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The map label for this gene is dppC [H]

Identifier: 120609631

GI number: 120609631

Start: 1019552

End: 1020499

Strand: Direct

Name: dppC [H]

Synonym: Aave_0937

Alternate gene names: 120609631

Gene position: 1019552-1020499 (Clockwise)

Preceding gene: 120609630

Following gene: 120609632

Centisome position: 19.05

GC content: 67.19

Gene sequence:

>948_bases
ATGCCGTTCCGCTCCACGCTTTTCCCGAATCGCACGATGAAAAAAACGCTTTTCCGATGGTTCGACAGCGATGTCGGCTA
CAGCTTCCGCACTTCGCCCGTCGCCATCGGCGCCGCGGCGATCGCGGTGGTGTGCGTGTTCTGCTCGCTGTTCGCGGGCT
GGGTGGCGCCGCACAATCCGTTCGATCTCAACACGCTCGAATTGAGCGATGCCCGGCTGCCGCCGGCGTGGAGCGACGGA
GGCTCCTGGAAGTACCCGTTCGGCACGGACGACCAGGGGCGCGACATTCTCTCGGCGCTGATCTATGGCGCGCGCATTTC
GCTCATCGTCGGCCTGGCATCCGTCGCGCTGTCGGTGGTGGTGGGGGTGGCGCTCGGGCTGCTGGCGGGCTTCAAGGGGG
GCTGGATCGACGCGGTACTCATGCGCCTGTGCGACGTGATGCTGTCCTTTCCCGCGATTCTCGTGGCGCTGCTGATCGCC
GGCGTGGGGCGCGCGGTGTTCCCGAACGCGCACGAGTCGCTGGCCTTCGGGGTGCTGATCCTCTCCATCTCGCTCACGGG
CTGGGTGCAGTACGCACGCACCGTGCGCGGGTCCACCCTGGTGGAGCGCAACAAGGAATACGTGCAGGCGGCCCGCGTGA
CGGGCGTGTCGTCCCTGCGCATCATGCGCCGCCACGTGCTGCCCAATGTGCTCGGGCCGGTGATGGTGCTGGCCACGATC
CAGGTGGCGACGGCCATCATCACCGAGGCCACGCTGTCCTTCCTGGGAGTGGGCGCGCCGCCCACTTCGCCGTCGCTCGG
CACGCTGATCCGCATCGGCAACGACTATCTGTTCTCGGGCGAATGGTGGATCACGGTGTTCCCGGGCGTGATGCTGGTGC
TGATCGCGCTCTCCGTGAACCTGCTGGGGGACTGGCTGCGCGATGCGCTGAACCCCCGCCTCCGCTAG

Upstream 100 bases:

>100_bases
TCGCGCAAGGTGGCGCTGGTGCAGATGGCCGACAACTTCATGCCGTTCAAGTGGATGAGCCTCGCGAAGTGATGCCCTGA
TCCGTTCCGTCCGCGTGGAG

Downstream 100 bases:

>100_bases
AAATGGAGCACACCCCCCTGAGCGGCTGCGCCGCTTCCCCCCGCTCTCGCCGCGCTGCGCGCGGCGGGCAGGGGGACGAC
GCCAGCGGCCTGGCGAAGCC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MPFRSTLFPNRTMKKTLFRWFDSDVGYSFRTSPVAIGAAAIAVVCVFCSLFAGWVAPHNPFDLNTLELSDARLPPAWSDG
GSWKYPFGTDDQGRDILSALIYGARISLIVGLASVALSVVVGVALGLLAGFKGGWIDAVLMRLCDVMLSFPAILVALLIA
GVGRAVFPNAHESLAFGVLILSISLTGWVQYARTVRGSTLVERNKEYVQAARVTGVSSLRIMRRHVLPNVLGPVMVLATI
QVATAIITEATLSFLGVGAPPTSPSLGTLIRIGNDYLFSGEWWITVFPGVMLVLIALSVNLLGDWLRDALNPRLR

Sequences:

>Translated_315_residues
MPFRSTLFPNRTMKKTLFRWFDSDVGYSFRTSPVAIGAAAIAVVCVFCSLFAGWVAPHNPFDLNTLELSDARLPPAWSDG
GSWKYPFGTDDQGRDILSALIYGARISLIVGLASVALSVVVGVALGLLAGFKGGWIDAVLMRLCDVMLSFPAILVALLIA
GVGRAVFPNAHESLAFGVLILSISLTGWVQYARTVRGSTLVERNKEYVQAARVTGVSSLRIMRRHVLPNVLGPVMVLATI
QVATAIITEATLSFLGVGAPPTSPSLGTLIRIGNDYLFSGEWWITVFPGVMLVLIALSVNLLGDWLRDALNPRLR
>Mature_314_residues
PFRSTLFPNRTMKKTLFRWFDSDVGYSFRTSPVAIGAAAIAVVCVFCSLFAGWVAPHNPFDLNTLELSDARLPPAWSDGG
SWKYPFGTDDQGRDILSALIYGARISLIVGLASVALSVVVGVALGLLAGFKGGWIDAVLMRLCDVMLSFPAILVALLIAG
VGRAVFPNAHESLAFGVLILSISLTGWVQYARTVRGSTLVERNKEYVQAARVTGVSSLRIMRRHVLPNVLGPVMVLATIQ
VATAIITEATLSFLGVGAPPTSPSLGTLIRIGNDYLFSGEWWITVFPGVMLVLIALSVNLLGDWLRDALNPRLR

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=292, Percent_Identity=41.0958904109589, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI1787054, Length=291, Percent_Identity=36.426116838488, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1787760, Length=304, Percent_Identity=35.1973684210526, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787498, Length=232, Percent_Identity=40.0862068965517, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789889, Length=256, Percent_Identity=31.640625, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1787549, Length=313, Percent_Identity=30.9904153354633, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788505, Length=226, Percent_Identity=35.8407079646018, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33960; Mature: 33829

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFRSTLFPNRTMKKTLFRWFDSDVGYSFRTSPVAIGAAAIAVVCVFCSLFAGWVAPHNP
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
FDLNTLELSDARLPPAWSDGGSWKYPFGTDDQGRDILSALIYGARISLIVGLASVALSVV
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGVALGLLAGFKGGWIDAVLMRLCDVMLSFPAILVALLIAGVGRAVFPNAHESLAFGVLI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHH
LSISLTGWVQYARTVRGSTLVERNKEYVQAARVTGVSSLRIMRRHVLPNVLGPVMVLATI
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVATAIITEATLSFLGVGAPPTSPSLGTLIRIGNDYLFSGEWWITVFPGVMLVLIALSVN
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEECCCEEECCCCHHHHHHHHHHHHHHHHHH
LLGDWLRDALNPRLR
HHHHHHHHHCCCCCC
>Mature Secondary Structure 
PFRSTLFPNRTMKKTLFRWFDSDVGYSFRTSPVAIGAAAIAVVCVFCSLFAGWVAPHNP
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
FDLNTLELSDARLPPAWSDGGSWKYPFGTDDQGRDILSALIYGARISLIVGLASVALSVV
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGVALGLLAGFKGGWIDAVLMRLCDVMLSFPAILVALLIAGVGRAVFPNAHESLAFGVLI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHH
LSISLTGWVQYARTVRGSTLVERNKEYVQAARVTGVSSLRIMRRHVLPNVLGPVMVLATI
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVATAIITEATLSFLGVGAPPTSPSLGTLIRIGNDYLFSGEWWITVFPGVMLVLIALSVN
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEECCCEEECCCCHHHHHHHHHHHHHHHHHH
LLGDWLRDALNPRLR
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]