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The map label for this gene is oadA [H]

Identifier: 119946981

GI number: 119946981

Start: 4168927

End: 4170741

Strand: Reverse

Name: oadA [H]

Synonym: Ping_3376

Alternate gene names: 119946981

Gene position: 4170741-4168927 (Counterclockwise)

Preceding gene: 119946982

Following gene: 119946980

Centisome position: 91.47

GC content: 44.46

Gene sequence:

>1815_bases
ATGAAGGAGCAAGTAAATATGTCTAAGCCTCTCGGCATCACTGAAGTTGTCCTACGCGATGCGCATCAATCATTATTTGC
AACACGGATGCGCACTGAGGATATGTTACCTATTGCGGAGAAGTTGGATAAAATTGGCTTCTGGTCATTAGAGACATGGG
GTGGGGCTACATTTGATTCCTGTATCCGCTTTTTAGGAGAAGATCCATGGGAACGCCTGCGTGCTTTAAAAGCAGCCATG
CCTAATACGCCTCAGCAAATGTTATTACGCGGTCAAAATTTATTAGGTTACCGCCATTATGCCGATGATGTTGTTGAAAA
ATTTGTAGAGCGTGCCCATACCAATGGTGTGGATGTCTTCCGTATATTTGATGCAATGAATGATGTGCGCAATTTTGAAA
CCGCGGTTAAATCGGCGGTTAAAATTGGTGCGCACGCCCAGGGTGCTATTTCTTATACCACTAGCCCTGTGCACACTGTT
GATAACTGGGTCGATATGGCAAAACGCCTTGAGGATATGGGATGTCATTCTTTATGTATTAAAGATATGGCGGGTTTATT
AAAGCCCTATGTTGCAGAAGAGTTGATTACAAAAATCAAGGCAAGTACCAATATTCCGTTAGCGTTACATTGTCATGCAA
CGACTGGCCTTAGCATCGCAACGCACCAAAAAGCGATTGATTCCGGTATTGATATTATTGATTCTGCCATCTCTTCTATG
TCGATGACCTATGGACATACTCCAACTGAAACACTTGTTTCAATTGTTGAAGGTGAAGCGCGAGATACGGGTCTAGAACT
GCCTAAACTTGCAGAGATATCCGCTTACTTTCGTGATGTCCGTAAAAAATATGTGAAATTTGAAGGTGAATTAAAAGGTG
TTGATCCGCGCATCCTGATTGCCCAAGTGCCCGGCGGCATGTTAACTAACATGGAAAGCCAGCTTAAAGAGCAGGGCGCT
GCAGACAAGATGGATCAAGTGTTGGCCGAAATCACCGCAGTGCGTAAAGATCTTGGTTATATTCCGCTGGTTACCCCGAC
CTCTCAAATTGTCGGTACGCAAGCTGTTATTAATGTATTGATGGGCGAGCGTTATAAAAATATAACCAAAGAAACTGCCG
GCGTGTTAAAAGGAGAGTATGGCGCAACACCAGCTCCTGTTAATGCTGAGCTGCAGGCGAAAGTATTAGAGGGCGGAACT
GCAATTACTTGTCGTCCTGCTGATAACATTGCGCCTGAAATGAAAAATATCCAGGCCGAATTTAAGAAACTTGCCACTGA
AAAAGGCATTAAAATTGCGCAACATGAGACTGATGATGCATTGATTTATGCTTTATTTCCTGAAATTGGTCTTAAATTTT
TAGAAAACCGTAATAACCCCGATGCATTTGAGCCCGTCCCCAGCGCTGACGATGTTAAACCAGCGGCTAAAACGGCAACT
AAGGCGCAACAAGGTGGTGCAGAAACTTATTCAGTGGCCGTTGATGGGCAATTATATACTGTCCAAGTTGGCCCTGAAGG
CAGTGTGGAAGGCATAAAAGCAGGACCGCCGAGCGCAACTTTGTCAGCCTCAGCCTCAGCTTCAACCGAAGCGACAGTGA
TGAGCGAGGAATTACCAGCACCATTGGCGGGTAATATCTTTAAAGTGTTGGTTAGTGAAGGTGAGAAGGTTGAGGAAGGC
GATGTGCTTTTGATAATGGAAGCGATGAAGATGGAAACTGAGATTCGAGCACCAAAATCGGGGGTTATCCAAGGCGTTTT
TGTCAAAGAAGGTTCTTCTGTTGCCGTGGGTGAAACCCTGTTTAAAATAGCTTAA

Upstream 100 bases:

>100_bases
AGCGCCACAGAATCTGCAATTAATCCCGCAATTATAGCCGCTATTACCACGGCTGTGCATCAATATCATAAAACTAAAAC
CGCACAATAGGAAATGAAAA

Downstream 100 bases:

>100_bases
GGAAGATAACGTGGATGGATTAATAACACTTTGGGCAGATACGGGTATAGCACATTTTACCTTTCCTGATCTGGTCATGA
TTGCTGTAGGTCTCTTATTA

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MKEQVNMSKPLGITEVVLRDAHQSLFATRMRTEDMLPIAEKLDKIGFWSLETWGGATFDSCIRFLGEDPWERLRALKAAM
PNTPQQMLLRGQNLLGYRHYADDVVEKFVERAHTNGVDVFRIFDAMNDVRNFETAVKSAVKIGAHAQGAISYTTSPVHTV
DNWVDMAKRLEDMGCHSLCIKDMAGLLKPYVAEELITKIKASTNIPLALHCHATTGLSIATHQKAIDSGIDIIDSAISSM
SMTYGHTPTETLVSIVEGEARDTGLELPKLAEISAYFRDVRKKYVKFEGELKGVDPRILIAQVPGGMLTNMESQLKEQGA
ADKMDQVLAEITAVRKDLGYIPLVTPTSQIVGTQAVINVLMGERYKNITKETAGVLKGEYGATPAPVNAELQAKVLEGGT
AITCRPADNIAPEMKNIQAEFKKLATEKGIKIAQHETDDALIYALFPEIGLKFLENRNNPDAFEPVPSADDVKPAAKTAT
KAQQGGAETYSVAVDGQLYTVQVGPEGSVEGIKAGPPSATLSASASASTEATVMSEELPAPLAGNIFKVLVSEGEKVEEG
DVLLIMEAMKMETEIRAPKSGVIQGVFVKEGSSVAVGETLFKIA

Sequences:

>Translated_604_residues
MKEQVNMSKPLGITEVVLRDAHQSLFATRMRTEDMLPIAEKLDKIGFWSLETWGGATFDSCIRFLGEDPWERLRALKAAM
PNTPQQMLLRGQNLLGYRHYADDVVEKFVERAHTNGVDVFRIFDAMNDVRNFETAVKSAVKIGAHAQGAISYTTSPVHTV
DNWVDMAKRLEDMGCHSLCIKDMAGLLKPYVAEELITKIKASTNIPLALHCHATTGLSIATHQKAIDSGIDIIDSAISSM
SMTYGHTPTETLVSIVEGEARDTGLELPKLAEISAYFRDVRKKYVKFEGELKGVDPRILIAQVPGGMLTNMESQLKEQGA
ADKMDQVLAEITAVRKDLGYIPLVTPTSQIVGTQAVINVLMGERYKNITKETAGVLKGEYGATPAPVNAELQAKVLEGGT
AITCRPADNIAPEMKNIQAEFKKLATEKGIKIAQHETDDALIYALFPEIGLKFLENRNNPDAFEPVPSADDVKPAAKTAT
KAQQGGAETYSVAVDGQLYTVQVGPEGSVEGIKAGPPSATLSASASASTEATVMSEELPAPLAGNIFKVLVSEGEKVEEG
DVLLIMEAMKMETEIRAPKSGVIQGVFVKEGSSVAVGETLFKIA
>Mature_604_residues
MKEQVNMSKPLGITEVVLRDAHQSLFATRMRTEDMLPIAEKLDKIGFWSLETWGGATFDSCIRFLGEDPWERLRALKAAM
PNTPQQMLLRGQNLLGYRHYADDVVEKFVERAHTNGVDVFRIFDAMNDVRNFETAVKSAVKIGAHAQGAISYTTSPVHTV
DNWVDMAKRLEDMGCHSLCIKDMAGLLKPYVAEELITKIKASTNIPLALHCHATTGLSIATHQKAIDSGIDIIDSAISSM
SMTYGHTPTETLVSIVEGEARDTGLELPKLAEISAYFRDVRKKYVKFEGELKGVDPRILIAQVPGGMLTNMESQLKEQGA
ADKMDQVLAEITAVRKDLGYIPLVTPTSQIVGTQAVINVLMGERYKNITKETAGVLKGEYGATPAPVNAELQAKVLEGGT
AITCRPADNIAPEMKNIQAEFKKLATEKGIKIAQHETDDALIYALFPEIGLKFLENRNNPDAFEPVPSADDVKPAAKTAT
KAQQGGAETYSVAVDGQLYTVQVGPEGSVEGIKAGPPSATLSASASASTEATVMSEELPAPLAGNIFKVLVSEGEKVEEG
DVLLIMEAMKMETEIRAPKSGVIQGVFVKEGSSVAVGETLFKIA

Specific function: Lyase and sodium transporter [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=639, Percent_Identity=28.7949921752739, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI106049295, Length=639, Percent_Identity=28.7949921752739, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI106049292, Length=639, Percent_Identity=28.7949921752739, Blast_Score=261, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17562816, Length=636, Percent_Identity=31.2893081761006, Blast_Score=293, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6319695, Length=620, Percent_Identity=30.8064516129032, Blast_Score=301, Evalue=3e-82,
Organism=Saccharomyces cerevisiae, GI6321376, Length=621, Percent_Identity=30.2737520128824, Blast_Score=289, Evalue=8e-79,
Organism=Drosophila melanogaster, GI24652212, Length=651, Percent_Identity=32.5652841781874, Blast_Score=297, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24652210, Length=651, Percent_Identity=32.5652841781874, Blast_Score=297, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24652214, Length=651, Percent_Identity=32.5652841781874, Blast_Score=297, Evalue=2e-80,
Organism=Drosophila melanogaster, GI19921944, Length=651, Percent_Identity=32.5652841781874, Blast_Score=297, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24652216, Length=651, Percent_Identity=32.5652841781874, Blast_Score=297, Evalue=2e-80,
Organism=Drosophila melanogaster, GI281363050, Length=651, Percent_Identity=32.5652841781874, Blast_Score=297, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24652224, Length=651, Percent_Identity=32.5652841781874, Blast_Score=297, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24652222, Length=651, Percent_Identity=32.5652841781874, Blast_Score=297, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24652220, Length=651, Percent_Identity=32.5652841781874, Blast_Score=297, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24652218, Length=651, Percent_Identity=32.5652841781874, Blast_Score=297, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR005776
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =4.1.1.3 [H]

Molecular weight: Translated: 65380; Mature: 65380

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEQVNMSKPLGITEVVLRDAHQSLFATRMRTEDMLPIAEKLDKIGFWSLETWGGATFDS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEECCCCCCHHH
CIRFLGEDPWERLRALKAAMPNTPQQMLLRGQNLLGYRHYADDVVEKFVERAHTNGVDVF
HHHHHCCCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
RIFDAMNDVRNFETAVKSAVKIGAHAQGAISYTTSPVHTVDNWVDMAKRLEDMGCHSLCI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCHHHHHH
KDMAGLLKPYVAEELITKIKASTNIPLALHCHATTGLSIATHQKAIDSGIDIIDSAISSM
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SMTYGHTPTETLVSIVEGEARDTGLELPKLAEISAYFRDVRKKYVKFEGELKGVDPRILI
HHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
AQVPGGMLTNMESQLKEQGAADKMDQVLAEITAVRKDLGYIPLVTPTSQIVGTQAVINVL
EECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHH
MGERYKNITKETAGVLKGEYGATPAPVNAELQAKVLEGGTAITCRPADNIAPEMKNIQAE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHEECCCCEEEECCCCCCCHHHHHHHHH
FKKLATEKGIKIAQHETDDALIYALFPEIGLKFLENRNNPDAFEPVPSADDVKPAAKTAT
HHHHHHHCCCEEEECCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
KAQQGGAETYSVAVDGQLYTVQVGPEGSVEGIKAGPPSATLSASASASTEATVMSEELPA
HHHHCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHCCC
PLAGNIFKVLVSEGEKVEEGDVLLIMEAMKMETEIRAPKSGVIQGVFVKEGSSVAVGETL
CHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCEEEEEEECCCCEEHHHHH
FKIA
HHCC
>Mature Secondary Structure
MKEQVNMSKPLGITEVVLRDAHQSLFATRMRTEDMLPIAEKLDKIGFWSLETWGGATFDS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEECCCCCCHHH
CIRFLGEDPWERLRALKAAMPNTPQQMLLRGQNLLGYRHYADDVVEKFVERAHTNGVDVF
HHHHHCCCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
RIFDAMNDVRNFETAVKSAVKIGAHAQGAISYTTSPVHTVDNWVDMAKRLEDMGCHSLCI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCHHHHHH
KDMAGLLKPYVAEELITKIKASTNIPLALHCHATTGLSIATHQKAIDSGIDIIDSAISSM
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SMTYGHTPTETLVSIVEGEARDTGLELPKLAEISAYFRDVRKKYVKFEGELKGVDPRILI
HHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
AQVPGGMLTNMESQLKEQGAADKMDQVLAEITAVRKDLGYIPLVTPTSQIVGTQAVINVL
EECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHH
MGERYKNITKETAGVLKGEYGATPAPVNAELQAKVLEGGTAITCRPADNIAPEMKNIQAE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHEECCCCEEEECCCCCCCHHHHHHHHH
FKKLATEKGIKIAQHETDDALIYALFPEIGLKFLENRNNPDAFEPVPSADDVKPAAKTAT
HHHHHHHCCCEEEECCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
KAQQGGAETYSVAVDGQLYTVQVGPEGSVEGIKAGPPSATLSASASASTEATVMSEELPA
HHHHCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHCCC
PLAGNIFKVLVSEGEKVEEGDVLLIMEAMKMETEIRAPKSGVIQGVFVKEGSSVAVGETL
CHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCEEEEEEECCCCEEHHHHH
FKIA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2454915 [H]