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The map label for this gene is feaR [H]

Identifier: 120608858

GI number: 120608858

Start: 164925

End: 165863

Strand: Direct

Name: feaR [H]

Synonym: Aave_0150

Alternate gene names: 120608858

Gene position: 164925-165863 (Clockwise)

Preceding gene: 120608857

Following gene: 120608861

Centisome position: 3.08

GC content: 74.87

Gene sequence:

>939_bases
ATGCACGACGGCCTTCGCACCTGGACCACCGACGCCGTTCCCCCCGCGCAGCGGGCCGACTACTGGGTCGGCGCCGTCTG
CGACTGCTTCCTCGACATGGAGGTCGAGCCGGGCCAGCGCCACGCGTTCTCGGCCACGCTCACGTCCGTGCCCTGCGGCG
GCCTGCGCGTCAACCGCGTGAGCGGCAGCGGGCAGCGCGTGCGCCGCACGCAGCAGGCCATCCGCCGCGGGGACGGCGAC
AACTTCTACTACCTGCTCTGCAAGGACTCCGCCCCCTGCCACGTCGCGCAGGACGGTGCCGGTGCCGCGCGCCTGCTGCC
CGGCGACCTGGCCCTGGTCGATTCGCGCCGCCGCTACCTGCTGGACTTTCCGGACGTGGTGGACACCGTCTCCATCCAGA
TCCCGATCGGCTGGCTGGACACCTGGCTGCCCGCCGCCGACCGCTGGCTGGGCCGCCGCGTGGACGGCGCCACGGGCTGG
GGGAGGGTGCTGAGCGCCTACGTGGGCCAGCTGTGCGCCGAGCGGCCGGAACGGCTGGCCGCGCTGCAGGCCGAGCACCT
GGGCGGCCTGCTGTCCCTGGCCTGCGGCCCCGTGCCCGAGGCGCCGCCGCGCACCGGCCTGCTGCCGCGCATCGAACAGT
GCGTGCGCGAGCGCTTCTGCGAGCCCGGGCTCACCGCCGCCCACGTGGCCGATGATGTCGGCGTGTCGCTGCGCACGCTG
CACCGCGTGCTGTCGTCGGGTGGCACCACCTTCGCGGTACTGCTCATGCGCGAGCGCATGGCCGTGGCGCAGCGCATGCT
GCACGCACCCTCGCACCGGCATGTGACGGTGGCCGAGATCGGACGGCGCGCGGGCTTCCTGGACCCGTCGCACTTCGCGC
GCGCCTGCCGGCAGTGGTGCGGCAGGACGCCCGCGCAGGAGCGCGCCCGGGCTGCGTGA

Upstream 100 bases:

>100_bases
CGTCGTCCATCATCCTGGTGGCCGCCGTGCCGGCGGTGCTCGCAGCCGTGGCGGTGGTGCTGCTCGGGCAGGCGCGGCGC
GGCGCCTGAGAAGGCATGCC

Downstream 100 bases:

>100_bases
ATGGAAGAGGCGATGCCTTGCGGGCCGTGAACGTCACCAGGGCCAGGCCACCGGCAGCCCGAGCCCGGCGGCACCCGCCT
GCTCCTGCACCAGCCGGGCC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MHDGLRTWTTDAVPPAQRADYWVGAVCDCFLDMEVEPGQRHAFSATLTSVPCGGLRVNRVSGSGQRVRRTQQAIRRGDGD
NFYYLLCKDSAPCHVAQDGAGAARLLPGDLALVDSRRRYLLDFPDVVDTVSIQIPIGWLDTWLPAADRWLGRRVDGATGW
GRVLSAYVGQLCAERPERLAALQAEHLGGLLSLACGPVPEAPPRTGLLPRIEQCVRERFCEPGLTAAHVADDVGVSLRTL
HRVLSSGGTTFAVLLMRERMAVAQRMLHAPSHRHVTVAEIGRRAGFLDPSHFARACRQWCGRTPAQERARAA

Sequences:

>Translated_312_residues
MHDGLRTWTTDAVPPAQRADYWVGAVCDCFLDMEVEPGQRHAFSATLTSVPCGGLRVNRVSGSGQRVRRTQQAIRRGDGD
NFYYLLCKDSAPCHVAQDGAGAARLLPGDLALVDSRRRYLLDFPDVVDTVSIQIPIGWLDTWLPAADRWLGRRVDGATGW
GRVLSAYVGQLCAERPERLAALQAEHLGGLLSLACGPVPEAPPRTGLLPRIEQCVRERFCEPGLTAAHVADDVGVSLRTL
HRVLSSGGTTFAVLLMRERMAVAQRMLHAPSHRHVTVAEIGRRAGFLDPSHFARACRQWCGRTPAQERARAA
>Mature_312_residues
MHDGLRTWTTDAVPPAQRADYWVGAVCDCFLDMEVEPGQRHAFSATLTSVPCGGLRVNRVSGSGQRVRRTQQAIRRGDGD
NFYYLLCKDSAPCHVAQDGAGAARLLPGDLALVDSRRRYLLDFPDVVDTVSIQIPIGWLDTWLPAADRWLGRRVDGATGW
GRVLSAYVGQLCAERPERLAALQAEHLGGLLSLACGPVPEAPPRTGLLPRIEQCVRERFCEPGLTAAHVADDVGVSLRTL
HRVLSSGGTTFAVLLMRERMAVAQRMLHAPSHRHVTVAEIGRRAGFLDPSHFARACRQWCGRTPAQERARAA

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=280, Percent_Identity=23.9285714285714, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34157; Mature: 34157

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDGLRTWTTDAVPPAQRADYWVGAVCDCFLDMEVEPGQRHAFSATLTSVPCGGLRVNRV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCEEEEEE
SGSGQRVRRTQQAIRRGDGDNFYYLLCKDSAPCHVAQDGAGAARLLPGDLALVDSRRRYL
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCCCEEECCCCHHHHCCCCHHC
LDFPDVVDTVSIQIPIGWLDTWLPAADRWLGRRVDGATGWGRVLSAYVGQLCAERPERLA
CCCCHHHCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALQAEHLGGLLSLACGPVPEAPPRTGLLPRIEQCVRERFCEPGLTAAHVADDVGVSLRTL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHH
HRVLSSGGTTFAVLLMRERMAVAQRMLHAPSHRHVTVAEIGRRAGFLDPSHFARACRQWC
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCHHHHHHHHHHHH
GRTPAQERARAA
CCCCHHHHHCCC
>Mature Secondary Structure
MHDGLRTWTTDAVPPAQRADYWVGAVCDCFLDMEVEPGQRHAFSATLTSVPCGGLRVNRV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCEEEEEE
SGSGQRVRRTQQAIRRGDGDNFYYLLCKDSAPCHVAQDGAGAARLLPGDLALVDSRRRYL
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCCCEEECCCCHHHHCCCCHHC
LDFPDVVDTVSIQIPIGWLDTWLPAADRWLGRRVDGATGWGRVLSAYVGQLCAERPERLA
CCCCHHHCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALQAEHLGGLLSLACGPVPEAPPRTGLLPRIEQCVRERFCEPGLTAAHVADDVGVSLRTL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHH
HRVLSSGGTTFAVLLMRERMAVAQRMLHAPSHRHVTVAEIGRRAGFLDPSHFARACRQWC
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCHHHHHHHHHHHH
GRTPAQERARAA
CCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]