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The map label for this gene is dtd

Identifier: 119947083

GI number: 119947083

Start: 4307005

End: 4307442

Strand: Reverse

Name: dtd

Synonym: Ping_3481

Alternate gene names: 119947083

Gene position: 4307442-4307005 (Counterclockwise)

Preceding gene: 119947084

Following gene: 119947082

Centisome position: 94.47

GC content: 44.29

Gene sequence:

>438_bases
ATGATAGCCCTTATACAGCGTGTTAGTGACGCCAGAGTTACCGTTGCCGGAGAAAATATTGGTCAAATAGGGCCTGGGTT
ACTGGTTTTATTAGGCGTTGAAAAAGAGGATGATGAAGCTAAATGCAAACGTCTGGCACAACGGGTACTCGCTTATCGAA
TATTTGCCGACGGCGACGATAAAATGAATCTTAATGTGCAGCAAGCAGGAGGGAAAATTTTAGTTATTTCACAATTTACT
CTGGCGGCACAAACGAATAAGGGCAATCGTCCAGGTTTTTCAAAGGGCGCGGAGCCGATCGAGGCCAAACGCCTTTACAA
ACTGTTTAATAAAAACTGTTCAGAGATGGGTATTAAGGTTGAAACGGGAGAGTTTGCTGCTGATATGCAGGTCAGTTCAA
CTAACGATGGCCCAGTAACCTTTTGGCTGCAGATTTAG

Upstream 100 bases:

>100_bases
TAATTGTTTTAATCGGTGCTGAAGTCACTGCGACATTAGAAGAGTTTTTAAAGCAGCAGGAAGACAACAATGTGACTAAA
GAATATTTGGGAGCGGACAT

Downstream 100 bases:

>100_bases
TCCCTATTTATTTTTCTGGATTTTTTTGAACATTTTTCTTTAACCCGAGAGAACTTTCTTTTCAGTTAAACTTATTGCAT
AGTGGATTGTCTTATAGCAG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MIALIQRVSDARVTVAGENIGQIGPGLLVLLGVEKEDDEAKCKRLAQRVLAYRIFADGDDKMNLNVQQAGGKILVISQFT
LAAQTNKGNRPGFSKGAEPIEAKRLYKLFNKNCSEMGIKVETGEFAADMQVSSTNDGPVTFWLQI

Sequences:

>Translated_145_residues
MIALIQRVSDARVTVAGENIGQIGPGLLVLLGVEKEDDEAKCKRLAQRVLAYRIFADGDDKMNLNVQQAGGKILVISQFT
LAAQTNKGNRPGFSKGAEPIEAKRLYKLFNKNCSEMGIKVETGEFAADMQVSSTNDGPVTFWLQI
>Mature_145_residues
MIALIQRVSDARVTVAGENIGQIGPGLLVLLGVEKEDDEAKCKRLAQRVLAYRIFADGDDKMNLNVQQAGGKILVISQFT
LAAQTNKGNRPGFSKGAEPIEAKRLYKLFNKNCSEMGIKVETGEFAADMQVSSTNDGPVTFWLQI

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=147, Percent_Identity=37.4149659863946, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=66.2068965517241, Blast_Score=198, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI115533292, Length=143, Percent_Identity=38.4615384615385, Blast_Score=90, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=41.8918918918919, Blast_Score=99, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=39.041095890411, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_PSYIN (A1T099)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944763.1
- ProteinModelPortal:   A1T099
- SMR:   A1T099
- STRING:   A1T099
- GeneID:   4625554
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3481
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   A1T099
- BioCyc:   PING357804:PING_3481-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 15801; Mature: 15801

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALIQRVSDARVTVAGENIGQIGPGLLVLLGVEKEDDEAKCKRLAQRVLAYRIFADGDD
CCCEEEECCCCEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCC
KMNLNVQQAGGKILVISQFTLAAQTNKGNRPGFSKGAEPIEAKRLYKLFNKNCSEMGIKV
CEEEEEECCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCEEE
ETGEFAADMQVSSTNDGPVTFWLQI
ECCCCEEEEEEECCCCCCEEEEEEC
>Mature Secondary Structure
MIALIQRVSDARVTVAGENIGQIGPGLLVLLGVEKEDDEAKCKRLAQRVLAYRIFADGDD
CCCEEEECCCCEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCC
KMNLNVQQAGGKILVISQFTLAAQTNKGNRPGFSKGAEPIEAKRLYKLFNKNCSEMGIKV
CEEEEEECCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCEEE
ETGEFAADMQVSSTNDGPVTFWLQI
ECCCCEEEEEEECCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA