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The map label for this gene is cbiL [H]

Identifier: 120608783

GI number: 120608783

Start: 81453

End: 82352

Strand: Direct

Name: cbiL [H]

Synonym: Aave_0073

Alternate gene names: 120608783

Gene position: 81453-82352 (Clockwise)

Preceding gene: 120608782

Following gene: 120608784

Centisome position: 1.52

GC content: 71.0

Gene sequence:

>900_bases
ATGACCGCCGAGCACACCACCATCACGAGCGCGCCGCGGCCGCAGGACACGCACACTCCGCCGACGCGGGGCCCGCTGGG
CCGCCTCATCGGCGTTTCGCTCGGCCCGGGCGACCCCGGCCTCATCACCCGCGCCGCCTGGGCGCAACTGCAGCGCACCG
ACGCCGTGTGGACCTATCCCGCGCGCAGCACCAAAACGCCCAGCTACGCGTTCGACATCGTGCAGCGCGCCGGCCTCGCG
CCGCCCGCCACGCACCAGACGCTGCTTTTCCCGATGACGCACGACGGCGACAAGCTCGCCCGTGCCTGGATGCGCGCCGC
GGACACCGTGCTGCCCTGGCTGCAGGCCGGGCAGGACGTGCTTTTCCTGGTCGAGGGCGACGCCAGCACCTACGCCACCT
TCGGCCACCTGGCGCGCACCGTGCGGGCGCTGGATGCGCGCATCGAAGTGCCGGTGATCGCGGGCGTCAACGCCTTCACG
GCCGCCTGCGCCACGCGCGGCATGCCGCTGGCCGAGCAGGACGACACCATCGCCATCGTGCCCGCCGCCTATGGCGTGAG
CGCGGTGGATCGCCTGCTGCCCGACTTCGACACCCTGGTGCTGATGAAGGTCAAGCCCCTCATGGACGACCTGATCGACT
GGCTGGAGCGGCGCGGCCTGCTGCCCAACACCCAGTTCATCGAGCGCGTGGGCGCACCCGACGAGCGCTGCGTGGCCGGC
ACCGATCTGCCCGCGCTGCGCGGCACCAAGGTCAGCTACCTCTCGCTCATGGTGGTGAAGAACCCGCACCGCATCCGCGG
CGAGCGCATCAAGGGCTGCCTGAAGAAGACATTGCCCGCGGCCTCCACGGCTTCCGTGGTGGACCAACCCCTTTCCGACG
AACCGGAGCTTGCCGAATGA

Upstream 100 bases:

>100_bases
TCCTGCACATGCACCGCATGGCGGCCGAGAACCCGGTGTGGATCGTCTGCGCGCAGGCGGGCAGCGTCGGGACTGCTGCC
GTCGCCGTGGAGGAGGGCGC

Downstream 100 bases:

>100_bases
ATACCCCTGCCACCCCTGACGTGGTGCTCTCCGCCCCCGCGCAGCCCGCCGGCGAGGTGCGCGTGTGCCTCGTCGCCATC
ACCCGCCACGGCGCCGCCCA

Product: cobalt-factor II C20-methyltransferase / precorrin-2 C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTAEHTTITSAPRPQDTHTPPTRGPLGRLIGVSLGPGDPGLITRAAWAQLQRTDAVWTYPARSTKTPSYAFDIVQRAGLA
PPATHQTLLFPMTHDGDKLARAWMRAADTVLPWLQAGQDVLFLVEGDASTYATFGHLARTVRALDARIEVPVIAGVNAFT
AACATRGMPLAEQDDTIAIVPAAYGVSAVDRLLPDFDTLVLMKVKPLMDDLIDWLERRGLLPNTQFIERVGAPDERCVAG
TDLPALRGTKVSYLSLMVVKNPHRIRGERIKGCLKKTLPAASTASVVDQPLSDEPELAE

Sequences:

>Translated_299_residues
MTAEHTTITSAPRPQDTHTPPTRGPLGRLIGVSLGPGDPGLITRAAWAQLQRTDAVWTYPARSTKTPSYAFDIVQRAGLA
PPATHQTLLFPMTHDGDKLARAWMRAADTVLPWLQAGQDVLFLVEGDASTYATFGHLARTVRALDARIEVPVIAGVNAFT
AACATRGMPLAEQDDTIAIVPAAYGVSAVDRLLPDFDTLVLMKVKPLMDDLIDWLERRGLLPNTQFIERVGAPDERCVAG
TDLPALRGTKVSYLSLMVVKNPHRIRGERIKGCLKKTLPAASTASVVDQPLSDEPELAE
>Mature_298_residues
TAEHTTITSAPRPQDTHTPPTRGPLGRLIGVSLGPGDPGLITRAAWAQLQRTDAVWTYPARSTKTPSYAFDIVQRAGLAP
PATHQTLLFPMTHDGDKLARAWMRAADTVLPWLQAGQDVLFLVEGDASTYATFGHLARTVRALDARIEVPVIAGVNAFTA
ACATRGMPLAEQDDTIAIVPAAYGVSAVDRLLPDFDTLVLMKVKPLMDDLIDWLERRGLLPNTQFIERVGAPDERCVAGT
DLPALRGTKVSYLSLMVVKNPHRIRGERIKGCLKKTLPAASTASVVDQPLSDEPELAE

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 32344; Mature: 32212

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAEHTTITSAPRPQDTHTPPTRGPLGRLIGVSLGPGDPGLITRAAWAQLQRTDAVWTYP
CCCCCCEECCCCCCCCCCCCCCCCCCHHHEEEECCCCCCCHHHHHHHHHHHHCCCEEECC
ARSTKTPSYAFDIVQRAGLAPPATHQTLLFPMTHDGDKLARAWMRAADTVLPWLQAGQDV
CCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCE
LFLVEGDASTYATFGHLARTVRALDARIEVPVIAGVNAFTAACATRGMPLAEQDDTIAIV
EEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCCCCCCCCEEEEE
PAAYGVSAVDRLLPDFDTLVLMKVKPLMDDLIDWLERRGLLPNTQFIERVGAPDERCVAG
ECHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEECC
TDLPALRGTKVSYLSLMVVKNPHRIRGERIKGCLKKTLPAASTASVVDQPLSDEPELAE
CCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TAEHTTITSAPRPQDTHTPPTRGPLGRLIGVSLGPGDPGLITRAAWAQLQRTDAVWTYP
CCCCCEECCCCCCCCCCCCCCCCCCHHHEEEECCCCCCCHHHHHHHHHHHHCCCEEECC
ARSTKTPSYAFDIVQRAGLAPPATHQTLLFPMTHDGDKLARAWMRAADTVLPWLQAGQDV
CCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCE
LFLVEGDASTYATFGHLARTVRALDARIEVPVIAGVNAFTAACATRGMPLAEQDDTIAIV
EEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCCCCCCCCEEEEE
PAAYGVSAVDRLLPDFDTLVLMKVKPLMDDLIDWLERRGLLPNTQFIERVGAPDERCVAG
ECHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEECC
TDLPALRGTKVSYLSLMVVKNPHRIRGERIKGCLKKTLPAASTASVVDQPLSDEPELAE
CCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]