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The map label for this gene is (rmlA1 [H]

Identifier: 119947066

GI number: 119947066

Start: 4284758

End: 4285639

Strand: Reverse

Name: (rmlA1 [H]

Synonym: Ping_3464

Alternate gene names: 119947066

Gene position: 4285639-4284758 (Counterclockwise)

Preceding gene: 119947067

Following gene: 119947065

Centisome position: 93.99

GC content: 36.62

Gene sequence:

>882_bases
ATGAAAGGCATTATCTTAGCTGGTGGCTCGGGAACGCGTTTATACCCGATTACTCGTGGTGTTTCAAAGCAACTATTACC
AGTATATGACAAACCAATGGTTTATTATCCAATATCGACATTAATGTTAGCTGGAATCAAAGATATTTTGATTATTACTA
CTCCAGAAGATATTGACAGTTTTAAACGATTATTGGGTGATGGTAACGATATTGGTGTTAATTTTGAATATGCGATTCAG
CCAAGTCCAGATGGGTTAGCTCAAGCGTTTATTATCGGTGAAAAATTCATTGATGGGGATTCTTGTTGCCTGGTTTTGGG
AGACAATATTTTCTATGGACAATCCTTTAGTCAGACTTTAAAAAATTCAGCTAGTCGAACAAAAGGAGCAACAGTCTTTG
GTTATCAGGTAAAAGACCCTGAACGTTTTGGTGTCATTGATTTTGATAAGAATATGAGAGCGCTTTCGATTGAAGAAAAG
CCAGCTAAGCCAAAATCTAACTATGCGGTCACTGGGTTATATTTTTATGACAATCGCGTTGTTGATTTTGCTAAAAAAGT
AAAGCCTTCTCACCGAGGTGAACTAGAAATTACTAGCATTAATCAAATGTATCTTGATGATAATTCTTTGAATGTTGAAT
TGCTAGGACGCGGTTTTGCCTGGCTTGATACTGGTACTCATGAAAGCTTGCATGAAGCTTCATCTTTTGTGCAGACTATT
GAAAATGTTCAAGGATTAAAGGTTGCTTGCCTTGAAGAGATATCGTGGCGTAATAATTGGTTAAGTGATGAACAGGTTCT
TGCACTTGCTAATCCTATGATGAAAAACGAATATGGGCAATACCTAAAACGTTTAATTGAAGAATCAAAAGCGAAGGCAT
AA

Upstream 100 bases:

>100_bases
TCGAGTGGTACCTAAATAATAAAAAATGGTGGAGCCGTGTTCTTGATGGTTCATATAATTTTGAGCGTCTAGGCACAGCA
AGTACAAGTGAGGAGAATAA

Downstream 100 bases:

>100_bases
AGATATGCGCGTATTAATAACCGGAAGTAAAGGACAGGTTGGTCATTGCCTAACGGAACAGTTAAGAAATTATACTGATG
CACAGTTTTTAGCGTTAGAT

Product: glucose-1-phosphate thymidylyltransferase

Products: NA

Alternate protein names: dTDP-glucose pyrophosphorylase; dTDP-glucose synthase [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMVYYPISTLMLAGIKDILIITTPEDIDSFKRLLGDGNDIGVNFEYAIQ
PSPDGLAQAFIIGEKFIDGDSCCLVLGDNIFYGQSFSQTLKNSASRTKGATVFGYQVKDPERFGVIDFDKNMRALSIEEK
PAKPKSNYAVTGLYFYDNRVVDFAKKVKPSHRGELEITSINQMYLDDNSLNVELLGRGFAWLDTGTHESLHEASSFVQTI
ENVQGLKVACLEEISWRNNWLSDEQVLALANPMMKNEYGQYLKRLIEESKAKA

Sequences:

>Translated_293_residues
MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMVYYPISTLMLAGIKDILIITTPEDIDSFKRLLGDGNDIGVNFEYAIQ
PSPDGLAQAFIIGEKFIDGDSCCLVLGDNIFYGQSFSQTLKNSASRTKGATVFGYQVKDPERFGVIDFDKNMRALSIEEK
PAKPKSNYAVTGLYFYDNRVVDFAKKVKPSHRGELEITSINQMYLDDNSLNVELLGRGFAWLDTGTHESLHEASSFVQTI
ENVQGLKVACLEEISWRNNWLSDEQVLALANPMMKNEYGQYLKRLIEESKAKA
>Mature_293_residues
MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMVYYPISTLMLAGIKDILIITTPEDIDSFKRLLGDGNDIGVNFEYAIQ
PSPDGLAQAFIIGEKFIDGDSCCLVLGDNIFYGQSFSQTLKNSASRTKGATVFGYQVKDPERFGVIDFDKNMRALSIEEK
PAKPKSNYAVTGLYFYDNRVVDFAKKVKPSHRGELEITSINQMYLDDNSLNVELLGRGFAWLDTGTHESLHEASSFVQTI
ENVQGLKVACLEEISWRNNWLSDEQVLALANPMMKNEYGQYLKRLIEESKAKA

Specific function: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis [H]

COG id: COG1209

COG function: function code M; dTDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate thymidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790224, Length=286, Percent_Identity=72.7272727272727, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI1788351, Length=288, Percent_Identity=65.2777777777778, Blast_Score=408, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI133931050, Length=229, Percent_Identity=25.3275109170306, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6320148, Length=196, Percent_Identity=29.5918367346939, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355443, Length=228, Percent_Identity=25.4385964912281, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644084, Length=228, Percent_Identity=25.4385964912281, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005907
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.24 [H]

Molecular weight: Translated: 32706; Mature: 32706

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMVYYPISTLMLAGIKDILIITTPEDIDS
CCCEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEECHHHHHHHCCCEEEEEECCHHHHH
FKRLLGDGNDIGVNFEYAIQPSPDGLAQAFIIGEKFIDGDSCCLVLGDNIFYGQSFSQTL
HHHHHCCCCEEEEEEEEEECCCCCHHHHEEEEHHEEECCCCEEEEECCCEEECCCHHHHH
KNSASRTKGATVFGYQVKDPERFGVIDFDKNMRALSIEEKPAKPKSNYAVTGLYFYDNRV
HHHHCCCCCCEEEEEEECCCCCEEEEEECCCCEEEEECCCCCCCCCCEEEEEEEEECCHH
VDFAKKVKPSHRGELEITSINQMYLDDNSLNVELLGRGFAWLDTGTHESLHEASSFVQTI
HHHHHHCCCCCCCEEEEEEEEEEEECCCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHH
ENVQGLKVACLEEISWRNNWLSDEQVLALANPMMKNEYGQYLKRLIEESKAKA
HHCCCCCHHHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMVYYPISTLMLAGIKDILIITTPEDIDS
CCCEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEECHHHHHHHCCCEEEEEECCHHHHH
FKRLLGDGNDIGVNFEYAIQPSPDGLAQAFIIGEKFIDGDSCCLVLGDNIFYGQSFSQTL
HHHHHCCCCEEEEEEEEEECCCCCHHHHEEEEHHEEECCCCEEEEECCCEEECCCHHHHH
KNSASRTKGATVFGYQVKDPERFGVIDFDKNMRALSIEEKPAKPKSNYAVTGLYFYDNRV
HHHHCCCCCCEEEEEEECCCCCEEEEEECCCCEEEEECCCCCCCCCCEEEEEEEEECCHH
VDFAKKVKPSHRGELEITSINQMYLDDNSLNVELLGRGFAWLDTGTHESLHEASSFVQTI
HHHHHHCCCCCCCEEEEEEEEEEEECCCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHH
ENVQGLKVACLEEISWRNNWLSDEQVLALANPMMKNEYGQYLKRLIEESKAKA
HHCCCCCHHHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]