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The map label for this gene is tas [H]

Identifier: 119946868

GI number: 119946868

Start: 4026137

End: 4027189

Strand: Direct

Name: tas [H]

Synonym: Ping_3262

Alternate gene names: 119946868

Gene position: 4026137-4027189 (Clockwise)

Preceding gene: 119946866

Following gene: 119946872

Centisome position: 88.3

GC content: 43.59

Gene sequence:

>1053_bases
ATGGAGTTTACAACGTTGGGAAGCAGTGGACTTCCAATATCAAAAGTCTGTTTAGGATCGATGACTTGGGGATTACAAAA
TAATCAACAGGATGCAAATCAGCAAATAGACTATGCCATTAGCCAGGGTATTAATTTTATTGATACAGCTGAAATGTATG
CAGTGCCGCCCTCGCCCGATACCTATGGAAAAACAGAAAGCATTCTGGGTAACTGGCTGGCGGAAAATAAAAATAAGCGT
AAAGATCTGATCATTGCCACTAAAATAGCCGGTGCCGGTGTGCCCTGGATACGTGATGGTGGACCTATTACGGGTGATGC
AGTTGTGGCAGCGGTAGATGCTTCTCTGAAACGTTTACAGACTGATTATATCGATCTTTATCAGCTGCATTGGCCAAATC
GAACTTCTCCCCATTTTAACAAACACTGGCCAAATCAATTAACATTCAGTGAGGTCAGCGCAGAGGATCACACTGCACAA
ATGTTAGATATTTTACAAGGGCTTAACCGCTGCGTTAAAGCCGGGAAAATACGTCATTGCGGATTATCTGACGACACCCC
TTGGGGCATTAATACCTACCTTAAATTAAGCGAAAAACACGATCTGCCAAGAATGGTTTCAATACAAAATGAATTTAGCT
TACTGCATGCTAAGGACTGGCCTTATTTAATAGAAAACTGTATCCATGAAGATATTGCTTATTTACCATGGTCCCCGCTT
GCGGGTGGGATGCTAAGCGGTAAATATCTCAATGGTGCCCGTCCAGAGGGCAGTCGCTGGACATTGGAGCAGCGTAATGG
TTTATTCCGCGATACACCGGCGGCACAAAAAGCAATTTCAGCCTATGCCGAGATAGCGAAACAAAACGGCTTTACGCCCG
CTCAATTAGCGCTCGCCTGGTGCAATCAAGTTGATGGTGTCACCTCAACTATTATTGGCGCGACAAATATCAACCAATTA
CAGGACGATATTAAGGCATTTTCAATGCCCTTAAACCAACAAGCGCTCATTGATATAGAGTCTGTCTTTAAAACCTACCC
TGTGCCTTTTTAA

Upstream 100 bases:

>100_bases
TCAGTCATTTAAACAGTATAGTATTTGAATACTGTTATTTACGACAACCAATATAATTTATTTTTAGCTTGTGATATTAA
CATCTATTTAAGGAATCAGT

Downstream 100 bases:

>100_bases
ACTAAACGCATAAACCAGAAAACCACCGCTAATTAAATTGGCGGTGGTTTTCTATGTACTTCAAGCTGCATCTGCCTGCG
CTATTTATTGCACAAATTCA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MEFTTLGSSGLPISKVCLGSMTWGLQNNQQDANQQIDYAISQGINFIDTAEMYAVPPSPDTYGKTESILGNWLAENKNKR
KDLIIATKIAGAGVPWIRDGGPITGDAVVAAVDASLKRLQTDYIDLYQLHWPNRTSPHFNKHWPNQLTFSEVSAEDHTAQ
MLDILQGLNRCVKAGKIRHCGLSDDTPWGINTYLKLSEKHDLPRMVSIQNEFSLLHAKDWPYLIENCIHEDIAYLPWSPL
AGGMLSGKYLNGARPEGSRWTLEQRNGLFRDTPAAQKAISAYAEIAKQNGFTPAQLALAWCNQVDGVTSTIIGATNINQL
QDDIKAFSMPLNQQALIDIESVFKTYPVPF

Sequences:

>Translated_350_residues
MEFTTLGSSGLPISKVCLGSMTWGLQNNQQDANQQIDYAISQGINFIDTAEMYAVPPSPDTYGKTESILGNWLAENKNKR
KDLIIATKIAGAGVPWIRDGGPITGDAVVAAVDASLKRLQTDYIDLYQLHWPNRTSPHFNKHWPNQLTFSEVSAEDHTAQ
MLDILQGLNRCVKAGKIRHCGLSDDTPWGINTYLKLSEKHDLPRMVSIQNEFSLLHAKDWPYLIENCIHEDIAYLPWSPL
AGGMLSGKYLNGARPEGSRWTLEQRNGLFRDTPAAQKAISAYAEIAKQNGFTPAQLALAWCNQVDGVTSTIIGATNINQL
QDDIKAFSMPLNQQALIDIESVFKTYPVPF
>Mature_350_residues
MEFTTLGSSGLPISKVCLGSMTWGLQNNQQDANQQIDYAISQGINFIDTAEMYAVPPSPDTYGKTESILGNWLAENKNKR
KDLIIATKIAGAGVPWIRDGGPITGDAVVAAVDASLKRLQTDYIDLYQLHWPNRTSPHFNKHWPNQLTFSEVSAEDHTAQ
MLDILQGLNRCVKAGKIRHCGLSDDTPWGINTYLKLSEKHDLPRMVSIQNEFSLLHAKDWPYLIENCIHEDIAYLPWSPL
AGGMLSGKYLNGARPEGSRWTLEQRNGLFRDTPAAQKAISAYAEIAKQNGFTPAQLALAWCNQVDGVTSTIIGATNINQL
QDDIKAFSMPLNQQALIDIESVFKTYPVPF

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=359, Percent_Identity=27.5766016713092, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI4504825, Length=357, Percent_Identity=27.4509803921569, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI27436964, Length=358, Percent_Identity=26.2569832402235, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI27436962, Length=358, Percent_Identity=26.2569832402235, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI27436966, Length=358, Percent_Identity=26.2569832402235, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI27436971, Length=361, Percent_Identity=26.8698060941828, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI223718702, Length=336, Percent_Identity=24.4047619047619, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI41327764, Length=354, Percent_Identity=24.2937853107345, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789199, Length=354, Percent_Identity=43.2203389830509, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI87081735, Length=361, Percent_Identity=27.7008310249307, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1789375, Length=338, Percent_Identity=28.1065088757396, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788070, Length=356, Percent_Identity=25.8426966292135, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788081, Length=346, Percent_Identity=25.7225433526012, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=371, Percent_Identity=24.2587601078167, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319958, Length=340, Percent_Identity=23.2352941176471, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323998, Length=357, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319951, Length=359, Percent_Identity=22.5626740947075, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644950, Length=328, Percent_Identity=26.5243902439024, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38819; Mature: 38819

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFTTLGSSGLPISKVCLGSMTWGLQNNQQDANQQIDYAISQGINFIDTAEMYAVPPSPD
CCEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEECCCEEEECCCCC
TYGKTESILGNWLAENKNKRKDLIIATKIAGAGVPWIRDGGPITGDAVVAAVDASLKRLQ
CCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEECCCCCCCCCHHHHHHHHHHHHHH
TDYIDLYQLHWPNRTSPHFNKHWPNQLTFSEVSAEDHTAQMLDILQGLNRCVKAGKIRHC
HHHHHEEEEECCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEC
GLSDDTPWGINTYLKLSEKHDLPRMVSIQNEFSLLHAKDWPYLIENCIHEDIAYLPWSPL
CCCCCCCCCCCCEEEECCCCCCCHHEECCCHHHEEECCCCHHHHHHHHHHHHHHCCCCCC
AGGMLSGKYLNGARPEGSRWTLEQRNGLFRDTPAAQKAISAYAEIAKQNGFTPAQLALAW
CCCCCCCCCCCCCCCCCCCEEHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
CNQVDGVTSTIIGATNINQLQDDIKAFSMPLNQQALIDIESVFKTYPVPF
HHHCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEFTTLGSSGLPISKVCLGSMTWGLQNNQQDANQQIDYAISQGINFIDTAEMYAVPPSPD
CCEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEECCCEEEECCCCC
TYGKTESILGNWLAENKNKRKDLIIATKIAGAGVPWIRDGGPITGDAVVAAVDASLKRLQ
CCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEECCCCCCCCCHHHHHHHHHHHHHH
TDYIDLYQLHWPNRTSPHFNKHWPNQLTFSEVSAEDHTAQMLDILQGLNRCVKAGKIRHC
HHHHHEEEEECCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEC
GLSDDTPWGINTYLKLSEKHDLPRMVSIQNEFSLLHAKDWPYLIENCIHEDIAYLPWSPL
CCCCCCCCCCCCEEEECCCCCCCHHEECCCHHHEEECCCCHHHHHHHHHHHHHHCCCCCC
AGGMLSGKYLNGARPEGSRWTLEQRNGLFRDTPAAQKAISAYAEIAKQNGFTPAQLALAW
CCCCCCCCCCCCCCCCCCCEEHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
CNQVDGVTSTIIGATNINQLQDDIKAFSMPLNQQALIDIESVFKTYPVPF
HHHCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]