Click here to switch to the map view.

The map label for this gene is glpD [H]

Identifier: 119946838

GI number: 119946838

Start: 3986650

End: 3988263

Strand: Reverse

Name: glpD [H]

Synonym: Ping_3232

Alternate gene names: 119946838

Gene position: 3988263-3986650 (Counterclockwise)

Preceding gene: 119946839

Following gene: 119946837

Centisome position: 87.47

GC content: 38.85

Gene sequence:

>1614_bases
ATGAGCCTCAATCGAATAAACAATATTAAGCAACTGGCTGAAGATGAGCTAGATGTACTTATTTTAGGCGGTGGTATCAA
TGGTGCTGTTGCAGCTGCATCTTTGGCTGCTAAAGGTGCTAAAGTTGGCCTTATTGATAAGGGAGATTTTGCAGGAGCAA
CGAGCTCTAATTCATCGAATCTTGCATGGGGTGGTATCAAATACCTGGAGAGCCATGAATATTTATTAGTTAATAAGCTT
TGTAAAAGCCGTAACAACCTTATGAGACATTATCCGTCATCGGTTACTGAGGTTCGTTTCTTAACAACTATTCAAAAAGG
TTTTCGTTTTCCTGTCTGGTTTGTGTTTATGGGGACTTTGGCTTATTGGTTATTTGGACGATTATTTACGATGGCACCTA
AGTATCTTACTCGAAATGCTATCAAGAAATTAGAGCCAAGCATTAAGACAGAGGGCGCACAAGCAGGTTTTGAATATTCA
GATGCATTCTTAAAAGATAATGACTCACGTTTTGTTTTTAATTTTATAACGGCTGCTGCAAAAAAATCGGCGGCTGTTGC
TAACTATGTAGAATCGGTAAATGCCGTTCGTGAAAACGGACTATGGGTAATACAAGCGAAAGATACTACCAATAATAAAA
TATTCACTATTAAAGCGAAAACACTGATCAATGCCTGTGGTCCTTTGGTTGACCAAGTTAATAAAGGGTCTGAGCAGAAA
ACATCACATCATCATTTATTTTCTAAGGGTGTTCATTTAACCGTTGATCGTATTTCAAAAGAACACCGTGTATTGGCATT
TTTTGCCAGTGATGGGCGTTTATTCTTTGTCTTACCTATGGGAAATAAAACCTGTATTGGCACAACAGATAATCAAGTTG
AGAGTCATCAAACATCGGTAACCGACGAAGATCGTCAATTTATTCTCGATAATGCCAATGCCTTATTAGAATTAGATAAG
CCGCTAACCAAAGCTGACATTATTGCAGAGCGGTGTGGTGTACGACCATTAGCGATTGAAGCCGAAGAAGGTGTTGCTGA
TTGGGTTGCCTTGTCACGTAAGCATGCAATAGATGTTAATAAAGCCGATAAACACATTAGTATTTTTGGTGGTAAGCTGA
CGGATTGTATTAACGTAGGTGAAGAAATTGCAGAGATAGTTAAAAGTTTATCTATTCCACTGCCAAAATCAGAATCAATC
TGGTATGGCGAGCCAGCTGACTCAGTTAAAGCAAAATTTATGAGCGCTATTGAAGAATTTAATATTGATAAATTGACTCC
AAAAGGAGCTATTGAGCCTTTATCGGGTCGTTTCTGGCGTCGTTATGGTGAAGATGCTTTTATTCTATTGGAAGCTATTA
AGCAGAACCCTGAAAAGGCAAATCTAGCACTTGAACATACAGAGTTTACTTGGGCTGAAATCGATTGGGTAGCCGACCAT
GAAATGATTGTTAACCTCGATGATCTATTGCGTAGACGTTCAAAAGCAACCCTTGTTATTCGTAAAGAATATTTAGATAA
TGCAAAAGGACTGGAAGCTGTCAGCGAACGTATTTTTGGTGAAAACGCGCAGCAAAAAGTCGCCGAGTTTCGCAGTACAG
CCAACTTCAATTGA

Upstream 100 bases:

>100_bases
TCTGCTAATAATCATATTAATTAGAACGACTATATGCTCTAATGTGAGCGGAAACGAACATTATTGTGAGCTATCGAACA
TTTAAATCAAGGATTCCGAA

Downstream 100 bases:

>100_bases
GTATAAATTTAATAGCCACTTGCTCAGCTTGTGTACTAACGTTAAAGAGTAACCTTACCTAGAGTAACTAGGCAAGGTTA
CTCTTTAACTATCAATTTAT

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MSLNRINNIKQLAEDELDVLILGGGINGAVAAASLAAKGAKVGLIDKGDFAGATSSNSSNLAWGGIKYLESHEYLLVNKL
CKSRNNLMRHYPSSVTEVRFLTTIQKGFRFPVWFVFMGTLAYWLFGRLFTMAPKYLTRNAIKKLEPSIKTEGAQAGFEYS
DAFLKDNDSRFVFNFITAAAKKSAAVANYVESVNAVRENGLWVIQAKDTTNNKIFTIKAKTLINACGPLVDQVNKGSEQK
TSHHHLFSKGVHLTVDRISKEHRVLAFFASDGRLFFVLPMGNKTCIGTTDNQVESHQTSVTDEDRQFILDNANALLELDK
PLTKADIIAERCGVRPLAIEAEEGVADWVALSRKHAIDVNKADKHISIFGGKLTDCINVGEEIAEIVKSLSIPLPKSESI
WYGEPADSVKAKFMSAIEEFNIDKLTPKGAIEPLSGRFWRRYGEDAFILLEAIKQNPEKANLALEHTEFTWAEIDWVADH
EMIVNLDDLLRRRSKATLVIRKEYLDNAKGLEAVSERIFGENAQQKVAEFRSTANFN

Sequences:

>Translated_537_residues
MSLNRINNIKQLAEDELDVLILGGGINGAVAAASLAAKGAKVGLIDKGDFAGATSSNSSNLAWGGIKYLESHEYLLVNKL
CKSRNNLMRHYPSSVTEVRFLTTIQKGFRFPVWFVFMGTLAYWLFGRLFTMAPKYLTRNAIKKLEPSIKTEGAQAGFEYS
DAFLKDNDSRFVFNFITAAAKKSAAVANYVESVNAVRENGLWVIQAKDTTNNKIFTIKAKTLINACGPLVDQVNKGSEQK
TSHHHLFSKGVHLTVDRISKEHRVLAFFASDGRLFFVLPMGNKTCIGTTDNQVESHQTSVTDEDRQFILDNANALLELDK
PLTKADIIAERCGVRPLAIEAEEGVADWVALSRKHAIDVNKADKHISIFGGKLTDCINVGEEIAEIVKSLSIPLPKSESI
WYGEPADSVKAKFMSAIEEFNIDKLTPKGAIEPLSGRFWRRYGEDAFILLEAIKQNPEKANLALEHTEFTWAEIDWVADH
EMIVNLDDLLRRRSKATLVIRKEYLDNAKGLEAVSERIFGENAQQKVAEFRSTANFN
>Mature_536_residues
SLNRINNIKQLAEDELDVLILGGGINGAVAAASLAAKGAKVGLIDKGDFAGATSSNSSNLAWGGIKYLESHEYLLVNKLC
KSRNNLMRHYPSSVTEVRFLTTIQKGFRFPVWFVFMGTLAYWLFGRLFTMAPKYLTRNAIKKLEPSIKTEGAQAGFEYSD
AFLKDNDSRFVFNFITAAAKKSAAVANYVESVNAVRENGLWVIQAKDTTNNKIFTIKAKTLINACGPLVDQVNKGSEQKT
SHHHLFSKGVHLTVDRISKEHRVLAFFASDGRLFFVLPMGNKTCIGTTDNQVESHQTSVTDEDRQFILDNANALLELDKP
LTKADIIAERCGVRPLAIEAEEGVADWVALSRKHAIDVNKADKHISIFGGKLTDCINVGEEIAEIVKSLSIPLPKSESIW
YGEPADSVKAKFMSAIEEFNIDKLTPKGAIEPLSGRFWRRYGEDAFILLEAIKQNPEKANLALEHTEFTWAEIDWVADHE
MIVNLDDLLRRRSKATLVIRKEYLDNAKGLEAVSERIFGENAQQKVAEFRSTANFN

Specific function: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses molecular oxygen or nitrate as electron acceptor [H]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=389, Percent_Identity=28.7917737789203, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI285002231, Length=389, Percent_Identity=28.7917737789203, Blast_Score=153, Evalue=5e-37,
Organism=Escherichia coli, GI2367226, Length=522, Percent_Identity=29.3103448275862, Blast_Score=158, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI115534726, Length=520, Percent_Identity=26.3461538461538, Blast_Score=142, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17509253, Length=387, Percent_Identity=29.1989664082687, Blast_Score=129, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6322036, Length=593, Percent_Identity=25.8010118043845, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI161077125, Length=415, Percent_Identity=28.433734939759, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24653942, Length=415, Percent_Identity=28.433734939759, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24653944, Length=415, Percent_Identity=28.433734939759, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI20130025, Length=415, Percent_Identity=28.433734939759, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24586295, Length=338, Percent_Identity=23.3727810650888, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19921278, Length=346, Percent_Identity=23.9884393063584, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 59767; Mature: 59636

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNRINNIKQLAEDELDVLILGGGINGAVAAASLAAKGAKVGLIDKGDFAGATSSNSSN
CCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCC
LAWGGIKYLESHEYLLVNKLCKSRNNLMRHYPSSVTEVRFLTTIQKGFRFPVWFVFMGTL
CEECCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
AYWLFGRLFTMAPKYLTRNAIKKLEPSIKTEGAQAGFEYSDAFLKDNDSRFVFNFITAAA
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCEEHHHHHHHHH
KKSAAVANYVESVNAVRENGLWVIQAKDTTNNKIFTIKAKTLINACGPLVDQVNKGSEQK
HHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCC
TSHHHLFSKGVHLTVDRISKEHRVLAFFASDGRLFFVLPMGNKTCIGTTDNQVESHQTSV
HHHHHHHHCCCEEEHHHCCCCCEEEEEEECCCEEEEEEECCCCEEECCCCCHHHHHHCCC
TDEDRQFILDNANALLELDKPLTKADIIAERCGVRPLAIEAEEGVADWVALSRKHAIDVN
CCCCHHEEECCCCEEEEECCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCC
KADKHISIFGGKLTDCINVGEEIAEIVKSLSIPLPKSESIWYGEPADSVKAKFMSAIEEF
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHC
NIDKLTPKGAIEPLSGRFWRRYGEDAFILLEAIKQNPEKANLALEHTEFTWAEIDWVADH
CCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCHHCEEEEECCCEEEEEEEEECC
EMIVNLDDLLRRRSKATLVIRKEYLDNAKGLEAVSERIFGENAQQKVAEFRSTANFN
CEEECHHHHHHHCCCCEEEEEHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLNRINNIKQLAEDELDVLILGGGINGAVAAASLAAKGAKVGLIDKGDFAGATSSNSSN
CCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCC
LAWGGIKYLESHEYLLVNKLCKSRNNLMRHYPSSVTEVRFLTTIQKGFRFPVWFVFMGTL
CEECCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
AYWLFGRLFTMAPKYLTRNAIKKLEPSIKTEGAQAGFEYSDAFLKDNDSRFVFNFITAAA
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCEEHHHHHHHHH
KKSAAVANYVESVNAVRENGLWVIQAKDTTNNKIFTIKAKTLINACGPLVDQVNKGSEQK
HHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCC
TSHHHLFSKGVHLTVDRISKEHRVLAFFASDGRLFFVLPMGNKTCIGTTDNQVESHQTSV
HHHHHHHHCCCEEEHHHCCCCCEEEEEEECCCEEEEEEECCCCEEECCCCCHHHHHHCCC
TDEDRQFILDNANALLELDKPLTKADIIAERCGVRPLAIEAEEGVADWVALSRKHAIDVN
CCCCHHEEECCCCEEEEECCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCC
KADKHISIFGGKLTDCINVGEEIAEIVKSLSIPLPKSESIWYGEPADSVKAKFMSAIEEF
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHC
NIDKLTPKGAIEPLSGRFWRRYGEDAFILLEAIKQNPEKANLALEHTEFTWAEIDWVADH
CCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCHHCEEEEECCCEEEEEEEEECC
EMIVNLDDLLRRRSKATLVIRKEYLDNAKGLEAVSERIFGENAQQKVAEFRSTANFN
CEEECHHHHHHHCCCCEEEEEHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1987111; 9278503; 3045087; 3045764 [H]