEHSAYQSDNQFVVEVRQKKVDLNKLSQGPGFSGEKLSLNFQNIEVRSLLQVIADFTNFN
CCHHHHCCCCEEEEEEEHHHCCHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCE
IVTSDTVTGALTLRLKDVPWDQALQIIMDAKGLGMRKSGTVLWIAPKDEIDARTKKDYEA
EEECCCCEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHH
ALAIQKLEPLRTQAFQLNYAKAADMVTQLANNSTGSTGTSTRFLSERGSAIAEPRTNQLF
HHHHHHHCCHHHHHEEECHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCEEE
VTDTPSKLEEVRQLLSTLDVAVRQVMIEARIVEARDTFGRSLGVRLGGADLRANRGGDGG
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHCCCCCCEEECCCEEECCCCCCCC
YSVGGNNRLAIGTSYNNAVASSGAGGTVATGSDAAGSTFVNLPAALSSGASFGNFALTLF
EECCCCCEEEEECCCCCHHCCCCCCCEEECCCCCCCCEEEECCHHHHCCCCCCCEEEEEE
NSAANRFLTLELSAMEADGQGKVVSSPRLITADQTKALIEQGTEYPYSVTAPNGATTIAF
HHCCCEEEEEEEEEECCCCCCCEECCCEEEECHHHHHHHHCCCCCCEEEECCCCCEEEEE
KKAVLKLEVTPQITPEGNIILDLDVNKDSKGETTTQGVAIDTNHVKTQVLVENGGTVVIG
EEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCEEEEEEECCCEEEEE
GIFRLEETNQENKIPLLGDVPVVGNLFKNRTRESTKREMLVFITPKVISDKGPVR
EEEEEECCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCEEEEECCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]