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The map label for this gene is bepR [H]

Identifier: 120609093

GI number: 120609093

Start: 420283

End: 420975

Strand: Direct

Name: bepR [H]

Synonym: Aave_0390

Alternate gene names: 120609093

Gene position: 420283-420975 (Clockwise)

Preceding gene: 120609087

Following gene: 120609094

Centisome position: 7.85

GC content: 66.38

Gene sequence:

>693_bases
ATGGCCCGACGTACCAAGGAAGATGCGGTCGCCACCCGCAACAGCCTGTTGGATGCTGCAGAACACGTTTTCTATCAGAA
GGGGGTTTCAAACGCCTCCCTGAACGACATCGCCCAGGCCGCCGGCGCCACGCGCGGCGCCATCTATTGGCATTTCAAGG
ACAAGGTGGACCTGTTCAACGCCATGATGGAGCGTGTGACGCTGCCGCTGGAGTGCGCGAGCGACGAGTGCGCGGGGCAC
AACCGCATGTCCCCGCTGCATCGCCTGCGGGCCGTGATCGATTTCGTGCTGCGCAGTCTGGAGAAAGACGAATCCGTGCG
CCGTGTGTTCGAGATCGCGATGTTCCGCGTGGAGTACGTGGGCGAGCTGTCCGTCGTGCGGGACCGCCATGTCGAGGCCA
GCCTGGAGTTCCGCCGGCAGTTCGCCGCCGAACTGGCCCTCGCGGCGAACGACCAGGGCGTGGAACTGCCGTCCTCGGCG
GACGTGGCGGCCGTAGGGCTGCAGGCGCTGTTCGATGGCCTGATGCAGGTCTGGATGCTGGGAGGCGCGACCTTCGGCCT
GGCGGAGACCGGCCGCGCGACCGTGGATGCCTACCTGCGCGGCCTGGGCTTCGACGTGTCGGCCGGTTTCGATCCGCTTT
CCGCGGGCATCCCCTGGAAGATTTGCCAGCCGCGCCGCAACGCCGTGCCATAA

Upstream 100 bases:

>100_bases
CATACAAACATGAATGTATAATTGTGGAATGCCGGGTGCGGAGGCGCGGCCGCAATGCCTGCCTGCCGCCCGGCCCCTGC
AGATCAAGGAGACACCCCAC

Downstream 100 bases:

>100_bases
TCCCGGTCCGGGCCGCAAGGGCCCGCATGCGGCTGTAGCTCAGTGGATAGAGTATTGGCCTCCGAAGCCAAGGGTCGTGG
GTTCGATCCCCGCCAGCCGC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MARRTKEDAVATRNSLLDAAEHVFYQKGVSNASLNDIAQAAGATRGAIYWHFKDKVDLFNAMMERVTLPLECASDECAGH
NRMSPLHRLRAVIDFVLRSLEKDESVRRVFEIAMFRVEYVGELSVVRDRHVEASLEFRRQFAAELALAANDQGVELPSSA
DVAAVGLQALFDGLMQVWMLGGATFGLAETGRATVDAYLRGLGFDVSAGFDPLSAGIPWKICQPRRNAVP

Sequences:

>Translated_230_residues
MARRTKEDAVATRNSLLDAAEHVFYQKGVSNASLNDIAQAAGATRGAIYWHFKDKVDLFNAMMERVTLPLECASDECAGH
NRMSPLHRLRAVIDFVLRSLEKDESVRRVFEIAMFRVEYVGELSVVRDRHVEASLEFRRQFAAELALAANDQGVELPSSA
DVAAVGLQALFDGLMQVWMLGGATFGLAETGRATVDAYLRGLGFDVSAGFDPLSAGIPWKICQPRRNAVP
>Mature_229_residues
ARRTKEDAVATRNSLLDAAEHVFYQKGVSNASLNDIAQAAGATRGAIYWHFKDKVDLFNAMMERVTLPLECASDECAGHN
RMSPLHRLRAVIDFVLRSLEKDESVRRVFEIAMFRVEYVGELSVVRDRHVEASLEFRRQFAAELALAANDQGVELPSSAD
VAAVGLQALFDGLMQVWMLGGATFGLAETGRATVDAYLRGLGFDVSAGFDPLSAGIPWKICQPRRNAVP

Specific function: Represses expression of bepDE [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786669, Length=195, Percent_Identity=35.8974358974359, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1789664, Length=204, Percent_Identity=32.843137254902, Blast_Score=100, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR013572
- InterPro:   IPR001647 [H]

Pfam domain/function: PF08361 TetR_C_2; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 25302; Mature: 25171

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRTKEDAVATRNSLLDAAEHVFYQKGVSNASLNDIAQAAGATRGAIYWHFKDKVDLFN
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEECHHHHHHH
AMMERVTLPLECASDECAGHNRMSPLHRLRAVIDFVLRSLEKDESVRRVFEIAMFRVEYV
HHHHHHCCCHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GELSVVRDRHVEASLEFRRQFAAELALAANDQGVELPSSADVAAVGLQALFDGLMQVWML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GGATFGLAETGRATVDAYLRGLGFDVSAGFDPLSAGIPWKICQPRRNAVP
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARRTKEDAVATRNSLLDAAEHVFYQKGVSNASLNDIAQAAGATRGAIYWHFKDKVDLFN
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEECHHHHHHH
AMMERVTLPLECASDECAGHNRMSPLHRLRAVIDFVLRSLEKDESVRRVFEIAMFRVEYV
HHHHHHCCCHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GELSVVRDRHVEASLEFRRQFAAELALAANDQGVELPSSADVAAVGLQALFDGLMQVWML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GGATFGLAETGRATVDAYLRGLGFDVSAGFDPLSAGIPWKICQPRRNAVP
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]