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The map label for this gene is visC [H]

Identifier: 120609579

GI number: 120609579

Start: 961735

End: 962961

Strand: Reverse

Name: visC [H]

Synonym: Aave_0885

Alternate gene names: 120609579

Gene position: 962961-961735 (Counterclockwise)

Preceding gene: 120609582

Following gene: 120609578

Centisome position: 17.99

GC content: 74.57

Gene sequence:

>1227_bases
ATGGGGAAAGGGAAGGCGGCGATTGTGCCTTCGCACGGCAGAGCACGGGCCGGCTCCTACAATGGCCGCATGGCGCAAAC
CTTCGATGTCTGTATTCGCGGCGCTGGCGTGGTGGGCCGCGCGCTGTCCCTGCTTCTCGCGCGCGAGCGCCTGCGCGTGG
CCCTGGTCCCGGGGCCGGCCCCGGCGGCCGAGGGCGCCGACGTGCGGGCCTACGCGCTCAACGCCGCCTCGCGCACGCTC
CTGGAATCCGTGCGCAGCTGGCCCGACGCGGAGCACGCCACGCCGGTGCTGCGCATGGACGTGCACGGCGACATGGGCGG
CGAGGTCACCTTCGACGCCCGGCGCCATCCCGCCACCGGGGCGCTGGCCTGGATCGTCGATGTGCCCGCGCTGGAATCCC
GGCTGGCCGACGCCGTGCGCTTCCAGCCGCAGGTGGAAGTGGTCGATGCGCCCGTGCAGGCCGCGCTCACGGTGGTCTGC
GAAGGCCGCGCGAGCCGCACGCGCGAGGAATTCGGCGTGCGCTACACCGAAGTGCCCTACGGCCAGCACGCGGTGGCCAC
GCGCCTGCGCTGCGAGCGGCCCCACGGCCAGGTGGCGCGCCAGTGGTTCCTGCCCGACGGCATCCTGGCCTTCCTGCCCC
TGGGAGGGCCGGAGGGGAACTCCGTGGCCGTGGTGTGGTCCGTACGGCAGGACGAGGCGCAGCGCCTCCTGGCCATGGAA
CCCTCCGATTTCGAACAACGCATCCGCTCCGCCAGCCTGGACACGCTGGGCGCCCTCACGCTGGACGCCCCCCGGGCCGC
GTGGCCGCTGCAGCAGGCGCAGGCCGACCGCTGGTGCGGACCGATGCCGGCCGCCGCGGGCAACGCCCCCGCGTCCGCGA
AGGCACCGGCCCGCAGCTGGGCGCTGGCGGGCGATGCCGCGCACACCGTCCATCCGCTGGCCGGCCAGGGGCTGAACCTG
GGCCTGGCCGATGCCCTGGCCCTGGCCCGCGTGCTGCGCGAGCGCGATTACTGGCGCGGCGTCGCGGACCAGCGCCTGCT
GCGCCGCTACGAGCGCGAGCGCAAGGCCGCGCTGCTGCCGATGGGCTGGGCCATGGACGGCCTGCAGCAGCTTTTCTCGC
GCCACGAGGGTCCCGTGCCCTGGCTGCGCAACTGGGGCATGCGCGGATTCGAGCGCAGCGGCCCCCTCAAGGACTGGGTG
ACGCGCCAGGCCATGGGCCTGGGCTGA

Upstream 100 bases:

>100_bases
GGCCGCGCAGGACTTGACGGGATGGATGAACAGGCGGGAGATGGTGCCGCCCAGGTCGCGGTCGGTGCGGAAGGTCACGC
GGAGGTCTCCGGGTAGCGCG

Downstream 100 bases:

>100_bases
CGGCCCGCCGCATCCCGGGATGCGGCGGCCGCCGTGCCGCCCATTCCCCAGAGATTCACGCATCACGAAGGAGCACCATG
AAACTGATCCCCGCCCTGCT

Product: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MGKGKAAIVPSHGRARAGSYNGRMAQTFDVCIRGAGVVGRALSLLLARERLRVALVPGPAPAAEGADVRAYALNAASRTL
LESVRSWPDAEHATPVLRMDVHGDMGGEVTFDARRHPATGALAWIVDVPALESRLADAVRFQPQVEVVDAPVQAALTVVC
EGRASRTREEFGVRYTEVPYGQHAVATRLRCERPHGQVARQWFLPDGILAFLPLGGPEGNSVAVVWSVRQDEAQRLLAME
PSDFEQRIRSASLDTLGALTLDAPRAAWPLQQAQADRWCGPMPAAAGNAPASAKAPARSWALAGDAAHTVHPLAGQGLNL
GLADALALARVLRERDYWRGVADQRLLRRYERERKAALLPMGWAMDGLQQLFSRHEGPVPWLRNWGMRGFERSGPLKDWV
TRQAMGLG

Sequences:

>Translated_408_residues
MGKGKAAIVPSHGRARAGSYNGRMAQTFDVCIRGAGVVGRALSLLLARERLRVALVPGPAPAAEGADVRAYALNAASRTL
LESVRSWPDAEHATPVLRMDVHGDMGGEVTFDARRHPATGALAWIVDVPALESRLADAVRFQPQVEVVDAPVQAALTVVC
EGRASRTREEFGVRYTEVPYGQHAVATRLRCERPHGQVARQWFLPDGILAFLPLGGPEGNSVAVVWSVRQDEAQRLLAME
PSDFEQRIRSASLDTLGALTLDAPRAAWPLQQAQADRWCGPMPAAAGNAPASAKAPARSWALAGDAAHTVHPLAGQGLNL
GLADALALARVLRERDYWRGVADQRLLRRYERERKAALLPMGWAMDGLQQLFSRHEGPVPWLRNWGMRGFERSGPLKDWV
TRQAMGLG
>Mature_407_residues
GKGKAAIVPSHGRARAGSYNGRMAQTFDVCIRGAGVVGRALSLLLARERLRVALVPGPAPAAEGADVRAYALNAASRTLL
ESVRSWPDAEHATPVLRMDVHGDMGGEVTFDARRHPATGALAWIVDVPALESRLADAVRFQPQVEVVDAPVQAALTVVCE
GRASRTREEFGVRYTEVPYGQHAVATRLRCERPHGQVARQWFLPDGILAFLPLGGPEGNSVAVVWSVRQDEAQRLLAMEP
SDFEQRIRSASLDTLGALTLDAPRAAWPLQQAQADRWCGPMPAAAGNAPASAKAPARSWALAGDAAHTVHPLAGQGLNLG
LADALALARVLRERDYWRGVADQRLLRRYERERKAALLPMGWAMDGLQQLFSRHEGPVPWLRNWGMRGFERSGPLKDWVT
RQAMGLG

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=361, Percent_Identity=28.2548476454294, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI32967307, Length=358, Percent_Identity=28.4916201117318, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1789273, Length=413, Percent_Identity=31.2348668280872, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786883, Length=412, Percent_Identity=30.5825242718447, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1789274, Length=410, Percent_Identity=27.0731707317073, Blast_Score=99, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6321694, Length=375, Percent_Identity=24.2666666666667, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920760, Length=447, Percent_Identity=26.8456375838926, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 44283; Mature: 44152

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKGKAAIVPSHGRARAGSYNGRMAQTFDVCIRGAGVVGRALSLLLARERLRVALVPGPA
CCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCEEEEEECCCC
PAAEGADVRAYALNAASRTLLESVRSWPDAEHATPVLRMDVHGDMGGEVTFDARRHPATG
CCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCCC
ALAWIVDVPALESRLADAVRFQPQVEVVDAPVQAALTVVCEGRASRTREEFGVRYTEVPY
EEEEEEECHHHHHHHHHHHHCCCCEEEECCCHHHHHHHEECCCHHHHHHHHCCEEEECCC
GQHAVATRLRCERPHGQVARQWFLPDGILAFLPLGGPEGNSVAVVWSVRQDEAQRLLAME
CCHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHCCC
PSDFEQRIRSASLDTLGALTLDAPRAAWPLQQAQADRWCGPMPAAAGNAPASAKAPARSW
CCHHHHHHHHCCCHHHCEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHH
ALAGDAAHTVHPLAGQGLNLGLADALALARVLRERDYWRGVADQRLLRRYERERKAALLP
EECCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEECC
MGWAMDGLQQLFSRHEGPVPWLRNWGMRGFERSGPLKDWVTRQAMGLG
CHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
GKGKAAIVPSHGRARAGSYNGRMAQTFDVCIRGAGVVGRALSLLLARERLRVALVPGPA
CCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCEEEEEECCCC
PAAEGADVRAYALNAASRTLLESVRSWPDAEHATPVLRMDVHGDMGGEVTFDARRHPATG
CCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCCC
ALAWIVDVPALESRLADAVRFQPQVEVVDAPVQAALTVVCEGRASRTREEFGVRYTEVPY
EEEEEEECHHHHHHHHHHHHCCCCEEEECCCHHHHHHHEECCCHHHHHHHHCCEEEECCC
GQHAVATRLRCERPHGQVARQWFLPDGILAFLPLGGPEGNSVAVVWSVRQDEAQRLLAME
CCHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHCCC
PSDFEQRIRSASLDTLGALTLDAPRAAWPLQQAQADRWCGPMPAAAGNAPASAKAPARSW
CCHHHHHHHHCCCHHHCEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHH
ALAGDAAHTVHPLAGQGLNLGLADALALARVLRERDYWRGVADQRLLRRYERERKAALLP
EECCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEECC
MGWAMDGLQQLFSRHEGPVPWLRNWGMRGFERSGPLKDWVTRQAMGLG
CHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]