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The map label for this gene is yqhD [H]

Identifier: 119946955

GI number: 119946955

Start: 4138961

End: 4140118

Strand: Reverse

Name: yqhD [H]

Synonym: Ping_3349

Alternate gene names: 119946955

Gene position: 4140118-4138961 (Counterclockwise)

Preceding gene: 119946956

Following gene: 119946954

Centisome position: 90.8

GC content: 43.7

Gene sequence:

>1158_bases
ATGTTAAATTTCAGTTTTCAAAATCAGACACGTATTCATTTTGGTGAAGGTCAAATCGATAAACTCTCTACCGAGATCCC
AAAGGATGCCAAAGTATTAGTTGTTTATGGCGGTGGTTCCATAAAAAATAATGGCGTTTATGATCAGGTGGTCAATGCGT
TAAAAGATCATACTTGGTTTGAATTTTCAGGCATTGAGCCTAATCCAAAGTACGATACTTTAATGAAAGCGCAGGCCGTC
ATTAAAGAGCATGATATCGATTATATAATGGCTGTTGGTGGCGGTTCTGTGGCTGACGGTTGTAAATTTATTGCGGCAGC
AGCGCTTTATGCGGGTGATGATCCTTGGGATATTCTGGCTAAACAACAGCCGATAGAAAGTGCCTTACCGATTGGTGTTG
TGCTGACCTTACCGGCAACCGGTTCTGAGACAAATACTAATGCTGTGGTAACACGTGACGGCAATAAATTACCCTTCTCA
AGTGCTGCGGTGCGGCCACAATTTGCAGTGTTAGATCCTGCGGTTACTCTGTCGTTATCGGATCGACAAATCAGTAACGG
TGTGGTGGATGCTTTTATCCATACTATGGAGCAGTACCTTACCTATAGTGTTAGTGGAAAAGTACAAGACCGTTTTGCTG
AAGGTCTATTACAAACCTTAATTGAAGAAGGGCCTAAAGCGCTGCAGCCGGAAACCAAAGATAATCTTGACGTCCGCGCT
AATATTATGTGGTCTGCCACTATGGCATTAAATGGTCTGATTGGTGCCGGTGTACCGCAGGATTGGGCTACCCATATGAT
AGGTCATGAGCTGACGGGCGCTTACGAAATTGATCATGCGCGTACTCTGTCGATTGTTTTACCTGCAGTAATGAAAGTGC
GCCGGACAGCGAAACATGAAAAACTGCTGCAATATGCAGAGCGTGTTTGGCATATTACCCAGGGCAGTGAAGATCAGAGA
ATTGATCAAGCTATCGCCTTGACGGAAGATTTTTTCCAGAAAATGGCGATGCCTATCCGCTTGTCAGATATTGAATTAGG
CGCCGCAGATATTGATATTCTAATGGCTAATCTGGAAGGTCATGGCATGGTGGAGCTAGGTGAAACGAAAGAAATTACCC
TTGCAATCAGTCGCCAAATATTAGAACAAGCAAGTTAA

Upstream 100 bases:

>100_bases
CACAAAAGTAGCTTAAATAATAGCCGCTTAAATTAGAGCAATTTAAATATGAGCCCCTTAATTAAGTGGCTCATATTGCC
AATAAACAGTAGGAAGTCAT

Downstream 100 bases:

>100_bases
TAACCACTTTCCCTTTCTTGATACTTTAGCTGGGGAAGCTTTCAGCGCAGTGATGGCTGAAAGCTTCCCCAGTCAAAGTG
GAAAGCCCTCCTAGCACAGA

Product: alcohol dehydrogenase, iron-containing

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MLNFSFQNQTRIHFGEGQIDKLSTEIPKDAKVLVVYGGGSIKNNGVYDQVVNALKDHTWFEFSGIEPNPKYDTLMKAQAV
IKEHDIDYIMAVGGGSVADGCKFIAAAALYAGDDPWDILAKQQPIESALPIGVVLTLPATGSETNTNAVVTRDGNKLPFS
SAAVRPQFAVLDPAVTLSLSDRQISNGVVDAFIHTMEQYLTYSVSGKVQDRFAEGLLQTLIEEGPKALQPETKDNLDVRA
NIMWSATMALNGLIGAGVPQDWATHMIGHELTGAYEIDHARTLSIVLPAVMKVRRTAKHEKLLQYAERVWHITQGSEDQR
IDQAIALTEDFFQKMAMPIRLSDIELGAADIDILMANLEGHGMVELGETKEITLAISRQILEQAS

Sequences:

>Translated_385_residues
MLNFSFQNQTRIHFGEGQIDKLSTEIPKDAKVLVVYGGGSIKNNGVYDQVVNALKDHTWFEFSGIEPNPKYDTLMKAQAV
IKEHDIDYIMAVGGGSVADGCKFIAAAALYAGDDPWDILAKQQPIESALPIGVVLTLPATGSETNTNAVVTRDGNKLPFS
SAAVRPQFAVLDPAVTLSLSDRQISNGVVDAFIHTMEQYLTYSVSGKVQDRFAEGLLQTLIEEGPKALQPETKDNLDVRA
NIMWSATMALNGLIGAGVPQDWATHMIGHELTGAYEIDHARTLSIVLPAVMKVRRTAKHEKLLQYAERVWHITQGSEDQR
IDQAIALTEDFFQKMAMPIRLSDIELGAADIDILMANLEGHGMVELGETKEITLAISRQILEQAS
>Mature_385_residues
MLNFSFQNQTRIHFGEGQIDKLSTEIPKDAKVLVVYGGGSIKNNGVYDQVVNALKDHTWFEFSGIEPNPKYDTLMKAQAV
IKEHDIDYIMAVGGGSVADGCKFIAAAALYAGDDPWDILAKQQPIESALPIGVVLTLPATGSETNTNAVVTRDGNKLPFS
SAAVRPQFAVLDPAVTLSLSDRQISNGVVDAFIHTMEQYLTYSVSGKVQDRFAEGLLQTLIEEGPKALQPETKDNLDVRA
NIMWSATMALNGLIGAGVPQDWATHMIGHELTGAYEIDHARTLSIVLPAVMKVRRTAKHEKLLQYAERVWHITQGSEDQR
IDQAIALTEDFFQKMAMPIRLSDIELGAADIDILMANLEGHGMVELGETKEITLAISRQILEQAS

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789386, Length=389, Percent_Identity=58.8688946015424, Blast_Score=455, Evalue=1e-129,
Organism=Escherichia coli, GI48994951, Length=325, Percent_Identity=23.3846153846154, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082107, Length=279, Percent_Identity=25.8064516129032, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787493, Length=354, Percent_Identity=23.4463276836158, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789163, Length=370, Percent_Identity=23.7837837837838, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321181, Length=380, Percent_Identity=25.2631578947368, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42131; Mature: 42131

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFSFQNQTRIHFGEGQIDKLSTEIPKDAKVLVVYGGGSIKNNGVYDQVVNALKDHTWF
CCCCCCCCCCEEEECCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEE
EFSGIEPNPKYDTLMKAQAVIKEHDIDYIMAVGGGSVADGCKFIAAAALYAGDDPWDILA
EECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHC
KQQPIESALPIGVVLTLPATGSETNTNAVVTRDGNKLPFSSAAVRPQFAVLDPAVTLSLS
CCCCHHHCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCEEEEEEC
DRQISNGVVDAFIHTMEQYLTYSVSGKVQDRFAEGLLQTLIEEGPKALQPETKDNLDVRA
CCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
NIMWSATMALNGLIGAGVPQDWATHMIGHELTGAYEIDHARTLSIVLPAVMKVRRTAKHE
EEEEEHHHHHCCHHCCCCCHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
KLLQYAERVWHITQGSEDQRIDQAIALTEDFFQKMAMPIRLSDIELGAADIDILMANLEG
HHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCC
HGMVELGETKEITLAISRQILEQAS
CCEEEECCCCEEHHHHHHHHHHHCC
>Mature Secondary Structure
MLNFSFQNQTRIHFGEGQIDKLSTEIPKDAKVLVVYGGGSIKNNGVYDQVVNALKDHTWF
CCCCCCCCCCEEEECCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCEE
EFSGIEPNPKYDTLMKAQAVIKEHDIDYIMAVGGGSVADGCKFIAAAALYAGDDPWDILA
EECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHC
KQQPIESALPIGVVLTLPATGSETNTNAVVTRDGNKLPFSSAAVRPQFAVLDPAVTLSLS
CCCCHHHCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCEEEEEEC
DRQISNGVVDAFIHTMEQYLTYSVSGKVQDRFAEGLLQTLIEEGPKALQPETKDNLDVRA
CCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
NIMWSATMALNGLIGAGVPQDWATHMIGHELTGAYEIDHARTLSIVLPAVMKVRRTAKHE
EEEEEHHHHHCCHHCCCCCHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
KLLQYAERVWHITQGSEDQRIDQAIALTEDFFQKMAMPIRLSDIELGAADIDILMANLEG
HHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCC
HGMVELGETKEITLAISRQILEQAS
CCEEEECCCCEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]