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The map label for this gene is recG [H]

Identifier: 119947094

GI number: 119947094

Start: 4321316

End: 4323388

Strand: Reverse

Name: recG [H]

Synonym: Ping_3492

Alternate gene names: 119947094

Gene position: 4323388-4321316 (Counterclockwise)

Preceding gene: 119947096

Following gene: 119947093

Centisome position: 94.82

GC content: 45.49

Gene sequence:

>2073_bases
ATGAAATTAGATAAAATGCCCTTAACGGCGCTTAAAGGGGTCGGCATTAAAGCCTCGCAAAGGCTGGCTAAGATTGGTCT
GCACAGTGTTGCTGATTTGCTCTTTCATCTGCCTTTGCATTATCAAGATAGAACCCGAATTTATGCCATCGCAGATTTAA
AAGACAGTATGCAGGTCAGTGTGCAGGGCAAAGTATTAAGCTGCGATCTACAGTCCGGCAAGAGACGCATTCTAAAATGT
AAAATAAGCGACGGCAGTGGTAGCGTAACCCTTAACTTCTTCCATTTTAATACAGCACAGCAAAATAGCTTTGTAAAAGG
GGCATTAATCAAATGTTTTGGTGAGTTTCGTCGCGGTTACCACGGGTTTGAAGTTACTCATCCCGATTACCGCCTGCTTA
ATGCAATGCAGCAAAGCCATGTTGAGGAGACGTTAACGCCGATCTACCCGTCAACAGAAGGTTTAAAACAAAACAGTCTG
CGTAGTTTAACCGAGCAAGCGTTACTTCACCTAGAGCAACATCAGATTGATGAATTATTGCCAACTCATCTGCTGGCTCA
CCCGATCAGTTTATCAGATGCACTTTTTTATATACATCGCCCGCCACCCGATGCCAGCATCGAACAATTAGAAAACAAAA
CCCACCCTGCGCAGCAACGTTTAATTATTGAAGAATTATCAGCACAACAAATCAGTATGCTGTCTTTACGGGTAAATGCA
CAGCAACATCAAGCCATTGCGGTCAAAGAAAGCGGTTTACTGCAGGATAGGTTATTACAAAGTCTGCCTTTTTCTCTCAC
TAATGCACAACATAGAGTGAACTGGGAGATTCAACAGGATCTAAAGCAAACAATACCGATGATGCGTTTGGTGCAGGGGG
ATGTCGGATCCGGGAAAACCTTAGTGGCAGCGATCGCGGCATTAAGTGTTATTGAGGCAGGTTATCAGGTGGCATTAATG
GCCCCCACTGAACTTTTAGCAGAGCAGCATCTGCTTAATTTTCAAAAATGGTTTGCCGCACTTGATGTGTCTGTCGGTAT
GCTTTCTGGAAAAATGCGCGTCAAAGAAAAGCGTTCTCAGTTAGAAAATATCAGCTTGGGTTTATCGAAGATGGTGGTAG
GGACGCATGCGCTGTTTCAGGAAAGTGTCCAGTTTAATAATTTGGCTCTTATTATTGTGGACGAGCAGCATCGCTTTGGC
GTACACCAGCGTTTAGCATTACGTGAAAAAGGGCGCTCAGGTGATTTTGCTCCGCATCAGTTAACCATGACGGCAACCCC
TATACCAAGAACGCTGGCGATGACAGCTTATGCGGATCTTAATGTCTCGGTCATTGATGAACTGCCACCGGGAAGAACGG
CCATTAAAACCGTTGCACTGGTTGATAAGCGTCGTGACGAGGTTATTCAGCGGGTTTACCAGGCATGTAAAAATGAGGGG
CGGCAGGCCTATTGGGTATGCACTTTGATTGAAGAATCGGAAGTATTGGAATGCCAGACAGCAGAAAATACCGCTAATGA
GATGCAGTTGGCGCTTCCAGATCTTCGTATCGGCCTTGTTCACGGACGTATGAAGGCTAACGAAAAGCAGTCTGTTATGG
ACGCTTTTAAAGAGGGGCAGCTGGATTTATTAGTTGCAACAACAGTCATTGAGGTGGGTGTGGATGTGCCTAATGCCAGC
CTGATGATTATTGAAAATCCGGAACGACTTGGACTGGCGCAATTGCACCAGTTGCGTGGTCGAGTAGGACGAGGTGAAGT
GGCCAGCCATTGTGTTTTGCTATATAAAAATCCACTGTCGAAAACCGCCCAAAGACGTTTGCAGGTGTTGCGTGAAAGCA
ATGATGGTTTTTATATTGCCGAACAGGATCTGGCTATTCGCGGTCCTGGTGAAGTGTTAGGCACCAGACAGACGGGCGTT
GCTGAATTTAAAATAGCTGATTTGCTGCGCGATCAAAGTTTATTACCGCAAGCGCAGCAATTGGCCTTTCAGCTGATGCA
TTCTTTCCCTGAGTTAATTCCAGAACTTATCCAGCGTTGGTTAGGGGATAAGGATCGTTATGTTCATGCCTAG

Upstream 100 bases:

>100_bases
TTTCCTTGATAAATTATGCTAAAAGAACTAATTAGTGCAACTTAAAGCATAATAGATGCAAGTTCTAATTATTGTCGAGT
TTAACTGTTTGGGGTTTAAA

Downstream 100 bases:

>100_bases
CCATAGCGGCAGTCTTGAAAAATTAGCGGGTAAAAAAAAGTACTTGCTGCAATATGTCGTTAGGAGAAGGAGATGAAACG
TTGTTTTGTCACTGGCGCTT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 690; Mature: 690

Protein sequence:

>690_residues
MKLDKMPLTALKGVGIKASQRLAKIGLHSVADLLFHLPLHYQDRTRIYAIADLKDSMQVSVQGKVLSCDLQSGKRRILKC
KISDGSGSVTLNFFHFNTAQQNSFVKGALIKCFGEFRRGYHGFEVTHPDYRLLNAMQQSHVEETLTPIYPSTEGLKQNSL
RSLTEQALLHLEQHQIDELLPTHLLAHPISLSDALFYIHRPPPDASIEQLENKTHPAQQRLIIEELSAQQISMLSLRVNA
QQHQAIAVKESGLLQDRLLQSLPFSLTNAQHRVNWEIQQDLKQTIPMMRLVQGDVGSGKTLVAAIAALSVIEAGYQVALM
APTELLAEQHLLNFQKWFAALDVSVGMLSGKMRVKEKRSQLENISLGLSKMVVGTHALFQESVQFNNLALIIVDEQHRFG
VHQRLALREKGRSGDFAPHQLTMTATPIPRTLAMTAYADLNVSVIDELPPGRTAIKTVALVDKRRDEVIQRVYQACKNEG
RQAYWVCTLIEESEVLECQTAENTANEMQLALPDLRIGLVHGRMKANEKQSVMDAFKEGQLDLLVATTVIEVGVDVPNAS
LMIIENPERLGLAQLHQLRGRVGRGEVASHCVLLYKNPLSKTAQRRLQVLRESNDGFYIAEQDLAIRGPGEVLGTRQTGV
AEFKIADLLRDQSLLPQAQQLAFQLMHSFPELIPELIQRWLGDKDRYVHA

Sequences:

>Translated_690_residues
MKLDKMPLTALKGVGIKASQRLAKIGLHSVADLLFHLPLHYQDRTRIYAIADLKDSMQVSVQGKVLSCDLQSGKRRILKC
KISDGSGSVTLNFFHFNTAQQNSFVKGALIKCFGEFRRGYHGFEVTHPDYRLLNAMQQSHVEETLTPIYPSTEGLKQNSL
RSLTEQALLHLEQHQIDELLPTHLLAHPISLSDALFYIHRPPPDASIEQLENKTHPAQQRLIIEELSAQQISMLSLRVNA
QQHQAIAVKESGLLQDRLLQSLPFSLTNAQHRVNWEIQQDLKQTIPMMRLVQGDVGSGKTLVAAIAALSVIEAGYQVALM
APTELLAEQHLLNFQKWFAALDVSVGMLSGKMRVKEKRSQLENISLGLSKMVVGTHALFQESVQFNNLALIIVDEQHRFG
VHQRLALREKGRSGDFAPHQLTMTATPIPRTLAMTAYADLNVSVIDELPPGRTAIKTVALVDKRRDEVIQRVYQACKNEG
RQAYWVCTLIEESEVLECQTAENTANEMQLALPDLRIGLVHGRMKANEKQSVMDAFKEGQLDLLVATTVIEVGVDVPNAS
LMIIENPERLGLAQLHQLRGRVGRGEVASHCVLLYKNPLSKTAQRRLQVLRESNDGFYIAEQDLAIRGPGEVLGTRQTGV
AEFKIADLLRDQSLLPQAQQLAFQLMHSFPELIPELIQRWLGDKDRYVHA
>Mature_690_residues
MKLDKMPLTALKGVGIKASQRLAKIGLHSVADLLFHLPLHYQDRTRIYAIADLKDSMQVSVQGKVLSCDLQSGKRRILKC
KISDGSGSVTLNFFHFNTAQQNSFVKGALIKCFGEFRRGYHGFEVTHPDYRLLNAMQQSHVEETLTPIYPSTEGLKQNSL
RSLTEQALLHLEQHQIDELLPTHLLAHPISLSDALFYIHRPPPDASIEQLENKTHPAQQRLIIEELSAQQISMLSLRVNA
QQHQAIAVKESGLLQDRLLQSLPFSLTNAQHRVNWEIQQDLKQTIPMMRLVQGDVGSGKTLVAAIAALSVIEAGYQVALM
APTELLAEQHLLNFQKWFAALDVSVGMLSGKMRVKEKRSQLENISLGLSKMVVGTHALFQESVQFNNLALIIVDEQHRFG
VHQRLALREKGRSGDFAPHQLTMTATPIPRTLAMTAYADLNVSVIDELPPGRTAIKTVALVDKRRDEVIQRVYQACKNEG
RQAYWVCTLIEESEVLECQTAENTANEMQLALPDLRIGLVHGRMKANEKQSVMDAFKEGQLDLLVATTVIEVGVDVPNAS
LMIIENPERLGLAQLHQLRGRVGRGEVASHCVLLYKNPLSKTAQRRLQVLRESNDGFYIAEQDLAIRGPGEVLGTRQTGV
AEFKIADLLRDQSLLPQAQQLAFQLMHSFPELIPELIQRWLGDKDRYVHA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=688, Percent_Identity=61.3372093023256, Blast_Score=848, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=390, Percent_Identity=38.4615384615385, Blast_Score=242, Evalue=7e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77254; Mature: 77254

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDKMPLTALKGVGIKASQRLAKIGLHSVADLLFHLPLHYQDRTRIYAIADLKDSMQVS
CCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEE
VQGKVLSCDLQSGKRRILKCKISDGSGSVTLNFFHFNTAQQNSFVKGALIKCFGEFRRGY
EECEEEEEECCCCCEEEEEEEECCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCC
HGFEVTHPDYRLLNAMQQSHVEETLTPIYPSTEGLKQNSLRSLTEQALLHLEQHQIDELL
CCCEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
PTHLLAHPISLSDALFYIHRPPPDASIEQLENKTHPAQQRLIIEELSAQQISMLSLRVNA
HHHHHHCCCCCCCEEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHCHHHEEHHHEEECC
QQHQAIAVKESGLLQDRLLQSLPFSLTNAQHRVNWEIQQDLKQTIPMMRLVQGDVGSGKT
CCCCEEEECCCCCHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHHHHHHHHCCCCCCCHH
LVAAIAALSVIEAGYQVALMAPTELLAEQHLLNFQKWFAALDVSVGMLSGKMRVKEKRSQ
HHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LENISLGLSKMVVGTHALFQESVQFNNLALIIVDEQHRFGVHQRLALREKGRSGDFAPHQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHCCHHHHHHHHHCCCCCCCCCCE
LTMTATPIPRTLAMTAYADLNVSVIDELPPGRTAIKTVALVDKRRDEVIQRVYQACKNEG
EEEECCCCCCHHEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RQAYWVCTLIEESEVLECQTAENTANEMQLALPDLRIGLVHGRMKANEKQSVMDAFKEGQ
CEEEEEEEEECCCCEEEEECCCCCHHHHEEECCCEEEEEEECCCCCCHHHHHHHHHHCCC
LDLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGEVASHCVLLYKNPLS
EEEEHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCHHHEEEEEECCCHH
KTAQRRLQVLRESNDGFYIAEQDLAIRGPGEVLGTRQTGVAEFKIADLLRDQSLLPQAQQ
HHHHHHHHHHHCCCCCEEEEECCEEEECCCHHCCCCCCCCHHHHHHHHHHCHHCCCHHHH
LAFQLMHSFPELIPELIQRWLGDKDRYVHA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKLDKMPLTALKGVGIKASQRLAKIGLHSVADLLFHLPLHYQDRTRIYAIADLKDSMQVS
CCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEE
VQGKVLSCDLQSGKRRILKCKISDGSGSVTLNFFHFNTAQQNSFVKGALIKCFGEFRRGY
EECEEEEEECCCCCEEEEEEEECCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCC
HGFEVTHPDYRLLNAMQQSHVEETLTPIYPSTEGLKQNSLRSLTEQALLHLEQHQIDELL
CCCEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
PTHLLAHPISLSDALFYIHRPPPDASIEQLENKTHPAQQRLIIEELSAQQISMLSLRVNA
HHHHHHCCCCCCCEEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHCHHHEEHHHEEECC
QQHQAIAVKESGLLQDRLLQSLPFSLTNAQHRVNWEIQQDLKQTIPMMRLVQGDVGSGKT
CCCCEEEECCCCCHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHHHHHHHHCCCCCCCHH
LVAAIAALSVIEAGYQVALMAPTELLAEQHLLNFQKWFAALDVSVGMLSGKMRVKEKRSQ
HHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LENISLGLSKMVVGTHALFQESVQFNNLALIIVDEQHRFGVHQRLALREKGRSGDFAPHQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHCCHHHHHHHHHCCCCCCCCCCE
LTMTATPIPRTLAMTAYADLNVSVIDELPPGRTAIKTVALVDKRRDEVIQRVYQACKNEG
EEEECCCCCCHHEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RQAYWVCTLIEESEVLECQTAENTANEMQLALPDLRIGLVHGRMKANEKQSVMDAFKEGQ
CEEEEEEEEECCCCEEEEECCCCCHHHHEEECCCEEEEEEECCCCCCHHHHHHHHHHCCC
LDLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGEVASHCVLLYKNPLS
EEEEHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCHHHEEEEEECCCHH
KTAQRRLQVLRESNDGFYIAEQDLAIRGPGEVLGTRQTGVAEFKIADLLRDQSLLPQAQQ
HHHHHHHHHHHCCCCCEEEEECCEEEECCCHHCCCCCCCCHHHHHHHHHHCHHCCCHHHH
LAFQLMHSFPELIPELIQRWLGDKDRYVHA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]