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The map label for this gene is gmhA [H]

Identifier: 120609331

GI number: 120609331

Start: 681503

End: 682105

Strand: Direct

Name: gmhA [H]

Synonym: Aave_0631

Alternate gene names: 120609331

Gene position: 681503-682105 (Clockwise)

Preceding gene: 120609330

Following gene: 120609332

Centisome position: 12.73

GC content: 71.64

Gene sequence:

>603_bases
ATGCTCGAGCAACGCATCCAACAGCATTTCATCGATAGCGCGGACCTCAAGTACCAGGCCGCGCAACTCCTCAGTCAACC
CATCGGGGCGGCCGTGCAGGCCATCCTGGCGTGCGTCACGAGCGGCGCCAAGGTCCTGGCCTGCGGCAGCGGCGCTGCCT
CCGCGCAGGCGCGGCAGTTCGCGGCGCTCTGCGTGGCCGGCTTCGAGCGGGAGCGGCCCGAACTGGCGGCCGTCGCGCTC
GAGCCTGACGCGCTCTGGTCCGCGCCCGGCATGCCCGGTGGCGACGCGCAGGTGCTGGCCCGGCAGGTGAGGGCGCTGGG
CCAGGCGGGGGACGTGCTGCTCGCCATGGCCGACGGCAGCGCGGCCACCGATGCCGCCCTGGTGGAAGCCATCCAGTCCG
CGCACGAGCGGGACATGACCGTGATCGCCCTCACTGGCCGGGGCGGCGCAGCGCTGGCCGGGCTGCTGCGCGAGACGGAC
GTGCTGATCGAGGTGCCGCACGACCGCGCGGCCCGCGTGCGCGAAGTGCATGCGCTGGTGCTGCACTGCCTGTGCGATGG
GGTGGATGCCCAGTTATTTGGTGAACAGGAGATACCGCTATGA

Upstream 100 bases:

>100_bases
GGCTGCAGGCCGCGTTCGATGCCGGCTAGCGCGGCGGTCGCCTGCCGCGCCAACGCCTTGCTACCGAAGCGGCAACACCC
GGGGGGTATCATCGGCGTAC

Downstream 100 bases:

>100_bases
CCTTGCAGACCTTGACCCGAACCACTGGCGCCGTGCTGGCCGCCGTCGCGCTGGGAACCGTGCTTTCGGCATGCGCCCCG
CTGATGATCGGCGGTGCCGC

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MLEQRIQQHFIDSADLKYQAAQLLSQPIGAAVQAILACVTSGAKVLACGSGAASAQARQFAALCVAGFERERPELAAVAL
EPDALWSAPGMPGGDAQVLARQVRALGQAGDVLLAMADGSAATDAALVEAIQSAHERDMTVIALTGRGGAALAGLLRETD
VLIEVPHDRAARVREVHALVLHCLCDGVDAQLFGEQEIPL

Sequences:

>Translated_200_residues
MLEQRIQQHFIDSADLKYQAAQLLSQPIGAAVQAILACVTSGAKVLACGSGAASAQARQFAALCVAGFERERPELAAVAL
EPDALWSAPGMPGGDAQVLARQVRALGQAGDVLLAMADGSAATDAALVEAIQSAHERDMTVIALTGRGGAALAGLLRETD
VLIEVPHDRAARVREVHALVLHCLCDGVDAQLFGEQEIPL
>Mature_200_residues
MLEQRIQQHFIDSADLKYQAAQLLSQPIGAAVQAILACVTSGAKVLACGSGAASAQARQFAALCVAGFERERPELAAVAL
EPDALWSAPGMPGGDAQVLARQVRALGQAGDVLLAMADGSAATDAALVEAIQSAHERDMTVIALTGRGGAALAGLLRETD
VLIEVPHDRAARVREVHALVLHCLCDGVDAQLFGEQEIPL

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=197, Percent_Identity=41.6243654822335, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786416, Length=153, Percent_Identity=33.9869281045752, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20752; Mature: 20752

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQRIQQHFIDSADLKYQAAQLLSQPIGAAVQAILACVTSGAKVLACGSGAASAQARQF
CCHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHH
AALCVAGFERERPELAAVALEPDALWSAPGMPGGDAQVLARQVRALGQAGDVLLAMADGS
HHHHHHHHCCCCCCEEEEEECCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCC
AATDAALVEAIQSAHERDMTVIALTGRGGAALAGLLRETDVLIEVPHDRAARVREVHALV
CHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHH
LHCLCDGVDAQLFGEQEIPL
HHHHHCCCCHHHCCCCCCCC
>Mature Secondary Structure
MLEQRIQQHFIDSADLKYQAAQLLSQPIGAAVQAILACVTSGAKVLACGSGAASAQARQF
CCHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHH
AALCVAGFERERPELAAVALEPDALWSAPGMPGGDAQVLARQVRALGQAGDVLLAMADGS
HHHHHHHHCCCCCCEEEEEECCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCC
AATDAALVEAIQSAHERDMTVIALTGRGGAALAGLLRETDVLIEVPHDRAARVREVHALV
CHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHH
LHCLCDGVDAQLFGEQEIPL
HHHHHCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA