Click here to switch to the map view.

The map label for this gene is mviN [H]

Identifier: 119946879

GI number: 119946879

Start: 4039310

End: 4040875

Strand: Reverse

Name: mviN [H]

Synonym: Ping_3273

Alternate gene names: 119946879

Gene position: 4040875-4039310 (Counterclockwise)

Preceding gene: 119946881

Following gene: 119946878

Centisome position: 88.62

GC content: 40.93

Gene sequence:

>1566_bases
GTGAGTAAAAAATTACTGAGATCAGGTTTGATCGTAAGCTCTATGACATTGATTTCTAGAATTTTAGGTCTGCTAAGAGA
TGTCGTCATAGCAAACTTGATGGGAGCGGGAGCTGCCGCCGATGTGTTTTTCTTTGCCAATAAAATTCCTAATTTTTTAC
GGCGTTTATTTGCTGAAGGTGCGTTTGCACAAGCATTTGTGCCGGTCTTGACGGAATACGAAAAACAACACTCTTTTGAT
GAAGTTAAAAAATTAGTTGCCGCTGTCTCCGGCACCTTGGGAACCATTATTACTATTATTACTATTCTCGGTGTGTTGGG
ATCTTCTGTGATCACCGCATTATTCGGTTTTGGCTGGTTTTTAGAATGGTGGAATGGCGGCCCGGATGGACAAAAGTTTG
AGCTTGCCTCTTTTATGTTAAAAATAACCTTTCCCTATTTATGGTTTATTACCTTCACCGCTTTATCCGGGGCAATTTTA
AATACTCTGGGTAAATTTGCTGTCGCCGCTTTTACGCCCGTCTTTTTGAATGTGGCAATTATCAGTTGTGCAATTTTTGT
CTCCCCGCATTTGCAACAACCAGAAATAGGGTTAGCAATAGGCGTATTTTTGGGTGGGGCGATCCAGTTTCTTTTCCAGA
TCCCTTTTTTACATAAAGAAAAACTATTGGTTAAGCCTACTTGGAATTGGCACCATCCCGGTGTTGTAAAAATCAGAGTC
TTAATGATTCCGGCATTATTTGGGGTATCTGTTAGCCAAATTAATTTATTGCTTGATACTTTTATTGCCAGTTTTCTGCA
AACGGGATCAATCAGTTGGTTATATTACTCGGATCGTTTACTGGAATTTCCATTAGGGTTATTTGGTATCGCTATCGCAA
CGGTTATTTTACCGAGCCTGTCCTCATCTCACGTCACTAAATCAATCGATGATTTTGCTAAAACGCTGGATTGGGGGATG
CGTATGGTCTGTATCTTAGGTTTCCCTGCGATGTTAGGGTTGATTATACTGGCGGAGCCTATGCTGCGTGTTTTATTTAT
GCGTGGTGAATTTGTTGCCCACGATGTTGCAATGGCATCAATGAGCTTATGGGCATACGGCAGTGGGTTATTGAGTTTTA
TGATGGTTAAAATATTAGCACCCGGATACTACGCACGCCAGGATACAAGAACGCCAGTAAAATACGGGATGATTGCTATG
GGCAGTAATATGGTTTTGAACATTATTTTTGCTATCCCCTATGGTTACGTCGGTTTGGCTATTGCAACCTCAATTTCAGC
GACTTTAAATGCAGGCTTGTTATGGTTTGGTTTATACCAAAAAGGTATTTACCAAAGACAAAAAGACAGTGTGTCGGTAC
TACTGCGAATTATCATTGCGGGTTTAGTGATGGCCGCAGGTTTAGTTGCCTTTAATCCAGCATTATCAGAGTGGAGTCAA
CTGTCGTGGCTGGAAGCTGCATTAAAACTGTTTTATTTAATCGTGGCAGGTGCAGTCTTGTATTTGTTTGCTTTAGGGTT
GACCGGATTACGCTTTAGGCATTTTCAGATAAGAATGGCTAAATGA

Upstream 100 bases:

>100_bases
ATTAACGAACGCTGACTAGTCATACTCCAGCTAACTTGTTGAGTGCCTTTTTCAAATAGTTTGAACAAAATTAACATCCC
CCTTTAGTAGGAAAAATATT

Downstream 100 bases:

>100_bases
GGGCTGATTAGTTGCGCTGCTTAATATATAATCCACTCTTTTGTGTTTTATAGCCTTTTATTAAGTAAACAAAATGGAAT
TATTACGCGGCATTCACAAT

Product: integral membrane protein MviN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MSKKLLRSGLIVSSMTLISRILGLLRDVVIANLMGAGAAADVFFFANKIPNFLRRLFAEGAFAQAFVPVLTEYEKQHSFD
EVKKLVAAVSGTLGTIITIITILGVLGSSVITALFGFGWFLEWWNGGPDGQKFELASFMLKITFPYLWFITFTALSGAIL
NTLGKFAVAAFTPVFLNVAIISCAIFVSPHLQQPEIGLAIGVFLGGAIQFLFQIPFLHKEKLLVKPTWNWHHPGVVKIRV
LMIPALFGVSVSQINLLLDTFIASFLQTGSISWLYYSDRLLEFPLGLFGIAIATVILPSLSSSHVTKSIDDFAKTLDWGM
RMVCILGFPAMLGLIILAEPMLRVLFMRGEFVAHDVAMASMSLWAYGSGLLSFMMVKILAPGYYARQDTRTPVKYGMIAM
GSNMVLNIIFAIPYGYVGLAIATSISATLNAGLLWFGLYQKGIYQRQKDSVSVLLRIIIAGLVMAAGLVAFNPALSEWSQ
LSWLEAALKLFYLIVAGAVLYLFALGLTGLRFRHFQIRMAK

Sequences:

>Translated_521_residues
MSKKLLRSGLIVSSMTLISRILGLLRDVVIANLMGAGAAADVFFFANKIPNFLRRLFAEGAFAQAFVPVLTEYEKQHSFD
EVKKLVAAVSGTLGTIITIITILGVLGSSVITALFGFGWFLEWWNGGPDGQKFELASFMLKITFPYLWFITFTALSGAIL
NTLGKFAVAAFTPVFLNVAIISCAIFVSPHLQQPEIGLAIGVFLGGAIQFLFQIPFLHKEKLLVKPTWNWHHPGVVKIRV
LMIPALFGVSVSQINLLLDTFIASFLQTGSISWLYYSDRLLEFPLGLFGIAIATVILPSLSSSHVTKSIDDFAKTLDWGM
RMVCILGFPAMLGLIILAEPMLRVLFMRGEFVAHDVAMASMSLWAYGSGLLSFMMVKILAPGYYARQDTRTPVKYGMIAM
GSNMVLNIIFAIPYGYVGLAIATSISATLNAGLLWFGLYQKGIYQRQKDSVSVLLRIIIAGLVMAAGLVAFNPALSEWSQ
LSWLEAALKLFYLIVAGAVLYLFALGLTGLRFRHFQIRMAK
>Mature_520_residues
SKKLLRSGLIVSSMTLISRILGLLRDVVIANLMGAGAAADVFFFANKIPNFLRRLFAEGAFAQAFVPVLTEYEKQHSFDE
VKKLVAAVSGTLGTIITIITILGVLGSSVITALFGFGWFLEWWNGGPDGQKFELASFMLKITFPYLWFITFTALSGAILN
TLGKFAVAAFTPVFLNVAIISCAIFVSPHLQQPEIGLAIGVFLGGAIQFLFQIPFLHKEKLLVKPTWNWHHPGVVKIRVL
MIPALFGVSVSQINLLLDTFIASFLQTGSISWLYYSDRLLEFPLGLFGIAIATVILPSLSSSHVTKSIDDFAKTLDWGMR
MVCILGFPAMLGLIILAEPMLRVLFMRGEFVAHDVAMASMSLWAYGSGLLSFMMVKILAPGYYARQDTRTPVKYGMIAMG
SNMVLNIIFAIPYGYVGLAIATSISATLNAGLLWFGLYQKGIYQRQKDSVSVLLRIIIAGLVMAAGLVAFNPALSEWSQL
SWLEAALKLFYLIVAGAVLYLFALGLTGLRFRHFQIRMAK

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family [H]

Homologues:

Organism=Escherichia coli, GI1787309, Length=515, Percent_Identity=40.5825242718447, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004268 [H]

Pfam domain/function: PF03023 MVIN [H]

EC number: NA

Molecular weight: Translated: 57221; Mature: 57090

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECC
>Mature Secondary Structure 
SKKLLRSGLIVSSMTLISRILGLLRDVVIANLMGAGAAADVFFFANKIPNFLRRLFAEG
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
AFAQAFVPVLTEYEKQHSFDEVKKLVAAVSGTLGTIITIITILGVLGSSVITALFGFGWF
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEWWNGGPDGQKFELASFMLKITFPYLWFITFTALSGAILNTLGKFAVAAFTPVFLNVAI
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISCAIFVSPHLQQPEIGLAIGVFLGGAIQFLFQIPFLHKEKLLVKPTWNWHHPGVVKIRV
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHEEHH
LMIPALFGVSVSQINLLLDTFIASFLQTGSISWLYYSDRLLEFPLGLFGIAIATVILPSL
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCC
SSSHVTKSIDDFAKTLDWGMRMVCILGFPAMLGLIILAEPMLRVLFMRGEFVAHDVAMAS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MSLWAYGSGLLSFMMVKILAPGYYARQDTRTPVKYGMIAMGSNMVLNIIFAIPYGYVGLA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IATSISATLNAGLLWFGLYQKGIYQRQKDSVSVLLRIIIAGLVMAAGLVAFNPALSEWSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
LSWLEAALKLFYLIVAGAVLYLFALGLTGLRFRHFQIRMAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9457888; 10952301 [H]