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The map label for this gene is aroG [H]

Identifier: 120608734

GI number: 120608734

Start: 21747

End: 22889

Strand: Direct

Name: aroG [H]

Synonym: Aave_0021

Alternate gene names: 120608734

Gene position: 21747-22889 (Clockwise)

Preceding gene: 120608733

Following gene: 120608735

Centisome position: 0.41

GC content: 69.73

Gene sequence:

>1143_bases
ATGAACCGCACCATTTCCCAGGACGCCGGCGGCGTCGCCTCCGCTTCGCACGTCCACCGCGCCACGCCGCAGTCCGGCAC
GCACGACACCACCCGCATCGACGACACGCGCATCAAGGCGGTGCGGCCGCTGATCACGCCCGCGCTGCTGCAGGAGTGGC
TGCCCGCCTCGGACGACGCCCGGGCCCTGGTGGAATCCAGCCGCGCCGCGCTTTCGCGGGTGCTGCACGGCGAGGACGAC
CGGCTCATCGTGGTGGTGGGGCCGTGCTCCATCCACGACCATGGCCAGGCCATGGAGTACGCGAAGGCGCTCAAGGCGCA
GGCCGACCGGCTGTCCGCGGAACTGCTGGTGGTCATGCGCGTGTATTTCGAGAAACCCCGCACCACGGTGGGCTGGAAGG
GTTACATCAATGACCCGCACCTGGACGGCAGCTTCGCGATCAACGAAGGCCTGGAGATGGCGCGCAAGCTGCTGCTGGAC
GTGCTGGCGCTCGGCCTGCCCGTGGGAACGGAATTCCTGGACCTGCTCTCGCCGCAATTCATCAGCGACCTGGTGAGCTG
GGGTGCGATCGGCGCGCGCACCACCGAGAGCCAAAGCCACCGCCAGCTGGCCAGCGGCCTGTCCTGCCCCGTGGGCTTCA
AGAACGGCACCGATGGCGGTGTGAAGGTGGCCTCCGACGCCATCCTCGCCGCACAGGCGCCGCATGCCTTCATGGGCATG
ACCAAGATGGGCCAGGCCGCCATTTTCGAGACGCGCGGCAATCGCGACTGCCACGTGATCCTGCGCGGCGGCCGCCAACC
GAACTACGGGGCGGCCGACGTGGACGCGGCCTGCGGCCTGCTGCGCGGCACGGGACTGCGCGAGCAGGTGATGATCGATG
TCTCCCATGCCAACAGCAGCAAGCAGCACCGCCGCCAGATCGAGGTGGCGGCCGACGTGGCGGCGCAGGTCGCCGCCGGC
GACGGCCGCATCACCGGCGTGATGATCGAAAGCCATCTGCGGGAAGGCCGCCAGGACATCGTGCCCGGGCAACCCCTGCA
GTCCGGCGTGTCGGTGACGGACGCCTGTATCGGCTTCGACCAGACGGTGCCGGTGCTCGAGGGACTCGCAGCCGCCGTTC
GGTCGCGCCGCAGCCACCGCTGA

Upstream 100 bases:

>100_bases
TCGCGTTCCGCAGGCCGTGAGGCCTGCGCCGGACGGCGCGGACCGTCCGGTGCGATCTGGAACAAGGCGCGTTTTCGCGG
GCGCGCGACAATTGCAGCCC

Downstream 100 bases:

>100_bases
TCCGCGGCTGTTGTTTTCTGCACGGATCGGCCGCCCCTGTCCGTCATTCAGACGGTTGGCAGGGTGTAGCATTCGGAAAC
ATGCAGGCCGGATCGTCTGC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MNRTISQDAGGVASASHVHRATPQSGTHDTTRIDDTRIKAVRPLITPALLQEWLPASDDARALVESSRAALSRVLHGEDD
RLIVVVGPCSIHDHGQAMEYAKALKAQADRLSAELLVVMRVYFEKPRTTVGWKGYINDPHLDGSFAINEGLEMARKLLLD
VLALGLPVGTEFLDLLSPQFISDLVSWGAIGARTTESQSHRQLASGLSCPVGFKNGTDGGVKVASDAILAAQAPHAFMGM
TKMGQAAIFETRGNRDCHVILRGGRQPNYGAADVDAACGLLRGTGLREQVMIDVSHANSSKQHRRQIEVAADVAAQVAAG
DGRITGVMIESHLREGRQDIVPGQPLQSGVSVTDACIGFDQTVPVLEGLAAAVRSRRSHR

Sequences:

>Translated_380_residues
MNRTISQDAGGVASASHVHRATPQSGTHDTTRIDDTRIKAVRPLITPALLQEWLPASDDARALVESSRAALSRVLHGEDD
RLIVVVGPCSIHDHGQAMEYAKALKAQADRLSAELLVVMRVYFEKPRTTVGWKGYINDPHLDGSFAINEGLEMARKLLLD
VLALGLPVGTEFLDLLSPQFISDLVSWGAIGARTTESQSHRQLASGLSCPVGFKNGTDGGVKVASDAILAAQAPHAFMGM
TKMGQAAIFETRGNRDCHVILRGGRQPNYGAADVDAACGLLRGTGLREQVMIDVSHANSSKQHRRQIEVAADVAAQVAAG
DGRITGVMIESHLREGRQDIVPGQPLQSGVSVTDACIGFDQTVPVLEGLAAAVRSRRSHR
>Mature_380_residues
MNRTISQDAGGVASASHVHRATPQSGTHDTTRIDDTRIKAVRPLITPALLQEWLPASDDARALVESSRAALSRVLHGEDD
RLIVVVGPCSIHDHGQAMEYAKALKAQADRLSAELLVVMRVYFEKPRTTVGWKGYINDPHLDGSFAINEGLEMARKLLLD
VLALGLPVGTEFLDLLSPQFISDLVSWGAIGARTTESQSHRQLASGLSCPVGFKNGTDGGVKVASDAILAAQAPHAFMGM
TKMGQAAIFETRGNRDCHVILRGGRQPNYGAADVDAACGLLRGTGLREQVMIDVSHANSSKQHRRQIEVAADVAAQVAAG
DGRITGVMIESHLREGRQDIVPGQPLQSGVSVTDACIGFDQTVPVLEGLAAAVRSRRSHR

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=344, Percent_Identity=59.5930232558139, Blast_Score=423, Evalue=1e-120,
Organism=Escherichia coli, GI1787996, Length=346, Percent_Identity=52.8901734104046, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1788953, Length=335, Percent_Identity=52.5373134328358, Blast_Score=355, Evalue=4e-99,
Organism=Saccharomyces cerevisiae, GI6319726, Length=349, Percent_Identity=53.2951289398281, Blast_Score=350, Evalue=3e-97,
Organism=Saccharomyces cerevisiae, GI6320240, Length=358, Percent_Identity=48.6033519553073, Blast_Score=338, Evalue=7e-94,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 40618; Mature: 40618

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTISQDAGGVASASHVHRATPQSGTHDTTRIDDTRIKAVRPLITPALLQEWLPASDDA
CCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
RALVESSRAALSRVLHGEDDRLIVVVGPCSIHDHGQAMEYAKALKAQADRLSAELLVVMR
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VYFEKPRTTVGWKGYINDPHLDGSFAINEGLEMARKLLLDVLALGLPVGTEFLDLLSPQF
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHH
ISDLVSWGAIGARTTESQSHRQLASGLSCPVGFKNGTDGGVKVASDAILAAQAPHAFMGM
HHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEECCCHHHHHCCCHHHHHH
TKMGQAAIFETRGNRDCHVILRGGRQPNYGAADVDAACGLLRGTGLREQVMIDVSHANSS
HHCCCEEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCC
KQHRRQIEVAADVAAQVAAGDGRITGVMIESHLREGRQDIVPGQPLQSGVSVTDACIGFD
HHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCHHHCCCCCCHHHCCCHHHHHHCCC
QTVPVLEGLAAAVRSRRSHR
CHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNRTISQDAGGVASASHVHRATPQSGTHDTTRIDDTRIKAVRPLITPALLQEWLPASDDA
CCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
RALVESSRAALSRVLHGEDDRLIVVVGPCSIHDHGQAMEYAKALKAQADRLSAELLVVMR
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VYFEKPRTTVGWKGYINDPHLDGSFAINEGLEMARKLLLDVLALGLPVGTEFLDLLSPQF
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHH
ISDLVSWGAIGARTTESQSHRQLASGLSCPVGFKNGTDGGVKVASDAILAAQAPHAFMGM
HHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEECCCHHHHHCCCHHHHHH
TKMGQAAIFETRGNRDCHVILRGGRQPNYGAADVDAACGLLRGTGLREQVMIDVSHANSS
HHCCCEEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCC
KQHRRQIEVAADVAAQVAAGDGRITGVMIESHLREGRQDIVPGQPLQSGVSVTDACIGFD
HHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCHHHCCCCCCHHHCCCHHHHHHCCC
QTVPVLEGLAAAVRSRRSHR
CHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]