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The map label for this gene is xanB [H]

Identifier: 120609642

GI number: 120609642

Start: 1033389

End: 1034906

Strand: Direct

Name: xanB [H]

Synonym: Aave_0948

Alternate gene names: 120609642

Gene position: 1033389-1034906 (Clockwise)

Preceding gene: 120609641

Following gene: 120609643

Centisome position: 19.31

GC content: 64.76

Gene sequence:

>1518_bases
ATGACCGTGGCCGCTTTACCCCGATTGCTGCCGGTGGTGCTTTGTGGGGGCGTGGGCTCGCGCCTGTGGCCGCTCTCGCG
TGAAACCTATCCCAAGCAGTTCCTTGCGCTGACCGGCGAGCGGTCCATGCTCCAGGAAACCGTGCTGCGGCTGCGGGAAC
CGCTGCCTGGTATCTGTGTGGACGATGCCCCTGTGCTGGTCTGCAACAGCGAACACCGTTTCGTCGCTGCCGAGCAGTTG
AAGGCGATCGGCATGGAGGGCGCACGGATTCTGCTGGAGCCCGTGGGCCGCAATACCGCGCCGGCCCTCACCATCGCTGC
GCTACAGGCGCTCGAAAACGACCAATCCGACGACGATCCCGTGCTGTTGGCGATGCCCGCGGACCATGTGATTGCGGATG
GAGGTGCTTTCCGGCTGGCCGTCCAGCGTGCCTTTCCGTTCGCGGCGGAGGGCGGTATCGTCACCTTCGGCATCGTGCCG
GATCATCCGGAAACAGGGTATGGCTACATCCGTTGCGTACCGCTGGCGCATGGGAACTCTTCAGGCCTGGATAAGGCTGC
GCAAGTGCGCCGTGTCGCCGATTTTGTCGAGAAGCCGGACGGAGAGACGGCATCCGCGTATCTCGCCAGCGGCCAGTACT
TGTGGAATGGCGGTCTTTTCATGGTGCGTGCAGGCCGGTGGCTGGCGGCTGTGCGTGCATGCCGGCCCGACATCCTGGAG
GCATGCTCCGACGCCATGCGCGGCGCTGTGCGCGATCTGGATTTCATCCGGCCTGCCGAACCGGCCTTCGAAGCGTGTCC
CACGGATTCCATCGATTACGCGGTGATGGAACGCCTGCCGTCCATGCCGCAACTGGATATGCACGCTTATGTCGTGCCCC
TGGACGCGGGATGGTCCGACCTGGGGGCCTGGGATGCTCTCTGGGAAACACTCGAGCGCGATCCTGAGGGGAACGCCGCT
GTGGGCCACGTGGTGCAGCATGGCTGCCGCGACACACTGCTGTATGGCTCGAGCCGGCTGGTCGCCGGGGTCGGCCTGGA
CCATGTCGTCGTGGTGGAAACCCCCGATGCGGTGCTGGTGGCCGACAAACGCCGTACACAGGAAGTGAAGCACGTGGTGG
CCCTGCTGGCGCGTGCAGGGAACGGGTTGGCCCAGCACCACCGAAAGGTGCATCGTCCCTGGGGGTGGTACGACGCCATT
GACAGTGGGGCCCGGTTCCAGGTCAAGCGCATCGTCGTCAATCCGGGCGCGCGCCTCAGCCTGCAAATGCACCGGCACCG
CGCGGAGCACTGGGTGGTGGTCAGTGGCATGGCGGAAATCACCAACGGAGACGACACCTACGTGCTCGGACCCAACCAAT
CCACCTACATTCCCGTGGGCACGGCCCACCGGCTTGCCAACCCCGGGCAGATGCCGCTCGAGATTATCGAGGTCCAGTCG
GGAGATTATCTCGGCGAGGATGACATCGTGCGACTCGATGACATCTATGGCCGCTCGTCCTCTGGAGGCGGCAACTGA

Upstream 100 bases:

>100_bases
GCATCGAACGGGACGTCCGCCGCCTGAACCAGCGCCTCGCGTTGCTCGAGGCCGATGCGGAGGAATTTCGTGATCGCCTC
CGTGCCGACGTGCCCGACGC

Downstream 100 bases:

>100_bases
ACGCTGGCGCAGCCTGTTGAATTCTTGCTGAAGTAGATGATGAACCTGGAAAATGCAACCATTGCCGTGATCGGCCTGGG
CTACGTGGGCTTGCCACTGG

Product: mannose-1-phosphate guanylyltransferase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MTVAALPRLLPVVLCGGVGSRLWPLSRETYPKQFLALTGERSMLQETVLRLREPLPGICVDDAPVLVCNSEHRFVAAEQL
KAIGMEGARILLEPVGRNTAPALTIAALQALENDQSDDDPVLLAMPADHVIADGGAFRLAVQRAFPFAAEGGIVTFGIVP
DHPETGYGYIRCVPLAHGNSSGLDKAAQVRRVADFVEKPDGETASAYLASGQYLWNGGLFMVRAGRWLAAVRACRPDILE
ACSDAMRGAVRDLDFIRPAEPAFEACPTDSIDYAVMERLPSMPQLDMHAYVVPLDAGWSDLGAWDALWETLERDPEGNAA
VGHVVQHGCRDTLLYGSSRLVAGVGLDHVVVVETPDAVLVADKRRTQEVKHVVALLARAGNGLAQHHRKVHRPWGWYDAI
DSGARFQVKRIVVNPGARLSLQMHRHRAEHWVVVSGMAEITNGDDTYVLGPNQSTYIPVGTAHRLANPGQMPLEIIEVQS
GDYLGEDDIVRLDDIYGRSSSGGGN

Sequences:

>Translated_505_residues
MTVAALPRLLPVVLCGGVGSRLWPLSRETYPKQFLALTGERSMLQETVLRLREPLPGICVDDAPVLVCNSEHRFVAAEQL
KAIGMEGARILLEPVGRNTAPALTIAALQALENDQSDDDPVLLAMPADHVIADGGAFRLAVQRAFPFAAEGGIVTFGIVP
DHPETGYGYIRCVPLAHGNSSGLDKAAQVRRVADFVEKPDGETASAYLASGQYLWNGGLFMVRAGRWLAAVRACRPDILE
ACSDAMRGAVRDLDFIRPAEPAFEACPTDSIDYAVMERLPSMPQLDMHAYVVPLDAGWSDLGAWDALWETLERDPEGNAA
VGHVVQHGCRDTLLYGSSRLVAGVGLDHVVVVETPDAVLVADKRRTQEVKHVVALLARAGNGLAQHHRKVHRPWGWYDAI
DSGARFQVKRIVVNPGARLSLQMHRHRAEHWVVVSGMAEITNGDDTYVLGPNQSTYIPVGTAHRLANPGQMPLEIIEVQS
GDYLGEDDIVRLDDIYGRSSSGGGN
>Mature_504_residues
TVAALPRLLPVVLCGGVGSRLWPLSRETYPKQFLALTGERSMLQETVLRLREPLPGICVDDAPVLVCNSEHRFVAAEQLK
AIGMEGARILLEPVGRNTAPALTIAALQALENDQSDDDPVLLAMPADHVIADGGAFRLAVQRAFPFAAEGGIVTFGIVPD
HPETGYGYIRCVPLAHGNSSGLDKAAQVRRVADFVEKPDGETASAYLASGQYLWNGGLFMVRAGRWLAAVRACRPDILEA
CSDAMRGAVRDLDFIRPAEPAFEACPTDSIDYAVMERLPSMPQLDMHAYVVPLDAGWSDLGAWDALWETLERDPEGNAAV
GHVVQHGCRDTLLYGSSRLVAGVGLDHVVVVETPDAVLVADKRRTQEVKHVVALLARAGNGLAQHHRKVHRPWGWYDAID
SGARFQVKRIVVNPGARLSLQMHRHRAEHWVVVSGMAEITNGDDTYVLGPNQSTYIPVGTAHRLANPGQMPLEIIEVQSG
DYLGEDDIVRLDDIYGRSSSGGGN

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=495, Percent_Identity=52.1212121212121, Blast_Score=498, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 54752; Mature: 54621

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVAALPRLLPVVLCGGVGSRLWPLSRETYPKQFLALTGERSMLQETVLRLREPLPGICV
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEECCCHHHHHHHHHHHHCCCCCCEE
DDAPVLVCNSEHRFVAAEQLKAIGMEGARILLEPVGRNTAPALTIAALQALENDQSDDDP
CCCCEEEECCCCCEEHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCC
VLLAMPADHVIADGGAFRLAVQRAFPFAAEGGIVTFGIVPDHPETGYGYIRCVPLAHGNS
EEEEECCCCEEECCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCC
SGLDKAAQVRRVADFVEKPDGETASAYLASGQYLWNGGLFMVRAGRWLAAVRACRPDILE
CCHHHHHHHHHHHHHHHCCCCCCHHHHEECCEEEEECCEEEEECCHHHHHHHHCCHHHHH
ACSDAMRGAVRDLDFIRPAEPAFEACPTDSIDYAVMERLPSMPQLDMHAYVVPLDAGWSD
HHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCCC
LGAWDALWETLERDPEGNAAVGHVVQHGCRDTLLYGSSRLVAGVGLDHVVVVETPDAVLV
CCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHEEECCCCEEEECCCCEEEEEECCCEEEE
ADKRRTQEVKHVVALLARAGNGLAQHHRKVHRPWGWYDAIDSGARFQVKRIVVNPGARLS
ECCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHCCCCCEEEEEEEECCCCEEE
LQMHRHRAEHWVVVSGMAEITNGDDTYVLGPNQSTYIPVGTAHRLANPGQMPLEIIEVQS
HHHHHCCCCEEEEEECHHHHCCCCCEEEECCCCCEEEECCHHHHCCCCCCCCEEEEEECC
GDYLGEDDIVRLDDIYGRSSSGGGN
CCCCCCCCEEEEHHHCCCCCCCCCC
>Mature Secondary Structure 
TVAALPRLLPVVLCGGVGSRLWPLSRETYPKQFLALTGERSMLQETVLRLREPLPGICV
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEECCCHHHHHHHHHHHHCCCCCCEE
DDAPVLVCNSEHRFVAAEQLKAIGMEGARILLEPVGRNTAPALTIAALQALENDQSDDDP
CCCCEEEECCCCCEEHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCC
VLLAMPADHVIADGGAFRLAVQRAFPFAAEGGIVTFGIVPDHPETGYGYIRCVPLAHGNS
EEEEECCCCEEECCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCC
SGLDKAAQVRRVADFVEKPDGETASAYLASGQYLWNGGLFMVRAGRWLAAVRACRPDILE
CCHHHHHHHHHHHHHHHCCCCCCHHHHEECCEEEEECCEEEEECCHHHHHHHHCCHHHHH
ACSDAMRGAVRDLDFIRPAEPAFEACPTDSIDYAVMERLPSMPQLDMHAYVVPLDAGWSD
HHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCCC
LGAWDALWETLERDPEGNAAVGHVVQHGCRDTLLYGSSRLVAGVGLDHVVVVETPDAVLV
CCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHEEECCCCEEEECCCCEEEEEECCCEEEE
ADKRRTQEVKHVVALLARAGNGLAQHHRKVHRPWGWYDAIDSGARFQVKRIVVNPGARLS
ECCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHCCCCCEEEEEEEECCCCEEE
LQMHRHRAEHWVVVSGMAEITNGDDTYVLGPNQSTYIPVGTAHRLANPGQMPLEIIEVQS
HHHHHCCCCEEEEEECHHHHCCCCCEEEECCCCCEEEECCHHHHCCCCCCCCEEEEEECC
GDYLGEDDIVRLDDIYGRSSSGGGN
CCCCCCCCEEEEHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]