Click here to switch to the map view.

The map label for this gene is gpsA

Identifier: 119946813

GI number: 119946813

Start: 3962694

End: 3963698

Strand: Reverse

Name: gpsA

Synonym: Ping_3207

Alternate gene names: 119946813

Gene position: 3963698-3962694 (Counterclockwise)

Preceding gene: 119946814

Following gene: 119946810

Centisome position: 86.93

GC content: 44.78

Gene sequence:

>1005_bases
ATGGCAGATAATATAGCCATTACAGTCTTAGGGGCGGGATCATATGGCTCCGCCCTTGCTGTATCTTTGGCAAGAAACGG
TCATCCCACCTTGCTTTGGGGACATCAAGAAGATCATATCAAACGGTTACAAGCTGATCGCGAAAACAAAAAGTTTTTGC
CAAATATTAAATTTCCGGAACTATTAACACCGGAAGTTAATTTAAAGGTTTGTTTAGCTGCCACTCGCAATATTCTGTTG
GTAGTCCCAAGCCATGTTTTTGCACTTGTTTTACAACAAATAAAACCATTTCTTACCCCGCAGCACCGCATTGCCTGGGC
GACAAAAGGGTTAGAAGCCAAAACAGGGCGTTTATTGCAGGAAGTGGCTACGGACATCTTAGGGCAACATTACCCTTTAG
CGGTCATTTCCGGTCCAACTTTTGCGATGGAAGTTGCGAAAGGATTACCGACCGCAGTGGCTGTCGCTGGATCTGAAAGC
AAGTTTACTCAGGATATTGCCGCTCTCTTTCATAATAACCGTAATTTCAGAACCTATATTTCAGATGATTTCACTGCTGT
ACAACTAGGTGGTGCAGTGAAAAATGTGATTGCAATAGGGGCTGGCCTCGCCGATGGTTTAGGTTTTGGTGCAAATGCCC
GTACCGCATTGATTACACGCGGCTTGGCTGAATTAACGCGTTTGGGTGTGGCGTTAGGCGCTAAAGAATCCTCTTTTATG
GGCATGGCAGGTCTGGGTGATCTGGTATTAACTTGTACCGATAATCAATCTCGCAATCGCCGTTTTGGACTTGCTTTGGG
GCAGGGTAAAGGGATTAACGCAGCGCAAATTGAAATAGGTCAAGTGGTAGAAGGTTATCGAAATACCGAAGAGGTGTATA
ACTTGTCGCATCGGATTGGCATTGAAATGCCCATTTGTGAACAAATTTATTATGTCTTATATCAGGATAAAGCCGTCAAA
CAAGCCGCGATGGACTTGTTATCCCGTAGCCCAAAGGACGAGTGA

Upstream 100 bases:

>100_bases
TTGCAACGGTCTGTATTACGTAAACAAGCTAAATTAGATTCTTAATAAATTACTGAACAGTTAAACACAAGTTTAGTGAT
TATAACGAGTAGGTATTTAA

Downstream 100 bases:

>100_bases
TTATTCTTTTCTAATCGCTGTTATGGTTGGTTGATTTTATGCATTAAAAAAGGCTTCTTATTTGAAGCCTTTTTTATTTG
CCGTGTAAAATTTATGACGC

Product: glycerol-3-phosphate dehydrogenase (NAD(P)(+))

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MADNIAITVLGAGSYGSALAVSLARNGHPTLLWGHQEDHIKRLQADRENKKFLPNIKFPELLTPEVNLKVCLAATRNILL
VVPSHVFALVLQQIKPFLTPQHRIAWATKGLEAKTGRLLQEVATDILGQHYPLAVISGPTFAMEVAKGLPTAVAVAGSES
KFTQDIAALFHNNRNFRTYISDDFTAVQLGGAVKNVIAIGAGLADGLGFGANARTALITRGLAELTRLGVALGAKESSFM
GMAGLGDLVLTCTDNQSRNRRFGLALGQGKGINAAQIEIGQVVEGYRNTEEVYNLSHRIGIEMPICEQIYYVLYQDKAVK
QAAMDLLSRSPKDE

Sequences:

>Translated_334_residues
MADNIAITVLGAGSYGSALAVSLARNGHPTLLWGHQEDHIKRLQADRENKKFLPNIKFPELLTPEVNLKVCLAATRNILL
VVPSHVFALVLQQIKPFLTPQHRIAWATKGLEAKTGRLLQEVATDILGQHYPLAVISGPTFAMEVAKGLPTAVAVAGSES
KFTQDIAALFHNNRNFRTYISDDFTAVQLGGAVKNVIAIGAGLADGLGFGANARTALITRGLAELTRLGVALGAKESSFM
GMAGLGDLVLTCTDNQSRNRRFGLALGQGKGINAAQIEIGQVVEGYRNTEEVYNLSHRIGIEMPICEQIYYVLYQDKAVK
QAAMDLLSRSPKDE
>Mature_333_residues
ADNIAITVLGAGSYGSALAVSLARNGHPTLLWGHQEDHIKRLQADRENKKFLPNIKFPELLTPEVNLKVCLAATRNILLV
VPSHVFALVLQQIKPFLTPQHRIAWATKGLEAKTGRLLQEVATDILGQHYPLAVISGPTFAMEVAKGLPTAVAVAGSESK
FTQDIAALFHNNRNFRTYISDDFTAVQLGGAVKNVIAIGAGLADGLGFGANARTALITRGLAELTRLGVALGAKESSFMG
MAGLGDLVLTCTDNQSRNRRFGLALGQGKGINAAQIEIGQVVEGYRNTEEVYNLSHRIGIEMPICEQIYYVLYQDKAVKQ
AAMDLLSRSPKDE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=340, Percent_Identity=29.1176470588235, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI24307999, Length=355, Percent_Identity=27.3239436619718, Blast_Score=108, Evalue=6e-24,
Organism=Escherichia coli, GI1790037, Length=331, Percent_Identity=64.3504531722054, Blast_Score=448, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI32564399, Length=320, Percent_Identity=29.0625, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32564403, Length=329, Percent_Identity=28.2674772036474, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI193210136, Length=329, Percent_Identity=28.2674772036474, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17507425, Length=355, Percent_Identity=24.7887323943662, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193210134, Length=194, Percent_Identity=34.020618556701, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324513, Length=344, Percent_Identity=26.1627906976744, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320181, Length=346, Percent_Identity=27.1676300578035, Blast_Score=105, Evalue=8e-24,
Organism=Drosophila melanogaster, GI17136202, Length=326, Percent_Identity=29.4478527607362, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI17136200, Length=326, Percent_Identity=29.4478527607362, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI17136204, Length=326, Percent_Identity=29.4478527607362, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI22026922, Length=345, Percent_Identity=20.8695652173913, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45551945, Length=272, Percent_Identity=27.9411764705882, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281362270, Length=272, Percent_Identity=27.9411764705882, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648969, Length=210, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_PSYIN (A1SZH9)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944493.1
- ProteinModelPortal:   A1SZH9
- SMR:   A1SZH9
- STRING:   A1SZH9
- GeneID:   4624816
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3207
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- PhylomeDB:   A1SZH9
- BioCyc:   PING357804:PING_3207-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 36029; Mature: 35898

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 194-194 BINDING 109-109 BINDING 109-109 BINDING 142-142 BINDING 258-258 BINDING 284-284

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADNIAITVLGAGSYGSALAVSLARNGHPTLLWGHQEDHIKRLQADRENKKFLPNIKFPE
CCCCEEEEEEECCCCCCCEEEEECCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCCC
LLTPEVNLKVCLAATRNILLVVPSHVFALVLQQIKPFLTPQHRIAWATKGLEAKTGRLLQ
CCCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHCCCCHHEEEHHCCCCHHHHHHHH
EVATDILGQHYPLAVISGPTFAMEVAKGLPTAVAVAGSESKFTQDIAALFHNNRNFRTYI
HHHHHHCCCCCCEEEECCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEE
SDDFTAVQLGGAVKNVIAIGAGLADGLGFGANARTALITRGLAELTRLGVALGAKESSFM
CCCCEEEECCHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
GMAGLGDLVLTCTDNQSRNRRFGLALGQGKGINAAQIEIGQVVEGYRNTEEVYNLSHRIG
CCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHEEHHHHHHHCCCHHHHHHHHHHCC
IEMPICEQIYYVLYQDKAVKQAAMDLLSRSPKDE
CCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ADNIAITVLGAGSYGSALAVSLARNGHPTLLWGHQEDHIKRLQADRENKKFLPNIKFPE
CCCEEEEEEECCCCCCCEEEEECCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCCC
LLTPEVNLKVCLAATRNILLVVPSHVFALVLQQIKPFLTPQHRIAWATKGLEAKTGRLLQ
CCCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHCCCCHHEEEHHCCCCHHHHHHHH
EVATDILGQHYPLAVISGPTFAMEVAKGLPTAVAVAGSESKFTQDIAALFHNNRNFRTYI
HHHHHHCCCCCCEEEECCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEE
SDDFTAVQLGGAVKNVIAIGAGLADGLGFGANARTALITRGLAELTRLGVALGAKESSFM
CCCCEEEECCHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
GMAGLGDLVLTCTDNQSRNRRFGLALGQGKGINAAQIEIGQVVEGYRNTEEVYNLSHRIG
CCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHEEHHHHHHHCCCHHHHHHHHHHCC
IEMPICEQIYYVLYQDKAVKQAAMDLLSRSPKDE
CCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA