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The map label for this gene is gdhA [H]

Identifier: 120609114

GI number: 120609114

Start: 442263

End: 444833

Strand: Direct

Name: gdhA [H]

Synonym: Aave_0411

Alternate gene names: 120609114

Gene position: 442263-444833 (Clockwise)

Preceding gene: 120609113

Following gene: 120609115

Centisome position: 8.26

GC content: 71.33

Gene sequence:

>2571_bases
ATGGCAGGCCTCGCACGCATTACCGGCGTTCTCGTCGGCATCACAGGCGTTCTCGTTGCAGGTGCGGGCGGATGGCTCGT
TTCGCTGGGCGGCAGCCCCTATTACCTCATCGCCGGGCTCGCGCTGCTGGCTTCGGGCGTGCTCCTCGCACGTCGCTCCG
CGGCGGGCCTCTGGGTGTACGCCGCGCTCCTGCTGGGCTCCACGGCCTGGGCGGTCTGGGAGGTGGGCGTGGACTGGTGG
CCGCTGGCCGCGCGTCTGGATGTGCTCTTCGTGCTCGGCCTCTGGCTGGCGACGCCGTGGATGCGCCGGTCCCTGCTGCG
TGGGCCCGCGCCGCTCCAGCCGGGCCTTCCCGGCGATGCACCGGCCCGGGCTTCCTCGCTGCGCATGCCGCGCATGGCGC
TGGGGCTGGCCCTTCTCCTTTCCGCCGTGCTGGCGGTGGCATCCTGGTTCACCGCGCCGCATGAGCTGGCCGGCAGGCTG
GCGGGCGAATCCGTGCCCGCCCCGGCCCAGGCCGCGCCCACGCTGCCCGACGGCGAATGGCATGCCTACGGCCGCACCGG
CCATGGCCAGCGTTTCTCTCCCCTGGCACAGATCACGCCCGACAACGCCTCGCAGCTGAAGATGGCCTGGGAGTTCCGCA
CGGGCGACGTGCGCGGCAAGGAGGGTGATCCGGAAGAGACCACCTACGAGGTCACGCCGCTGAAGATCGGCAACCGCCTG
TTCCTGTGCACGCCGCACCAGTCGGTGATCGCGCTCGACGCCACCACAGGCAGGCAGCTCTGGCGCTACGACCCGCAGAT
CGAGGGCAAGCTGGCCCTGCAGCACCTGACCTGCCGGGGGCTGTCGTACCAGCCGCCGCGCGACCCCGTCGCCGATGCGT
CGCCCGCGGCGCTCAACGCCGTGGCGGGAGCCGCTGCGGGCGGCGAGCGCACCGAGCCGGCGCCCCATGCCTCTCCCACC
ACCACGCAGCCGGCCGCACCTGCCACGCAGGCGGCGGACCAGCGCCAGCCGCCCATCGCGGCCCGCAACGGCCCCACCGA
CGCCGCCTGCCGCGCCAAGCTCTTCATGCCCACGGCCGATGGCCGCGTGATCGCGCTCAACCCCGAAAGCGGTGCCGTAT
GCACCAACTTCGGCGGCGGCACGGGCCAGATCGACCTGTGGCAGCGCATGCCCAACCTGCGCCCCGGCGCCTACTATTCG
ACGTCTCCCGTGGTGGTCACGCAGCGCCTCGTGATCGTGGGCGGCACGGTGCTGGACAACGCCTCGGTGAAGGAGCAGTC
GGGCGTGATCCGTGCCTTCGACATCGACTCCGGCGCGCTGGTGTGGAACTGGGATTCCGGCAACCCCGACGACACCGCGC
CCCTGCCGCCCGGCCGCACCTACACGCCCAATTCCCCCAACAGCTGGTCGATCTCCAGCGTCGATGAAGCACTCGGCATG
GTGTACGTGCCCATGGGCAACCAGCCACCCGACCAGTGGGGCGGCAACCGCAGCCCGGCGGTGGAGAAATATTCCTCTTC
CGTCGTCGCGCTGGACCTGGACAGCGGCAAGGTGCGCTGGCACTTCCAGACCGTGCACCATGACCTGTGGGACTACGACG
TGCCTTCGCAGCCCACGCTCATCGACCTGCAGGTGGGCGGGCAAACCGTGCCGGCGCTGGTGCAGCCCACCAAGCAGGGC
GAGCTGTTCGTGCTCGACCGGCGCACCGGCACGCCGATCCTGCCGGTGACGGAGCATCCCGCGCCGCAGGGCGCCGCGAA
GGGCGACCGCACGGCGGCCACGCAACCGAAATCCGCGCTGTCGTTCGACCCGCCGCCGCTCACGGAGCGCGACATGTGGG
GCGGCACGATGTTCGACCAGCTCGCCTGCCGCATCGCCTTCCACCGGCTGCGCTACGAAGGCCGCTTCACGCCGCCGTCG
GAGCAGGGCAGCATCATCTATCCGGGCAATTTCGGCGTCTTCAACTGGGGCGGCATCGCGGTCGATCCGCAGCGGCAGGT
GGCCTTCACCACGCCGACCTACCTCGCGTTCGTCTCCAGACTGGTGCCGCGCAAGGACGACACCAGCCTGCTCGTGCAGG
AGGGCGGGCCGCCCAAGGGCAGCCTGCCGGCGCTGAACGAGAACTTCGGCGCGCCTTTCGCCGCGTCGATGAAGCCGTTC
ACGTCGCCCATCGGCCTGCCTTGCCAGGCGCCGCCCTGGGGCTATGTGGCCGGCGTGGACCTGCGCACGGGCGAAGTCGC
CTGGAAGCACCGCAACGGCACGGTGCGGGATCTCTCGCCGCTGCCCCTGCCCTTCCGCATGGGCGTGCCGGGCATCGGCG
GGCCGATGCTCACCGGAGGCGGCGTGGCTTTCTACTCGGGCGCGCTGGACAACTACGTGCGCGCCTACGACCTGAACGAT
GGCCGCATCCTCTGGCAGGACCGCCTGCCCGCGGGCGGGCAGGCCACGCCGATGAGCTATACGGGGGAAGACGGCCGGCA
ATATGTGGTCGTCGTGGCCGGGGGGCACGGCTCCACGGGCACCAAGCCCGGCGACAGCGTGCGCGCCTACGCGCTGCCTG
CGCAGAAGTAG

Upstream 100 bases:

>100_bases
CGGGCCCGCCTAGATTCGTCCCTCCGGGCCGTTCCTTTTTTCCATCCGCTGCATTGCTGCGCCGATGGCCGGCCGGGCAT
GGACACAAGGAAAAACCACC

Downstream 100 bases:

>100_bases
GCCCGCGCCGGGGTGGCGCAGGGCGGGGCGCGCTACCATGCGCCACCCCTTCGATGCAAAGGATCGCCGCGTGACCACCG
AAGCCCTGCTGGCCTATGCC

Product: quinoprotein glucose dehydrogenase

Products: NA

Alternate protein names: GDH-A; Glucose dehydrogenase A [pyrroloquinoline-quinone]; Quinoprotein glucose DH [H]

Number of amino acids: Translated: 856; Mature: 855

Protein sequence:

>856_residues
MAGLARITGVLVGITGVLVAGAGGWLVSLGGSPYYLIAGLALLASGVLLARRSAAGLWVYAALLLGSTAWAVWEVGVDWW
PLAARLDVLFVLGLWLATPWMRRSLLRGPAPLQPGLPGDAPARASSLRMPRMALGLALLLSAVLAVASWFTAPHELAGRL
AGESVPAPAQAAPTLPDGEWHAYGRTGHGQRFSPLAQITPDNASQLKMAWEFRTGDVRGKEGDPEETTYEVTPLKIGNRL
FLCTPHQSVIALDATTGRQLWRYDPQIEGKLALQHLTCRGLSYQPPRDPVADASPAALNAVAGAAAGGERTEPAPHASPT
TTQPAAPATQAADQRQPPIAARNGPTDAACRAKLFMPTADGRVIALNPESGAVCTNFGGGTGQIDLWQRMPNLRPGAYYS
TSPVVVTQRLVIVGGTVLDNASVKEQSGVIRAFDIDSGALVWNWDSGNPDDTAPLPPGRTYTPNSPNSWSISSVDEALGM
VYVPMGNQPPDQWGGNRSPAVEKYSSSVVALDLDSGKVRWHFQTVHHDLWDYDVPSQPTLIDLQVGGQTVPALVQPTKQG
ELFVLDRRTGTPILPVTEHPAPQGAAKGDRTAATQPKSALSFDPPPLTERDMWGGTMFDQLACRIAFHRLRYEGRFTPPS
EQGSIIYPGNFGVFNWGGIAVDPQRQVAFTTPTYLAFVSRLVPRKDDTSLLVQEGGPPKGSLPALNENFGAPFAASMKPF
TSPIGLPCQAPPWGYVAGVDLRTGEVAWKHRNGTVRDLSPLPLPFRMGVPGIGGPMLTGGGVAFYSGALDNYVRAYDLND
GRILWQDRLPAGGQATPMSYTGEDGRQYVVVVAGGHGSTGTKPGDSVRAYALPAQK

Sequences:

>Translated_856_residues
MAGLARITGVLVGITGVLVAGAGGWLVSLGGSPYYLIAGLALLASGVLLARRSAAGLWVYAALLLGSTAWAVWEVGVDWW
PLAARLDVLFVLGLWLATPWMRRSLLRGPAPLQPGLPGDAPARASSLRMPRMALGLALLLSAVLAVASWFTAPHELAGRL
AGESVPAPAQAAPTLPDGEWHAYGRTGHGQRFSPLAQITPDNASQLKMAWEFRTGDVRGKEGDPEETTYEVTPLKIGNRL
FLCTPHQSVIALDATTGRQLWRYDPQIEGKLALQHLTCRGLSYQPPRDPVADASPAALNAVAGAAAGGERTEPAPHASPT
TTQPAAPATQAADQRQPPIAARNGPTDAACRAKLFMPTADGRVIALNPESGAVCTNFGGGTGQIDLWQRMPNLRPGAYYS
TSPVVVTQRLVIVGGTVLDNASVKEQSGVIRAFDIDSGALVWNWDSGNPDDTAPLPPGRTYTPNSPNSWSISSVDEALGM
VYVPMGNQPPDQWGGNRSPAVEKYSSSVVALDLDSGKVRWHFQTVHHDLWDYDVPSQPTLIDLQVGGQTVPALVQPTKQG
ELFVLDRRTGTPILPVTEHPAPQGAAKGDRTAATQPKSALSFDPPPLTERDMWGGTMFDQLACRIAFHRLRYEGRFTPPS
EQGSIIYPGNFGVFNWGGIAVDPQRQVAFTTPTYLAFVSRLVPRKDDTSLLVQEGGPPKGSLPALNENFGAPFAASMKPF
TSPIGLPCQAPPWGYVAGVDLRTGEVAWKHRNGTVRDLSPLPLPFRMGVPGIGGPMLTGGGVAFYSGALDNYVRAYDLND
GRILWQDRLPAGGQATPMSYTGEDGRQYVVVVAGGHGSTGTKPGDSVRAYALPAQK
>Mature_855_residues
AGLARITGVLVGITGVLVAGAGGWLVSLGGSPYYLIAGLALLASGVLLARRSAAGLWVYAALLLGSTAWAVWEVGVDWWP
LAARLDVLFVLGLWLATPWMRRSLLRGPAPLQPGLPGDAPARASSLRMPRMALGLALLLSAVLAVASWFTAPHELAGRLA
GESVPAPAQAAPTLPDGEWHAYGRTGHGQRFSPLAQITPDNASQLKMAWEFRTGDVRGKEGDPEETTYEVTPLKIGNRLF
LCTPHQSVIALDATTGRQLWRYDPQIEGKLALQHLTCRGLSYQPPRDPVADASPAALNAVAGAAAGGERTEPAPHASPTT
TQPAAPATQAADQRQPPIAARNGPTDAACRAKLFMPTADGRVIALNPESGAVCTNFGGGTGQIDLWQRMPNLRPGAYYST
SPVVVTQRLVIVGGTVLDNASVKEQSGVIRAFDIDSGALVWNWDSGNPDDTAPLPPGRTYTPNSPNSWSISSVDEALGMV
YVPMGNQPPDQWGGNRSPAVEKYSSSVVALDLDSGKVRWHFQTVHHDLWDYDVPSQPTLIDLQVGGQTVPALVQPTKQGE
LFVLDRRTGTPILPVTEHPAPQGAAKGDRTAATQPKSALSFDPPPLTERDMWGGTMFDQLACRIAFHRLRYEGRFTPPSE
QGSIIYPGNFGVFNWGGIAVDPQRQVAFTTPTYLAFVSRLVPRKDDTSLLVQEGGPPKGSLPALNENFGAPFAASMKPFT
SPIGLPCQAPPWGYVAGVDLRTGEVAWKHRNGTVRDLSPLPLPFRMGVPGIGGPMLTGGGVAFYSGALDNYVRAYDLNDG
RILWQDRLPAGGQATPMSYTGEDGRQYVVVVAGGHGSTGTKPGDSVRAYALPAQK

Specific function: Catalyzes an exceptionally high rate of oxidation of a wide range of aldose sugars, including D-glucose, galactose, arabinose and xylose, and also the disaccharides lactose, cellobiose and maltose [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=855, Percent_Identity=45.2631578947368, Blast_Score=709, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017511
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.99.35 [H]

Molecular weight: Translated: 90964; Mature: 90833

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS00334 MYB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLARITGVLVGITGVLVAGAGGWLVSLGGSPYYLIAGLALLASGVLLARRSAAGLWVY
CCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCHHEEHHCCCHHHHH
AALLLGSTAWAVWEVGVDWWPLAARLDVLFVLGLWLATPWMRRSLLRGPAPLQPGLPGDA
HHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCC
PARASSLRMPRMALGLALLLSAVLAVASWFTAPHELAGRLAGESVPAPAQAAPTLPDGEW
CCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCE
HAYGRTGHGQRFSPLAQITPDNASQLKMAWEFRTGDVRGKEGDPEETTYEVTPLKIGNRL
EECCCCCCCCCCCCCEEECCCCHHHEEEEEEEECCCCCCCCCCCCCCEEEEEEEEECCEE
FLCTPHQSVIALDATTGRQLWRYDPQIEGKLALQHLTCRGLSYQPPRDPVADASPAALNA
EEECCCCCEEEEECCCCCHHEECCCCCCCEEEEEEHEECCCCCCCCCCCCCCCCCHHHHH
VAGAAAGGERTEPAPHASPTTTQPAAPATQAADQRQPPIAARNGPTDAACRAKLFMPTAD
HHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHEEEEEEECCC
GRVIALNPESGAVCTNFGGGTGQIDLWQRMPNLRPGAYYSTSPVVVTQRLVIVGGTVLDN
CEEEEECCCCCCEEECCCCCCCCCHHHHHCCCCCCCCEECCCCEEEEEEEEEECCEEECC
ASVKEQSGVIRAFDIDSGALVWNWDSGNPDDTAPLPPGRTYTPNSPNSWSISSVDEALGM
CCCHHHCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCE
VYVPMGNQPPDQWGGNRSPAVEKYSSSVVALDLDSGKVRWHFQTVHHDLWDYDVPSQPTL
EEEECCCCCHHHCCCCCCCHHHHHCCCEEEEECCCCEEEEEEEEEHHHHCCCCCCCCCEE
IDLQVGGQTVPALVQPTKQGELFVLDRRTGTPILPVTEHPAPQGAAKGDRTAATQPKSAL
EEEEECCCCCCHHCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
SFDPPPLTERDMWGGTMFDQLACRIAFHRLRYEGRFTPPSEQGSIIYPGNFGVFNWGGIA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCEEECCCEE
VDPQRQVAFTTPTYLAFVSRLVPRKDDTSLLVQEGGPPKGSLPALNENFGAPFAASMKPF
ECCCCCEEEECHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
TSPIGLPCQAPPWGYVAGVDLRTGEVAWKHRNGTVRDLSPLPLPFRMGVPGIGGPMLTGG
CCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEECCC
GVAFYSGALDNYVRAYDLNDGRILWQDRLPAGGQATPMSYTGEDGRQYVVVVAGGHGSTG
CCEEECCHHHCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCC
TKPGDSVRAYALPAQK
CCCCCCEEEEECCCCC
>Mature Secondary Structure 
AGLARITGVLVGITGVLVAGAGGWLVSLGGSPYYLIAGLALLASGVLLARRSAAGLWVY
CCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCHHEEHHCCCHHHHH
AALLLGSTAWAVWEVGVDWWPLAARLDVLFVLGLWLATPWMRRSLLRGPAPLQPGLPGDA
HHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCC
PARASSLRMPRMALGLALLLSAVLAVASWFTAPHELAGRLAGESVPAPAQAAPTLPDGEW
CCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCE
HAYGRTGHGQRFSPLAQITPDNASQLKMAWEFRTGDVRGKEGDPEETTYEVTPLKIGNRL
EECCCCCCCCCCCCCEEECCCCHHHEEEEEEEECCCCCCCCCCCCCCEEEEEEEEECCEE
FLCTPHQSVIALDATTGRQLWRYDPQIEGKLALQHLTCRGLSYQPPRDPVADASPAALNA
EEECCCCCEEEEECCCCCHHEECCCCCCCEEEEEEHEECCCCCCCCCCCCCCCCCHHHHH
VAGAAAGGERTEPAPHASPTTTQPAAPATQAADQRQPPIAARNGPTDAACRAKLFMPTAD
HHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHEEEEEEECCC
GRVIALNPESGAVCTNFGGGTGQIDLWQRMPNLRPGAYYSTSPVVVTQRLVIVGGTVLDN
CEEEEECCCCCCEEECCCCCCCCCHHHHHCCCCCCCCEECCCCEEEEEEEEEECCEEECC
ASVKEQSGVIRAFDIDSGALVWNWDSGNPDDTAPLPPGRTYTPNSPNSWSISSVDEALGM
CCCHHHCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCE
VYVPMGNQPPDQWGGNRSPAVEKYSSSVVALDLDSGKVRWHFQTVHHDLWDYDVPSQPTL
EEEECCCCCHHHCCCCCCCHHHHHCCCEEEEECCCCEEEEEEEEEHHHHCCCCCCCCCEE
IDLQVGGQTVPALVQPTKQGELFVLDRRTGTPILPVTEHPAPQGAAKGDRTAATQPKSAL
EEEEECCCCCCHHCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
SFDPPPLTERDMWGGTMFDQLACRIAFHRLRYEGRFTPPSEQGSIIYPGNFGVFNWGGIA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCEEECCCEE
VDPQRQVAFTTPTYLAFVSRLVPRKDDTSLLVQEGGPPKGSLPALNENFGAPFAASMKPF
ECCCCCEEEECHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
TSPIGLPCQAPPWGYVAGVDLRTGEVAWKHRNGTVRDLSPLPLPFRMGVPGIGGPMLTGG
CCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEECCC
GVAFYSGALDNYVRAYDLNDGRILWQDRLPAGGQATPMSYTGEDGRQYVVVVAGGHGSTG
CCEEECCHHHCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCC
TKPGDSVRAYALPAQK
CCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3399393 [H]