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The map label for this gene is frdD [H]

Identifier: 119946887

GI number: 119946887

Start: 4047804

End: 4048181

Strand: Direct

Name: frdD [H]

Synonym: Ping_3281

Alternate gene names: 119946887

Gene position: 4047804-4048181 (Clockwise)

Preceding gene: 119946886

Following gene: 119946889

Centisome position: 88.78

GC content: 42.59

Gene sequence:

>378_bases
ATGTCTAATACAACAGAGAAAATCTATACACGTTCACATGAACCCATTTTCTGGGGGTTATTTGGTGCGGGAGGAATGCT
CACCGCGTTCCTGACACCCGTCATGATTTTGATTACCGGTATTCTAATTCCGCTTGGTTTAATAGATAGTAAGAACCTTA
GTTATGAAAAAGTGCATCACTTTGCCACAAGCTGGTACGGTGCAGCTATTGTATTAGTGCTGGTTGCTTTACCTTTATGG
CATACCCTGCATCGTATTTACCATGGGTTACACGATATAGGCATAAAACGAGGACGAGATTTGCAACAGGTTTTCTGTTA
CGGGTTTGCTTTTGCGGTCAGTGTCTTTGTCTTTACTCTGCTGCTGCAGATGTTCTAG

Upstream 100 bases:

>100_bases
AAAGATTACCAGACAAATTTATTATTGCGGGTCATTACGGCGCATTCGTTGCAGTGACTATTTTCTGCCTGATAATTATC
ACCCTGTAAGGAGAATGAAA

Downstream 100 bases:

>100_bases
TGGTTTCCCGTTCATAGAGATAAAAAAACCAGCTAATTAGCTGATTTTTTTATCTTGATACTCACATCACTAAAGATATC
AGAAAAGTTTATTTTTTAAC

Product: fumarate reductase, D subunit

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 124

Protein sequence:

>125_residues
MSNTTEKIYTRSHEPIFWGLFGAGGMLTAFLTPVMILITGILIPLGLIDSKNLSYEKVHHFATSWYGAAIVLVLVALPLW
HTLHRIYHGLHDIGIKRGRDLQQVFCYGFAFAVSVFVFTLLLQMF

Sequences:

>Translated_125_residues
MSNTTEKIYTRSHEPIFWGLFGAGGMLTAFLTPVMILITGILIPLGLIDSKNLSYEKVHHFATSWYGAAIVLVLVALPLW
HTLHRIYHGLHDIGIKRGRDLQQVFCYGFAFAVSVFVFTLLLQMF
>Mature_124_residues
SNTTEKIYTRSHEPIFWGLFGAGGMLTAFLTPVMILITGILIPLGLIDSKNLSYEKVHHFATSWYGAAIVLVLVALPLWH
TLHRIYHGLHDIGIKRGRDLQQVFCYGFAFAVSVFVFTLLLQMF

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane [H]

COG id: COG3080

COG function: function code C; Fumarate reductase subunit D

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdD family [H]

Homologues:

Organism=Escherichia coli, GI1790594, Length=95, Percent_Identity=52.6315789473684, Blast_Score=102, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003418
- ProDom:   PD015693 [H]

Pfam domain/function: PF02313 Fumarate_red_D [H]

EC number: 1.3.99.1

Molecular weight: Translated: 14126; Mature: 13995

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTTEKIYTRSHEPIFWGLFGAGGMLTAFLTPVMILITGILIPLGLIDSKNLSYEKVHH
CCCCHHHHHHCCCCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
FATSWYGAAIVLVLVALPLWHTLHRIYHGLHDIGIKRGRDLQQVFCYGFAFAVSVFVFTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LLQMF
HHHHC
>Mature Secondary Structure 
SNTTEKIYTRSHEPIFWGLFGAGGMLTAFLTPVMILITGILIPLGLIDSKNLSYEKVHH
CCCHHHHHHCCCCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
FATSWYGAAIVLVLVALPLWHTLHRIYHGLHDIGIKRGRDLQQVFCYGFAFAVSVFVFTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LLQMF
HHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA